BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: c02d821aea9ffe7a1208fb2569e8c9b6.SwissProt.fasta
           19 sequences; 5,835 total letters



Query= ACIAD3129

Length=310
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

P76250 HTH-type transcriptional regulator DmlR [Escherichia coli ...  177     4e-57
P43011 Uncharacterized HTH-type transcriptional regulator HI_1364...  155     6e-49
Q8XBK9 HTH-type transcriptional activator TtdR [Escherichia coli ...  150     9e-47
Q1R6S1 HTH-type transcriptional activator TtdR [Escherichia coli ...  149     5e-46
Q8FDH0 HTH-type transcriptional activator TtdR [Escherichia coli ...  149     5e-46
P45463 HTH-type transcriptional activator TtdR [Escherichia coli ...  149     5e-46
Q0TD46 HTH-type transcriptional activator TtdR [Escherichia coli ...  148     1e-45
P37641 Uncharacterized HTH-type transcriptional regulator YhjC [E...  137     1e-41
P30864 Uncharacterized HTH-type transcriptional regulator YafC [E...  134     1e-40
P67663 HTH-type transcriptional activator AaeR [Escherichia coli ...  134     1e-40
P67664 HTH-type transcriptional activator AaeR [Escherichia coli ...  134     1e-40
P67662 HTH-type transcriptional activator AaeR [Escherichia coli ...  134     1e-40
P75836 Uncharacterized HTH-type transcriptional regulator YcaN [E...  125     3e-37
P72131 HTH-type transcriptional regulator PtxR [Pseudomonas aerug...  124     1e-36
P52689 Probable HTH-type transcriptional regulator LtrA [Klebsiel...  121     2e-35
P37459 Probable HTH-type transcriptional regulator SinR [Salmonel...  119     1e-34
Q01610 Putative transcriptional regulator [Pseudomonas aeruginosa...  117     3e-34
A0A0H2ZDG9 HTH-type transcriptional repressor PA14_22550 [Pseudom...  107     3e-30
P77333 HTH-type transcriptional regulator PgrR [Escherichia coli ...  99.4    2e-27


>P76250 HTH-type transcriptional regulator DmlR [Escherichia coli 
(strain K12)]
Length=307

 Score = 177 bits (450),  Expect = 4e-57
 Identities = 94/295 (32%), Positives = 167/295 (57%), Gaps = 2/295 (1%)

Query  9    DDFQFFIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDEGRK  68
            +D + F+ VA     +  A+E  +S +  S+RI  LE TL + L +RTTR++T+T+EG +
Sbjct  8    NDLRVFMLVARRAGFAAVAEELGVSPAFVSKRIALLEQTLNVVLLHRTTRRVTITEEGER  67

Query  69   LLDFGRYWLDDFITLKDTLTARDKPLTGNLRVTTSATFGIKILTKVIANFALLHPTLNIY  128
            + ++ +  L D   + D L+   +   G LR+ +S  FG +++   +   A  +P L + 
Sbjct  68   IYEWAQRILQDVGQMMDELSDVRQVPQGMLRIISSFGFGRQVVAPALLALAKAYPQLELR  127

Query  129  LDLNDQNIDLIEHGMDLAIRIGKLNDSSLVAKPLMTNHRLICAAPSYLNQYGMPHSIEDL  188
             D+ D+ +DL+  G+DL IRIG     +L+A+ L TN+R++CA+P ++ Q+G P  + DL
Sbjct  128  FDVEDRLVDLVNEGVDLDIRIGDDIAPNLIARKLATNYRILCASPEFIAQHGAPKHLTDL  187

Query  189  QQHRCILQQHQNGLTDHWQLIDQKRTVVDVHLKAYFTTNSGEAIRQAALQGLGISNHSRW  248
                C++ + ++     WQL   K     + +    ++N GE + Q  L G GI+  S W
Sbjct  188  SALPCLVIKERDHPFGVWQL-RNKEGPHAIKVTGPLSSNHGEIVHQWCLDGQGIALRSWW  246

Query  249  HVADDLEQGHLIELLPEYQIEPTTIYAVFPNRQFRQPKTELFLSYLQNYFKHEYP  303
             V++++  GHL+++LPEY  +P  ++AV+ +R     K  + + +L+ YF   YP
Sbjct  247  DVSENIASGHLVQVLPEY-YQPANVWAVYVSRLATSAKVRITVEFLRQYFAEHYP  300


