BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: a6ba35aa1bf42eac70f9cd82aeaf0d17.SwissProt.fasta
11 sequences; 2,964 total letters
Query= ACIAD2817
Length=254
Score E
Sequences producing significant alignments: (Bits) Value
P42968 HTH-type transcriptional regulator KipR [Bacillus subtilis... 82.4 2e-22
P77300 HTH-type transcriptional regulator XynR [Escherichia coli ... 78.6 6e-21
P44996 Uncharacterized HTH-type transcriptional regulator HI_1032... 77.0 3e-20
P17430 Acetate operon repressor [Salmonella typhimurium (strain L... 67.0 1e-16
P76268 HTH-type transcriptional regulator KdgR [Escherichia coli ... 66.2 2e-16
P16528 Transcriptional repressor IclR [Escherichia coli (strain K... 66.2 2e-16
Q52154 Pca regulon regulatory protein [Pseudomonas putida] 66.2 2e-16
P37671 DNA-binding transcriptional repressor YiaJ [Escherichia co... 62.8 4e-15
P37728 HTH-type transcriptional regulator KdgR [Dickeya chrysanth... 62.4 6e-15
D4GP42 HTH-type transcriptional regulator XacR [Haloferax volcani... 60.5 2e-14
P22866 Glycerol operon regulatory protein [Streptomyces griseus] 54.7 2e-12
>P42968 HTH-type transcriptional regulator KipR [Bacillus subtilis
(strain 168)]
Length=250
Score = 82.4 bits (202), Expect = 2e-22
Identities = 51/242 (21%), Positives = 122/242 (50%), Gaps = 25/242 (10%)
Query 22 VDRALLILSSFDIENPSLSLAEISRRTKLYKSTILRLLNSLERHGYIRKNTDGLYSLSIM 81
V +++ +L+ F + PSL+L+E+ T + K+++ R+++SLE G++ ++ G YSL ++
Sbjct 8 VVKSMALLNLF-LHKPSLTLSELVSLTGMPKTSVHRMVSSLEEMGFLSRDASGAYSLGLV 66
Query 82 PLKLARIYQNSFNLKDIIYPILEKISEETGETSSFYILDNESRVVLFRIEPVRSVKVSIS 141
L+ ++ + +++ I P++E++ E E + D + + +IE ++V++ +
Sbjct 67 FLEFGQLVADRLDIRKIAKPVMEELCREVDEAVQLIMRDGNEAIYVEKIEGTQTVRLYTA 126
Query 142 EGDVFPVNVGASGK-ILSAFSKQQIEARLEPIK-----------------------ENYW 177
G P+ GA + ILS +++IEA ++ + +N +
Sbjct 127 IGRRSPLYAGACARSILSFLPREEIEAYIKQTELISIGSGTITDPEKLLQEIDASVQNGY 186
Query 178 ASSFGERDPETSSLSVPVLDGSQYLQGALTISGPSERLTSETINGYIPHLMKYGITISKQ 237
S+ E + T+++ P+ + + + ++I+G R T + + + + IS++
Sbjct 187 TVSYSELENYTAAIGAPIFNHERQVAAGISIAGFEARFTEDRLPYLTEKVKDAALQISRK 246
Query 238 LG 239
+G
Sbjct 247 IG 248
>P77300 HTH-type transcriptional regulator XynR [Escherichia coli
(strain K12)]
Length=252
Score = 78.6 bits (192), Expect = 6e-21
Identities = 62/246 (25%), Positives = 112/246 (46%), Gaps = 25/246 (10%)
Query 19 VAAVDRALLILSSFDIENPSLSLAEISRRTKLYKSTILRLLNSLERHGYIRKNTD-GLYS 77
+ +V+RAL IL F+ + L + +IS+ L KST+ LL +L+ HGYI +N + G Y
Sbjct 4 IQSVERALQILDLFNEQATELKITDISKLMGLSKSTLHSLLKTLQLHGYIDQNPENGKYR 63
