BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 33d946377e09fd9d850309f8f9580ce1.SwissProt.fasta
17 sequences; 5,987 total letters
Query= ACIAD2377
Length=305
Score E
Sequences producing significant alignments: (Bits) Value
P72970 Uncharacterized RNA pseudouridine synthase slr1592 [Synech... 93.6 2e-25
P75485 Uncharacterized RNA pseudouridine synthase MG209 homolog [... 90.5 3e-24
Q8IZ73 Pseudouridylate synthase RPUSD2 [Homo sapiens] 90.9 1e-23
Q149F1 Pseudouridylate synthase RPUSD2 [Mus musculus] 88.6 7e-23
P47451 Uncharacterized RNA pseudouridine synthase MG209 [Mycoplas... 85.1 3e-22
Q12362 tRNA pseudouridine(32) synthase, cytoplasmic / Diaminohydr... 84.3 2e-21
Q87LD3 Dual-specificity RNA pseudouridine synthase RluA [Vibrio p... 80.9 4e-21
Q8DCG0 Dual-specificity RNA pseudouridine synthase RluA [Vibrio v... 80.9 4e-21
Q12069 tRNA pseudouridine(32) synthase, mitochondrial [Saccharomy... 80.9 2e-20
O25114 Uncharacterized RNA pseudouridine synthase HP_0347 [Helico... 79.0 4e-20
P53294 tRNA pseudouridine(31) synthase [Saccharomyces cerevisiae ... 76.6 5e-19
Q45826 Uncharacterized RNA pseudouridine synthase Caur_0901 [Chlo... 67.4 5e-16
P33640 Ribosomal large subunit pseudouridine synthase D [Pseudomo... 64.7 4e-15
P0AA37 Dual-specificity RNA pseudouridine synthase RluA [Escheric... 62.0 1e-14
O66114 Uncharacterized RNA pseudouridine synthase ZMO0505 [Zymomo... 60.5 4e-14
P33643 Ribosomal large subunit pseudouridine synthase D [Escheric... 60.8 8e-14
P65836 Ribosomal large subunit pseudouridine synthase D [Salmonel... 59.7 2e-13
>P72970 Uncharacterized RNA pseudouridine synthase slr1592 [Synechocystis
sp. (strain PCC 6803 / Kazusa)]
Length=291
Score = 93.6 bits (231), Expect = 2e-25
Identities = 67/235 (29%), Positives = 106/235 (45%), Gaps = 12/235 (5%)
Query 33 VFEFLCRHFPHISASEWQQRFNDGLVFDAQGHLLDLNSPYQANTHIFYYRFLAHEIHVPF 92
+ +F + + H WQ+R G + + G +D P QA + Y+R E VP
Sbjct 1 MLDFYSQRYLHSERQAWQERIEQGQI-EVDGKTVDPTYPLQAGQTLTYWRSPWVEPEVPL 59
Query 93 EHSILFENHDLLVVDKPHFLTISPTGKYVQETLLVRLKQQTGNEDLTPIHRLDRETAGVV 152
+ S+L + DL +DKP L + P G +V T+L +LK Q E L P+HRL T+G++
Sbjct 60 QLSVLHRDEDLWAIDKPSGLPVLPGGDFVYHTVLEQLKIQYPQESLFPLHRLGTGTSGLL 119
Query 153 LFCKRPESRGIYQTLFAKREVHKIYHAIAAYNPLITFPQTLRLCLEKGN-PF----YTMQ 207
