BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 50e96fae3b6f62275631f6a103efc47c.SwissProt.fasta
14 sequences; 6,087 total letters
Query= ACIAD2776
Length=396
Score E
Sequences producing significant alignments: (Bits) Value
P45744 Isochorismate synthase DhbC [Bacillus subtilis (strain 168)] 262 1e-87
P0AEJ3 Isochorismate synthase EntC [Escherichia coli O157:H7] 234 9e-77
P0AEJ2 Isochorismate synthase EntC [Escherichia coli (strain K12)] 234 9e-77
O07898 Vibriobactin-specific isochorismate synthase [Vibrio chole... 232 4e-76
P23300 Putative isochorismate synthase [Aeromonas hydrophila] 229 5e-75
P9WFW9 Putative isochorismate synthase MenF [Mycobacterium tuberc... 180 3e-56
P9WFW8 Putative isochorismate synthase MenF [Mycobacterium tuberc... 180 3e-56
P23973 Isochorismate synthase MenF [Bacillus subtilis (strain 168)] 149 8e-44
Q9CPI5 Isochorismate synthase MenF [Pasteurella multocida (strain... 137 1e-39
Q51508 Salicylate biosynthesis isochorismate synthase [Pseudomona... 136 5e-39
Q9ZPC0 Isochorismate synthase, chloroplastic [Catharanthus roseus] 136 1e-38
Q06128 Anthranilate synthase component 1 [Saccharolobus solfatari... 131 1e-37
Q9M9V6 Isochorismate synthase 2, chloroplastic [Arabidopsis thali... 129 5e-36
P38051 Isochorismate synthase MenF [Escherichia coli (strain K12)] 127 6e-36
>P45744 Isochorismate synthase DhbC [Bacillus subtilis (strain
168)]
Length=398
Score = 262 bits (669), Expect = 1e-87
Identities = 149/369 (40%), Positives = 218/369 (59%), Gaps = 10/369 (3%)
Query 31 FLTKDYR-LLASDLAEVVKLA--ACDYEKLSQTITDSFQKLKKDPNANPILVGAIPFDTT 87
FL +R LLA + E+V A E LS I ++ ++ K+ + P++VGA+PFD
Sbjct 25 FLASPHRVLLAKGICEIVPEADGQNQMETLSGRIAEALRQAKQSGQSRPLVVGAVPFDQV 84
Query 88 QASSLNIYRNHRKQRQLVISSKITHSPLSISNQ-KPLIKQKDFAHAIDIAIDQFRCDQLE 146
+A+ L + R L + + KP+ + +D+ + ++ + + L
Sbjct 85 KAARLVVPEEVRWSGPLQFDHEEKEQQAGHTYHIKPVPEPEDYKNGVEQGLARIADGTLS 144
Query 147 KVVLSQAVDFELSQSQNPFDLVDTLAKENPHAFSFAIPVEDNAY------LLGASPELLI 200
K+VLS+++ + +L+ LA+ N H ++FA V LLGASPELL+
Sbjct 145 KIVLSRSLHLTSPEPIQTDELLRHLAQHNSHGYTFAADVSSQEETSPRRTLLGASPELLV 204
Query 201 SKNDLTVRSNPLAGSRPLSEDENINQSRIHELYASEKDLNEHQIVVDSVLENLKPFCQKL 260
S+ V SNPLAGSRP S D +Q R EL +S KDL+EH +V D+V L+PFC+ L
Sbjct 205 SRMGTQVVSNPLAGSRPRSNDPVEDQRRAAELLSSAKDLHEHAVVADAVAAALRPFCRTL 264
Query 261 KVLEKPEILKTATMLHLSTVFDGQLKKQSDNALQLALALHPTPAICGSPTEPAKQFILEH 320