Query 78 LSIMPLKLARIYQNSFNLKDIIYPILEKISEETGETSSFYILDNESRVVLFRIEPVRSVK 137
L + ++ S +++ L ++S TG+T+ ILD V + +IE +
Sbjct 64 LGMKLVERGHFVVGSIDIRQKAKGWLTELSRRTGQTTHLGILDGREGVYIEKIEGKLAAI 123
Query 138 VSISEGDVFPVNVGASGKILSAF------------------------SKQQIEARLEPIK 173
G PV+ A GK+L A+ S++ + + L +
Sbjct 124 AYSRIGRRLPVHATAIGKVLIAWLGEAELNALLEGYQYTTFTPATLASREALMSALAQTR 183
Query 174 ENYWASSFGERDPETSSLSVPVLDGSQYLQGALTISGPSERLTSETINGYIPHLMKYGIT 233
E +A E + ++VPV + + AL++S + R+ + + L + G+
Sbjct 184 EQGYALDSEENEQGVRCVAVPVWNHESRVIAALSLSTLTSRVDDAELANFREQLQQAGLA 243
Query 234 ISKQLG 239
+S+ LG
Sbjct 244 LSRALG 249
>P44996 Uncharacterized HTH-type transcriptional regulator HI_1032
[Haemophilus influenzae (strain ATCC 51907 / DSM 11121
/ KW20 / Rd)]
Length=268
Score = 77.0 bits (188), Expect = 3e-20
Identities = 60/263 (23%), Positives = 117/263 (44%), Gaps = 29/263 (11%)
Query 6 NEDLGSDSKQNSGVAAVDRALLILSSFDIENPSLSLAEISRRTKLYKSTILRLLNSLERH 65
N ++ + +++ G A+ R L +L LA+++ L KST RLL L+
Sbjct 2 NIEVKMEKEKSLGNQALIRGLRLLDILSNYPNGCPLAKLAELANLNKSTAHRLLQGLQNE 61
Query 66 GYIRK-NTDGLYSLSIMPLKLARIYQNSFNLKDIIYPILEKISEETGETSSFYILDNESR 124
GY++ N G Y L+I L + + +S N+ + P LE+++ + GET +F +++
Sbjct 62 GYVKPANAAGSYRLTIKCLSIGQKVLSSMNIIHVASPYLEQLNLKLGETINFSKREDDHA 121
Query 125 VVLFRIEPVRS-VKVSISEGDVFPVNVGASGKILSAFSKQ-------------------- 163
++++++EP +K G + A GKI A+ K+
Sbjct 122 IMIYKLEPTNGMLKTRAYIGQYLKLYCSAMGKIFLAYEKKVDYLSHYWQSHQREIKKLTR 181
Query 164 -------QIEARLEPIKENYWASSFGERDPETSSLSVPVLDGSQYLQGALTISGPSERLT 216
I+ LE I++ +A E + + ++ P+ D ++ A+++S RL
Sbjct 182 YTITELDDIKLELETIRQTAYAMDREENELGVTCIACPIFDSFGQVEYAISVSMSIYRLN 241
Query 217 SETINGYIPHLMKYGITISKQLG 239
+ ++ + K IS +LG
Sbjct 242 KFGTDAFLQEIRKTAEQISLELG 264
>P17430 Acetate operon repressor [Salmonella typhimurium (strain
LT2 / SGSC1412 / ATCC 700720)]
Length=274
Score = 67.0 bits (162), Expect = 1e-16
Identities = 55/229 (24%), Positives = 112/229 (49%), Gaps = 27/229 (12%)
Query 19 VAAVDRALLILSSFDIENPSLSLAEISRRTKLYKSTILRLLNSLERHGYIRKNTD-GLYS 77
V ++ R L +L N S++L E++++ L ST RLL ++++ G++R+ + G ++
Sbjct 24 VQSLTRGLKLLEWIAESNGSVALTELAQQAGLPNSTTHRLLTTMQQQGFVRQVGELGHWA 83
Query 78 LSIMPLKLARIYQNSFNLKDIIYPILEKISEETGETSSFYILDNESR--VVLFRIEPVRS 135
+ + + S NL I++PIL K+ E++GET + +LD +++ +++ +
Sbjct 84 VGAHAFIVGSSFLQSRNLLAIVHPILRKLMEDSGETVNLAVLDQSDHQAIIIDQVQCTQL 143
Query 136 VKVSISEGDVFPVNVGASGK-ILSAFSKQQIEARLE--------------PIKENYWASS 180
+++S G P++ +GK LS S++Q+ + L P+ +
Sbjct 144 MRMSAPIGGKLPMHASGAGKAFLSQLSEEQVTSLLHRKGLHAYTHATLVSPLHLKDDLAQ 203
Query 181 FGER----DPETSSLSVPVLDGSQYLQ-----GALTISGPSERLTSETI 220