L + R F + KIY + L P+ G P+ Y
Sbjct 120 LLGRSTLGRRELSRQFREHICRKIYRTVIGPCDL---PEKFECHQAIGKIPYPQLGYIYA 176
Query 208 VNPNGQ-VNSETRIECLAHNQQWAKYRLSPSTGKQHQLRLHLSFLNIPIKNDPFY 261
+ +G+ S RI + + W + + TG+ HQ+R+HL+ L P+ D Y
Sbjct 177 ASSHGKPAQSYGRILARSPEKTWLEVEI--RTGRPHQIRIHLASLGYPLLGDRLY 229
>P75485 Uncharacterized RNA pseudouridine synthase MG209 homolog
[Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype
1)]
Length=309
Score = 90.5 bits (223), Expect = 3e-24
Identities = 62/213 (29%), Positives = 107/213 (50%), Gaps = 7/213 (3%)
Query 92 FEHSILFENHDLLVVDKPHFLTISPTGKYVQETLLVRLKQQTGNEDLTPIHRLDRETAGV 151
F IL+E+ ++VV+KP+ L PT E+LL ++ + +HRLDR+T+GV
Sbjct 78 FPLDILYEDEQIMVVNKPNGLISHPTSFNESESLLGAALFHCNHQPVFLVHRLDRDTSGV 137
Query 152 VLFCKRPESRGIYQTLFAKREVHKIYHAIAAYNPLITFPQTLRLCLEK-GNPFYTMQV-- 208
++ K S Q +R + + Y A+ + PL + T+ LE+ GN +V
Sbjct 138 IMLAKNQSSLLHLQKQLQQRVMKRYYLALVHF-PLDSLSGTISAPLERVGNNKVMWKVGN 196
Query 209 NPNGQVNSETRIECLAHNQQWAKYRLSPSTGKQHQLRLHLSFLNIPIKNDPFYPVVEHKA 268
+ N N+ T+ L N++ A + TG+ HQ+R+HL F+ P+ NDP Y + K+
Sbjct 197 SSNKAKNAFTKFTVLNQNEKAALIKCELLTGRTHQIRVHLQFIKHPVYNDPLYGL---KS 253
Query 269 DDDFSAPLQLLAKELSFFDPITQSPLNFKSHYE 301
+ L A+++SF P + F++ +
Sbjct 254 EQATEYGQYLHAQQISFIHPTLNKEMGFEAQLD 286
Score = 18.1 bits (35), Expect = 5.0
Identities = 16/53 (30%), Positives = 19/53 (36%), Gaps = 3/53 (6%)
Query 36 FLCRHFPHISASEWQQRFNDGLVFDA--QGHLLDLNSPYQANTHIFYYRFLAH 86
F C H P + R G++ A Q LL L Q YY L H
Sbjct 117 FHCNHQP-VFLVHRLDRDTSGVIMLAKNQSSLLHLQKQLQQRVMKRYYLALVH 168
>Q8IZ73 Pseudouridylate synthase RPUSD2 [Homo sapiens]
Length=545
Score = 90.9 bits (224), Expect = 1e-23
Identities = 55/176 (31%), Positives = 89/176 (51%), Gaps = 21/176 (12%)
Query 96 ILFENHDLLVVDKPHFLTISPTGKYVQETLLVRLKQQTGNEDLTPIHRLDRETAGVVLFC 155
+L EN D++VVDKP + + P G++ T++ L ++ ++L P+HRLDR T+GV++F
Sbjct 225 LLAENEDVVVVDKPSSIPVHPCGRFRHNTVIFILGKEHQLKELHPLHRLDRLTSGVLMFA 284
Query 156 KRPESRGIYQTLFAKREVHKIY----------HAIAAYNPLITFPQTLRLCLEKGNPFYT 205
K R++ K Y + P++ + +C
Sbjct 285 KTAAVSERIHEQVRDRQLEKEYVCRVEGEFPTEEVTCKEPILVVSYKVGVC--------- 335
Query 206 MQVNPNGQVNSETRIECLAHNQQWAKYRLSPSTGKQHQLRLHLSFLNIPIKNDPFY 261
+V+P G+ ET + L++N Q + R P TG+ HQ+R+HL FL PI NDP Y
Sbjct 336 -RVDPRGK-PCETVFQRLSYNGQSSVVRCRPLTGRTHQIRVHLQFLGHPILNDPIY 389
