BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: c66eea961834533ddabd13d0a78696f8.SwissProt.fasta
           18 sequences; 5,705 total letters



Query= ACIAD2846

Length=223
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q8IXQ9 Electron transfer flavoprotein beta subunit lysine methylt...  72.8    1e-18
Q80ZM3 Electron transfer flavoprotein beta subunit lysine methylt...  70.9    4e-18
A3KP85 Electron transfer flavoprotein beta subunit lysine methylt...  69.7    1e-17
Q6P7Q0 Electron transfer flavoprotein beta subunit lysine methylt...  67.8    6e-17
A4XKA6 Ribosomal protein L11 methyltransferase [Caldicellulosirup...  65.1    8e-16
O67870 Ribosomal protein L11 methyltransferase [Aquifex aeolicus ...  61.6    8e-15
Q3KIP5 Ribosomal protein L11 methyltransferase [Pseudomonas fluor...  59.3    7e-14
Q6F9P9 Ribosomal protein L11 methyltransferase [Acinetobacter bay...  59.3    8e-14
B9MJY9 Ribosomal protein L11 methyltransferase [Caldicellulosirup...  58.5    1e-13
Q12S38 Ribosomal protein L11 methyltransferase [Shewanella denitr...  58.2    2e-13
P0A8T1 Ribosomal protein L11 methyltransferase [Escherichia coli ...  52.0    2e-11
P45558 Ribosomal protein L11 methyltransferase [Clostridium aceto...  50.4    8e-11
O86951 Ribosomal protein L11 methyltransferase [Thermotoga neapol...  46.6    1e-09
G2K044 Ribosomal protein L11 methyltransferase [Listeria monocyto...  46.6    2e-09
O70467 Protein arginine N-methyltransferase 3 [Rattus norvegicus]     45.8    4e-09
O60678 Protein arginine N-methyltransferase 3 [Homo sapiens]          45.8    4e-09
Q9MAT5 Protein arginine N-methyltransferase PRMT10 [Arabidopsis t...  44.7    8e-09
P0A0P5 Ribosomal protein L11 methyltransferase [Staphylococcus au...  44.3    1e-08


>Q8IXQ9 Electron transfer flavoprotein beta subunit lysine methyltransferase 
[Homo sapiens]
Length=262

 Score = 72.8 bits (177),  Expect = 1e-18
 Identities = 43/114 (38%), Positives = 63/114 (55%), Gaps = 4/114 (4%)

Query  64   PYWIFCWASGLAMAQWLLAEPHHVKDKVVLDFGAGSGVVAIAAKMAGAKRVICCDIDETS  123
            PYW   W  G A++++LL  P  V+ K VLD G+G G  AIAAKM+GA R++  DID  +
Sbjct  91   PYWAIYWPGGQALSRYLLDNPDVVRGKSVLDLGSGCGATAIAAKMSGASRILANDIDPIA  150

Query  124  LNACRENALLNNVE---LEYLNDLYLSESV-DILLAADVLYDQSNRFFLDEFLK  173
              A   N  LN +    +   N L L +   D+++  D+ YD+     L ++LK
Sbjct  151  GMAITLNCELNRLNPFPILIQNILNLEQDKWDLVVLGDMFYDEDLADSLHQWLK  204


>Q80ZM3 Electron transfer flavoprotein beta subunit lysine methyltransferase 
[Mus musculus]
Length=255

 Score = 70.9 bits (172),  Expect = 4e-18
 Identities = 56/183 (31%), Positives = 82/183 (45%), Gaps = 34/183 (19%)

Query  8    PKAPEHLLQALNE-------------VIPKCKLMAQQLPETAISLWLIPPV---------  45
            P++P   LQA+N              + PK K   ++  E   S  L P +         
Sbjct  10   PRSPWSFLQAVNNGSPLFLWRTVGSCLDPKMKAYLEENTEVTSSGSLTPEIQLRLLTPRC  69