+V EKP ++KT TM HLS+V G+L S AL+LA ALHPTPA+CG+PT+ A++ IL
Sbjct 265 EVPEKPSLIKTETMWHLSSVIKGELSDPSVTALELAAALHPTPAVCGTPTDLAREAILSI 324
Query 321 EGYDRHYFAGLVGWMDAQGNGEWAVTIRCGLLNDKKIRLYAGAGIVMGSQAELEWSETEV 380
E +DR +F G+VGW D G+GEW VTIRC ++ +RLYAGAG+V GS+ E E ET
Sbjct 325 EPFDRGFFTGMVGWCDDAGDGEWIVTIRCAEAEERSLRLYAGAGVVAGSKPEDELQETSA 384
Query 381 KMQTLLKTL 389
K +T+L+ +
Sbjct 385 KFRTMLRAM 393
>P0AEJ3 Isochorismate synthase EntC [Escherichia coli O157:H7]
Length=391
Score = 234 bits (596), Expect = 9e-77
Identities = 132/332 (40%), Positives = 196/332 (59%), Gaps = 5/332 (2%)
Query 59 QTITDSFQKLKKDPNANPILVGAIPFDTTQASSLNI---YRNHRKQRQLVISSKITHSP- 114
Q + F K NP++VGAIPFD Q SSL I +++ +Q + + + T S
Sbjct 55 QKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARRFTRSQS 114
Query 115 LSISNQKPLIKQKDFAHAIDIAIDQFRCDQLEKVVLSQAVDFELSQSQNPFDLVDTLAKE 174
L++ ++ + +Q F + A Q++KVVLS+ +D + + L++ L +
Sbjct 115 LNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQ 174
Query 175 NPHAFSFAIPVEDNAYLLGASPELLISKNDLTVRSNPLAGSRPLSEDENINQSRIHELYA 234
NP +++F +P+ D LLGASPELL+ K+ S PLAGS DE +++ + L A
Sbjct 175 NPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLA 234
Query 235 SEKDLNEHQIVVDSVLENLKPFCQKLKVLEKPEILKTATMLHLSTVFDGQLKKQSDNALQ 294
SEKD +EH++V ++ E L+ +L V P+++ T T+ HL+T F+G+ Q +NAL
Sbjct 235 SEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQ-ENALT 293
Query 295 LALALHPTPAICGSPTEPAKQFILEHEGYDRHYFAGLVGWMDAQGNGEWAVTIRCGLLND 354
LA LHPTPA+ G P + A Q I E E +DR F G+VGW D++GNGEW VTIRC L +
Sbjct 294 LACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRE 353
Query 355 KKIRLYAGAGIVMGSQAELEWSETEVKMQTLL 386
++RL+AGAGIV S EW ET VK+ T+L
Sbjct 354 NQVRLFAGAGIVPASSPLGEWRETGVKLSTML 385
>P0AEJ2 Isochorismate synthase EntC [Escherichia coli (strain
K12)]
Length=391
Score = 234 bits (596), Expect = 9e-77
Identities = 132/332 (40%), Positives = 196/332 (59%), Gaps = 5/332 (2%)
Query 59 QTITDSFQKLKKDPNANPILVGAIPFDTTQASSLNI---YRNHRKQRQLVISSKITHSP- 114
Q + F K NP++VGAIPFD Q SSL I +++ +Q + + + T S
Sbjct 55 QKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEKQASARRFTRSQS 114
Query 115 LSISNQKPLIKQKDFAHAIDIAIDQFRCDQLEKVVLSQAVDFELSQSQNPFDLVDTLAKE 174
L++ ++ + +Q F + A Q++KVVLS+ +D + + L++ L +
Sbjct 115 LNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDAAIDSGVLLERLIAQ 174
Query 175 NPHAFSFAIPVEDNAYLLGASPELLISKNDLTVRSNPLAGSRPLSEDENINQSRIHELYA 234
NP +++F +P+ D LLGASPELL+ K+ S PLAGS DE +++ + L A