>P43011 Uncharacterized HTH-type transcriptional regulator HI_1364 
[Haemophilus influenzae (strain ATCC 51907 / DSM 11121 
/ KW20 / Rd)]
Length=288

 Score = 155 bits (393),  Expect = 6e-49
 Identities = 92/268 (34%), Positives = 149/268 (56%), Gaps = 2/268 (1%)

Query  14   FIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDEGRKLLDFG  73
            F +V +  S + AA++ NISV++AS+ + +LE  LK RL  RTTRKI  T+ G       
Sbjct  10   FCKVIETQSFTLAAKQQNISVAMASKLVSQLEEHLKTRLLQRTTRKIMPTEAGMMYYQRC  69

Query  74   RYWLDDFITLKDTLTARDKPLTGNLRVTTSATFGIKILTKVIANFALLHPTLNIYLDLND  133
            +  L D      ++T     L GNL ++    FG+  +   +  F   HP L+I ++ ND
Sbjct  70   QGILLDLDEADSSITQLTSSLQGNLLISVPRDFGLLFIAPNLPTFMAKHPHLHIEVEFND  129

Query  134  QNIDLIEHGMDLAIRIGKLNDSSLVAKPLMTNHRLICAAPSYLNQYGMPHSIEDLQQHRC  193
            + IDL+  G DLA+RIG + DSSLV++ + T      A+P+YL   G+P + +DL+ H  
Sbjct  130  KKIDLLSEGYDLALRIGYMEDSSLVSRKIGTTTVHFAASPNYLETNGIPQTPDDLEHHNG  189

Query  194  ILQQHQNGLTDHWQLIDQKRTVVDVHLKAYFTTNSGEAIRQAALQGLGISNHSRWHVADD  253
            +L  ++N +     +  +        +++   +NSG A+   A  GLGI+N  ++ +   
Sbjct  190  LL--YKNAMNQVNWVGSRINQTQRFKIQSKVVSNSGFALLNMAKAGLGIANLPKFILGRA  247

Query  254  LEQGHLIELLPEYQIEPTTIYAVFPNRQ  281
             E+G LIE+LPEY+ +   I+ V+PNR+
Sbjct  248  FEKGELIEILPEYKQQKLEIHVVYPNRR  275


>Q8XBK9 HTH-type transcriptional activator TtdR [Escherichia coli 
O157:H7]
Length=310

 Score = 150 bits (380),  Expect = 9e-47
 Identities = 89/285 (31%), Positives = 145/285 (51%), Gaps = 2/285 (1%)

Query  10   DFQFFIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDEGRKL  69
            D Q  + +   GS S AA     + +  ++RIQ LE+TL   L  R+ R + LT+ G++ 
Sbjct  10   DLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQILENTLATTLLNRSARGVALTESGQRC  69

Query  70   LDFGRYWLDDFITLKDTLTARDKPLTGNLRVTTSATFGIKILTKVIANFALLHPTLNIYL  129
             +     L  +  L D +T       G +R+  S  FG   +   I      +P L +Y 
Sbjct  70   YEHALEILTQYQRLVDDVTQIKTRPEGMIRIGCSFGFGRSHIAPAITELMRNYPELQVYF  129

Query  130  DLNDQNIDLIEHGMDLAIRIGKLNDSSLVAKPLMTNHRLICAAPSYLNQYGMPHSIEDLQ  189
            +L D+ IDL++  +DL IRI        +A  L  N R++CAAP YL +Y  P S+++L 
Sbjct  130  ELFDRQIDLVQDNIDLDIRINDEIPDYYIAHLLTKNKRILCAAPEYLQKYPQPQSLQELS  189

Query  190  QHRCILQQHQNGLTDHWQLIDQKRTVVDVHLKAYFTTNSGEAIRQAALQGLGISNHSRWH  249
            +H C++ + ++     W+L    +    V +  + ++NSGE + Q AL+G GI   S W 
Sbjct  190  RHDCLVTKERDMTHGIWEL-GNGQEKKSVKVSGHLSSNSGEIVLQWALEGKGIMLRSEWD  248