+R D E +L + + Y + AL+ISGP R+T + +
Sbjct 204 TRKRGYSFDDEEHALGLRCVASCIYDEHREPFAALSISGPCSRITDDRV 252
>P76268 HTH-type transcriptional regulator KdgR [Escherichia coli
(strain K12)]
Length=263
Score = 66.2 bits (160), Expect = 2e-16
Identities = 69/262 (26%), Positives = 120/262 (46%), Gaps = 31/262 (12%)
Query 4 LSNEDLGSDSKQNSGVAAVDRALLILSSFDIENPSLSLAEISRRTKLYKSTILRLLNSLE 63
++N DL KQ V++V + IL + E + + E+S+R + KST+ R L +++
Sbjct 1 MANADL---DKQPDSVSSVLKVFGILQALG-EEREIGITELSQRVMMSKSTVYRFLQTMK 56
Query 64 RHGYIRKNTDG-LYSLSIMPLKL-ARIYQNSFNLKDIIYPILEKISEETGETSSFYILDN 121
GY+ + + YSL++ +L AR QN ++ + E +S T ET LD
Sbjct 57 TLGYVAQEGESEKYSLTLKLFELGARALQNVDLIRSADIQMRE-LSRLTKETIHLGALDE 115
Query 122 ESRVVLFRIEPVRSVKVSISEGDVFPVNVGASGKILSAFS-----KQQIEA--------- 167
+S V + +I+ + ++++ G P+ A GK+L A+ KQ +E
Sbjct 116 DSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRDEVKQILEGVEYKRSTER 175
Query 168 ------RLEPIKENYWASSFGERDPETSS----LSVPVLDGSQYLQGALTISGPSERLTS 217
L P+ + +GE + E ++VPV D + L+IS P+ R +
Sbjct 176 TITSTEALLPVLDQVREQGYGEDNEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFSE 235
Query 218 ETINGYIPHLMKYGITISKQLG 239
E + Y+ L IS Q+G
Sbjct 236 ERLQEYVAMLHTAARKISAQMG 257
>P16528 Transcriptional repressor IclR [Escherichia coli (strain
K12)]
Length=274
Score = 66.2 bits (160), Expect = 2e-16
Identities = 53/232 (23%), Positives = 112/232 (48%), Gaps = 27/232 (12%)
Query 19 VAAVDRALLILSSFDIENPSLSLAEISRRTKLYKSTILRLLNSLERHGYIRKNTD-GLYS 77
V ++ R L +L N S++L E++++ L ST RLL ++++ G++R+ + G ++
Sbjct 24 VQSLTRGLKLLEWIAESNGSVALTELAQQAGLPNSTTHRLLTTMQQQGFVRQVGELGHWA 83
Query 78 LSIMPLKLARIYQNSFNLKDIIYPILEKISEETGETSSFYILD--NESRVVLFRIEPVRS 135
+ + + S NL I++PIL + EE+GET + +LD + +++ +++
Sbjct 84 IGAHAFMVGSSFLQSRNLLAIVHPILRNLMEESGETVNMAVLDQSDHEAIIIDQVQCTHL 143
Query 136 VKVSISEGDVFPVNVGASGK-ILSAFSKQQIEARLE----------------PIKENYWA 178
+++S G P++ +GK L+ S++Q+ L +KE+
Sbjct 144 MRMSAPIGGKLPMHASGAGKAFLAQLSEEQVTKLLHRKGLHAYTHATLVSPVHLKEDLAQ 203
Query 179 S-----SFGERDPETS--SLSVPVLDGSQYLQGALTISGPSERLTSETINGY 223
+ SF + + L+ + D + A++ISGP R+T + + +
Sbjct 204 TRKRGYSFDDEEHALGLRCLAACIFDEHREPFAAISISGPISRITDDRVTEF 255
>Q52154 Pca regulon regulatory protein [Pseudomonas putida]
Length=291
Score = 66.2 bits (160), Expect = 2e-16
Identities = 61/247 (25%), Positives = 112/247 (45%), Gaps = 29/247 (12%)
Query 19 VAAVDRALLILSSFDIENPSLSLAEISRRTKLYKSTILRLLNSLERHGYIRKNTDG-LYS 77
+ ++ R L ++ +F L++A+IS RT++ ++ + R L++L + GY +DG YS
Sbjct 45 MTSLARGLAVIQAFQERKRHLTIAQISHRTEIPRAAVRRCLHTLIKLGY--ATSDGRTYS 102
