BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: c80497ead7802b24471d0993ca2374ca.SwissProt.fasta
20 sequences; 5,417 total letters
Query= ACIAD2452
Length=245
Score E
Sequences producing significant alignments: (Bits) Value
Q9I2T1 Hydroxyacylglutathione hydrolase [Pseudomonas aeruginosa (... 213 1e-72
B7VB64 Hydroxyacylglutathione hydrolase [Pseudomonas aeruginosa (... 213 1e-72
C3K9Q0 Hydroxyacylglutathione hydrolase [Pseudomonas fluorescens ... 212 4e-72
A6V707 Hydroxyacylglutathione hydrolase [Pseudomonas aeruginosa (... 209 7e-71
Q4KBH9 Hydroxyacylglutathione hydrolase [Pseudomonas fluorescens ... 206 7e-70
A4G7G5 Hydroxyacylglutathione hydrolase [Herminiimonas arsenicoxy... 204 4e-69
Q7NG34 Hydroxyacylglutathione hydrolase [Gloeobacter violaceus (s... 202 3e-68
Q3KE79 Hydroxyacylglutathione hydrolase [Pseudomonas fluorescens ... 202 3e-68
A4Y6B8 Hydroxyacylglutathione hydrolase [Shewanella putrefaciens ... 202 5e-68
Q60BX0 Hydroxyacylglutathione hydrolase [Methylococcus capsulatus... 200 2e-67
Q5E3G3 Hydroxyacylglutathione hydrolase [Aliivibrio fischeri (str... 184 2e-61
P0AC84 Hydroxyacylglutathione hydrolase GloB [Escherichia coli (s... 177 1e-58
Q8ZRM2 Hydroxyacylglutathione hydrolase [Salmonella typhimurium (... 166 2e-54
P96981 Hydroxyacylglutathione hydrolase [Rhodobacter capsulatus] 166 5e-54
Q16775 Hydroxyacylglutathione hydrolase, mitochondrial [Homo sapi... 165 3e-53
O35952 Hydroxyacylglutathione hydrolase, mitochondrial [Rattus no... 165 4e-53
O24496 Hydroxyacylglutathione hydrolase cytoplasmic [Arabidopsis ... 161 3e-52
Q9SID3 Hydroxyacylglutathione hydrolase 2, mitochondrial [Arabido... 162 6e-52
Q08889 Hydroxyacylglutathione hydrolase [Buchnera aphidicola subs... 152 7e-49
Q69ZP3 Probable hydrolase PNKD [Mus musculus] 154 3e-48
>Q9I2T1 Hydroxyacylglutathione hydrolase [Pseudomonas aeruginosa
(strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 /
LMG 12228 / 1C / PRS 101 / PAO1)]
Length=258
Score = 213 bits (543), Expect = 1e-72
Identities = 122/260 (47%), Positives = 156/260 (60%), Gaps = 24/260 (9%)
Query 5 QIDYIDVKNSLKNYIWILKDSHTQEIIVVDPTESSLVQQYCEKH-QVKIAQIWLTHWHKD 63
QID + N NYIW+L+D+ ++ VVDP ++ V+ + H +++ I +TH H D
Sbjct 3 QIDALPAFND--NYIWLLQDATSRRCAVVDPGDAKPVEAWLAAHPDWRLSDILVTHHHHD 60
Query 64 HIGGVPDLIDGSHIPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVV 123
H+GGV L + + V GP E KIP L+ + L E+ PGHTLGH+
Sbjct 61 HVGGVAALKELTGARVLGPANE--KIPARDLALEDGERVEVLGLVFEIFHVPGHTLGHIA 118
Query 124 YFIE-ETGSLFCGDTLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLANAE 182
Y+ ET LFCGDTLFA GCGR+FEG+ QM+HSL RLAALP T+VYCTHEYTL+N
Sbjct 119 YYHPAETPLLFCGDTLFAAGCGRLFEGTPAQMHHSLARLAALPANTRVYCTHEYTLSNLR 178
Query 183 FAVTVEPDNLALKERLKEVQSLRSRHQITLPSTIALELATNPFLRTES------------ 230
FA+ VEPDN AL+ER +E LR R +ITLPS I+LEL+TNPFLR
Sbjct 179 FALAVEPDNAALRERFEEATRLRERDRITLPSEISLELSTNPFLRVSENSVKKKADQRSG 238
Query 231 ------VEEFAKIRTLKDQF 244