Query  250  VADDLEQGHLIELLPEYQIEPTTIYAVFPNRQFRQPKTELFLSYL  294
            V   LE G L+++LPEY  +   I+AV+    +R  K  + + +L
Sbjct  249  VLPFLESGKLVQVLPEY-AQSANIWAVYREPLYRSMKLRVCVEFL  292


>Q1R6S1 HTH-type transcriptional activator TtdR [Escherichia coli 
(strain UTI89 / UPEC)]
Length=310

 Score = 149 bits (375),  Expect = 5e-46
 Identities = 88/285 (31%), Positives = 144/285 (51%), Gaps = 2/285 (1%)

Query  10   DFQFFIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDEGRKL  69
            D Q  + +   GS S AA     + +  ++RIQ LE+TL   L  R+ R + LT+ G++ 
Sbjct  10   DLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQILENTLATTLLNRSARGVALTESGQRC  69

Query  70   LDFGRYWLDDFITLKDTLTARDKPLTGNLRVTTSATFGIKILTKVIANFALLHPTLNIYL  129
             +     L  +  L D +T       G +R+  S  FG   +   I      +P L ++ 
Sbjct  70   YEHALEILTQYQRLVDDVTQIKTRPEGMIRIGCSFGFGRSHIAPAITELMRNYPELQVHF  129

Query  130  DLNDQNIDLIEHGMDLAIRIGKLNDSSLVAKPLMTNHRLICAAPSYLNQYGMPHSIEDLQ  189
            +L D+ IDL++  +DL IRI        +A  L  N R++CAAP YL +Y  P S+++L 
Sbjct  130  ELFDRQIDLVQDNIDLDIRINDAIPDYYIAHLLTKNKRILCAAPEYLQKYPQPQSLQELS  189

Query  190  QHRCILQQHQNGLTDHWQLIDQKRTVVDVHLKAYFTTNSGEAIRQAALQGLGISNHSRWH  249
            +H C++ + ++     W+L    +    V +  + ++NSGE + Q AL+G GI   S W 
Sbjct  190  RHDCLVTKERDMTHGIWEL-GNGQEKKSVKVSGHLSSNSGEIVLQWALEGKGIMLRSEWD  248

Query  250  VADDLEQGHLIELLPEYQIEPTTIYAVFPNRQFRQPKTELFLSYL  294
            V   LE G L+ +LPEY  +   I+AV+    +R  K  + + +L
Sbjct  249  VLPFLESGKLVRVLPEY-AQSANIWAVYREPLYRSMKLRVCVEFL  292


>Q8FDH0 HTH-type transcriptional activator TtdR [Escherichia coli 
O6:H1 (strain CFT073 / ATCC 700928 / UPEC)]
Length=310

 Score = 149 bits (375),  Expect = 5e-46
 Identities = 88/285 (31%), Positives = 144/285 (51%), Gaps = 2/285 (1%)

Query  10   DFQFFIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDEGRKL  69
            D Q  + +   GS S AA     + +  ++RIQ LE+TL   L  R+ R + LT+ G++ 
Sbjct  10   DLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQILENTLATTLLNRSARGVALTESGQRC  69

Query  70   LDFGRYWLDDFITLKDTLTARDKPLTGNLRVTTSATFGIKILTKVIANFALLHPTLNIYL  129
             +     L  +  L D +T       G +R+  S  FG   +   I      +P L ++ 
Sbjct  70   YEHALEILTQYQRLVDDVTQIKTRPEGMIRIGCSFGFGRSHIAPAITELMRNYPELQVHF  129

Query  130  DLNDQNIDLIEHGMDLAIRIGKLNDSSLVAKPLMTNHRLICAAPSYLNQYGMPHSIEDLQ  189
            +L D+ IDL++  +DL IRI        +A  L  N R++CAAP YL +Y  P S+++L 
Sbjct  130  ELFDRQIDLVQDNIDLDIRINDAIPDYYIAHLLTKNKRILCAAPEYLQKYPQPQSLQELS  189

Query  190  QHRCILQQHQNGLTDHWQLIDQKRTVVDVHLKAYFTTNSGEAIRQAALQGLGISNHSRWH  249
            +H C++ + ++     W+L    +    V +  + ++NSGE + Q AL+G GI   S W 
Sbjct  190  RHDCLVTKERDMTHGIWEL-GNGQEKKSVKVSGHLSSNSGEIVLQWALEGKGIMLRSEWD  248