Query 78 LSIMPLKLARIYQNSFNLKDIIYPILEKISEETGETSSFYILDNESRVVLFRIEPV-RSV 136
L L L Y +S L P L++IS++ E ++ L+ + + + R V R +
Sbjct 103 LLPKVLTLGHAYLSSTPLAISAQPYLDRISDQLHEAANMATLEGDDILYIARSATVERLI 162
Query 137 KVSISEGDVFPVNVGASGKILSA----------FSKQQIEAR--------------LEPI 172
V +S G P + G+IL A + ++AR ++ +
Sbjct 163 SVDLSVGGRLPAYCTSMGRILLAAMDDTSLREYLGRADLKARTSRTLHDPESLFACIQQV 222
Query 173 KENYWASSFGERDPETSSLSVPVLDGSQYLQGALTISGPSERLT-SETINGYIPHLMKYG 231
+ W E + S++VP+ D S + AL +S R+T SE ++P L+
Sbjct 223 RAQGWCVVDQELEQGLRSIAVPIYDASGQVLAALNVSTHVGRVTRSELEQRFLPILLAAS 282
Query 232 ITISKQL 238
+ QL
Sbjct 283 RDLCHQL 289
>P37671 DNA-binding transcriptional repressor YiaJ [Escherichia
coli (strain K12)]
Length=282
Score = 62.8 bits (151), Expect = 4e-15
Identities = 61/260 (23%), Positives = 112/260 (43%), Gaps = 28/260 (11%)
Query 8 DLGSDSKQNSGVAAVDRALLILSSFDIENPSLSLAEISRRTKLYKSTILRLLNSLERHGY 67
++ + ++ +G ++ R L+++ LA +S L KST+ RLL L+ GY
Sbjct 12 EMAQEKERPAGSQSLFRGLMLIEILSNYPNGCPLAHLSELAGLNKSTVHRLLQGLQSCGY 71
Query 68 IRKN-TDGLYSLSIMPLKLARIYQNSFNLKDIIYPILEKISEETGETSSFYILDNESRVV 126
+ G Y L+ + + + +S N+ I P LE ++ TGET +F +++ ++
Sbjct 72 VTTAPAAGSYRLTTKFIAVGQKALSSLNIIHIAAPHLEALNIATGETINFSSREDDHAIL 131
Query 127 LFRIEPVRS-VKVSISEGDVFPVNVGASGKILSAFS------------KQQIEA------ 167
++++EP ++ G P+ A GKI AF + +I+
Sbjct 132 IYKLEPTTGMLRTRAYIGQHMPLYCSAMGKIYMAFGHPDYVKSYWESHQHEIQPLTRNTI 191
Query 168 --------RLEPIKENYWASSFGERDPETSSLSVPVLDGSQYLQGALTISGPSERLTSET 219
L I+E+ A E + S ++VPV D + A++IS + RL
Sbjct 192 TELPAMFDELAHIRESGAAMDREENELGVSCIAVPVFDIHGRVPYAVSISLSTSRLKQVG 251
Query 220 INGYIPHLMKYGITISKQLG 239
+ L + IS +LG
Sbjct 252 EKNLLKPLRETAQAISNELG 271
>P37728 HTH-type transcriptional regulator KdgR [Dickeya chrysanthemi]
Length=305
Score = 62.4 bits (150), Expect = 6e-15
Identities = 59/254 (23%), Positives = 116/254 (46%), Gaps = 32/254 (13%)
Query 14 KQNSGVAAVDRALLILSSFDIENPSLSLAEISRRTKLYKSTILRLLNSLERHGYIRKNTD 73
KQ V++V + IL + E + + E+S+R + KST+ R L +++ GY+ + +
Sbjct 50 KQPDSVSSVLKVFGILQALG-EEREIGITELSQRVMMSKSTVYRFLQTMKSLGYVAQEGE 108
Query 74 G-LYSLSIMPLKLARIYQNSFNLKDIIYPI---LEKISEETGETSSFYILDNESRVVLFR 129
YSL+ LKL + + D+I + ++S T ET LD +S V + +
Sbjct 109 SEKYSLT---LKLFELGAKALQNVDLIRSADIQMRELSALTRETIHLGALDEDSIVYIHK 165
Query 130 IEPVRSVKVSISEGDVFPVNVGASGKILSAF------------------------SKQQI 165
I+ + ++++ G P++ A GK+L A+ S +++
Sbjct 166 IDSMYNLRMYSRIGRRNPLHSTAIGKVLLAWRDREEVKEILSQVEFKRTTVHTIGSTEEL 225
Query 166 EARLEPIKENYWASSFGERDPETSSLSVPVLDGSQYLQGALTISGPSERLTSETINGYIP 225