>Q149F1 Pseudouridylate synthase RPUSD2 [Mus musculus]
Length=553
Score = 88.6 bits (218), Expect = 7e-23
Identities = 55/170 (32%), Positives = 89/170 (52%), Gaps = 9/170 (5%)
Query 96 ILFENHDLLVVDKPHFLTISPTGKYVQETLLVRLKQQTGNEDLTPIHRLDRETAGVVLFC 155
+L EN+D++V+DKP + + P G++ T++ L ++ ++L P+HRLDR T+GV++F
Sbjct 238 LLAENNDVVVIDKPSSIPVHPCGRFRHNTVIFILGKEHQLKELHPLHRLDRLTSGVLMFA 297
Query 156 KRPESRGIYQTLFAKREVHKIYHAIAAYNPLITFPQTLRLCLEK----GNPFYTMQVNPN 211
K R++ K Y A FP +C E +V+P
Sbjct 298 KTAAVSEKIHEQVRDRQLEKEYVCRVAGE----FPDKEVICKEPILVVSYKVGVCRVDPR 353
Query 212 GQVNSETRIECLAHNQQWAKYRLSPSTGKQHQLRLHLSFLNIPIKNDPFY 261
G+ ET + L++N + + + P TG+ HQ+R+HL FL PI NDP Y
Sbjct 354 GK-PCETVFQRLSYNGRSSVVQCRPLTGRTHQIRVHLQFLGHPILNDPIY 402
Score = 18.9 bits (37), Expect = 3.0
Identities = 13/37 (35%), Positives = 16/37 (43%), Gaps = 1/37 (3%)
Query 208 VNPNGQVNSETRIECLAHNQQWAKY-RLSPSTGKQHQ 243
V PNG S T E L + A + P +G Q Q
Sbjct 53 VQPNGDAGSNTSGEPLLERLEPAAVGKQVPESGDQAQ 89
>P47451 Uncharacterized RNA pseudouridine synthase MG209 [Mycoplasma
genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195
/ G37)]
Length=308
Score = 85.1 bits (209), Expect = 3e-22
Identities = 58/208 (28%), Positives = 96/208 (46%), Gaps = 6/208 (3%)
Query 96 ILFENHDLLVVDKPHFLTISPTGKYVQETLLVRLKQQTGNEDLTPIHRLDRETAGVVLFC 155
+LFE+ DL+V++KP L PT + +LL + +HRLDR+T+G ++ C
Sbjct 82 VLFEDKDLMVINKPSGLLTHPTTFNEKASLLAACIFHNNKNPVYLVHRLDRDTSGAIVVC 141
Query 156 KRPESRGIYQTLFAKREVHKIYHAIAAYNPLITFPQTLRLCLEKGNPFYTM-QVNPNGQV 214
K S Q R + + Y A+ + P ++ L + N M ++ +
Sbjct 142 KNQASLLNLQNQLQNRTLKRYYVALVHF-PFNALTGSINAPLARVNNNKVMFKIAQTAKA 200
Query 215 NSE-TRIECLAHNQQWAKYRLSPSTGKQHQLRLHLSFLNIPIKNDPFYPVVEHKADDDFS 273
T+ + + N++ A L TG+ HQ+R+HL F+ P+ NDP Y + K D S
Sbjct 201 KQAITKFKVINQNEKAALISLELLTGRTHQIRVHLKFIQHPVYNDPLYGIKSEKKD---S 257
Query 274 APLQLLAKELSFFDPITQSPLNFKSHYE 301
L A + F P P++F + E
Sbjct 258 YGQFLHANRICFIHPTLNKPMDFHAPLE 285
Score = 18.9 bits (37), Expect = 2.8
Identities = 12/31 (39%), Positives = 15/31 (48%), Gaps = 3/31 (10%)
Query 62 QGHLLDLNSPYQANTHIFYYRFLAHEIHVPF 92
Q LL+L + Q T YY L +H PF
Sbjct 144 QASLLNLQNQLQNRTLKRYYVAL---VHFPF 171
>Q12362 tRNA pseudouridine(32) synthase, cytoplasmic / Diaminohydroxyphosphoribosylaminopyrimidine