Query  250  VADDLEQGHLIELLPEYQIEPTTIYAVFPNRQFRQPKTELFLSYL  294
            V   LE G L+ +LPEY  +   I+AV+    +R  K  + + +L
Sbjct  249  VLPFLESGKLVRVLPEY-AQSANIWAVYREPLYRSMKLRVCVEFL  292


>P45463 HTH-type transcriptional activator TtdR [Escherichia coli 
(strain K12)]
Length=310

 Score = 149 bits (375),  Expect = 5e-46
 Identities = 88/285 (31%), Positives = 145/285 (51%), Gaps = 2/285 (1%)

Query  10   DFQFFIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDEGRKL  69
            D Q  + +   GS S AA     + +  ++RIQ LE+TL   L  R+ R + LT+ G++ 
Sbjct  10   DLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQILENTLATTLLNRSARGVALTESGQRC  69

Query  70   LDFGRYWLDDFITLKDTLTARDKPLTGNLRVTTSATFGIKILTKVIANFALLHPTLNIYL  129
             +     L  +  L D +T       G +R+  S  FG   +   I      +P L ++ 
Sbjct  70   YEHALEILTQYQRLVDDVTQIKTRPEGMIRIGCSFGFGRSHIAPAITELMRNYPELQVHF  129

Query  130  DLNDQNIDLIEHGMDLAIRIGKLNDSSLVAKPLMTNHRLICAAPSYLNQYGMPHSIEDLQ  189
            +L D+ IDL++  +DL IRI        +A  L  N R++CAAP YL +Y  P S+++L 
Sbjct  130  ELFDRQIDLVQDNIDLDIRINDEIPDYYIAHLLTKNKRILCAAPEYLQKYPQPQSLQELS  189

Query  190  QHRCILQQHQNGLTDHWQLIDQKRTVVDVHLKAYFTTNSGEAIRQAALQGLGISNHSRWH  249
            +H C++ + ++     W+L    +    V +  + ++NSGE + Q AL+G GI   S W 
Sbjct  190  RHDCLVTKERDMTHGIWEL-GNGQEKKSVKVSGHLSSNSGEIVLQWALEGKGIMLRSEWD  248

Query  250  VADDLEQGHLIELLPEYQIEPTTIYAVFPNRQFRQPKTELFLSYL  294
            V   LE G L+++LPEY  +   I+AV+    +R  K  + + +L
Sbjct  249  VLPFLESGKLVQVLPEY-AQSANIWAVYREPLYRSMKLRVCVEFL  292


>Q0TD46 HTH-type transcriptional activator TtdR [Escherichia coli 
O6:K15:H31 (strain 536 / UPEC)]
Length=310

 Score = 148 bits (373),  Expect = 1e-45
 Identities = 88/285 (31%), Positives = 144/285 (51%), Gaps = 2/285 (1%)

Query  10   DFQFFIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDEGRKL  69
            D Q  + +   GS S AA     + +  ++RIQ LE+TL   L  R+ R + LT+ G++ 
Sbjct  10   DLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQILENTLATTLLNRSARGVALTESGQRC  69

Query  70   LDFGRYWLDDFITLKDTLTARDKPLTGNLRVTTSATFGIKILTKVIANFALLHPTLNIYL  129
             +     L  +  L D +T       G +R+  S  FG   +   I      +P L ++ 
Sbjct  70   YEHALEILTQYQRLVDDVTQIKTRPEGMIRIGCSFGFGRSHIAPAITELMRNYPELQVHF  129

Query  130  DLNDQNIDLIEHGMDLAIRIGKLNDSSLVAKPLMTNHRLICAAPSYLNQYGMPHSIEDLQ  189
            +L D+ IDL++  +DL IRI        +A  L  N R++CAAP YL +Y  P S+++L 
Sbjct  130  ELFDRQIDLVQDNIDLDIRINDEIPDYYIAHLLTKNKRILCAAPEYLQKYPQPQSLQELS  189

