BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: d23d6639aee6042f4d4c9afdfe20f6e3.SwissProt.fasta
           5 sequences; 1,548 total letters



Query= ACIAD2638

Length=338
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

P0ACV3 Lipid A biosynthesis acyltransferase [Shigella flexneri]       67.0    2e-16
P0ACV2 Lipid A biosynthesis palmitoleoyltransferase [Escherichia ...  67.0    2e-16
P44567 Lipid A biosynthesis acyltransferase [Haemophilus influenz...  63.5    3e-15
O06659 Lipid A biosynthesis acyltransferase 2 [Shigella flexneri]     62.4    8e-15
A0QWG5 Phosphatidylinositol mannoside acyltransferase [Mycoliciba...  41.2    6e-08


>P0ACV3 Lipid A biosynthesis acyltransferase [Shigella flexneri]
Length=306

 Score = 67.0 bits (162),  Expect = 2e-16
 Identities = 55/241 (23%), Positives = 110/241 (46%), Gaps = 7/241 (3%)

Query  51   NLKITLPYLNDQQRERIIQNAIRNELTSYMEFFSIWGSSNQKNISRIHHVEGADFFHQAI  110
            NL++  P  + ++RE++I    R+   + +E    W   + + + +   VEG D   +A 
Sbjct  62   NLELCFPQHSAEEREKMIAENFRSLGMALVETGMAWFWPDSR-VRKWFDVEGLDNLKRAQ  120

Query  111  AENKGIVLIVPHFGTWEIMNAWCAQYTDMTILYKPVKDKDADRFVREARSREQAKLVPTD  170
             +N+G++++  HF + E+          M   Y+P  ++  +      R R    ++   
Sbjct  121  MQNRGVMVVGVHFMSLELGGRVMGLCQPMMATYRPHNNQLMEWVQTRGRMRSNKAMI--G  178

Query  171  ESGVRQIFKALKQGGTTVILPDHT-PNVGGEMVDYFGIP-LASSNLSAKLIQKTKAKALF  228
             + +R I  ALK+G      PD      G     +F +  +A++N +  L + + A  L 
Sbjct  179  RNNLRGIVGALKKGEAVWFAPDQDYGRKGSSFAPFFAVENVATTNGTYVLSRLSGAAMLT  238

Query  229  LYAIRNENH-GFDMFIEPMDPAIYQGTDHDGTLVIHHAIEDLIRKYPDHYHWSYKRFKAN  287
            +  +R  ++ G+ +FI P +   Y   ++     ++  IE  I + P+ Y W ++RFK  
Sbjct  239  VTMVRKADYSGYRLFITP-EMEGYPTDENQAAAYMNKIIEKEIMRAPEQYLWIHRRFKTR  297

Query  288  P  288
            P
Sbjct  298  P  298


>P0ACV2 Lipid A biosynthesis palmitoleoyltransferase [Escherichia 
coli (strain K12)]
Length=306

 Score = 67.0 bits (162),  Expect = 2e-16
 Identities = 55/241 (23%), Positives = 110/241 (46%), Gaps = 7/241 (3%)

Query  51   NLKITLPYLNDQQRERIIQNAIRNELTSYMEFFSIWGSSNQKNISRIHHVEGADFFHQAI  110
            NL++  P  + ++RE++I    R+   + +E    W   + + + +   VEG D   +A 
Sbjct  62   NLELCFPQHSAEEREKMIAENFRSLGMALVETGMAWFWPDSR-VRKWFDVEGLDNLKRAQ  120

Query  111  AENKGIVLIVPHFGTWEIMNAWCAQYTDMTILYKPVKDKDADRFVREARSREQAKLVPTD  170
             +N+G++++  HF + E+          M   Y+P  ++  +      R R    ++   
Sbjct  121  MQNRGVMVVGVHFMSLELGGRVMGLCQPMMATYRPHNNQLMEWVQTRGRMRSNKAMI--G  178

Query  171  ESGVRQIFKALKQGGTTVILPDHT-PNVGGEMVDYFGIP-LASSNLSAKLIQKTKAKALF  228
             + +R I  ALK+G      PD      G     +F +  +A++N +  L + + A  L 
Sbjct  179  RNNLRGIVGALKKGEAVWFAPDQDYGRKGSSFAPFFAVENVATTNGTYVLSRLSGAAMLT  238

Query  229  LYAIRNENH-GFDMFIEPMDPAIYQGTDHDGTLVIHHAIEDLIRKYPDHYHWSYKRFKAN  287
            +  +R  ++ G+ +FI P +   Y   ++     ++  IE  I + P+ Y W ++RFK  
Sbjct  239  VTMVRKADYSGYRLFITP-EMEGYPTDENQAAAYMNKIIEKEIMRAPEQYLWIHRRFKTR  297

Query  288  P  288
            P
Sbjct  298  P  298


>P44567 Lipid A biosynthesis acyltransferase [Haemophilus influenzae 
(strain ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=318

 Score = 63.5 bits (153),  Expect = 3e-15
 Identities = 64/263 (24%), Positives = 112/263 (43%), Gaps = 17/263 (6%)

Query  40   KLTKTSRTIQLNLKITLPYLNDQQRERIIQNAIRNELTSYMEFFSIWGSSNQKNISRIHH  99
            K  K     Q NL+   P+  +QQRE++I       +   M         ++K++ +   
Sbjct  64   KAKKQRTRAQTNLQYCFPHWTEQQREQVIDKMFA-VVAQVMFGIGEIAIRSKKHLQKRSE  122