deaminase [Saccharomyces
cerevisiae (strain ATCC 204508 / S288c)]
Length=591
Score = 84.3 bits (207), Expect = 2e-21
Identities = 59/212 (28%), Positives = 105/212 (50%), Gaps = 14/212 (7%)
Query 61 AQGHLLDLNSPYQANTHIFYYRFLAHEIH--------VPFEHSILFENHDLLVVDKPHFL 112
A+G + + P +T I + H++H P + I+FE+ D+LV+DKP +
Sbjct 122 AEGKVYLNDEPANLDTIIRDGDLITHKVHRHEPPVTSKPID--IVFEDEDILVIDKPSSI 179
Query 113 TISPTGKYVQETLLVRLKQQTGNEDLTPIHRLDRETAGVVLFCKRPESRGIYQTLFAKRE 172
+ PTG+Y T+ L++Q G + P +RLD+ T+G++ K P RE
Sbjct 180 PVHPTGRYRFNTITKMLERQLGYS-VHPCNRLDKPTSGLMFLAKTPLGADRMGDQMKARE 238
Query 173 VHKIYHA-IAAYNPL--ITFPQTLRLCLEKGNPFYTMQVNPNGQVNSETRIECLAHNQQW 229
V K Y A + P+ + + +R K +++ +++T + ++++ Q
Sbjct 239 VTKEYVARVKGEFPIGIVEVDKPVRSVNPKVALNAVCEMSDENAKHAKTVFQRVSYDGQT 298
Query 230 AKYRLSPSTGKQHQLRLHLSFLNIPIKNDPFY 261
+ + P TG+ HQ+R+HL +L PI NDP Y
Sbjct 299 SIVKCKPLTGRTHQIRVHLQYLGFPIANDPIY 330
>Q87LD3 Dual-specificity RNA pseudouridine synthase RluA [Vibrio
parahaemolyticus serotype O3:K6 (strain RIMD 2210633)]
Length=250
Score = 80.9 bits (198), Expect = 4e-21
Identities = 66/207 (32%), Positives = 97/207 (47%), Gaps = 27/207 (13%)
Query 96 ILFENHDLLVVDKPHFLTISPTGKYVQETLLVRLKQQTGNEDLTPIHRLDRETAGVVLFC 155
I+FE+ +L V+KP L +S G+ + + + Q D+ +HRLD T+G+++
Sbjct 16 IVFEDDHILAVNKPSGL-LSVPGRLAEHHDSMWSRLQEEYPDIQVVHRLDMSTSGLMVLA 74
Query 156 KRPESRGIYQTLFAKREVHKIYHAIAAYN----------PLIT-FPQT--LRLCLEKGNP 202
K + + F R HKIY+A + PLI +P ++C E G P
Sbjct 75 KNKRAESALKKQFQFRLTHKIYYARVWGHVEQEEGEIDLPLICDWPNRPLQKVCFEDGKP 134
Query 203 FYTM-QVNPNGQVNSETRIECLAHNQQWAKYRLSPSTGKQHQLRLHLSFLNIPIKNDPFY 261
T+ QV + T+ + RL P TG+ HQLR+H+ L PI D FY
Sbjct 135 SKTLFQVAKREEQEDGTKTTIV---------RLLPITGRSHQLRVHMQALGHPIVGDEFY 185
Query 262 PVVEHKADDDFSAPLQLLAKELSFFDP 288
E K FS L+L A ELSF+ P
Sbjct 186 ATEEAKV---FSERLELHASELSFYHP 209
>Q8DCG0 Dual-specificity RNA pseudouridine synthase RluA [Vibrio
vulnificus (strain CMCP6)]
Length=250
Score = 80.9 bits (198), Expect = 4e-21
Identities = 68/212 (32%), Positives = 103/212 (49%), Gaps = 37/212 (17%)
Query 96 ILFENHDLLVVDKPHFLTISPTGKYVQ--ETLLVRLKQQTGNEDLTPIHRLDRETAGVVL 153
I+FE+ +L V+KP L +S G+ + +++ RL++Q ++ +HRLD T+G+++
Sbjct 16 IIFEDDHILAVNKPSGL-LSVPGRLPEHHDSMWSRLQEQY--PEIQVVHRLDMSTSGLMV 72