E FA +R KDQF
Sbjct 239 QQNRTPEEVFAVLRAWKDQF 258
>B7VB64 Hydroxyacylglutathione hydrolase [Pseudomonas aeruginosa
(strain LESB58)]
Length=258
Score = 213 bits (543), Expect = 1e-72
Identities = 122/260 (47%), Positives = 156/260 (60%), Gaps = 24/260 (9%)
Query 5 QIDYIDVKNSLKNYIWILKDSHTQEIIVVDPTESSLVQQYCEKH-QVKIAQIWLTHWHKD 63
QID + N NYIW+L+D+ ++ VVDP ++ V+ + H +++ I +TH H D
Sbjct 3 QIDALPAFND--NYIWLLQDATSRRCAVVDPGDAKPVEAWLAAHPDWRLSDILVTHHHHD 60
Query 64 HIGGVPDLIDGSHIPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVV 123
H+GGV L + + V GP E KIP L+ + L E+ PGHTLGH+
Sbjct 61 HVGGVAALKELTGARVLGPANE--KIPARDLALEDGERVEVLGLVFEIFHVPGHTLGHIA 118
Query 124 YFIE-ETGSLFCGDTLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLANAE 182
Y+ ET LFCGDTLFA GCGR+FEG+ QM+HSL RLAALP T+VYCTHEYTL+N
Sbjct 119 YYHPAETPLLFCGDTLFAAGCGRLFEGTPAQMHHSLARLAALPANTRVYCTHEYTLSNLR 178
Query 183 FAVTVEPDNLALKERLKEVQSLRSRHQITLPSTIALELATNPFLRTES------------ 230
FA+ VEPDN AL+ER +E LR R +ITLPS I+LEL+TNPFLR
Sbjct 179 FALAVEPDNAALRERFEEATRLRERDRITLPSEISLELSTNPFLRVSEKSVKKKADQRSG 238
Query 231 ------VEEFAKIRTLKDQF 244
E FA +R KDQF
Sbjct 239 QQNRTPEEVFAVLRAWKDQF 258
>C3K9Q0 Hydroxyacylglutathione hydrolase [Pseudomonas fluorescens
(strain SBW25)]
Length=255
Score = 212 bits (539), Expect = 4e-72
Identities = 114/247 (46%), Positives = 150/247 (61%), Gaps = 23/247 (9%)
Query 17 NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQV-KIAQIWLTHWHKDHIGGVPDLIDGS 75
NYIW+L+D HTQ VVDP +++ V + E++ ++ I +TH H DH+GGV L +
Sbjct 13 NYIWLLQDPHTQRCAVVDPGDAAPVLDWLEQNPGWALSDILVTHHHHDHVGGVEQLKGAT 72
Query 76 HIPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVVYFIEETGSLFCG 135
+ VYGP E KIP L + + ++ PGHTLGH+ ++ +G L CG
Sbjct 73 NAKVYGPANE--KIPARDVALNDNDRITVLGWDFDIYTVPGHTLGHITFY--HSGVLLCG 128
Query 136 DTLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLANAEFAVTVEPDNLALK 195
DTLFA GCGR+FEG+ EQMY SL RLAALP T+VYCTHEYT +N +FA VEPDN +
Sbjct 129 DTLFAAGCGRLFEGTPEQMYTSLERLAALPADTRVYCTHEYTQSNLKFAQAVEPDNADIA 188
Query 196 ERLKEVQSLRSRHQITLPSTIALELATNPFLRT------------------ESVEEFAKI 237
ER++ V+ LR+R +ITLPS +ALE TNPFLRT E FA +
Sbjct 189 ERVESVRQLRARGEITLPSNLALERLTNPFLRTSETSVKQKADERNGRDNRSGAEVFASL 248
Query 238 RTLKDQF 244
R KD+F
Sbjct 249 RAWKDKF 255
>A6V707 Hydroxyacylglutathione hydrolase [Pseudomonas aeruginosa
(strain PA7)]
Length=258
Score = 209 bits (531), Expect = 7e-71
Identities = 120/260 (46%), Positives = 155/260 (60%), Gaps = 24/260 (9%)
Query 5 QIDYIDVKNSLKNYIWILKDSHTQEIIVVDPTESSLVQQYCEKH-QVKIAQIWLTHWHKD 63
QID + N NYIW+L+D+ ++ VVDP ++ V+ + H +++ I +TH H D
Sbjct 3 QIDALPAFND--NYIWLLQDATSRRCAVVDPGDARPVEAWLAAHPDWRLSDILVTHHHHD 60
Query 64 HIGGVPDLIDGSHIPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVV 123
H+GGV L + S V GP E KIP L+ + L E+ PGHTLGH+
Sbjct 61 HVGGVAALKELSGARVLGPANE--KIPARDLALEDGERVEVLGLVFEIFHVPGHTLGHIA 118
Query 124 YF-IEETGSLFCGDTLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLANAE 182
