BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: bdf977f9c5fcee9680d7f85401bff5da.SwissProt.fasta
           15 sequences; 4,578 total letters



Query= ACIAD2727

Length=296
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

P43011 Uncharacterized HTH-type transcriptional regulator HI_1364...  158     4e-50
P76250 HTH-type transcriptional regulator DmlR [Escherichia coli ...  148     4e-46
P67663 HTH-type transcriptional activator AaeR [Escherichia coli ...  146     3e-45
P67664 HTH-type transcriptional activator AaeR [Escherichia coli ...  146     3e-45
P67662 HTH-type transcriptional activator AaeR [Escherichia coli ...  146     3e-45
P52689 Probable HTH-type transcriptional regulator LtrA [Klebsiel...  145     4e-45
P30864 Uncharacterized HTH-type transcriptional regulator YafC [E...  144     1e-44
A0A0H2ZDG9 HTH-type transcriptional repressor PA14_22550 [Pseudom...  140     6e-43
P72131 HTH-type transcriptional regulator PtxR [Pseudomonas aerug...  140     7e-43
P37641 Uncharacterized HTH-type transcriptional regulator YhjC [E...  132     6e-40
P75836 Uncharacterized HTH-type transcriptional regulator YcaN [E...  129     7e-39
P77333 HTH-type transcriptional regulator PgrR [Escherichia coli ...  126     7e-38
P45463 HTH-type transcriptional activator TtdR [Escherichia coli ...  125     2e-37
Q01610 Putative transcriptional regulator [Pseudomonas aeruginosa...  116     6e-34
A5F9F9 Iron-regulated virulence regulatory protein IrgB [Vibrio c...  87.0    3e-23


>P43011 Uncharacterized HTH-type transcriptional regulator HI_1364 
[Haemophilus influenzae (strain ATCC 51907 / DSM 11121 
/ KW20 / Rd)]
Length=288

 Score = 158 bits (399),  Expect = 4e-50
 Identities = 95/281 (34%), Positives = 153/281 (54%), Gaps = 4/281 (1%)

Query  1    MEFLNDMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTE  60
            M+ LN +++F +V +  SF  AA + N+  +  S+ +  LE+ +  RLL RTTRK+  TE
Sbjct  1    MDKLNAISIFCKVIETQSFTLAAKQQNISVAMASKLVSQLEEHLKTRLLQRTTRKIMPTE  60

Query  61   AGQVYFERCKPIVSEALLAHEQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPE  120
            AG +Y++RC+ I+ +   A   + ++ S   G L IS+P DFG++ +AP L  F   +P 
Sbjct  61   AGMMYYQRCQGILLDLDEADSSITQLTSSLQGNLLISVPRDFGLLFIAPNLPTFMAKHPH  120

Query  121  INFEIDLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKLMQFRGQLYASADYLEKNGHPNH  180
            ++ E++   K +DL+ +  D+A+R+G   DS+L+  K+        AS +YLE NG P  
Sbjct  121  LHIEVEFNDKKIDLLSEGYDLALRIGYMEDSSLVSRKIGTTTVHFAASPNYLETNGIPQT  180

Query  181  PSDLVHHQCLSFP---NNLLWKLNHKNETVDVKITGRFMLNSVGMMRKLSILGQGIIFTP  237
            P DL HH  L +    N + W  +  N+T   KI  + + NS   +  ++  G GI   P
Sbjct  181  PDDLEHHNGLLYKNAMNQVNWVGSRINQTQRFKIQSKVVSNSGFALLNMAKAGLGIANLP  240

Query  238  RAIVYDDINKGLLVPILTEWQGDFLPAYAM-TETRLLPAKV  277
            + I+     KG L+ IL E++   L  + +    R LP KV
Sbjct  241  KFILGRAFEKGELIEILPEYKQQKLEIHVVYPNRRHLPIKV  281


>P76250 HTH-type transcriptional regulator DmlR [Escherichia coli 
(strain K12)]
Length=307

 Score = 148 bits (374),  Expect = 4e-46
 Identities = 95/293 (32%), Positives = 160/293 (55%), Gaps = 10/293 (3%)