Query  190  QHRCILQQHQNGLTDHWQLIDQKRTVVDVHLKAYFTTNSGEAIRQAALQGLGISNHSRWH  249
            +H C++ + ++     W+L    +    V +  + ++NSGE + Q AL+G GI   S W 
Sbjct  190  RHDCLVTKERDMTHGIWEL-GNGQEKKSVKVSGHLSSNSGEIVLQWALEGKGIMLRSEWD  248

Query  250  VADDLEQGHLIELLPEYQIEPTTIYAVFPNRQFRQPKTELFLSYL  294
            V   LE G L+ +LPEY  +   I+AV+    +R  K  + + +L
Sbjct  249  VLPFLESGKLVRVLPEY-AQSANIWAVYREPLYRSMKLRVCVEFL  292


>P37641 Uncharacterized HTH-type transcriptional regulator YhjC 
[Escherichia coli (strain K12)]
Length=299

 Score = 137 bits (345),  Expect = 1e-41
 Identities = 88/288 (31%), Positives = 134/288 (47%), Gaps = 0/288 (0%)

Query  12   QFFIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDEGRKLLD  71
            Q FI+VA+  S S+AA    +     S++IQ LE  L  +L  RTTR++ LT EG     
Sbjct  8    QLFIKVAELESFSRAADFFALPKGSVSRQIQALEHQLGTQLLQRTTRRVKLTPEGMTYYQ  67

Query  72   FGRYWLDDFITLKDTLTARDKPLTGNLRVTTSATFGIKILTKVIANFALLHPTLNIYLDL  131
              +  L +   L          ++G LR+         +L   ++ F  LHP + + L  
Sbjct  68   RAKDVLSNLSELDGLFQQDATSISGKLRIDIPPGIAKSLLLPRLSEFLYLHPGIELELSS  127

Query  132  NDQNIDLIEHGMDLAIRIGKLNDSSLVAKPLMTNHRLICAAPSYLNQYGMPHSIEDLQQH  191
            +D+ +D++  G D  IR G L +  ++A+PL     + CA+P YL ++G P S +DL  H
Sbjct  128  HDRPVDILHDGFDCVIRTGALPEDGVIARPLGKLTMVNCASPHYLTRFGYPQSPDDLTSH  187

Query  192  RCILQQHQNGLTDHWQLIDQKRTVVDVHLKAYFTTNSGEAIRQAALQGLGISNHSRWHVA  251
              +      G+      +     V         T NS E    A L GLGI    R  V 
Sbjct  188  AIVRYTPHLGVHPLGFEVASVNGVQWFKSGGMLTVNSSENYLTAGLAGLGIIQIPRIAVR  247

Query  252  DDLEQGHLIELLPEYQIEPTTIYAVFPNRQFRQPKTELFLSYLQNYFK  299
            + L  G LIE+LP Y+ EP ++  V+P R+    +  LF+ +L    K
Sbjct  248  EALRAGRLIEVLPGYRAEPLSLSLVYPQRRELSRRVNLFMQWLAGVMK  295


>P30864 Uncharacterized HTH-type transcriptional regulator YafC 
[Escherichia coli (strain K12)]
Length=304

 Score = 134 bits (338),  Expect = 1e-40
 Identities = 85/294 (29%), Positives = 158/294 (54%), Gaps = 6/294 (2%)

Query  8    TDDFQFFIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDEGR  67
            +++   F+ V + GS S+AA++   + S  S+ +++LE  L + L  RTTR+++LT+EG 
Sbjct  5    SEELAIFVSVVESGSFSRAAEQLGQANSAVSRAVKKLEMKLGVSLLNRTTRQLSLTEEGE  64

Query  68   KLLDFGRYWLDDFITLKDTLTARDKPLTGNLRVTTSATFGIKILTKVIANFALLHPTLNI  127
            +     +  L +    +  +        G LR+  +    +  L  +I  F   +P + +
Sbjct  65   RYFRRVQSILQEMAAAESEIMETRNTPRGLLRIDAATPVVLHFLMPLIKPFRERYPEVTL  124

Query  128  YLDLNDQNIDLIEHGMDLAIRIGKLNDSSLVAKPLMTNHRLICAAPSYLNQYGMPHSIED  187
             L  ++  I+LIE  +D+AIR G L DSSL A+PL  ++R I A+P Y+++YG P +I+D
Sbjct  125  SLVSSETIINLIERKVDVAIRAGTLTDSSLRARPLFNSYRKIIASPDYISRYGKPETIDD  184