Y+ +T LFCGDTLFA GCGR+FEG+ QM+ SL RLAALP T+VYCTHEYTL+N
Sbjct 119 YYHAAQTPLLFCGDTLFAAGCGRLFEGTPAQMHRSLARLAALPANTRVYCTHEYTLSNLR 178
Query 183 FAVTVEPDNLALKERLKEVQSLRSRHQITLPSTIALELATNPFLRTES------------ 230
FA+ VEP+N AL+ER +E LR R +ITLPS I+LEL+TNPFLR
Sbjct 179 FALAVEPENQALRERFEEATRLRERDRITLPSEISLELSTNPFLRVSENSVKKKADQRSG 238
Query 231 ------VEEFAKIRTLKDQF 244
E FA +R KDQF
Sbjct 239 QQNRTPEEVFAVLRAWKDQF 258
>Q4KBH9 Hydroxyacylglutathione hydrolase [Pseudomonas fluorescens
(strain ATCC BAA-477 / NRRL B-23932 / Pf-5)]
Length=255
Score = 206 bits (524), Expect = 7e-70
Identities = 114/229 (50%), Positives = 145/229 (63%), Gaps = 7/229 (3%)
Query 17 NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKI-AQIWLTHWHKDHIGGVPDLIDGS 75
NYIW+L+D +Q VVDP +++ V + E+H + + I +TH H DH+GGV L S
Sbjct 13 NYIWLLQDHRSQRCAVVDPGDAAPVLAWLEQHPGWVLSDILITHHHHDHVGGVERLKQHS 72
Query 76 HIPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVVYFIEETGSLFCG 135
V+GP E KIP L+ EV A PGHTLGH+ Y+ G LFCG
Sbjct 73 AATVHGPARE--KIPARDIGLEDNQRVSILGWEFEVFAVPGHTLGHIAYY--HHGLLFCG 128
Query 136 DTLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLANAEFAVTVEPDNLALK 195
DTLFA GCGR+FEG+ EQM+HSL RLAALP T +YCTHEYTL+N FA VEP N +
Sbjct 129 DTLFAAGCGRLFEGTPEQMHHSLGRLAALPDDTLIYCTHEYTLSNLRFAQAVEPANPDIA 188
Query 196 ERLKEVQSLRSRHQITLPSTIALELATNPFLRT--ESVEEFAKIRTLKD 242
ERL +V +R + ++TLPST+ALE TNPFLRT SV++ A R +D
Sbjct 189 ERLAKVTQMREQGRMTLPSTLALEKLTNPFLRTGETSVKQKADERNGQD 237
>A4G7G5 Hydroxyacylglutathione hydrolase [Herminiimonas arsenicoxydans]
Length=259
Score = 204 bits (519), Expect = 4e-69
Identities = 106/213 (50%), Positives = 137/213 (64%), Gaps = 6/213 (3%)
Query 17 NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKIAQIWLTHWHKDHIGGVPDLIDGSH 76
NY+WI+ D VVDP +++ + E+HQ+ + I LTH H DH+GGV L+ +
Sbjct 13 NYLWIIHDG--VHAAVVDPGDATPILAALEEHQLSLVAILLTHHHADHVGGVAKLLQHFN 70
Query 77 IPVYGPREELSKIPLITHPLQHEN--HFKFNHLNVEVLATPGHTLGHVVYFIEETGSLFC 134
+PV+ PR++ I ++HPL + H L++ VLA PGHTLGH+ Y E G LFC
Sbjct 71 VPVFAPRKD--PIANVSHPLDDGDTVHIPELDLHLSVLAVPGHTLGHIAYVAAEQGWLFC 128
Query 135 GDTLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLANAEFAVTVEPDNLAL 194
GDTLFA GCGR+FEG+ QM SL +LAALP TKVYC HEYT++N FA+ EPDN AL
Sbjct 129 GDTLFAGGCGRLFEGTPTQMLTSLEKLAALPDDTKVYCAHEYTISNLRFALAAEPDNAAL 188
Query 195 KERLKEVQSLRSRHQITLPSTIALELATNPFLR 227
R K Q+ R T+PSTI LE +TNPFLR
Sbjct 189 AIRFKAEQAKREADIPTVPSTIGLEKSTNPFLR 221
>Q7NG34 Hydroxyacylglutathione hydrolase [Gloeobacter violaceus
(strain ATCC 29082 / PCC 7421)]
Length=252
Score = 202 bits (513), Expect = 3e-68
Identities = 113/246 (46%), Positives = 147/246 (60%), Gaps = 14/246 (6%)
Query 13 NSLK-NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKIAQIWLTHWHKDHIGGVPDL 71
N+LK NY+++L+D + VVDP E+ V + + +K+ I+ TH H DH+GG +L
Sbjct 7 NALKDNYVFVLEDEAARTAAVVDPAEARPVLEALVRLGLKLVAIFNTHHHHDHVGGNREL 66
Query 72 IDG-SHIPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVVYFIEETG 130