+L+ +++ + E++ ++VPV D + L+IS P+ R + + + Y+
Sbjct 226 LPQLDLVRQQGYGEDNEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTIRFSEDNKHEYVA 285
Query 226 HLMKYGITISKQLG 239
L IS Q+G
Sbjct 286 MLHTAARNISDQMG 299
>D4GP42 HTH-type transcriptional regulator XacR [Haloferax volcanii
(strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742
/ NCIMB 2012 / VKM B-1768 / DS2)]
Length=251
Score = 60.5 bits (145), Expect = 2e-14
Identities = 48/231 (21%), Positives = 104/231 (45%), Gaps = 26/231 (11%)
Query 19 VAAVDRALLILSSFDIENPSLSLAEISRRTKLYKSTILRLLNSLERHGYIRKNTDGLYSL 78
V ++ L ++ + P + E++ + KS + L +L++HGY+ K+ D Y +
Sbjct 7 VRTTEKTLALVEELMQKGPC-GVTELAGDLDMGKSAVHNHLTTLQKHGYVLKDGDD-YRV 64
Query 79 SIMPLKLARIYQNSFNLKDIIYPILEKISEETGETSSFYILDNESRVVLFRIEPVRSVKV 138
+ L++ + S + + P ++ ++ +TGE ++ + + V L R + +V +
Sbjct 65 GLKFLEVGGHSRKSMEVYQVAEPEVKSLAADTGELANLLVEEQGMGVYLMRAKGDDAVDL 124
Query 139 SISEGDVFPVNVGASGKIL------------------------SAFSKQQIEARLEPIKE 174
G ++ A GK + S ++Q++ LE ++E
Sbjct 125 DTYAGLRTNLHTTALGKAILANLPESRVDEIIERHGLEQKTPKSIGTRQELFQVLEGVRE 184
Query 175 NYWASSFGERDPETSSLSVPVLDGSQYLQGALTISGPSERLTSETINGYIP 225
+A GER L+ P+ S + GA+++S P+ R++ E ++G +P
Sbjct 185 RGYAIDDGERLEGLRCLAAPIKSSSGEVLGAISVSAPASRVSDEDLHGALP 235
>P22866 Glycerol operon regulatory protein [Streptomyces griseus]
Length=254
Score = 54.7 bits (130), Expect = 2e-12
Identities = 52/247 (21%), Positives = 98/247 (40%), Gaps = 25/247 (10%)
Query 19 VAAVDRALLILSSFDIENPSLSLAEISRRTKLYKSTILRLLNSLERHGYIRKN-TDGLYS 77
+ +++RA +L L L++I+ L K T +L SL+ G++ + G Y
Sbjct 5 IQSLERAAAMLRLLAGGERRLGLSDIASTLGLAKGTAHGILRSLQAEGFVEQEPASGRYQ 64
Query 78 LSIMPLKLARIYQNSFNLKDIIYPILEKISEETGETSSFYILDNESRVVLFRIEPVRSVK 137
L L L Y + L+ + ++ +GE + +L + +++ + +
Sbjct 65 LGAELLALGNSYLDVHELRARALVWTDDLARSSGEAAYLGVLHQQGVLIVHHVFRPDDSR 124
Query 138 VSISEGDVFPVNVGASGKILSAFSK----------------------QQIEARLEPIKEN 175
+ G + P++ A GK++SAF E L+ +
Sbjct 125 QVLEVGAMHPLHSTAHGKVISAFDPVAHSEVLEGDRATLTGRTVTEAAAFEEVLDLTRAR 184
Query 176 YWASSFGERDPETSSLSVPVLDGSQYLQGALTISGPSERLTSE--TINGYIPHLMKYGIT 233
WA E +SL+ PV D + GA+ ++GP ERL + + +
Sbjct 185 GWALDLEETWEGVASLAAPVHDRRRMAVGAVGVTGPVERLCPDGAPATELVTAVRDCAAA 244
Query 234 ISKQLGA 240
+S+ LGA
Sbjct 245 VSRDLGA 251
Lambda K H a alpha
0.316 0.133 0.363 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 535269
Database: a6ba35aa1bf42eac70f9cd82aeaf0d17.SwissProt.fasta
Posted date: Jun 3, 2024 10:40 AM
Number of letters in database: 2,964
Number of sequences in database: 11
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
Loading
Data ...