Query  46   -FPTERLDDDIIRRIWS-DTPYWIFCWASGLAMAQWLLAEPHHVKDKVVLDFGAGSGVVA  103
             F  ER D      +W    PYW   W  G A++++LL  P  V+ K VLD G+G G  A
Sbjct  70   KFWWERAD------LWPYSDPYWAIYWPGGQALSRYLLDNPAVVRGKSVLDLGSGCGATA  123

Query  104  IAAKMAGAKRVICCDIDETSLNACRENALLNNVE-LEYLNDLYLSE---SVDILLAADVL  159
            IAAKM+GA +++  DID  +  A   N  LN +     L    L+      D+++  D+ 
Sbjct  124  IAAKMSGASKILANDIDPIAGMAITLNCKLNGLNPFPVLTKNILNTQQGKFDLIVLGDMF  183

Query  160  YDQ  162
            YD+
Sbjct  184  YDE  186


>A3KP85 Electron transfer flavoprotein beta subunit lysine methyltransferase 
[Danio rerio]
Length=258

 Score = 69.7 bits (169),  Expect = 1e-17
 Identities = 52/162 (32%), Positives = 80/162 (49%), Gaps = 13/162 (8%)

Query  19   NEVIPKCKLMAQQLPETAISLWLIPPV--FPTERLDDDIIRRIWS-DTPYWIFCWASGLA  75
            N +I   +++  Q     ISL L  P   F TE  +       W    PYW   W  G A
Sbjct  41   NFIIDNTEIVNSQSLTPEISLRLFTPTCRFWTENPE------FWPFPDPYWAIYWPGGQA  94

Query  76   MAQWLLAEPHHVKDKVVLDFGAGSGVVAIAAKMAGAKRVICCDIDETSLNACRENALLNN  135
            +A++LL  P     + VLD G G G  AIAA+++GA  V+  DID  +  A + N  LNN
Sbjct  95   LARYLLNNPEVSAGRKVLDLGCGCGASAIAARLSGASCVVANDIDPIAAIATKMNCELNN  154

Query  136  V-ELEYLNDLYL---SESVDILLAADVLYDQSNRFFLDEFLK  173
            +  L  + D  +   ++  D++L  D+ YD++    L ++L+
Sbjct  155  LAPLPCVTDNMIGSETDGWDLILLGDMFYDEALADGLHQWLQ  196


>Q6P7Q0 Electron transfer flavoprotein beta subunit lysine methyltransferase 
[Rattus norvegicus]
Length=255

 Score = 67.8 bits (164),  Expect = 6e-17
 Identities = 55/183 (30%), Positives = 79/183 (43%), Gaps = 34/183 (19%)

Query  8    PKAPEHLLQALNEVIP-------------KCKLMAQQLPETAISLWLIPPV---------  45
            P++    LQALN   P             K K   ++  E   S  L P +         
Sbjct  10   PRSQWSFLQALNSGFPLFPWRTVGSCLDLKMKAYLEENTEVTSSGSLTPEIQLRLLTPRC  69

Query  46   -FPTERLDDDIIRRIWS-DTPYWIFCWASGLAMAQWLLAEPHHVKDKVVLDFGAGSGVVA  103
             F  ER D      +W    PYW   W  G A++++LL  P  V+ K VLD G+G G  A
Sbjct  70   KFWWERAD------LWPYSDPYWAIYWPGGQALSRYLLDNPDVVRGKSVLDLGSGCGATA  123

Query  104  IAAKMAGAKRVICCDIDETSLNACRENALLNNVE-LEYLNDLYLSE---SVDILLAADVL  159
            IAAKM+GA  ++  D+D  +  A   N  LN +     L    L+      D+++  D+ 
Sbjct  124  IAAKMSGASNILANDVDPIAGMAITLNCKLNGLNPFPILTKNILNTRQGKFDLIVLGDMF  183

Query  160  YDQ  162
            YD+
Sbjct  184  YDE  186


>A4XKA6 Ribosomal protein L11 methyltransferase [Caldicellulosiruptor 
saccharolyticus (strain ATCC 43494 / DSM 8903 / Tp8T 
6331)]
Length=302

 Score = 65.1 bits (157),  Expect = 8e-16
 Identities = 37/74 (50%), Positives = 49/74 (66%), Gaps = 6/74 (8%)