Query  1    MEFLNDMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTE  60
            +  LND+ +F+ V +   F   A++L +  + +S+RI  LE+ + + LLHRTTR+V +TE
Sbjct  4    LPLLNDLRVFMLVARRAGFAAVAEELGVSPAFVSKRIALLEQTLNVVLLHRTTRRVTITE  63

Query  61   AGQVYFERCKPIVSEALLAHEQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPE  120
             G+  +E  + I+ +     ++L ++   P G+LRI     FG  ++AP L   A+ YP+
Sbjct  64   EGERIYEWAQRILQDVGQMMDELSDVRQVPQGMLRIISSFGFGRQVVAPALLALAKAYPQ  123

Query  121  INFEIDLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKLMQFRGQLYASADYLEKNGHPNH  180
            +    D+  +LVDLV + +D+ IR+G+    NLI  KL      L AS +++ ++G P H
Sbjct  124  LELRFDVEDRLVDLVNEGVDLDIRIGDDIAPNLIARKLATNYRILCASPEFIAQHGAPKH  183

Query  181  PSDLVHHQCLSFPNN----LLWKLNHKNETVDVKITGRFMLNSVGMMRKLSILGQGIIFT  236
             +DL    CL          +W+L +K     +K+TG    N   ++ +  + GQGI   
Sbjct  184  LTDLSALPCLVIKERDHPFGVWQLRNKEGPHAIKVTGPLSSNHGEIVHQWCLDGQGIALR  243

Query  237  PRAIVYDDINKGLLVPILTEWQGDFLPA--YAMTETRL-LPAKVRVFIDFLRE  286
                V ++I  G LV +L E+   + PA  +A+  +RL   AKVR+ ++FLR+
Sbjct  244  SWWDVSENIASGHLVQVLPEY---YQPANVWAVYVSRLATSAKVRITVEFLRQ  293


 Score = 16.9 bits (32),  Expect = 8.6
 Identities = 6/11 (55%), Positives = 7/11 (64%), Gaps = 0/11 (0%)

Query  114  FAELYPEINFE  124
            FAE YP  + E
Sbjct  295  FAEHYPNFSLE  305


>P67663 HTH-type transcriptional activator AaeR [Escherichia coli 
O6:H1 (strain CFT073 / ATCC 700928 / UPEC)]
Length=309

 Score = 146 bits (368),  Expect = 3e-45
 Identities = 95/290 (33%), Positives = 152/290 (52%), Gaps = 4/290 (1%)

Query  1    MEFLNDMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTE  60
            ME L  M++F +V +  SF  AA +L M  S++S+ +  LE E+ ++LL+R+TR + LTE
Sbjct  1    MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTE  60

Query  61   AGQVYFERCKPIVSEALLAHEQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPE  120
            AG++Y++ C+ ++ E    HEQL    + P G LRI         +LA L  +  + YP 
Sbjct  61   AGRIYYQGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPG  120

Query  121  INFEIDLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKLMQFRGQLYASADYLEKNGHPNH  180
            ++  +       DL+   +DV IR+G   DS+L   +L      + A+  YL + G P  
Sbjct  121  LSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGAMPMVVCAAKSYLTQYGIPEK  180

Query  181  PSDLVHHQCLSF---PNNLLWKLNHKNETVDVKITGRFMLNSVGMMRKLSILGQGIIFTP  237
            P+DL  H  L +   P+N    +  +  +  +   GRF+ N    + +    G GI + P
Sbjct  181  PADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVP  240

Query  238  RAIVYDDINKGLLVPILTEWQGDFLPAYAM-TETRLLPAKVRVFIDFLRE  286
               V ++IN+G L  +L  +Q D  P YA+ TE   LP KV+V I+ L +
Sbjct  241  LMWVINEINRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTD  290


>P67664 HTH-type transcriptional activator AaeR [Escherichia coli 
O157:H7]
Length=309

 Score = 146 bits (368),  Expect = 3e-45
 Identities = 95/290 (33%), Positives = 152/290 (52%), Gaps = 4/290 (1%)