Query 154 FCKRPESRGIYQTLFAKREVHKIYHA-----IAAYNPLITFPQTL--------RLCLEKG 200
F K + + F R HK+Y+A + A + +I P ++C E G
Sbjct 73 FAKNKRAEAALKKQFQYRLTHKVYYARVWGHVEADSGMIDLPLICDWPNRPMQKVCHEHG 132
Query 201 NPFYT-MQVNPNGQVNSETRIECLAHNQQWAKYRLSPSTGKQHQLRLHLSFLNIPIKNDP 259
P T QV + E A+ Q RL P TG+ HQLR+H+ L PI D
Sbjct 133 KPSQTAFQV---------AKREVHANGAQTTIMRLLPVTGRSHQLRVHMQALGHPIVGDE 183
Query 260 FYPVVEHKADDD---FSAPLQLLAKELSFFDP 288
FY A D FS L+L A ELSF+ P
Sbjct 184 FY------AQGDAFTFSERLELHAAELSFYHP 209
>Q12069 tRNA pseudouridine(32) synthase, mitochondrial [Saccharomyces
cerevisiae (strain ATCC 204508 / S288c)]
Length=462
Score = 80.9 bits (198), Expect = 2e-20
Identities = 51/173 (29%), Positives = 88/173 (51%), Gaps = 12/173 (7%)
Query 96 ILFENHDLLVVDKPHFLTISPTGKYVQETLLVRLKQQTGNEDLTPIHRLDRETAGVVLFC 155
++FE+ +++V+DKP + + PTG+Y T+ L+ G + P +RLDR T+G++
Sbjct 190 VIFEDDNIMVIDKPSGIPVHPTGRYRFNTITKMLQNNLGFV-VNPCNRLDRLTSGLMFLA 248
Query 156 KRPESRGIYQTLFAKREVHKIYHAIAAYNPLITFPQT-------LRLCLEKGNPFYTMQV 208
K P+ REV K Y A FP+T L+L + Q+
Sbjct 249 KTPKGADNIGDQLKAREVTKEYVAKVVGE----FPETEVIVEKPLKLIEPRLALNAVCQM 304
Query 209 NPNGQVNSETRIECLAHNQQWAKYRLSPSTGKQHQLRLHLSFLNIPIKNDPFY 261
+ G +++T ++++ + + + P TG+ HQ+R+HL +L PI NDP Y
Sbjct 305 DEKGAKHAKTVFNRISYDGKTSIVKCKPLTGRSHQIRVHLQYLGHPIANDPIY 357
>O25114 Uncharacterized RNA pseudouridine synthase HP_0347 [Helicobacter
pylori (strain ATCC 700392 / 26695)]
Length=298
Score = 79.0 bits (193), Expect = 4e-20
Identities = 66/209 (32%), Positives = 109/209 (52%), Gaps = 26/209 (12%)
Query 95 SILFENHDLLVVDKPHFLTISPTGKYVQETLLVRLKQQTGNEDLTPIHRLDRETAGVVLF 154
+++FE D V DKPH + P G + E+LL ++ G ++ P HRLD ET+G+VL
Sbjct 70 ALVFETKDFGVFDKPHQVYTHPKGYFYHESLLDCIQSHFG-KNAHPAHRLDYETSGLVLA 128
Query 155 CKRPESRGIYQTLFAKREVHKIYHAIA---------AYNPLITFPQTLRLCLEKGNPFYT 205
K +S + LF +++V K Y A+A P++T PQ ++ L
Sbjct 129 GKTLQSVKDLKALFMQKKVKKTYLALAHGLVEKSMKIDKPILT-PQNIQKDLH-----IR 182
Query 206 MQVNPNGQVNSETRIECLAHNQ--QWAKYRLSPSTGKQHQLRLHLSFLNIPIKNDPFYPV 263
+++P G+ S T +E L++N + +++P TG+ HQ+RLHLS ++ I + Y V
Sbjct 183 SKISPLGK-QSITLVEPLSYNPFLDISLLKITPLTGRTHQIRLHLSSVDHRIVGEGLYGV 241
Query 264 VEHKADD------DFSAPLQLL-AKELSF 285
+ A + + +APL +L A L F
Sbjct 242 ADENAREYLQLKRENNAPLLMLHAASLEF 270