Query  188  LQQHRCILQQHQNGLTDHWQLIDQKRTVVDVHLKAYFTTNSGEAIRQAALQGLGISNHSR  247
            L+QH C+       L + W +      + +V  K   ++NSGE ++Q  L G GI+  S 
Sbjct  185  LKQHICLGFTEPASL-NTWPIARSDGQLHEV--KYGLSSNSGETLKQLCLSGNGIACLSD  241

Query  248  WHVADDLEQGHLIELLPEYQIEPTTI--YAVFPNRQFRQPKTELFLSYLQNYFK  299
            + +  ++ +G L+EL+ + ++ P  +   AV+ + +    +   F+ +L  + K
Sbjct  242  YMIDKEIARGELVELMAD-KVLPVEMPFSAVYYSDRAVSTRIRAFIDFLSEHVK  294


>P67663 HTH-type transcriptional activator AaeR [Escherichia coli 
O6:H1 (strain CFT073 / ATCC 700928 / UPEC)]
Length=309

 Score = 134 bits (338),  Expect = 1e-40
 Identities = 87/285 (31%), Positives = 145/285 (51%), Gaps = 2/285 (1%)

Query  14   FIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDEGRKLLDFG  73
            F +V + GS + AA++  +SVS  SQ + +LE  L+++L  R+TR I LT+ GR      
Sbjct  10   FAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTEAGRIYYQGC  69

Query  74   RYWLDDFITLKDTLTARDKPLTGNLRVTTSATFGIKILTKVIANFALLHPTLNIYLDLND  133
            R  L +   + + L A +    G LR+  S+T    +L  + A     +P L++ L    
Sbjct  70   RRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPGLSVNLVTGI  129

Query  134  QNIDLIEHGMDLAIRIGKLNDSSLVAKPLMTNHRLICAAPSYLNQYGMPHSIEDLQQHRC  193
               DLI  G+D+ IR+G L DSSL ++ L     ++CAA SYL QYG+P    DL  H  
Sbjct  130  PAPDLIADGLDVVIRVGALQDSSLFSRRLGAMPMVVCAAKSYLTQYGIPEKPADLSSHSW  189

Query  194  ILQQHQNGLTDHWQLIDQKRTVVDVHLKAYFTTNSGEAIRQAALQGLGISNHSRWHVADD  253
            +  ++     + ++LI  +     +  +  F TN    + +    G GI+      V ++
Sbjct  190  L--EYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVPLMWVINE  247

Query  254  LEQGHLIELLPEYQIEPTTIYAVFPNRQFRQPKTELFLSYLQNYF  298
            + +G L  LLP YQ +P  +YA++  +     K ++ ++ L +YF
Sbjct  248  INRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYF  292


>P67664 HTH-type transcriptional activator AaeR [Escherichia coli 
O157:H7]
Length=309

 Score = 134 bits (338),  Expect = 1e-40
 Identities = 87/285 (31%), Positives = 145/285 (51%), Gaps = 2/285 (1%)

Query  14   FIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDEGRKLLDFG  73
            F +V + GS + AA++  +SVS  SQ + +LE  L+++L  R+TR I LT+ GR      
Sbjct  10   FAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTEAGRIYYQGC  69

Query  74   RYWLDDFITLKDTLTARDKPLTGNLRVTTSATFGIKILTKVIANFALLHPTLNIYLDLND  133
            R  L +   + + L A +    G LR+  S+T    +L  + A     +P L++ L    
Sbjct  70   RRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPGLSVNLVTGI  129

Query  134  QNIDLIEHGMDLAIRIGKLNDSSLVAKPLMTNHRLICAAPSYLNQYGMPHSIEDLQQHRC  193
               DLI  G+D+ IR+G L DSSL ++ L     ++CAA SYL QYG+P    DL  H  
Sbjct  130  PAPDLIADGLDVVIRVGALQDSSLFSRRLGAMPMVVCAAKSYLTQYGIPEKPADLSSHSW  189

Query  194  ILQQHQNGLTDHWQLIDQKRTVVDVHLKAYFTTNSGEAIRQAALQGLGISNHSRWHVADD  253
            +  ++     + ++LI  +     +  +  F TN    + +    G GI+      V ++
Sbjct  190  L--EYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVPLMWVINE  247