Query  1    MEFLNDMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTE  60
            ME L  M++F +V +  SF  AA +L M  S++S+ +  LE E+ ++LL+R+TR + LTE
Sbjct  1    MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTE  60

Query  61   AGQVYFERCKPIVSEALLAHEQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPE  120
            AG++Y++ C+ ++ E    HEQL    + P G LRI         +LA L  +  + YP 
Sbjct  61   AGRIYYQGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPG  120

Query  121  INFEIDLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKLMQFRGQLYASADYLEKNGHPNH  180
            ++  +       DL+   +DV IR+G   DS+L   +L      + A+  YL + G P  
Sbjct  121  LSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGAMPMVVCAAKSYLTQYGIPEK  180

Query  181  PSDLVHHQCLSF---PNNLLWKLNHKNETVDVKITGRFMLNSVGMMRKLSILGQGIIFTP  237
            P+DL  H  L +   P+N    +  +  +  +   GRF+ N    + +    G GI + P
Sbjct  181  PADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVP  240

Query  238  RAIVYDDINKGLLVPILTEWQGDFLPAYAM-TETRLLPAKVRVFIDFLRE  286
               V ++IN+G L  +L  +Q D  P YA+ TE   LP KV+V I+ L +
Sbjct  241  LMWVINEINRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTD  290


>P67662 HTH-type transcriptional activator AaeR [Escherichia coli 
(strain K12)]
Length=309

 Score = 146 bits (368),  Expect = 3e-45
 Identities = 95/290 (33%), Positives = 152/290 (52%), Gaps = 4/290 (1%)

Query  1    MEFLNDMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTE  60
            ME L  M++F +V +  SF  AA +L M  S++S+ +  LE E+ ++LL+R+TR + LTE
Sbjct  1    MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTE  60

Query  61   AGQVYFERCKPIVSEALLAHEQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPE  120
            AG++Y++ C+ ++ E    HEQL    + P G LRI         +LA L  +  + YP 
Sbjct  61   AGRIYYQGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPG  120

Query  121  INFEIDLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKLMQFRGQLYASADYLEKNGHPNH  180
            ++  +       DL+   +DV IR+G   DS+L   +L      + A+  YL + G P  
Sbjct  121  LSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGAMPMVVCAAKSYLTQYGIPEK  180

Query  181  PSDLVHHQCLSF---PNNLLWKLNHKNETVDVKITGRFMLNSVGMMRKLSILGQGIIFTP  237
            P+DL  H  L +   P+N    +  +  +  +   GRF+ N    + +    G GI + P
Sbjct  181  PADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVP  240

Query  238  RAIVYDDINKGLLVPILTEWQGDFLPAYAM-TETRLLPAKVRVFIDFLRE  286
               V ++IN+G L  +L  +Q D  P YA+ TE   LP KV+V I+ L +
Sbjct  241  LMWVINEINRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTD  290


>P52689 Probable HTH-type transcriptional regulator LtrA [Klebsiella 
pneumoniae]
Length=309

 Score = 145 bits (367),  Expect = 4e-45
 Identities = 87/295 (29%), Positives = 150/295 (51%), Gaps = 11/295 (4%)

Query  1    MEFLNDMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTE  60
            +  L D+ALFV++    SF   A +  +  S +SR +  LE+E+G +LL RTTRK+ L++
Sbjct  3    LNLLPDLALFVQIVDQGSFSAVARQNGITPSAVSRSVSRLEREMGCKLLQRTTRKLRLSD  62

Query  61   AGQVYFERCKPIVSEALLAHEQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPE  120
            AG+  ++  + ++  A  A +  G   +   G L +S+P   G  ++ PL+  F   YP+
Sbjct  63   AGETIYQHAQQMLEAARQAMDSAGSRQTVAQGKLTLSVPKAVGRFVIHPLMMAFFHRYPQ  122

Query  121  INFEIDLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKLMQFRGQLYASADYLEKNGHPNH  180
            ++  + L  + +D +   ID+A+R+ + P   L G  LM  R  + A+  YL+++G P  
Sbjct  123  VDVCLRLEDRPLDFIDDGIDLALRITDTPSPGLHGKPLMPIRHVICATEAYLQQHGTPYT  182