Sbjct 175 NPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLA 234
Query 235 SEKDLNEHQIVVDSVLENLKPFCQKLKVLEKPEILKTATMLHLSTVFDGQLKKQSDNALQ 294
SEKD +EH++V ++ E L+ +L V P+++ T T+ HL+T F+G+ Q +NAL
Sbjct 235 SEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQ-ENALT 293
Query 295 LALALHPTPAICGSPTEPAKQFILEHEGYDRHYFAGLVGWMDAQGNGEWAVTIRCGLLND 354
LA LHPTPA+ G P + A Q I E E +DR F G+VGW D++GNGEW VTIRC L +
Sbjct 294 LACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRE 353
Query 355 KKIRLYAGAGIVMGSQAELEWSETEVKMQTLL 386
++RL+AGAGIV S EW ET VK+ T+L
Sbjct 354 NQVRLFAGAGIVPASSPLGEWRETGVKLSTML 385
>O07898 Vibriobactin-specific isochorismate synthase [Vibrio cholerae
serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)]
Length=395
Score = 232 bits (592), Expect = 4e-76
Identities = 137/374 (37%), Positives = 203/374 (54%), Gaps = 10/374 (3%)
Query 17 DHAIELNINLESSCFLTKDYRLLASDLAEVVKLAACDYEKLSQTITDSFQKLKKDPNANP 76
+H I+ + F + + +L +A + A + +L+ Q+ K+D NP
Sbjct 15 EHLIDTQLTRSPFFFASANQSMLGCGVAHAFQ-QAIPFAELANQAKQLLQQAKRDECDNP 73
Query 77 ILVGAIPFDTTQASSLNIYRNHRKQRQLVISSKITHSPLSISNQKPLI----KQKDFAHA 132
+L G +PFD + I R V SS + P ++ Q + + +
Sbjct 74 LLFGIVPFDPKTPTRFMIPRT-----LYVSSSPRLNRPAHLTRQVAKLISSPSGEQYKQG 128
Query 133 IDIAIDQFRCDQLEKVVLSQAVDFELSQSQNPFDLVDTLAKENPHAFSFAIPVEDNAYLL 192
+ ++ F L KVVLS+A++ Q L+ +L N H ++FA +++ L+
Sbjct 129 VSHLLNMFHHSGLSKVVLSRAIEIATEQEIALPTLLRSLLAINHHGYTFAASLDEQRKLI 188
Query 193 GASPELLISKNDLTVRSNPLAGSRPLSEDENINQSRIHELYASEKDLNEHQIVVDSVLEN 252
GASPELL++K + SNPLAGSRP S+D N R L + KDL+EH +VV+ V
Sbjct 189 GASPELLVAKRGNYLISNPLAGSRPRSQDAQENAQRRASLLNTAKDLHEHGLVVEEVERI 248
Query 253 LKPFCQKLKVLEKPEILKTATMLHLSTVFDGQLKKQSDNALQLALALHPTPAICGSPTEP 312
+ +C+ L P +++T TMLHLST+ +GQ+ ALQ+A LHPTPA+CG P E
Sbjct 249 MSRYCRNLYTPMVPSVIETETMLHLSTLLEGQVSDPEVCALQVAADLHPTPAVCGFPRES 308
Query 313 AKQFILEHEGYDRHYFAGLVGWMDAQGNGEWAVTIRCGLLNDKKIRLYAGAGIVMGSQAE 372
A Q I E E +DR YF G+VGW DA+GNGEW VTIRC + +++L+AGAGIV S +
Sbjct 309 AYQAIRELEEFDRGYFTGMVGWCDARGNGEWVVTIRCAEVGSHQMKLFAGAGIVDESLPQ 368
Query 373 LEWSETEVKMQTLL 386
E ET KM+T+L
Sbjct 369 SELEETGAKMKTIL 382
>P23300 Putative isochorismate synthase [Aeromonas hydrophila]
Length=396
Score = 229 bits (585), Expect = 5e-75
Identities = 131/361 (36%), Positives = 198/361 (55%), Gaps = 10/361 (3%)
Query 38 LLASDLAEVVKLAACDYEKLSQTITDSFQKLKKDPNANPILVGAIPFDTTQASSLNIYRN 97