Query  100  VEGADFFHQAIAENKGIVLIVPHFGTWEIMNAWCAQYTD---MTILYKPVKDKDADRFVR  156
              G +   QA AE K I+L+VPH   W I  +    +T    MT +Y P ++   D    
Sbjct  123  FIGLEHIEQAKAEGKNIILMVPH--GWAIDASGIILHTQGMPMTSMYNPHRNPLVDWLWT  180

Query  157  EARSREQAKLVPTDESGVRQIFKALKQGGTTVILPDHTPNVGGE---MVDYFGIPLASSN  213
              R R   K+    ++G++     +++G     LPD   + G E    VD+FG   A+  
Sbjct  181  ITRQRFGGKM-HARQNGIKPFLSHVRKGEMGYYLPDE--DFGAEQSVFVDFFGTYKATLP  237

Query  214  LSAKLIQKTKAKALFLYAIRNENHG-FDMFIEPMDPAIYQGTD-HDGTLVIHHAIEDLIR  271
               K+ + +KA  + ++   N   G ++M I    PA+    D       ++  IE  + 
Sbjct  238  GLNKMAKLSKAVVIPMFPRYNAETGKYEMEIH---PAMNLSDDPEQSARAMNEEIESFVT  294

Query  272  KYPDHYHWSYKRFKANPELDNLY  294
              P+ Y W  +  +   + ++LY
Sbjct  295  PAPEQYVWILQLLRTRKDGEDLY  317


>O06659 Lipid A biosynthesis acyltransferase 2 [Shigella flexneri]
Length=314

 Score = 62.4 bits (150),  Expect = 8e-15
 Identities = 57/249 (23%), Positives = 109/249 (44%), Gaps = 10/249 (4%)

Query  43   KTSRTIQLNLKITLPYLNDQQRERIIQNAIRNELTSYMEFFSIWGSSNQKNISRIHHVEG  102
            K  R   +NL +  P  +D +RE I+ N     L S +    +     +K   R+   +G
Sbjct  59   KARRRATINLSLCFPEKSDTEREIIVDNMFATALQSIVMMAELAIRGPEKFQKRVFW-KG  117

Query  103  ADFFHQAIAENKGIVLIVPHFGTWEI-MNAWCAQYTDMTILYKPVKDKDADRFVREARSR  161
             +   +    N+ ++ +VPH  + +I      AQ   M  ++   ++   D +V  +  R
Sbjct  118  LEILEEIRHNNRNVIFLVPHGWSVDIPAMLLAAQGEKMAAMFHQQRNPVID-YVWNSVRR  176

Query  162  EQAKLVPTDESGVRQIFKALKQGGTTVILP--DHTPNVGGEMVDYFGIPLASSNLSAKLI  219
            +    + + E G++   ++++QG     LP  DH P    E  D+F    A+  +  +L+
Sbjct  177  KFGGRLHSREDGIKPFIQSVRQGYWGYYLPDQDHGPEY-SEFADFFATYKATLPIIGRLM  235

Query  220  QKTKAKALFLYAIRNENHGFDMFIE---PMDPAIYQGTDHDGTLVIHHAIEDLIRKYPDH  276
              ++A  + L+ + +E   F + IE   PMD  I    +      ++  +E L+  +P+ 
Sbjct  236  NISQAMIIPLFPVYDEKKHF-LTIEVRPPMDACIASADNKMIARQMNKTVEILVGSHPEQ  294

Query  277  YHWSYKRFK  285
            Y W  K  K
Sbjct  295  YIWVLKLLK  303


>A0QWG5 Phosphatidylinositol mannoside acyltransferase [Mycolicibacterium 
smegmatis (strain ATCC 700084 / mc(2)155)]
Length=304

 Score = 41.2 bits (95),  Expect = 6e-08
 Identities = 40/147 (27%), Positives = 61/147 (41%), Gaps = 7/147 (5%)

Query  104  DFFHQAIAENKGIVLIVPHFGTWEIMNAWCAQ-YTDMTILYKPVKDKDADRFVREARSRE  162
            D    A+   +G VL +PH G W++   W  Q Y   T + + +K +   R   E R   
Sbjct  108  DHLWSALDAGRGAVLALPHSGNWDMAGVWLVQNYGPFTTVAERLKPESLYRRFVEYRESL  167

Query  163  QAKLVPTDESGVRQIFKALKQGGT----TVILPDHTPNVGGEMVDYFGIPLASSNLSAKL  218
              +++P    G R  F+ L +  T      ++ +      G  VD+FG         AKL
Sbjct  168  GFEVLPL-TGGERPPFEVLAERLTDNRPICLMAERDLTRSGVQVDFFGEATRMPAGPAKL  226

Query  219  IQKTKAKALFLYAIRNENHGFDMFIEP  245
              +T A ALF      E  G+ M + P
Sbjct  227  AIETGA-ALFPVHCWFEGDGWGMRVYP  252



Lambda      K        H        a         alpha
   0.322    0.135    0.398    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 404547


  Database: d23d6639aee6042f4d4c9afdfe20f6e3.SwissProt.fasta
    Posted date:  May 20, 2024  6:56 AM
  Number of letters in database: 1,548
  Number of sequences in database:  5



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40