Query  181  PSDLVHHQCLSF---PNNLLWKLNHKNETVDVKITGRFMLNSVGMMRKLSILGQGIIFTP  237
            P DL  H C+S    P +  WK   + +T  V+  GR+  N   +         GI   P
Sbjct  183  PQDLRAHSCISLGETPADARWKFRREGKTETVQTYGRYAANHTAVRLDAVRQHLGIGSLP  242

Query  238  RAIVYDDINKGLLVPILTEWQGDFLPAYA------MTETRLLPAKVRVFIDFLRE  286
                 + +  G +V +L EW  +F+ +Y+          + +PA++R  ID+L E
Sbjct  243  LFTAREALANGDIVQVLPEW--EFISSYSGDLWLLWAGDKHMPARMRAMIDYLSE  295


>P30864 Uncharacterized HTH-type transcriptional regulator YafC 
[Escherichia coli (strain K12)]
Length=304

 Score = 144 bits (364),  Expect = 1e-44
 Identities = 92/289 (32%), Positives = 152/289 (53%), Gaps = 12/289 (4%)

Query  6    DMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTEAGQVY  65
            ++A+FV V +  SF +AA++L   +S +SR +  LE ++G+ LL+RTTR++ LTE G+ Y
Sbjct  7    ELAIFVSVVESGSFSRAAEQLGQANSAVSRAVKKLEMKLGVSLLNRTTRQLSLTEEGERY  66

Query  66   FERCKPIVSEALLAHEQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPEINFEI  125
            F R + I+ E   A  ++ E  + P GLLRI       +  L PL+  F E YPE+   +
Sbjct  67   FRRVQSILQEMAAAESEIMETRNTPRGLLRIDAATPVVLHFLMPLIKPFRERYPEVTLSL  126

Query  126  DLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKLMQFRGQLYASADYLEKNGHPNHPSDLV  185
              +  +++L+++ +DVAIR G   DS+L    L     ++ AS DY+ + G P    DL 
Sbjct  127  VSSETIINLIERKVDVAIRAGTLTDSSLRARPLFNSYRKIIASPDYISRYGKPETIDDLK  186

Query  186  HHQCLSF--PNNL-LWKLNHKNETVDVKITGRFMLNSVGMMRKLSILGQGIIFTPRAIVY  242
             H CL F  P +L  W +   +  +  ++      NS   +++L + G GI      ++ 
Sbjct  187  QHICLGFTEPASLNTWPIARSDGQLH-EVKYGLSSNSGETLKQLCLSGNGIACLSDYMID  245

Query  243  DDINKGLLVPILTEWQGDFLP-----AYAMTETRLLPAKVRVFIDFLRE  286
             +I +G LV ++ +     LP     +      R +  ++R FIDFL E
Sbjct  246  KEIARGELVELMAD---KVLPVEMPFSAVYYSDRAVSTRIRAFIDFLSE  291


>A0A0H2ZDG9 HTH-type transcriptional repressor PA14_22550 [Pseudomonas 
aeruginosa (strain UCBPP-PA14)]
Length=317

 Score = 140 bits (353),  Expect = 6e-43
 Identities = 89/292 (30%), Positives = 145/292 (50%), Gaps = 6/292 (2%)

Query  1    MEFLNDMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTE  60
            M+ L  MA FV+V    SF +AAD L +P + +S+R+  LEK +G+RLL+RTTR + LT 
Sbjct  1    MDKLTAMATFVKVVDAGSFTRAADALGLPKARVSQRVSDLEKHLGVRLLNRTTRALSLTH  60

Query  61   AGQVYFERCKPIVSEALLAHEQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPE  120
             G  YF++C+ ++ +       L    + P G LR+   +     ++AP L +F   YP 
Sbjct  61   DGSAYFDKCQVLLQQIDELEATLRGGTATPIGRLRVDSLITIARWVIAPRLHDFQARYPR  120