++ I VY R + +IP T L+ + F V+ PGHT GH+ Y G
Sbjct 67 LEAYPGIAVYASRRDRGRIPGQTVELEDGDTVAFGCERARVIFVPGHTHGHIAYHFAGCG 126
Query 131 SLFCGDTLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLANAEFAVTVEPD 190
LFCGDTLFA GCGR+FEG+ QM HSL RL LP T+V+C HEYTL N FA T+EPD
Sbjct 127 HLFCGDTLFAGGCGRLFEGTARQMQHSLGRLRELPGETQVWCAHEYTLGNLRFAHTLEPD 186
Query 191 NLALKERLKEVQSLRSRHQITLPSTIALELATNPFLRTES------------VEEFAKIR 238
N L ERL+ V+ LR+R T+PST+A E ATNPFLR ES E FA +R
Sbjct 187 NAELAERLRTVEVLRARKIATVPSTMAAERATNPFLRWESRQLQRAAGAIEPEEVFAHLR 246
Query 239 TLKDQF 244
LKD+F
Sbjct 247 ALKDRF 252
>Q3KE79 Hydroxyacylglutathione hydrolase [Pseudomonas fluorescens
(strain Pf0-1)]
Length=255
Score = 202 bits (513), Expect = 3e-68
Identities = 114/247 (46%), Positives = 146/247 (59%), Gaps = 23/247 (9%)
Query 17 NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKI-AQIWLTHWHKDHIGGVPDLIDGS 75
NYIW+L+D TQ VVDP +++ VQ + + H + I +TH H DH+GGV L +
Sbjct 13 NYIWLLQDHATQRCAVVDPGDAAPVQAWLDAHPGWVLGDILITHHHHDHVGGVETLKKAT 72
Query 76 HIPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVVYFIEETGSLFCG 135
VYGP E IP L+ + + + +V A PGHTLGH+ Y+ G LFCG
Sbjct 73 GATVYGPASE--NIPGRDVALKDNDTVRVLGWDFDVYAVPGHTLGHIAYY--HHGLLFCG 128
Query 136 DTLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLANAEFAVTVEPDNLALK 195
DTLFA GCGR+FEG+ +QM+ SL+RLAALP T VYCTHEYTL+N +FA VEPDN +
Sbjct 129 DTLFAAGCGRLFEGTPQQMHQSLSRLAALPEDTLVYCTHEYTLSNLKFAAAVEPDNRDIA 188
Query 196 ERLKEVQSLRSRHQITLPSTIALELATNPFLRTESV------------------EEFAKI 237
RL++V R +TLPST+ALE TNPFLRT + E FA +
Sbjct 189 ARLEKVTRQRENGVMTLPSTLALEKLTNPFLRTGEILVTQKVDERNGPQNRAPSEVFAAL 248
Query 238 RTLKDQF 244
R KD F
Sbjct 249 RAWKDTF 255
>A4Y6B8 Hydroxyacylglutathione hydrolase [Shewanella putrefaciens
(strain CN-32 / ATCC BAA-453)]
Length=267
Score = 202 bits (513), Expect = 5e-68
Identities = 106/236 (45%), Positives = 156/236 (66%), Gaps = 13/236 (6%)
Query 17 NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKIAQIWLTHWHKDHIGGVPDL----- 71
NYIW+L+ + ++ VVDP ++ +V Y HQ+ +A I LTH H+DH GGV +L
Sbjct 13 NYIWVLQQTPHSQVYVVDPGDAKVVIAYLVSHQLALAGILLTHHHQDHTGGVGELKRYVE 72
Query 72 -IDGSHIPVYGPREE-LSKIPLITHP-LQHENHFKFNHLNVEVLATPGHTLGHVVYFIEE 128
+ VYGP++E ++ + + +P ++ E F + ++VL PGHT GH+ YFIE+
Sbjct 73 QTSSQTLQVYGPQKENIAHVNVPLNPEMRTELTLPFLNAQIQVLNVPGHTAGHIAYFIED 132
Query 129 TGSLFCGDTLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLANAEFAVTVE 188
+LFCGDTLF+ GCGR+FEG+ EQM SL LA LP T+V+C HEYTL+N +FA+TVE
Sbjct 133 --ALFCGDTLFSAGCGRLFEGTAEQMLSSLTLLAKLPANTRVFCAHEYTLSNLKFALTVE 190
Query 189 PDNLALKERLKEVQSLRSRHQITLPSTIALELATNPFLRTESVEEFAKIRTLKDQF 244
P+NL L+ +++ +R+++ T+PS+IALE A NPFLR V E + I ++K F
Sbjct 191 PNNLNLQAYMQKATEMRAQNSATIPSSIALERAINPFLR---VGEQSIIDSIKQHF 243
>Q60BX0 Hydroxyacylglutathione hydrolase [Methylococcus capsulatus
(strain ATCC 33009 / NCIMB 11132 / Bath)]
Length=256
Score = 200 bits (508), Expect = 2e-67