L A+D A ++ AC++ L Q I + + ANP+L+G + +S L +
Sbjct 29 LSATDWASLITTPACEWPLLEQQIASALAAARPAGQANPLLIGCLRVRPGGSSCLYVPAA 88
Query 98 HRKQRQL---------VISSKITHSPLSISNQKPLIKQKDFAHAIDIAIDQFRCDQLEKV 148
R + +++++ + IS Q +F ++ A+D F +L KV
Sbjct 89 MSGDRPVPAAQAPVTAAMANQVVEANRVISVQSTP-PASEFQASVSAALDAFAQGRLAKV 147
Query 149 VLSQAVDFELSQSQNPFDLVDTLAKENPHAFSFAIPVEDNAYLLGASPELLISKNDLTVR 208
VLS+ + L Q +P ++ L +NPHAF F++P+ LLGASPELL+ ++ V
Sbjct 148 VLSRKLTLTLHQPADPTQVMARLMAQNPHAFHFSLPLGQGRRLLGASPELLLRVSEGEVF 207
Query 209 SNPLAGSRPLSEDENINQSRIHELYASEKDLNEHQIVVDSVLENLKPFCQKLKVLEKPEI 268
++PLA S + + Q +L AS KD +EH++V+D + L P C++L + P +
Sbjct 208 THPLARSARRASEPAQEQMVARDLLASRKDQHEHKLVIDEIRRVLTPHCRELAIPSSPSL 267
Query 269 LKTATMLHLSTVFDGQLKKQSDNALQLALALHPTPAICGSPTEPAKQFILEHEGYDRHYF 328
+ T T+ HL T G+L + L LA LHPTPA+CG PTE A+QFI E E + R F
Sbjct 268 MSTDTLWHLGTPIAGRLNGGEASVLSLACQLHPTPALCGYPTELARQFIREQEPFRRALF 327
Query 329 AGLVGWMDAQGNGEWAVTIRCGLLNDKKIRLYAGAGIVMGSQAELEWSETEVKMQTLLKT 388
+G+VGW D+QGNGEWAV IRCG+L+ ++ L+AGAGIV GS K+ T+LK
Sbjct 328 SGIVGWCDSQGNGEWAVVIRCGVLDGHQVELFAGAGIVAGSDPPWSGPRPGTKLGTMLKA 387
Query 389 L 389
L
Sbjct 388 L 388
>P9WFW9 Putative isochorismate synthase MenF [Mycobacterium tuberculosis
(strain ATCC 25618 / H37Rv)]
Length=372
Score = 180 bits (456), Expect = 3e-56
Identities = 117/325 (36%), Positives = 178/325 (55%), Gaps = 15/325 (5%)
Query 76 PILVGAIPFDTTQASSLNIYRNHRKQRQLVISSKITHSPL-SISNQKPLIKQKDFAHAID 134
PIL+GA+PFD ++ ++L + + R+L PL + L D+ I
Sbjct 48 PILLGALPFDVSRPAALMVPDGVLRARKL---PDWPTGPLPKVRVAAALPPPADYLTRIG 104
Query 135 IAIDQFRC--DQLEKVVLSQAVDFELSQSQNPFDLVDTLAKENPHAFSFAIPV------E 186
A D L KVVL++AV + L+ L +P A+ + + + +
Sbjct 105 RARDLLAAFDGPLHKVVLARAVQLTADAPLDARVLLRRLVVADPTAYGYLVDLTSAGNDD 164
Query 187 DNAYLLGASPELLISKNDLTVRSNPLAGSRPLSEDENINQSRIHELYASEKDLNEHQIVV 246
A L+GASPELL++++ V P AGS P + D ++ + L +S K+ +EHQ+VV
Sbjct 165 TGAALVGASPELLVARSGNRVMCKPFAGSAPRAADPKLDAANAAALASSAKNRHEHQLVV 224
Query 247 DSVLENLKPFCQKLKVLEKPEILKTATMLHLSTVFDGQLKKQSDNALQLALALHPTPAIC 306
D++ L+P C+ L + +P++ +TA + HL T G+L+ S A+ LALALHPTPA+
Sbjct 225 DTMRVALEPLCEDLTIPAQPQLNRTAAVWHLCTAITGRLRNISTTAIDLALALHPTPAVG 284
Query 307 GSPTEPAKQFILEHEGYDRHYFAGLVGWMDAQGNGEWAVTIRCGLLN-DKKIRL-YAGAG 364
G PT+ A + I E EG DR ++AG VGW D +G+G W V+IRC L+ D++ L +AG G
Sbjct 285 GVPTKAATELIAELEG-DRGFYAGAVGWCDGRGDGHWVVSIRCAQLSADRRAALAHAGGG 343
Query 365 IVMGSQAELEWSETEVKMQTLLKTL 389