>P53294 tRNA pseudouridine(31) synthase [Saccharomyces cerevisiae
(strain ATCC 204508 / S288c)]
Length=404
Score = 76.6 bits (187), Expect = 5e-19
Identities = 57/189 (30%), Positives = 89/189 (47%), Gaps = 26/189 (14%)
Query 95 SILFENHDLLVVDKPHFLTISPTGKYVQETLLVRLKQQTGNEDLTPIHRLDRETAGVVLF 154
+I+FE+ +LV+DKP + + PTG++ Q T+ LK D P +RLD+ T+G+++
Sbjct 120 NIVFEDESILVIDKPSGIPVHPTGQFYQNTITELLKLH--GVDALPCYRLDKITSGLLIL 177
Query 155 CKRPESRGIYQTLFAKREVHKIYHAIA----AYNPLI---------TFPQTLRLCLEKGN 201
K +S G Q R++ KIY A ++ LI TF T ++ +E
Sbjct 178 AKNSQSAGEIQKSIRSRDMIKIYLARVKGRFPHSELILDNENAAETTFEDTSKVTVEM-T 236
Query 202 PFYTMQVNPNGQVNSETR---------IECLAHNQQWAKYRLSPSTGKQHQLRLHLSFLN 252
P Y++ V T I +H + P TG+ HQ+R+HL+ L
Sbjct 237 PIYSIDPKRQFPVGLSTSKDAITKFYPIRYFSHADE-TVVACKPITGRTHQIRIHLARLG 295
Query 253 IPIKNDPFY 261
PI ND Y
Sbjct 296 HPIVNDSVY 304
>Q45826 Uncharacterized RNA pseudouridine synthase Caur_0901 [Chloroflexus
aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)]
Length=316
Score = 67.4 bits (163), Expect = 5e-16
Identities = 62/267 (23%), Positives = 113/267 (42%), Gaps = 34/267 (13%)
Query 15 VSASKAFLPLQPKEIFKSVFEFLCRHFPHISASEWQQRFNDGLV-FDAQ----------G 63
+ A + + + P + + + FL P +S ++ Q+ G V +D + G
Sbjct 10 LEAEERVVVVPPTQTAERIDRFLAGAMPDLSRAQVQRLIEQGFVLYDGRSPRASQPVRPG 69
Query 64 HLLDLNSPYQANTHIFYYRFLAHEIHVPFEHSILFENHDLLVVDKPHFLTISPTGKYVQE 123
++ L P T + + P +++E+ D+ V++KP + + P + +
Sbjct 70 AVIQLTIPPPIPTEL---------VAEPIPLDVVYEDADIAVINKPAGMVVHPAPGHPRG 120
Query 124 TL----LVRLKQQTGNEDLTP--IHRLDRETAGVVLFCKRPESRGIYQTLFAKREVHKIY 177
TL L R +L P +HRLDR+T+G+++ + ++ R + KIY
Sbjct 121 TLVNALLARYPDLAIGGELRPGIVHRLDRDTSGLLVIARHDQAMRSLVDQQQARRMRKIY 180
Query 178 HAIAAYNPLITFPQTLRLCLEKGNP---FYTMQVNPNGQVNSETRIECLAHNQQWAKYRL 234
A+ P P+T + G M V P+G+ + T L ++ +
Sbjct 181 QALVIGRP----PETGTIDAPIGRDPRDRLRMAVVPDGRP-ARTHYRLLDTFGDYSLLEV 235
Query 235 SPSTGKQHQLRLHLSFLNIPIKNDPFY 261
TG+ HQ+R+HL L PI DP Y
Sbjct 236 QLETGRTHQIRVHLRHLGYPIVGDPVY 262
>P33640 Ribosomal large subunit pseudouridine synthase D [Pseudomonas
aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116
/ JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)]
Length=320
Score = 64.7 bits (156), Expect = 4e-15
Identities = 50/174 (29%), Positives = 81/174 (47%), Gaps = 8/174 (5%)