Identities = 106/242 (44%), Positives = 144/242 (60%), Gaps = 14/242 (6%)
Query 17 NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKIAQIWLTHWHKDHIGGVPDLIDGSH 76
NY+++L + + VDP + V + + ++ + TH H DH+GG +L +
Sbjct 13 NYVYLLHEPGSGATAAVDPAVAGPVLEALDARGWRLGHVLNTHHHGDHVGGNLELKAATG 72
Query 77 IPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVVYFIEETGSLFCGD 136
V G + +IP I L+ F+ + +L PGHT GHV ++ E+ +LFCGD
Sbjct 73 CTVVGAAGDRHRIPGIDVALKDGEEFRLGSASARMLDVPGHTSGHVAFWFEDDAALFCGD 132
Query 137 TLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLANAEFAVTVEPDNLALKE 196
TLFA+GCGR+FEGS EQM+ SL RL ALP TKV+C HEYT ANA FAVT+EP N AL+E
Sbjct 133 TLFALGCGRLFEGSAEQMWRSLERLRALPAETKVFCAHEYTQANARFAVTIEPGNAALRE 192
Query 197 RLKEVQSLRSRHQITLPSTIALELATNPFLRTES--------------VEEFAKIRTLKD 242
R++ V++LR T+PS ++ ELATNPFLR ES VE FA+IR KD
Sbjct 193 RVERVEALRREGAATVPSILSEELATNPFLRPESPEIRARLGLPGVPEVEVFAEIRRRKD 252
Query 243 QF 244
F
Sbjct 253 VF 254
>Q5E3G3 Hydroxyacylglutathione hydrolase [Aliivibrio fischeri
(strain ATCC 700601 / ES114)]
Length=252
Score = 184 bits (468), Expect = 2e-61
Identities = 103/245 (42%), Positives = 143/245 (58%), Gaps = 22/245 (9%)
Query 17 NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKIAQIWLTHWHKDHIGGVPDLI-DGS 75
NYIW++ ++ +VVDP +++ V + ++H + I +TH H DHIGGVP+L+
Sbjct 13 NYIWLIHNNDNH-CVVVDPGDATPVLECIKEHDFILDAILITHHHHDHIGGVPELVRQFP 71
Query 76 HIPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVVYFIEETGSLFCG 135
++ V GP E IP +THP+ + + VL PGHT GHV Y +E LFCG
Sbjct 72 NVNVVGPENE--PIPTLTHPVGDGDFVELFDEQFMVLGVPGHTNGHVAYIGDE--KLFCG 127
Query 136 DTLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLANAEFAVTVEPDNLALK 195
D LF+ GCGR+FEG+ EQM++SL ++AALP T+VYC HEYT +N FA+ VEPDN L
Sbjct 128 DALFSAGCGRLFEGTAEQMFNSLQKMAALPDETEVYCAHEYTASNLAFALAVEPDNDYLL 187
Query 196 ERLKEVQSLRSRHQITLPSTIALELATNPFLRTE----------------SVEEFAKIRT 239
++V LR+ + T+PST+ E NPFLRT VE F +R
Sbjct 188 RYREKVLHLRAHGKSTIPSTLQREKLINPFLRTSEANVKKSVASKVQDSTEVEIFTALRR 247
Query 240 LKDQF 244
KD+F
Sbjct 248 WKDEF 252
>P0AC84 Hydroxyacylglutathione hydrolase GloB [Escherichia coli
(strain K12)]
Length=251
Score = 177 bits (449), Expect = 1e-58
Identities = 103/246 (42%), Positives = 146/246 (59%), Gaps = 24/246 (10%)
Query 17 NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKIAQIWLTHWHKDHIGGVPDLIDG-S 75
NYIW+L D ++VDP ++ V + + I+LTH H DH+GGV +L++
Sbjct 12 NYIWVLNDE-AGRCLIVDPGDAEPVLNAIAANNWQPEAIFLTHHHHDHVGGVKELVEKFP 70
Query 76 HIPVYGPREELSKIPLITHPLQH-ENHFKFNHLNVEVLATPGHTLGHVVYFIEETGSLFC 134
I VYGP+E K T ++ E F H V+ATPGHTLGH+ YF + LFC
Sbjct 71 QIVVYGPQETQDKGT--TQVVKDGETAFVLGH-EFSVIATPGHTLGHICYFSKPY--LFC 125
Query 135 GDTLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLANAEFAVTVEPDNLAL 194
GDTLF+ GCGR+FEG+ QMY SL +L+ALP T V C HEYTL+N +FA+++ P +L++
Sbjct 126 GDTLFSGGCGRLFEGTASQMYQSLKKLSALPDDTLVCCAHEYTLSNMKFALSILPHDLSI 185
Query 195 KERLKEVQSLRSRHQITLPSTIALELATNPFLRTESV----------------EEFAKIR 238