Query  254  LEQGHLIELLPEYQIEPTTIYAVFPNRQFRQPKTELFLSYLQNYF  298
            + +G L  LLP YQ +P  +YA++  +     K ++ ++ L +YF
Sbjct  248  INRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYF  292


>P67662 HTH-type transcriptional activator AaeR [Escherichia coli 
(strain K12)]
Length=309

 Score = 134 bits (338),  Expect = 1e-40
 Identities = 87/285 (31%), Positives = 145/285 (51%), Gaps = 2/285 (1%)

Query  14   FIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDEGRKLLDFG  73
            F +V + GS + AA++  +SVS  SQ + +LE  L+++L  R+TR I LT+ GR      
Sbjct  10   FAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTEAGRIYYQGC  69

Query  74   RYWLDDFITLKDTLTARDKPLTGNLRVTTSATFGIKILTKVIANFALLHPTLNIYLDLND  133
            R  L +   + + L A +    G LR+  S+T    +L  + A     +P L++ L    
Sbjct  70   RRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPGLSVNLVTGI  129

Query  134  QNIDLIEHGMDLAIRIGKLNDSSLVAKPLMTNHRLICAAPSYLNQYGMPHSIEDLQQHRC  193
               DLI  G+D+ IR+G L DSSL ++ L     ++CAA SYL QYG+P    DL  H  
Sbjct  130  PAPDLIADGLDVVIRVGALQDSSLFSRRLGAMPMVVCAAKSYLTQYGIPEKPADLSSHSW  189

Query  194  ILQQHQNGLTDHWQLIDQKRTVVDVHLKAYFTTNSGEAIRQAALQGLGISNHSRWHVADD  253
            +  ++     + ++LI  +     +  +  F TN    + +    G GI+      V ++
Sbjct  190  L--EYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVPLMWVINE  247

Query  254  LEQGHLIELLPEYQIEPTTIYAVFPNRQFRQPKTELFLSYLQNYF  298
            + +G L  LLP YQ +P  +YA++  +     K ++ ++ L +YF
Sbjct  248  INRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYF  292


>P75836 Uncharacterized HTH-type transcriptional regulator YcaN 
[Escherichia coli (strain K12)]
Length=302

 Score = 125 bits (315),  Expect = 3e-37
 Identities = 77/291 (26%), Positives = 135/291 (46%), Gaps = 5/291 (2%)

Query  6    MNTDDFQFFIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDE  65
            MN  DF  F  VA   S   A  E  +S S  S  I+ LE  LK+RLF RTTR ++LT+ 
Sbjct  3    MNMSDFATFFAVARNQSFRAAGDELGLSSSAISHSIKTLEQRLKIRLFNRTTRSVSLTEA  62

Query  66   GRKLLDFGRYWLDDFITLKDTLTARDKPLTGNLRVTTSATFGIKILTKVIANFALLHPTL  125
            G  L +  R   D+   + D +       TG L++  +       L  ++  F   +P +
Sbjct  63   GSNLYERLRPAFDEIQIMLDEMNDFRLTPTGTLKINAARVAARIFLMSLLVGFTREYPDI  122

Query  126  NIYLDLNDQNIDLIEHGMDLAIRIGKLNDSSLVAKPLMTNHRL-ICAAPSYLNQYGMPHS  184
             + L  +D  +D+++ G D  +R+  + +  +++  +    +L + A P Y  +YG P  
Sbjct  123  KVELTTDDSLVDIVQQGFDAGVRLSCIVEKDMISVAIGPPVKLCVAATPEYFARYGKPRH  182

Query  185  IEDLQQHRCILQQHQNGLTDHWQLIDQKRTVVDVHLKAYFTTNSGEAIRQAALQGLGISN  244
              DL  H+C++ ++ +G   HWQ   +    +++ +      +  +A  +A L G GI  
Sbjct  183  PHDLLNHQCVVFRYPSGKPFHWQFAKE----LEIAVAGNIILDDVDAELEAVLMGAGIGY  238

Query  245  HSRWHVADDLEQGHLIELLPEYQIEPTTIYAVFPNRQFRQPKTELFLSYLQ  295
                 + + L+ G L  +L ++  E       +PNRQ+       FL Y++
Sbjct  239  LLYEQIKEYLDTGRLECVLEDWSTERPGFQIYYPNRQYMSCGLRAFLDYVK  289