Query  121  INFEIDLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKLMQFRGQLYASADYLEKNGHPNH  180
            I   +  + ++ +L++  ID  IR G   DS++I   L   +  LYAS +YL   G  + 
Sbjct  121  IQLRLSSSDRISNLLEDGIDCTIRGGALKDSSMIARHLCDIQMGLYASPEYLASIGGVDS  180

Query  181  PSDLVHHQCLSF-----PNNLLWKLNHKNETVDVKITGRFMLNSVGMMRKLSILGQGIIF  235
            P+DL   + LS+      N  +W+L    E   V+       +   +     + G GI  
Sbjct  181  PNDLSQFRRLSWFSGRERNPFMWELESGPERFVVQSGDGMQFDEPDVAISACMAGSGICP  240

Query  236  TPRAIVYDDINKGLLVPILTEWQGDFLPAYAM-TETRLLPAKVRVFIDFLRE  286
                 V   +  G LVP+L +W     P + +   +R L  +VR F++++ E
Sbjct  241  GAPFAVAGFVRAGKLVPVLPQWHFSAAPVHVIYPGSRHLSVRVRCFVNWVME  292


>P72131 HTH-type transcriptional regulator PtxR [Pseudomonas aeruginosa 
(strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 
14847 / LMG 12228 / 1C / PRS 101 / PAO1)]
Length=312

 Score = 140 bits (352),  Expect = 7e-43
 Identities = 96/293 (33%), Positives = 148/293 (51%), Gaps = 12/293 (4%)

Query  4    LNDMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTEAGQ  63
            LN +  FV V +  SF  AA+ L +  S LS ++  LE ++G++LL RTTR++ LT+ G+
Sbjct  13   LNHLYAFVAVAEHNSFTAAAEALGLSKSLLSEQLRRLEADLGIQLLTRTTRRMTLTDRGE  72

Query  64   VYFERCKPIVSEALLAHEQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPEINF  123
            + F   + ++ E   A   + ++  +PSG LRI+ P DF    ++ +   F   +P++  
Sbjct  73   LLFGVAQRMLGELDGALSDVRDLQGEPSGRLRITAPQDFVKWHISSVSAAFIRQFPKVQV  132

Query  124  EIDLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKLMQFRGQLYASADYLEKNGHPNHPSD  183
            E+    +  DLV Q ID+A+R+G P DS L   KL  F+    A+  YL        P D
Sbjct  133  EMLADDQFSDLVGQRIDLAVRIGWPRDSGLHASKLCDFQQVAVATPGYLAGLPPVLQPHD  192

Query  184  L-----VHHQCLSFPNNLLWKLNHKNETVDVKITGRFMLNSVGMMRKLSILGQGIIFTPR  238
            L     + H  LS P    W    + E   V+  GR + N+   + +L + G G+   P 
Sbjct  193  LARCEWIGHTRLSTP--WTWTFERQRERATVQTRGRLLANNTLAVYRLVLDGAGVSVLPS  250

Query  239  AIVYDDINKGLLVPILTEW---QGDFLPAYAMTETRLLPAKVRVFIDFLREKL  288
             +V  +I +G LV +L  W   QG     Y     R +P +VR FI+ LRE L
Sbjct  251  FLVAREIARGRLVRLLPGWRLPQGGIYALY--PSARYMPVRVRAFIESLREHL  301


>P37641 Uncharacterized HTH-type transcriptional regulator YhjC 
[Escherichia coli (strain K12)]
Length=299

 Score = 132 bits (331),  Expect = 6e-40
 Identities = 88/290 (30%), Positives = 146/290 (50%), Gaps = 6/290 (2%)

Query  1    MEFLNDMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTE  60
            M+ ++ M LF++V ++ SF +AAD   +P  ++SR+I  LE ++G +LL RTTR+V+LT 
Sbjct  1    MDKIHAMQLFIKVAELESFSRAADFFALPKGSVSRQIQALEHQLGTQLLQRTTRRVKLTP  60

Query  61   AGQVYFERCKPIVSEALLAHEQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPE  120
             G  Y++R K ++S          +  +  SG LRI +P      +L P L+EF  L+P 
Sbjct  61   EGMTYYQRAKDVLSNLSELDGLFQQDATSISGKLRIDIPPGIAKSLLLPRLSEFLYLHPG  120