+ ++V+ LR+++QITLP + E N FLRTE + E FA +R
Sbjct 186 NDYYRKVKELRAKNQITLPVILKNERQINVFLRTEDIDLINVINEETLLQQPEERFAWLR 245
Query 239 TLKDQF 244
+ KD+F
Sbjct 246 SKKDRF 251
>Q8ZRM2 Hydroxyacylglutathione hydrolase [Salmonella typhimurium
(strain LT2 / SGSC1412 / ATCC 700720)]
Length=251
Score = 166 bits (421), Expect = 2e-54
Identities = 99/247 (40%), Positives = 140/247 (57%), Gaps = 26/247 (11%)
Query 17 NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKIAQIWLTHWHKDHIGGVPDLIDGSH 76
NYIW+L + + ++VDP E++ V + +H+ I+LTH H DH+GGV +L+ H
Sbjct 12 NYIWVLTNDEGR-CVIVDPGEAAPVLKAIAEHKWMPEAIFLTHHHHDHVGGVKELLQ--H 68
Query 77 IP---VYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVVYFIEETGSLF 133
P VYGP E K TH + + + + ATPGHTLGHV YF LF
Sbjct 69 FPQMTVYGPAETQDKGA--THLVGDGDTIRVLGEKFTLFATPGHTLGHVCYFSRPY--LF 124
Query 134 CGDTLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLANAEFAVTVEPDNLA 193
CGDTLF+ GCGR+FEG+ QMY SL ++ +LP T + C HEYTLAN +FA+++ P +
Sbjct 125 CGDTLFSGGCGRLFEGTPSQMYQSLMKINSLPDDTLICCAHEYTLANIKFALSILPHDSF 184
Query 194 LKERLKEVQSLRSRHQITLPSTIALELATNPFLRTESVE----------------EFAKI 237
+ E ++V+ LR + Q+TLP + E N FLRTE ++ FA +
Sbjct 185 INEYYRKVKELRVKKQMTLPVILKNERKINLFLRTEDIDLINEINKETILQQPEARFAWL 244
Query 238 RTLKDQF 244
R+ KD F
Sbjct 245 RSKKDTF 251
>P96981 Hydroxyacylglutathione hydrolase [Rhodobacter capsulatus]
Length=256
Score = 166 bits (419), Expect = 5e-54
Identities = 84/213 (39%), Positives = 125/213 (59%), Gaps = 0/213 (0%)
Query 17 NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKIAQIWLTHWHKDHIGGVPDLIDGSH 76
NY W+ D+ T ++VVD E++ V + + ++ I +TH H DHI GV L +
Sbjct 14 NYAWLWHDTATDTVVVVDVPEAAPVLKVLTDRRWQLHHILITHHHADHIAGVEALAQATG 73
Query 77 IPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVVYFIEETGSLFCGD 136
V G + ++P + HP+ + +V+A GHTLGH+ +++ G LF GD
Sbjct 74 AKVAGAAADAHRLPPLDHPVAPGDVLHLGMEAAQVIAADGHTLGHIAWYLPGAGLLFSGD 133
Query 137 TLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLANAEFAVTVEPDNLALKE 196
+L + GCGR+FEG+ QM+ +L RLAALP T+V HEYT AN FA+++EP N L +
Sbjct 134 SLMSWGCGRLFEGTPAQMFDTLTRLAALPPETRVCSGHEYTAANGRFALSLEPGNGRLHD 193
Query 197 RLKEVQSLRSRHQITLPSTIALELATNPFLRTE 229
R+ V +LR + +LP T+ E ATNPFLR +
Sbjct 194 RMDRVTALRLAGEPSLPVTLGEERATNPFLRAD 226
>Q16775 Hydroxyacylglutathione hydrolase, mitochondrial [Homo
sapiens]
Length=308
Score = 165 bits (418), Expect = 3e-53
Identities = 95/247 (38%), Positives = 137/247 (55%), Gaps = 22/247 (9%)
Query 17 NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKIAQIWLTHWHKDHIGGVPDLID-GS 75
NY++++ D T+E +VDP + V KH VK+ + TH H DH GG L+ S
Sbjct 60 NYMYLVIDDETKEAAIVDPVQPQKVVDAARKHGVKLTTVLTTHHHWDHAGGNEKLVKLES 119
Query 76 HIPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVVYFIEETG----- 130
+ VYG + +I +TH + H + + LNV+ LATP HT GH+ YF+ + G
Sbjct 120 GLKVYGGDD---RIGALTHKITHLSTLQVGSLNVKCLATPCHTSGHICYFVSKPGGSEPP 176
Query 131 SLFCGDTLFAMGCGRVFEGSFEQMYHSLNR-LAALPTTTKVYCTHEYTLANAEFAVTVEP 189