Query  92   VLDFGAGSGVVAIAAKMAGAKRVICCDIDETSLNACRENALLNNVELEY-LNDLY--LSE  148
            V+D G GSG++AIAAK  GA RV+  DID+ ++   RENA LNNVE+E   NDL   + E
Sbjct  172  VIDIGTGSGILAIAAKKLGANRVLAVDIDDVAVKVARENAALNNVEIEIKQNDLVFGIEE  231

Query  149  SVDILLA---ADVL  159
              DI +A   AD++
Sbjct  232  KFDIAIANIIADII  245


>O67870 Ribosomal protein L11 methyltransferase [Aquifex aeolicus 
(strain VF5)]
Length=245

 Score = 61.6 bits (148),  Expect = 8e-15
 Identities = 32/66 (48%), Positives = 46/66 (70%), Gaps = 2/66 (3%)

Query  92   VLDFGAGSGVVAIAAKMAGAKRVICCDIDETSLNACRENALLNNVELEYL--NDLYLSES  149
            VLD G GSG++AI + + GAKRV+  DIDE ++N CRENA LN V++E        ++ES
Sbjct  118  VLDVGTGSGILAIVSALLGAKRVVGIDIDEKAVNECRENAELNKVKVECFRAEPKDVNES  177

Query  150  VDILLA  155
             D+++A
Sbjct  178  FDLVVA  183


>Q3KIP5 Ribosomal protein L11 methyltransferase [Pseudomonas fluorescens 
(strain Pf0-1)]
Length=292

 Score = 59.3 bits (142),  Expect = 7e-14
 Identities = 39/82 (48%), Positives = 51/82 (62%), Gaps = 4/82 (5%)

Query  78   QWLLAEPHHVKDKVVLDFGAGSGVVAIAAKMAGAKRVICCDIDETSLNACRENALLNNVE  137
            +WL  +   +KD  VLDFG GSG++AIAA + GAK  +  DID  +L A R+NA  NN+ 
Sbjct  149  EWL--DGQDLKDCNVLDFGCGSGILAIAALLLGAKEAVGTDIDVQALEASRDNAGRNNIA  206

Query  138  LEYLNDLYLSESVDILLAADVL  159
             E L  LYL E +   + ADVL
Sbjct  207  DE-LFPLYLPEELP-QVKADVL  226


>Q6F9P9 Ribosomal protein L11 methyltransferase [Acinetobacter 
baylyi (strain ATCC 33305 / BD413 / ADP1)]
Length=303

 Score = 59.3 bits (142),  Expect = 8e-14
 Identities = 31/66 (47%), Positives = 44/66 (67%), Gaps = 2/66 (3%)

Query  71   ASGLAMAQWLLAEPHHVKDKVVLDFGAGSGVVAIAAKMAGAKRVICCDIDETSLNACREN  130
            AS     QWL      +KDKVV+D+G GSG++A+AA + GA++V   DID  ++ A ++N
Sbjct  144  ASTFLCLQWL--GKTDLKDKVVIDYGCGSGILAVAALLLGAQKVYATDIDPQAVLATKQN  201

Query  131  ALLNNV  136
            A LNNV
Sbjct  202  AELNNV  207


>B9MJY9 Ribosomal protein L11 methyltransferase [Caldicellulosiruptor 
bescii (strain ATCC BAA-1888 / DSM 6725 / KCTC 15123 
/ Z-1320)]
Length=304

 Score = 58.5 bits (140),  Expect = 1e-13
 Identities = 35/74 (47%), Positives = 48/74 (65%), Gaps = 6/74 (8%)

Query  92   VLDFGAGSGVVAIAAKMAGAKRVICCDIDETSLNACRENALLNNVELEY-LNDLY--LSE  148
            VLD G GSG++AIAAK   A+RV+  DIDE ++    ENA LN VE+E   NDL   + E
Sbjct  172  VLDVGTGSGILAIAAKKFLARRVLAVDIDEVAVKVAEENARLNGVEIEIKKNDLVEGIEE  231

Query  149  SVDILLA---ADVL  159
              D+++A   AD++
Sbjct  232  KFDVVVANIVADII  245