IV S + E ET K T+L L
Sbjct 344 IVAESDPDDELEETTTKFATILTAL 368
>P9WFW8 Putative isochorismate synthase MenF [Mycobacterium tuberculosis
(strain CDC 1551 / Oshkosh)]
Length=372
Score = 180 bits (456), Expect = 3e-56
Identities = 117/325 (36%), Positives = 178/325 (55%), Gaps = 15/325 (5%)
Query 76 PILVGAIPFDTTQASSLNIYRNHRKQRQLVISSKITHSPL-SISNQKPLIKQKDFAHAID 134
PIL+GA+PFD ++ ++L + + R+L PL + L D+ I
Sbjct 48 PILLGALPFDVSRPAALMVPDGVLRARKL---PDWPTGPLPKVRVAAALPPPADYLTRIG 104
Query 135 IAIDQFRC--DQLEKVVLSQAVDFELSQSQNPFDLVDTLAKENPHAFSFAIPV------E 186
A D L KVVL++AV + L+ L +P A+ + + + +
Sbjct 105 RARDLLAAFDGPLHKVVLARAVQLTADAPLDARVLLRRLVVADPTAYGYLVDLTSAGNDD 164
Query 187 DNAYLLGASPELLISKNDLTVRSNPLAGSRPLSEDENINQSRIHELYASEKDLNEHQIVV 246
A L+GASPELL++++ V P AGS P + D ++ + L +S K+ +EHQ+VV
Sbjct 165 TGAALVGASPELLVARSGNRVMCKPFAGSAPRAADPKLDAANAAALASSAKNRHEHQLVV 224
Query 247 DSVLENLKPFCQKLKVLEKPEILKTATMLHLSTVFDGQLKKQSDNALQLALALHPTPAIC 306
D++ L+P C+ L + +P++ +TA + HL T G+L+ S A+ LALALHPTPA+
Sbjct 225 DTMRVALEPLCEDLTIPAQPQLNRTAAVWHLCTAITGRLRNISTTAIDLALALHPTPAVG 284
Query 307 GSPTEPAKQFILEHEGYDRHYFAGLVGWMDAQGNGEWAVTIRCGLLN-DKKIRL-YAGAG 364
G PT+ A + I E EG DR ++AG VGW D +G+G W V+IRC L+ D++ L +AG G
Sbjct 285 GVPTKAATELIAELEG-DRGFYAGAVGWCDGRGDGHWVVSIRCAQLSADRRAALAHAGGG 343
Query 365 IVMGSQAELEWSETEVKMQTLLKTL 389
IV S + E ET K T+L L
Sbjct 344 IVAESDPDDELEETTTKFATILTAL 368
>P23973 Isochorismate synthase MenF [Bacillus subtilis (strain
168)]
Length=471
Score = 149 bits (376), Expect = 8e-44
Identities = 95/266 (36%), Positives = 146/266 (55%), Gaps = 2/266 (1%)
Query 124 IKQKDFAHAIDIAIDQFRCDQLEKVVLSQAVDFELSQSQNPFDLVDTLAKENPHAFSFAI 183
+ + D+ AI+ A Q + Q +KVVL++ + ++ TL + ++ FAI
Sbjct 203 LDKDDWLKAIETATSQIKEKQYDKVVLARELLLTFDGPIQIEPVLKTLLDDQQTSYVFAI 262
Query 184 PVEDNAYLLGASPELLISKNDLTVRSNPLAGSRPLSEDENINQSRIHELYASEKDLNEHQ 243
E ++ GASPE LI ++ TV S+ LAGS +E ++ EL EK+L EH
Sbjct 263 EQEGKTFV-GASPERLIKRDGGTVMSSCLAGSIKRGVNEEDDRRIGLELLNDEKNLLEHD 321
Query 244 IVVDSVLENLKPFCQKLKVLEKPEILKTATMLHLSTVFDGQLKKQSDNALQLALALHPTP 303
IVV + C +++ + P + KT ++ HL T GQL+ +S + L LHPTP
Sbjct 322 IVVGMIHNAFVSSCSEVEKPDGPVLYKTKSVQHLFTPIVGQLR-ESASIFDLIEKLHPTP 380
Query 304 AICGSPTEPAKQFILEHEGYDRHYFAGLVGWMDAQGNGEWAVTIRCGLLNDKKIRLYAGA 363
A+ GSP E A I E E R ++A +GW+D+Q NGE+AV IR GL+ RL+AG
Sbjct 381 ALGGSPQEKAVDVIREIEPMSRGWYAAPIGWIDSQDNGEFAVAIRSGLIEGSTARLFAGC 440
Query 364 GIVMGSQAELEWSETEVKMQTLLKTL 389