++F GDTLF GCG+ +EG+ ++M +L L LP T+VYC HEYT+ N +FA VEP
Sbjct 177 AVFTGDTLFVAGCGKFYEGTADEMCKALLEVLGRLPPDTRVYCGHEYTINNLKFARHVEP 236
Query 190 DNLALKERLKEVQSLRSRHQITLPSTIALELATNPFLR------------TESVEEFAKI 237
N A++E+L + S + T+PST+A E NPF+R T+ V +
Sbjct 237 GNAAIREKLAWAKEKYSIGEPTVPSTLAEEFTYNPFMRVREKTVQQHAGETDPVTTMRAV 296
Query 238 RTLKDQF 244
R KDQF
Sbjct 297 RREKDQF 303
>O35952 Hydroxyacylglutathione hydrolase, mitochondrial [Rattus
norvegicus]
Length=309
Score = 165 bits (417), Expect = 4e-53
Identities = 96/247 (39%), Positives = 139/247 (56%), Gaps = 22/247 (9%)
Query 17 NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKIAQIWLTHWHKDHIGGVPDLID-GS 75
NY++++ D TQE VVDP + V + +KH+VK+ + TH H DH GG L+
Sbjct 61 NYMYLIIDEDTQEAAVVDPVQPQKVIETVKKHRVKLTTVLTTHHHWDHAGGNEKLVKLEP 120
Query 76 HIPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVVYFIEETGS---- 131
+ VYG + +I +TH + H + + L+V+ L+TP HT GH+ YF+ + GS
Sbjct 121 GLKVYGGDD---RIGALTHKVTHLSTLEVGSLSVKCLSTPCHTSGHICYFVSKPGSSEPS 177
Query 132 -LFCGDTLFAMGCGRVFEGSFEQMYHSLNR-LAALPTTTKVYCTHEYTLANAEFAVTVEP 189
+F GDTLF GCG+ +EG+ ++MY +L L LP TKV C HEYT+ N +FA VEP
Sbjct 178 AVFTGDTLFVAGCGKFYEGTADEMYKALLEVLGRLPPDTKVICGHEYTVNNLKFARHVEP 237
Query 190 DNLALKERLKEVQSLRSRHQITLPSTIALELATNPFLR------------TESVEEFAKI 237
N A++E+L + + + T+PST+A E NPF+R T+ V I
Sbjct 238 GNTAVQEKLAWAKEKNAIGEPTVPSTLAEEFTYNPFMRVKEKTVQQHAGETDPVTTMRAI 297
Query 238 RTLKDQF 244
R KDQF
Sbjct 298 RREKDQF 304
>O24496 Hydroxyacylglutathione hydrolase cytoplasmic [Arabidopsis
thaliana]
Length=258
Score = 161 bits (407), Expect = 3e-52
Identities = 99/253 (39%), Positives = 136/253 (54%), Gaps = 33/253 (13%)
Query 17 NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKIAQIWLTHWHKDHIGG-------VP 69
NY +++ D T + VVDP + V EKHQ KI + TH H DH GG VP
Sbjct 12 NYSYLIIDESTGDAAVVDPVDPEKVIASAEKHQAKIKFVLTTHHHWDHAGGNEKIKQLVP 71
Query 70 DLIDGSHIPVYGPREELSKIPLITHPLQHENHFKFNH-LNVEVLATPGHTLGHVVYFIE- 127
D I VYG L K+ T + + + +N+ L TP HT GH+ Y++
Sbjct 72 D------IKVYGG--SLDKVKGCTDAVDNGDKLTLGQDINILALHTPCHTKGHISYYVNG 123
Query 128 ---ETGSLFCGDTLFAMGCGRVFEGSFEQMYHSLN-RLAALPTTTKVYCTHEYTLANAEF 183
E ++F GDTLF GCG+ FEG+ EQMY SL LAALP T+VYC HEYT+ N EF
Sbjct 124 KEGENPAVFTGDTLFVAGCGKFFEGTAEQMYQSLCVTLAALPKPTQVYCGHEYTVKNLEF 183
Query 184 AVTVEPDNLALKERLKEVQSLRSRHQITLPSTIALELATNPFLRTES------------V 231
A+TVEP+N ++++L + R T+PST+ EL TNPF+R + +
Sbjct 184 ALTVEPNNGKIQQKLAWARQQRQADLPTIPSTLEEELETNPFMRVDKPEIQEKLGCKSPI 243
Query 232 EEFAKIRTLKDQF 244
+ ++R KDQ+
Sbjct 244 DTMREVRNKKDQW 256
>Q9SID3 Hydroxyacylglutathione hydrolase 2, mitochondrial [Arabidopsis
thaliana]
Length=324
Score = 162 bits (410), Expect = 6e-52
Identities = 82/216 (38%), Positives = 129/216 (60%), Gaps = 0/216 (0%)
Query 17 NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKIAQIWLTHWHKDHIGGVPDLIDGSH 76
NY +IL D T + VVDP+E+ + ++ + I TH H DH GG +L D
Sbjct 82 NYAYILHDEDTGTVGVVDPSEAEPIIDSLKRSGRNLTYILNTHHHYDHTGGNLELKDRYG 141