Query 93 EHSILFENHDLLVVDKPHFLTISPTGKYVQETLLVRLKQQTGNEDLTP----IHRLDRET 148
E I++E+ +LV+DKP L + P + TLL L + P +HRLD++T
Sbjct 82 ELEIVYEDEHILVIDKPAGLVVHPAAGHQDGTLLNALLYHVPDIANVPRAGIVHRLDKDT 141
Query 149 AGVVLFCKRPESRGIYQTLFAKREVHKIYHAIAAYNPLITFPQTLRLCLEK-GNPFYTMQ 207
G+++ K E+ R V +IY AI +IT T+ + + G M
Sbjct 142 TGLMVVAKTLEAHTKLVAQLQARSVSRIYEAIVI--GVITSGGTIDAPIGRHGVQRQKMA 199
Query 208 VNPNGQVNSETRIECLAHNQQWAKYRLSPSTGKQHQLRLHLSFLNIPIKNDPFY 261
V G+V + + L + R+ TG+ HQ+R+H+S + P+ DP Y
Sbjct 200 VVDAGKV-AVSHYRVLERFRAHTHTRVKLETGRTHQIRVHMSHIGYPLVGDPVY 252
>P0AA37 Dual-specificity RNA pseudouridine synthase RluA [Escherichia
coli (strain K12)]
Length=219
Score = 62.0 bits (149), Expect = 1e-14
Identities = 61/216 (28%), Positives = 94/216 (44%), Gaps = 29/216 (13%)
Query 96 ILFENHDLLVVDKPHFLTISPTGKYVQETLLVRLKQQTGNEDLTPIHRLDRETAGVVLFC 155
IL+++ ++VV+KP L +S G+ + V + Q +HRLD T+GV++
Sbjct 16 ILYQDDHIMVVNKPSGL-LSVPGRLEEHKDSVMTRIQRDYPQAESVHRLDMATSGVIVVA 74
Query 156 KRPESRGIYQTLFAKREVHKIYHAIAAYNP-----LITFPQTL--------RLCLEKGNP 202
+ + F +RE K Y A +P L+ P ++C E G P
Sbjct 75 LTKAAERELKRQFREREPKKQYVARVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKP 134
Query 203 FYTMQVNPNGQVNSETRIECLAHNQQWAKYRLSPSTGKQHQLRLHLSFLNIPIKNDPFYP 262
Q E +E A N A+ L P TG+ HQLR+H+ L PI D FY
Sbjct 135 ---------AQTEYEV-VEYAADNT--ARVVLKPITGRSHQLRVHMLALGHPILGDRFYA 182
Query 263 VVEHKADDDFSAPLQLLAKELSFFDPITQSPLNFKS 298
E +A + L L A+ L+ P + + FK+
Sbjct 183 SPEARA---MAPRLLLHAEMLTITHPAYGNSMTFKA 215
>O66114 Uncharacterized RNA pseudouridine synthase ZMO0505 [Zymomonas
mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)]
Length=219
Score = 60.5 bits (145), Expect = 4e-14
Identities = 60/210 (29%), Positives = 100/210 (48%), Gaps = 18/210 (9%)
Query 96 ILFENHDLLVVDKPHFLTISPT--GKYVQETLLVRLKQQTGNEDLTPIHRLDRETAGVVL 153
+LF + + +++DKP L ++ G E L L + +HRLDR+T+G +L
Sbjct 8 VLFIDAEAMIIDKPAGLPVTSVRDGSLSLENYLASLCFGFKRWP-SIVHRLDRDTSGCLL 66
Query 154 FCKRPESRGIYQTLFAKREVHKIYHAIAAYNP-----LITFPQTLRLCLEKGNPFYTMQV 208
+ P+ F++ +V K Y AI P +I P L++ K + +
Sbjct 67 LARNPKMHRRLSEAFSQGQVKKCYWAILEGVPEKNEGIIDLP-LLKISSPKSG--WRIVA 123
Query 209 NPNGQVNSETRIECLAHNQQWAKYRLSPSTGKQHQLRLHLSF-LNIPIKNDPFYPVVEHK 267
+ G+ + T E LA N+ + P TG+ HQLR+H + L +PI DPFY HK