Query  121  INFEIDLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKLMQFRGQLYASADYLEKNGHPNH  180
            I  E+    + VD++    D  IR G  P+  +I   L +      AS  YL + G+P  
Sbjct  121  IELELSSHDRPVDILHDGFDCVIRTGALPEDGVIARPLGKLTMVNCASPHYLTRFGYPQS  180

Query  181  PSDLVHHQCLSFPNNL-LWKLNHKNETVD----VKITGRFMLNSVGMMRKLSILGQGIIF  235
            P DL  H  + +  +L +  L  +  +V+     K  G   +NS        + G GII 
Sbjct  181  PDDLTSHAIVRYTPHLGVHPLGFEVASVNGVQWFKSGGMLTVNSSENYLTAGLAGLGIIQ  240

Query  236  TPRAIVYDDINKGLLVPILTEWQGDFLP-AYAMTETRLLPAKVRVFIDFL  284
             PR  V + +  G L+ +L  ++ + L  +    + R L  +V +F+ +L
Sbjct  241  IPRIAVREALRAGRLIEVLPGYRAEPLSLSLVYPQRRELSRRVNLFMQWL  290


>P75836 Uncharacterized HTH-type transcriptional regulator YcaN 
[Escherichia coli (strain K12)]
Length=302

 Score = 129 bits (324),  Expect = 7e-39
 Identities = 80/287 (28%), Positives = 147/287 (51%), Gaps = 7/287 (2%)

Query  4    LNDMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTEAGQ  63
            ++D A F  V +  SFR A D+L + SS +S  I  LE+ + +RL +RTTR V LTEAG 
Sbjct  5    MSDFATFFAVARNQSFRAAGDELGLSSSAISHSIKTLEQRLKIRLFNRTTRSVSLTEAGS  64

Query  64   VYFERCKPIVSEALLAHEQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPEINF  123
              +ER +P   E  +  +++ +    P+G L+I+       + L  LL  F   YP+I  
Sbjct  65   NLYERLRPAFDEIQIMLDEMNDFRLTPTGTLKINAARVAARIFLMSLLVGFTREYPDIKV  124

Query  124  EIDLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKL-MQFRGQLYASADYLEKNGHPNHPS  182
            E+     LVD+V+Q  D  +R+    + ++I   +    +  + A+ +Y  + G P HP 
Sbjct  125  ELTTDDSLVDIVQQGFDAGVRLSCIVEKDMISVAIGPPVKLCVAATPEYFARYGKPRHPH  184

Query  183  DLVHHQCLSF--PNNLLWKLNHKNETVDVKITGRFMLNSVGMMRKLSILGQGIIFTPRAI  240
            DL++HQC+ F  P+   +      E +++ + G  +L+ V    +  ++G GI +     
Sbjct  185  DLLNHQCVVFRYPSGKPFHWQFAKE-LEIAVAGNIILDDVDAELEAVLMGAGIGYLLYEQ  243

Query  241  VYDDINKGLLVPILTEWQGDFLPAYAM--TETRLLPAKVRVFIDFLR  285
            + + ++ G L  +L +W  +  P + +     + +   +R F+D+++
Sbjct  244  IKEYLDTGRLECVLEDWSTE-RPGFQIYYPNRQYMSCGLRAFLDYVK  289


>P77333 HTH-type transcriptional regulator PgrR [Escherichia coli 
(strain K12)]
Length=299

 Score = 126 bits (317),  Expect = 7e-38
 Identities = 86/294 (29%), Positives = 149/294 (51%), Gaps = 9/294 (3%)

Query  2    EFLNDMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTEA  61
            E + D+  FV V +  SF +AA +L+M  S LS+ +  +E+ +GLRLL RTTR V  TEA
Sbjct  4    EEIADLMAFVVVAEERSFTRAAARLSMAQSALSQIVRRIEERLGLRLLTRTTRSVVPTEA  63