>Q12S38 Ribosomal protein L11 methyltransferase [Shewanella denitrificans 
(strain OS217 / ATCC BAA-1090 / DSM 15013)]
Length=293

 Score = 58.2 bits (139),  Expect = 2e-13
 Identities = 36/82 (44%), Positives = 51/82 (62%), Gaps = 4/82 (5%)

Query  78   QWLLAEPHHVKDKVVLDFGAGSGVVAIAAKMAGAKRVICCDIDETSLNACRENALLNNVE  137
            +WL  +   + D+ V+DFG GSG++AIAA   GAK+V   DID  +++A + NA+ NNV+
Sbjct  150  EWL--DSLDLSDEEVIDFGCGSGILAIAALKLGAKKVTGVDIDYQAIDASQANAVRNNVQ  207

Query  138  LEYLNDLYLSESVDILLAADVL  159
             +    LYL E     L ADVL
Sbjct  208  DQLA--LYLPEDQPEGLIADVL  227


>P0A8T1 Ribosomal protein L11 methyltransferase [Escherichia coli 
(strain K12)]
Length=293

 Score = 52.0 bits (123),  Expect = 2e-11
 Identities = 33/82 (40%), Positives = 46/82 (56%), Gaps = 4/82 (5%)

Query  78   QWLLAEPHHVKDKVVLDFGAGSGVVAIAAKMAGAKRVICCDIDETSLNACRENALLNNVE  137
            QWL  +   +  K V+DFG GSG++AIAA   GA + I  DID  ++ A R+NA  N V 
Sbjct  150  QWL--DSLDLTGKTVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVS  207

Query  138  LEYLNDLYLSESVDILLAADVL  159
                 +LYL +     + ADV+
Sbjct  208  DRL--ELYLPKDQPEEMKADVV  227


>P45558 Ribosomal protein L11 methyltransferase [Clostridium acetobutylicum 
(strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 
/ VKM B-1787)]
Length=311

 Score = 50.4 bits (119),  Expect = 8e-11
 Identities = 29/91 (32%), Positives = 53/91 (58%), Gaps = 5/91 (5%)

Query  88   KDKVVLDFGAGSGVVAIAAKMAGAKRVICCDIDETSLNACRENAL---LNNVELEYLNDL  144
            +D  V D G GSG++AIAA    AK+V+  D+D  ++ A +EN     +NN+E+ + N +
Sbjct  176  EDAEVFDIGTGSGILAIAAAKLNAKKVLGVDLDSVAVKAAKENIQYNNVNNIEILHGNLM  235

Query  145  YLSESVDILLAADVLYDQSNRFF--LDEFLK  173
             + +    ++ A+++ D  N     +++FLK
Sbjct  236  EVVQGKADIIVANIIADVINILIPDINKFLK  266


>O86951 Ribosomal protein L11 methyltransferase [Thermotoga neapolitana]
Length=264

 Score = 46.6 bits (109),  Expect = 1e-09
 Identities = 22/57 (39%), Positives = 34/57 (60%), Gaps = 0/57 (0%)

Query  92   VLDFGAGSGVVAIAAKMAGAKRVICCDIDETSLNACRENALLNNVELEYLNDLYLSE  148
            V+D G G+G++AI AK  GA  V+  D+DE ++   +EN   N+V++       LSE
Sbjct  133  VVDVGCGTGILAIVAKKLGASYVLAVDVDEQAVEVAKENVQKNSVDVTVKRSDLLSE  189


>G2K044 Ribosomal protein L11 methyltransferase [Listeria monocytogenes 
serotype 1/2a (strain 10403S)]
Length=314

 Score = 46.6 bits (109),  Expect = 2e-09
 Identities = 21/46 (46%), Positives = 29/46 (63%), Gaps = 0/46 (0%)

Query  92   VLDFGAGSGVVAIAAKMAGAKRVICCDIDETSLNACRENALLNNVE  137
            V+D G GSGV++IA+   GAK ++  D+DE +  A  EN  LN  E
Sbjct  178  VIDVGTGSGVLSIASAKLGAKSILATDLDEIATRAAEENITLNKTE  223