GIV S+ E+ ET++K++ ++ L
Sbjct 441 GIVEDSEPISEYEETQIKLKPMISAL 466
>Q9CPI5 Isochorismate synthase MenF [Pasteurella multocida (strain
Pm70)]
Length=431
Score = 137 bits (345), Expect = 1e-39
Identities = 90/279 (32%), Positives = 149/279 (53%), Gaps = 9/279 (3%)
Query 115 LSISNQKPLIKQKDFAHAIDIAIDQFRCDQLEKVVLSQAVDFELSQSQNPFDLVDTLAKE 174
+S+ +QK Q ++ ++ + + + +L K+VL+ F+ + DL+ K
Sbjct 153 ISLISQKA--DQAEWCRWVEQGLQKIKQGELSKIVLANERCFKTAAPLAATDLLAESEKY 210
Query 175 NPHAFSFAIPVEDNAYLLGASPELLISKNDLTVRSNPLAGSRPLSEDENINQSRIHELYA 234
N + F + + +G+SPELL ++ L +++ LAG+ + EDE NQ + L
Sbjct 211 NLGCYHFMLAESEQRAFIGSSPELLYRRHGLQLKTEALAGTAFMGEDEQQNQQQSDWLLH 270
Query 235 SEKDLNEHQIVVDSVLENLKPFCQKLKVLEKPEILKTATMLHLSTVFDGQLKKQSDNALQ 294
+K+ E+Q+VVD + +NL+PF Q++ +EK E+ K + HL QLK +
Sbjct 271 DKKNEYENQLVVDGICQNLQPFVQQI-TIEKVELKKLRKVQHLRRRISAQLKAGCGDK-D 328
Query 295 LALALHPTPAICGSPTEPAKQFILEHEGYDRHYFAGLVGWMDAQGNGEWAVTIRCGLL-- 352
+ LA+HPT A+ G P AKQ + + E +DR ++AG +G M ++ VTIR +
Sbjct 329 ILLAMHPTAAVAGLPQLEAKQALRKLENFDRTWYAGTLGVM-GPAYADFCVTIRSAFIEQ 387
Query 353 --NDKKIRLYAGAGIVMGSQAELEWSETEVKMQTLLKTL 389
ND ++ ++AGAGIV GS LEW E E K L+ L
Sbjct 388 AENDSQLCVFAGAGIVEGSIPLLEWREIERKAMGLVSLL 426
>Q51508 Salicylate biosynthesis isochorismate synthase [Pseudomonas
aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116
/ JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)]
Length=476
Score = 136 bits (342), Expect = 5e-39
Identities = 86/267 (32%), Positives = 144/267 (54%), Gaps = 3/267 (1%)
Query 125 KQKDFAHAIDIAIDQFRCDQLEKVVLSQAVDFELSQSQNPFDLVDTLAKENPHAFSFAIP 184
+++ + + A+ R + KVVL++ L + P+ +++ L ++ A FA
Sbjct 199 ERRQWEAKVSDAVSSVRQGRFGKVVLARTQARPLGDIE-PWQVIEHLRLQHADAQLFACR 257
Query 185 VEDNAYLLGASPELLISKNDLTVRSNPLAGSRPLSEDENINQSRIHELYASEKDLNEHQI 244
NA LGASPE L+ ++ LAG+ D + L S KD +EHQ+
Sbjct 258 -RGNACFLGASPERLVRIRAGEALTHALAGTIARGGDAQEDARLGQALLDSAKDRHEHQL 316
Query 245 VVDSVLENLKPFCQKLKVLEKPEILKTATMLHLSTVFDGQLKKQSDNALQLALALHPTPA 304
VV+++ L+PF + L++ + P + + A + HL+T +L + L+L ALHPTPA
Sbjct 317 VVEAIRTALEPFSEVLEIPDAPGLKRLARVQHLNTPIRARLA-DAGGILRLLQALHPTPA 375
Query 305 ICGSPTEPAKQFILEHEGYDRHYFAGLVGWMDAQGNGEWAVTIRCGLLNDKKIRLYAGAG 364
+ G P A +I +HEG DR ++A +GW+D +GNG++ V +R LL + L+AG G
Sbjct 376 VGGYPRSAALDYIRQHEGMDRGWYAAPLGWLDGEGNGDFLVALRSALLTPGRGYLFAGCG 435
Query 365 IVMGSQAELEWSETEVKMQTLLKTLSA 391
+V S+ E+ ET +K+ + + LSA
Sbjct 436 LVGDSEPAHEYRETCLKLSAMREALSA 462