Query  62   GQVYFERCKPIVSEALLAHEQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPEI  121
            G+       P++ +   A   L ++ ++PSG +RI+        IL P +  F + +PEI
Sbjct  64   GEHLLSVLGPMLHDIDSAMASLSDLQNRPSGTIRITTVEHAAKTILLPAMRTFLKSHPEI  123

Query  122  NFEIDLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKL-MQFRGQLYASADYLEKNGHPNH  180
            + ++ +   L D+V +  D  +R+G   D ++I  ++       +  S DY  +   P  
Sbjct  124  DIQLTIDYGLTDVVSERFDAGVRLGGEMDKDMIAIRIGPDIPMAIVGSPDYFSRRSVPTS  183

Query  181  PSDLVHHQCLS--FPNN---LLWKLNHKNETVDVKITGRFMLNSVGMMRKLSILGQGIIF  235
             S L+ HQ ++   P +     W+L      V V++ G+ +LN++ ++   +I G G+ +
Sbjct  184  VSQLIDHQAINLYLPTSGTANRWRLIRGGREVRVRMEGQLLLNTIDLIIDAAIDGHGLAY  243

Query  236  TPRAIVYDDINKGLLVPILTEWQGDFLPAYAM--TETRLLPAKVRVFIDFLREK  287
             P   V   I +  L+ +L ++  D LP Y +     R   +   +FID L+ K
Sbjct  244  LPYDQVERAIKEKKLIRVLDKFTPD-LPGYHLYYPHRRHAGSAFSLFIDRLKYK  296


>P45463 HTH-type transcriptional activator TtdR [Escherichia coli 
(strain K12)]
Length=310

 Score = 125 bits (315),  Expect = 2e-37
 Identities = 82/283 (29%), Positives = 140/283 (49%), Gaps = 4/283 (1%)

Query  6    DMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTEAGQVY  65
            D+ + VE+    SF  AA  L    + +++RI  LE  +   LL+R+ R V LTE+GQ  
Sbjct  10   DLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQILENTLATTLLNRSARGVALTESGQRC  69

Query  66   FERCKPIVSEALLAHEQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPEINFEI  125
            +E    I+++     + + ++ ++P G++RI     FG   +AP +TE    YPE+    
Sbjct  70   YEHALEILTQYQRLVDDVTQIKTRPEGMIRIGCSFGFGRSHIAPAITELMRNYPELQVHF  129

Query  126  DLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKLMQFRGQLYASADYLEKNGHPNHPSDLV  185
            +L  + +DLV+ NID+ IR+ +      I H L + +  L A+ +YL+K   P    +L 
Sbjct  130  ELFDRQIDLVQDNIDLDIRINDEIPDYYIAHLLTKNKRILCAAPEYLQKYPQPQSLQELS  189

Query  186  HHQCLSFP----NNLLWKLNHKNETVDVKITGRFMLNSVGMMRKLSILGQGIIFTPRAIV  241
             H CL        + +W+L +  E   VK++G    NS  ++ + ++ G+GI+      V
Sbjct  190  RHDCLVTKERDMTHGIWELGNGQEKKSVKVSGHLSSNSGEIVLQWALEGKGIMLRSEWDV  249

Query  242  YDDINKGLLVPILTEWQGDFLPAYAMTETRLLPAKVRVFIDFL  284
               +  G LV +L E+           E      K+RV ++FL
Sbjct  250  LPFLESGKLVQVLPEYAQSANIWAVYREPLYRSMKLRVCVEFL  292


>Q01610 Putative transcriptional regulator [Pseudomonas aeruginosa 
(strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 
/ LMG 12228 / 1C / PRS 101 / PAO1)]
Length=306

 Score = 116 bits (290),  Expect = 6e-34
 Identities = 83/289 (29%), Positives = 130/289 (45%), Gaps = 7/289 (2%)

Query  4    LNDMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTEAGQ  63
            LND+  FV V +  +F +AA +L +  S LS+ I  LE  + +RLL RTTR V  T AG+
Sbjct  6    LNDLLSFVAVAREGTFTRAAAQLGVTQSALSQSISGLEARLQIRLLTRTTRSVSPTAAGE  65