Sbjct 124 DDKGK-RAVTHWEILAKNKGRSLVAFRPETGRTHQLRVHAATGLGLPIVGDPFYG--SHK 180
Query 268 ADDDFSAPLQLLAKELSFFD--PIT-QSPL 294
++ L + E++ + PIT ++PL
Sbjct 181 DENISRMMLHAHSLEIARLEKKPITAEAPL 210
>P33643 Ribosomal large subunit pseudouridine synthase D [Escherichia
coli (strain K12)]
Length=326
Score = 60.8 bits (146), Expect = 8e-14
Identities = 44/171 (26%), Positives = 84/171 (49%), Gaps = 8/171 (5%)
Query 96 ILFENHDLLVVDKPHFLTISPTGKYVQETLLVRLKQQTGNEDLTP----IHRLDRETAGV 151
I++E+ D+++++KP L + P T+L L P +HRLD++T G+
Sbjct 86 IVYEDEDIIIINKPRDLVVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGL 145
Query 152 VLFCKRPESRGIYQTLFAKREVHKIYHAIAAYNPLITFPQTLRLCLEKGNPFYT-MQVNP 210
++ K ++ +RE+ + Y A+A + +T T+ + + T M V+P
Sbjct 146 MVVAKTVPAQTRLVESLQRREITREYEAVAIGH--MTAGGTVDEPISRHPTKRTHMAVHP 203
Query 211 NGQVNSETRIECLAHNQQWAKYRLSPSTGKQHQLRLHLSFLNIPIKNDPFY 261
G+ + T + H + + RL TG+ HQ+R+H++ + P+ DP Y
Sbjct 204 MGKP-AVTHYRIMEHFRVHTRLRLRLETGRTHQIRVHMAHITHPLVGDPVY 253
>P65836 Ribosomal large subunit pseudouridine synthase D [Salmonella
typhimurium (strain LT2 / SGSC1412 / ATCC 700720)]
Length=326
Score = 59.7 bits (143), Expect = 2e-13
Identities = 57/223 (26%), Positives = 103/223 (46%), Gaps = 21/223 (9%)
Query 82 RFLAHEIHVPFEHSILFENHDLLVVDKPHFLTISPTGKYVQETLLVRLKQQTGNEDLTP- 140
RF A +I + I++E+ D+LV++KP L + P T+L L P
Sbjct 76 RFEAQDIPL----DIVYEDDDILVINKPRDLVVHPGAGNPDGTVLNALLHYYPPIADVPR 131
Query 141 ---IHRLDRETAGVVLFCKRPESRGIYQTLFAKREVHKIYHAIAAYNPLITFPQTLRLCL 197
+HRLD++T G+++ K ++ RE+ + Y A+A + +T T+ +
Sbjct 132 AGIVHRLDKDTTGLMVVAKTVPAQTRLVESLQLREITREYEAVAIGH--MTAGGTVNEPI 189
Query 198 EKGNPFYT-MQVNPNGQVNSETRIECLAHNQQWAKYRLSPSTGKQHQLRLHLSFLNIPIK 256
+ T M V+P G+ + T + H + + RL TG+ HQ+R+H++ + P+
Sbjct 190 SRHPTKRTHMSVHPMGKP-AVTHYRIMEHFRVHTRLRLRLETGRTHQIRVHMAHITHPLV 248
Query 257 NDPFY---PVVEHKADDDFSAPLQ------LLAKELSFFDPIT 290
D Y P A ++F + L+ L A L + P++
Sbjct 249 GDQVYGGRPRPPKGASEEFISTLRKFDRQALHATMLRLYHPVS 291
Lambda K H a alpha
0.325 0.140 0.434 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1338504
Database: 33d946377e09fd9d850309f8f9580ce1.SwissProt.fasta
Posted date: Jun 3, 2024 12:10 AM
Number of letters in database: 5,987
Number of sequences in database: 17
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