>Q9ZPC0 Isochorismate synthase, chloroplastic [Catharanthus roseus]
Length=580
Score = 136 bits (343), Expect = 1e-38
Identities = 77/246 (31%), Positives = 131/246 (53%), Gaps = 3/246 (1%)
Query 145 LEKVVLSQAVDFELSQSQNPFDLVDTLAKENPHAFSFAIPVEDNAYLLGASPELLISKND 204
L KVVL++ + +P + + + A+ F + + +G +PE L ++
Sbjct 329 LTKVVLARRSQVITTSDIDPLAWLSSFKADGKDAYQFCLQPHEAPAFIGNTPEQLFGRDQ 388
Query 205 LTVRSNPLAGSRPLSEDENINQSRIHELYASEKDLNEHQIVVDSVLENLKPFCQKLKVLE 264
LTV S LA +R E ++++ H+L++S KD +E IV +++ + L C ++
Sbjct 389 LTVFSEALAATRARGESDSLDLQMAHDLFSSPKDNHEFAIVRENIRQKLDAICTSVETEP 448
Query 265 KPEILKTATMLHLSTVFDGQLKKQSDNALQLALALHPTPAICGSPTEPAKQFILEHEGYD 324
+ K + HL F G+L+ + D+ ++ +LHPTPA+CG P E A++FI E+E +D
Sbjct 449 MKSVRKLKRIQHLYARFAGRLRSE-DDEFKILSSLHPTPAVCGFPMEDARKFIAENEMFD 507
Query 325 RHYFAGLVGWMDAQGNGEWAVTIRCGLL-NDKKIRLYAGAGIVMGSQAELEWSETEVKMQ 383
R +AG VG+ +++V IR L+ D +YAG G+V GS LEW E E+K
Sbjct 508 RGLYAGPVGFFGG-AQSDFSVGIRSALIGKDAGALIYAGLGVVEGSDPALEWQELELKAS 566
Query 384 TLLKTL 389
+K +
Sbjct 567 QFMKLM 572
>Q06128 Anthranilate synthase component 1 [Saccharolobus solfataricus
(strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)]
Length=421
Score = 131 bits (330), Expect = 1e-37
Identities = 89/264 (34%), Positives = 137/264 (52%), Gaps = 6/264 (2%)
Query 124 IKQKDFAHAIDIAIDQFRCDQLEKVVLSQAVDFELSQSQNPFDLVDTLAKENPHAFSFAI 183
+ + + + +++ R + +VVLS+ + S +P + L + NP + F +
Sbjct 155 LNKNSYERIVSESLEYIRSGYIFQVVLSRFYRYIFSG--DPLRIYYNLRRINPSPYMFYL 212
Query 184 PVEDNAYLLGASPELLISKNDLTVRSNPLAGSRPLSEDENINQSRIHELYASEKDLNEHQ 243
D YL+G+SPELL D V + P+AG+RP D+ + EL SEKD EH
Sbjct 213 KF-DEKYLIGSSPELLFRVQDNIVETYPIAGTRPRGADQEEDLKLELELMNSEKDKAEHL 271
Query 244 IVVDSVLENLKPFCQK--LKVLEKPEILKTATMLHLSTVFDGQLKKQSDNALQLALALHP 301
++VD +L C +KV E + K + + H+ + G LKK+ NAL + A P
Sbjct 272 MLVDLARNDLGKVCVPGTVKVPELMYVEKYSHVQHIVSKVIGTLKKKY-NALNVLSATFP 330
Query 302 TPAICGSPTEPAKQFILEHEGYDRHYFAGLVGWMDAQGNGEWAVTIRCGLLNDKKIRLYA 361
+ G+P A I E Y R +AG VG++ A GN E+A+ IR LN + +R++A
Sbjct 331 AGTVSGAPKPMAMNIIETLEEYKRGPYAGAVGFISADGNAEFAIAIRTAFLNKELLRIHA 390
Query 362 GAGIVMGSQAELEWSETEVKMQTL 385
GAGIV S E E+ ETE K++ L
Sbjct 391 GAGIVYDSNPESEYFETEHKLKAL 414
>Q9M9V6 Isochorismate synthase 2, chloroplastic [Arabidopsis thaliana]
Length=562
Score = 129 bits (323), Expect = 5e-36
Identities = 97/303 (32%), Positives = 148/303 (49%), Gaps = 13/303 (4%)