Query 77 IPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVVYFIEETGSLFCGD 136
V G + +IP I L+ + + F V V+ TPGHT GH+ + + ++F GD
Sbjct 142 AKVIGSAMDKDRIPGIDMALKDGDKWMFAGHEVHVMDTPGHTKGHISLYFPGSRAIFTGD 201
Query 137 TLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLANAEFAVTVEPDNLALKE 196
T+F++ CG++FEG+ +QM SL ++ +LP T +YC HEYTL+N++FA+++EP+N L+
Sbjct 202 TMFSLSCGKLFEGTPKQMLASLQKITSLPDDTSIYCGHEYTLSNSKFALSLEPNNEVLQS 261
Query 197 RLKEVQSLRSRHQITLPSTIALELATNPFLRTESVE 232
V LRS+ T+P+T+ +E A NPFLR+ + +
Sbjct 262 YAAHVAELRSKKLPTIPTTVKMEKACNPFLRSSNTD 297
>Q08889 Hydroxyacylglutathione hydrolase [Buchnera aphidicola
subsp. Schizaphis graminum (strain Sg)]
Length=250
Score = 152 bits (384), Expect = 7e-49
Identities = 89/244 (36%), Positives = 137/244 (56%), Gaps = 21/244 (9%)
Query 17 NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKIAQIWLTHWHKDHIGGVPDLIDG-S 75
NY+WIL + + I++DP S + + EK K+ I LTH H DH+GGV ++I
Sbjct 12 NYVWILYNDNCS-CIIIDPGVSEDIIKKIEKKNWKLIAILLTHNHIDHVGGVEEIIRRYP 70
Query 76 HIPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVVYFIEETGSLFCG 135
++ V+GP E +K + ++ + K + V TPGHTLGHV Y+++ +FCG
Sbjct 71 NVTVFGPEE--TKTRNVNKIVKQGDVIKLLKSEIHVFLTPGHTLGHVSYYLKPY--IFCG 126
Query 136 DTLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLANAEFAVTVEPDNLALK 195
DTLF+ GCGRVF+ F MY S+N + +LP T + C+HEYTL+N FA+++ P + +K
Sbjct 127 DTLFSGGCGRVFKNKFFDMYQSINFIKSLPKKTILCCSHEYTLSNLNFAMSILPFDKKIK 186
Query 196 ERLKEVQSLRSRHQITLPSTIALELATNPFLR---------------TESVEEFAKIRTL 240
+ K+++ S+++ +LP ++ E N FLR T S E F +R
Sbjct 187 KYYKKIKKHISQNKTSLPVSLETEKKINIFLRTNEKTIKKAMGLKKDTSSFEVFILLRKE 246
Query 241 KDQF 244
KD F
Sbjct 247 KDDF 250
>Q69ZP3 Probable hydrolase PNKD [Mus musculus]
Length=385
Score = 154 bits (389), Expect = 3e-48
Identities = 90/222 (41%), Positives = 121/222 (55%), Gaps = 8/222 (4%)
Query 17 NYIWILKDSHTQEIIVVDPTESSLVQQYCEKHQVKIAQIWLTHWHKDHIGGVPDLIDGSH 76
NY +++ D+ + VDP++ VQ EK +V + I TH H DH GG DL
Sbjct 130 NYSYLIIDTQAGLAVAVDPSDPRAVQASIEKERVNLVAILCTHKHWDHSGGNRDLSRRHR 189
Query 77 -IPVYGPREELSKIPLITHPLQHENHFKFNHLNVEVLATPGHTLGHVVYFIEET-----G 130
VYG ++ IP +THPL H++ L + LATPGHT GH+VY ++
Sbjct 190 DCRVYGSPQD--GIPYLTHPLCHQDVVSVGRLQIRALATPGHTQGHLVYLLDGEPYKGPS 247
Query 131 SLFCGDTLFAMGCGRVFEGSFEQMYHSLNRLAALPTTTKVYCTHEYTLANAEFAVTVEPD 190
LF GD LF GCGR FEG+ E M SL+ + L T ++ HEY N FA VEP+
Sbjct 248 CLFSGDLLFLSGCGRTFEGTAETMLSSLDTVLDLGDDTLLWPGHEYAEENLGFAGVVEPE 307
Query 191 NLALKERLKEVQSLRSRHQITLPSTIALELATNPFLRTESVE 232
NLA + +++ VQ R + T PST+ E A NPFLRT +E
Sbjct 308 NLARERKMQWVQRQRMERKSTCPSTLGEERAYNPFLRTHCLE 349
Lambda K H a alpha
0.323 0.138 0.422 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 911937
Database: c80497ead7802b24471d0993ca2374ca.SwissProt.fasta
Posted date: May 20, 2024 11:54 PM
Number of letters in database: 5,417
Number of sequences in database: 20
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