>O70467 Protein arginine N-methyltransferase 3 [Rattus norvegicus]
Length=528

 Score = 45.8 bits (107),  Expect = 4e-09
 Identities = 25/63 (40%), Positives = 38/63 (60%), Gaps = 3/63 (5%)

Query  79   WLLAEPHHVKDKVVLDFGAGSGVVAIAAKMAGAKRVICCDIDE---TSLNACRENALLNN  135
            ++   PH  KDKVVLD G G+G++++ A  AGAK+VI  D  E    +++  R N L + 
Sbjct  243  FIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVIAVDQSEILYQAMDIIRLNKLEDT  302

Query  136  VEL  138
            + L
Sbjct  303  IVL  305


>O60678 Protein arginine N-methyltransferase 3 [Homo sapiens]
Length=531

 Score = 45.8 bits (107),  Expect = 4e-09
 Identities = 28/83 (34%), Positives = 50/83 (60%), Gaps = 6/83 (7%)

Query  79   WLLAEPHHVKDKVVLDFGAGSGVVAIAAKMAGAKRVICCDIDE---TSLNACRENALLNN  135
            ++   PH  KDKVVLD G G+G++++ A  AGAK+V+  D  E    +++  R N L + 
Sbjct  246  FIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDT  305

Query  136  VEL--EYLNDLYLS-ESVDILLA  155
            + L    + +++L  E VD++++
Sbjct  306  ITLIKGKIEEVHLPVEKVDVIIS  328


>Q9MAT5 Protein arginine N-methyltransferase PRMT10 [Arabidopsis 
thaliana]
Length=383

 Score = 44.7 bits (104),  Expect = 8e-09
 Identities = 33/111 (30%), Positives = 57/111 (51%), Gaps = 6/111 (5%)

Query  85   HHVKDKVVLDFGAGSGVVAIAAKMAGAKRVICCDIDETSLNA---CRENALLNNVEL--E  139
            HH + K VLD G GSG++AI +  AGA++V   +  + + +A    + N L + VE+   
Sbjct  67   HHFEGKTVLDVGTGSGILAIWSAQAGARKVYAVEATKMADHARALVKANNLDHIVEVIEG  126

Query  140  YLNDLYLSESVDILLAADVLYDQSNRFFLDEFLKFAPEVWVADSRVKNFSH  190
             + D+ L E VD++++  + Y        D  +  A + W+  + V   SH
Sbjct  127  SVEDISLPEKVDVIISEWMGYFLLRESMFDSVIS-ARDRWLKPTGVMYPSH  176


>P0A0P5 Ribosomal protein L11 methyltransferase [Staphylococcus 
aureus]
Length=312

 Score = 44.3 bits (103),  Expect = 1e-08
 Identities = 19/46 (41%), Positives = 31/46 (67%), Gaps = 0/46 (0%)

Query  92   VLDFGAGSGVVAIAAKMAGAKRVICCDIDETSLNACRENALLNNVE  137
            V+D G GSG+++IA+ + G KR+   DIDE +++  +EN   N+ E
Sbjct  177  VIDVGTGSGILSIASHLIGVKRIKALDIDEMAVSVAKENFRRNHCE  222


 Score = 18.5 bits (36),  Expect = 2.5
 Identities = 17/57 (30%), Positives = 27/57 (47%), Gaps = 10/57 (18%)

Query  140  YLNDLYLSESV-----DILLAADVLYDQSNRFFLDEFLKFAPEVWVADSRVKNFSHP  191
            Y N++   + +     D LL  D L DQ N  F ++ +  A   W  ++  KN+ HP
Sbjct  67   YFNEMTYDDKLRQQIKDELLNLDEL-DQHNIQFSEQII--AETDW--ENEWKNYFHP  118



Lambda      K        H        a         alpha
   0.325    0.138    0.441    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 879427


  Database: c66eea961834533ddabd13d0a78696f8.SwissProt.fasta
    Posted date:  May 20, 2024  4:39 PM
  Number of letters in database: 5,705
  Number of sequences in database:  18



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40