Query 88 QASSLNIYRNHRKQRQLVISSKITHSPLSISNQKPLIKQKDFAHAIDIAIDQFRCDQLEK 147
Q SS+ I R R+ +++ SK H P S P + +A++I D+ L K
Sbjct 262 QVSSV-IMRLRRESLGVIVVSK-NHVP-SEGAYYPAVN-----NALEIIKDKH--SPLSK 311
Query 148 VVLSQAVDFELSQSQNPFDLVDTLAKENPHAFSFAIPVEDNAYLLGASPELLISKNDLTV 207
VVL+++ +P + L E A+ F + +G +PE L + L V
Sbjct 312 VVLARSSRIITDTDIDPIAWLARLQCEGQDAYQFCLQPPGAPAFIGNTPERLFHRKHLGV 371
Query 208 RSNPLAGSRPLSEDENINQSRIHELYASEKDLNEHQIVVDSVLENLKPFCQKLKVLEKPE 267
S LA +RP + + +L S KD E IV +++ E LK C ++ V
Sbjct 372 CSEALAATRPRGDSKVREMEIERDLLTSPKDDLEFSIVRENIREKLKTICDRVVVKPHKS 431
Query 268 ILKTATMLHLSTVFDGQLKKQSDNALQLALALHPTPAICGSPTEPAKQFILEHEGYDRHY 327
+ K A + HL + GQLK++ D+ + ALHPTPA+CG P E A+ I + E +DR
Sbjct 432 VRKLARVQHLYSQLAGQLKRE-DDEFNILTALHPTPAVCGCPVEEARLLIKQIESFDRGM 490
Query 328 FAGLVGWMDAQGNGEWAVTIRCGLL-NDKKIRLYAGAGIVMGSQAELEWSETEVKMQTLL 386
+AG +G+ G E++V IR L+ +YAG GIV GS EW+E E+K+
Sbjct 491 YAGPIGFFGG-GESEFSVGIRSALVEKGLGALIYAGTGIVSGSNPSSEWNELELKISQFT 549
Query 387 KTL 389
K+L
Sbjct 550 KSL 552
>P38051 Isochorismate synthase MenF [Escherichia coli (strain
K12)]
Length=431
Score = 127 bits (318), Expect = 6e-36
Identities = 83/261 (32%), Positives = 135/261 (52%), Gaps = 13/261 (5%)
Query 133 IDIAIDQFRCDQLEKVVLSQAVDFELSQSQNPFDLVDTLAKENPHAFSFAIPVEDNAYLL 192
I++A +L+KVVL++A D + N ++ + N + + F + + L
Sbjct 176 IELATKTIAEGELDKVVLARATDLHFASPVNAAAMMAASRRLNLNCYHFYMAFDGENAFL 235
Query 193 GASPELLISKNDLTVRSNPLAGSRPLSEDENINQSRIHELYASEKDLNEHQIVVDSVLEN 252
G+SPE L + D +R+ LAG+ + D+ Q L A +K+ E+ +VV+ + +
Sbjct 236 GSSPERLWRRRDKALRTEALAGTVANNPDDKQAQQLGEWLMADDKNQRENMLVVEDICQR 295
Query 253 LKPFCQKLKVLEKPEILKTATMLHLSTVFDGQLKKQSDNALQLALALH---PTPAICGSP 309
L+ Q L VL P++L+ + HL L K D + LH PT A+ G P
Sbjct 296 LQADTQTLDVL-PPQVLRLRKVQHLRRCIWTSLNKADD-----VICLHQLQPTAAVAGLP 349
Query 310 TEPAKQFILEHEGYDRHYFAGLVGWMDAQGNGEWAVTIRCGLLNDKKIRLYAGAGIVMGS 369
+ A+QFI HE + R ++AG G++ Q E+ V++R ++ +RLYAGAGIV GS
Sbjct 350 RDLARQFIARHEPFTREWYAGSAGYLSLQ-QSEFCVSLRSAKISGNVVRLYAGAGIVRGS 408
Query 370 QAELEWSETEVK---MQTLLK 387
E EW E + K ++TLL+
Sbjct 409 DPEQEWQEIDNKAAGLRTLLQ 429
Lambda K H a alpha
0.318 0.133 0.384 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1863902
Database: 50e96fae3b6f62275631f6a103efc47c.SwissProt.fasta
Posted date: May 20, 2024 8:46 PM
Number of letters in database: 6,087
Number of sequences in database: 14
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