Query  64   VYFERCKPIVSEALLAHEQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPEINF  123
                       E     ++L  +  KPSG +RI+        +L P LT     YP+I  
Sbjct  66   RLLNAIGNRFDEIEAELDELSALRDKPSGTVRITCGDHIQRTLLLPRLTPLLLEYPDIKV  125

Query  124  EIDLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKL-MQFRGQLYASADYLEKNGHPNHPS  182
            E D+     D+V    D  +R+G+  D ++I   +    R  + A+  Y   +  P  P 
Sbjct  126  EFDINYGFRDIVADRFDAGVRLGDTIDKDMIAVPIGPPVRMAVVAAPAYFAAHPKPRSPR  185

Query  183  DLVHHQCLSFPNN-----LLWKLNHKNETVDVKITGRFMLNSVGMMRKLSILGQGIIFTP  237
            DLV H C++           W    K+  V+V++ G+ + N+   +   ++ G GI + P
Sbjct  186  DLVDHNCINMRMQSGGGLYAWDFQRKDRHVNVRVDGQLIFNTSPNIVDAALAGLGIAWLP  245

Query  238  RAIVYDDINKGLLVPILTEWQGDFLPAYAMTETRLLPAKV-RVFIDFLR  285
                   I +G L+ +L  W   F   Y     R  P+    + +D LR
Sbjct  246  EEEFAPHIEEGRLLRVLENWCPLFPGYYLYYPNRRQPSPAFSLVVDALR  294


>A5F9F9 Iron-regulated virulence regulatory protein IrgB [Vibrio 
cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 
395 / O395)]
Length=298

 Score = 87.0 bits (214),  Expect = 3e-23
 Identities = 76/292 (26%), Positives = 132/292 (45%), Gaps = 7/292 (2%)

Query  1    MEFLNDMALFVEVCKVMSFRKAADKLNMPSSTLSRRIGHLEKEIGLRLLHRTTRKVELTE  60
            M+ L+ +  F  +C+  S   AA  L  P STLSRR+  LE+++G  LL R   ++ LT+
Sbjct  1    MQDLSAVKAFHALCQHKSLTAAAKALEQPKSTLSRRLAQLEEDLGQSLLMRQGNRLTLTK  60

Query  61   AGQVYFERCKPIVSEALLAHEQLGEMLSKPSGLLRISLPVDFGVMILAPLLTEFAELYPE  120
            AG+V+    + ++  A  + E L E+ ++ +G L + +  +     L+ +L EF + +  
Sbjct  61   AGEVFAVYSEQLLELANKSQEALQELNNQVTGELTLVVHPNLIRGWLSQVLDEFMQQHST  120

Query  121  INFEIDLTPKLVDLVKQNIDVAIRMGNPPDSNLIGHKLMQFRGQLYASADYLEKNGHPNH  180
            +   +    +  D V +  D+ I + +         +L  +R   YAS  YL     P H
Sbjct  121  LKIRLLSQFQHSDEVFEP-DLIIWIEHAAPMGYRKERLGYWRYATYASPKYLAHRDKPTH  179

Query  181  PSDLVHHQCLSFPNNLLWKLN-HKNETVDVK---ITGRFMLNSVGMMRKLSILGQGIIFT  236
            P +L+HH  + F      +L  H  E        +  R   +++ M       G+GI   
Sbjct  180  PRELIHHPWIDFIACRRAELELHHPEFGSYSLPALESRLQSDNLAMQADAIAKGRGIGLL  239

Query  237  PR--AIVYDDINKGLLVPILTEWQGDFLPAYAMTETRLLPAKVRVFIDFLRE  286
            P   A  ++  + G L+P +  WQ               P ++R+FID LR+
Sbjct  240  PTWFANGFETAHPGSLIPCVNGWQSQPTEINCFYPLGRHPLRLRLFIDALRQ  291



Lambda      K        H        a         alpha
   0.325    0.141    0.419    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 979653


  Database: bdf977f9c5fcee9680d7f85401bff5da.SwissProt.fasta
    Posted date:  May 20, 2024  4:38 PM
  Number of letters in database: 4,578
  Number of sequences in database:  15



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40