 Score = 17.3 bits (33),  Expect = 8.7
 Identities = 17/71 (24%), Positives = 30/71 (42%), Gaps = 5/71 (7%)

Query  233  RQAALQGLGISNHSRWHVADDLEQGHLIELLPEYQIEPTTIYAVFPNRQFRQPKTELFLS  292
            R  +L   G + + R   A D E   +++ + ++++ PT    +   R        +FL 
Sbjct  55   RSVSLTEAGSNLYERLRPAFD-EIQIMLDEMNDFRLTPTGTLKINAARV----AARIFLM  109

Query  293  YLQNYFKHEYP  303
             L   F  EYP
Sbjct  110  SLLVGFTREYP  120


>P72131 HTH-type transcriptional regulator PtxR [Pseudomonas aeruginosa 
(strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 
14847 / LMG 12228 / 1C / PRS 101 / PAO1)]
Length=312

 Score = 124 bits (311),  Expect = 1e-36
 Identities = 85/297 (29%), Positives = 147/297 (49%), Gaps = 4/297 (1%)

Query  6    MNTDDFQFFIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDE  65
            +N +    F+ VA+  S + AA+   +S S+ S++++RLE+ L ++L  RTTR++TLTD 
Sbjct  11   LNLNHLYAFVAVAEHNSFTAAAEALGLSKSLLSEQLRRLEADLGIQLLTRTTRRMTLTDR  70

Query  66   GRKLLDFGRYWLDDFI-TLKDTLTARDKPLTGNLRVTTSATFGIKILTKVIANFALLHPT  124
            G  L    +  L +    L D    + +P +G LR+T    F    ++ V A F    P 
Sbjct  71   GELLFGVAQRMLGELDGALSDVRDLQGEP-SGRLRITAPQDFVKWHISSVSAAFIRQFPK  129

Query  125  LNIYLDLNDQNIDLIEHGMDLAIRIGKLNDSSLVAKPLMTNHRLICAAPSYLNQYGMPHS  184
            + + +  +DQ  DL+   +DLA+RIG   DS L A  L    ++  A P YL   G+P  
Sbjct  130  VQVEMLADDQFSDLVGQRIDLAVRIGWPRDSGLHASKLCDFQQVAVATPGYL--AGLPPV  187

Query  185  IEDLQQHRCILQQHQNGLTDHWQLIDQKRTVVDVHLKAYFTTNSGEAIRQAALQGLGISN  244
            ++     RC    H    T      +++R    V  +     N+  A+ +  L G G+S 
Sbjct  188  LQPHDLARCEWIGHTRLSTPWTWTFERQRERATVQTRGRLLANNTLAVYRLVLDGAGVSV  247

Query  245  HSRWHVADDLEQGHLIELLPEYQIEPTTIYAVFPNRQFRQPKTELFLSYLQNYFKHE  301
               + VA ++ +G L+ LLP +++    IYA++P+ ++   +   F+  L+ +   E
Sbjct  248  LPSFLVAREIARGRLVRLLPGWRLPQGGIYALYPSARYMPVRVRAFIESLREHLGRE  304


>P52689 Probable HTH-type transcriptional regulator LtrA [Klebsiella 
pneumoniae]
Length=309

 Score = 121 bits (303),  Expect = 2e-35
 Identities = 73/258 (28%), Positives = 126/258 (49%), Gaps = 2/258 (1%)

Query  10   DFQFFIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDEGRKL  69
            D   F+++ D GS S  A++  I+ S  S+ + RLE  +  +L  RTTRK+ L+D G  +
Sbjct  8    DLALFVQIVDQGSFSAVARQNGITPSAVSRSVSRLEREMGCKLLQRTTRKLRLSDAGETI  67

Query  70   LDFGRYWLDDFITLKDTLTARDKPLTGNLRVTTSATFGIKILTKVIANFALLHPTLNIYL  129
                +  L+      D+  +R     G L ++     G  ++  ++  F   +P +++ L
Sbjct  68   YQHAQQMLEAARQAMDSAGSRQTVAQGKLTLSVPKAVGRFVIHPLMMAFFHRYPQVDVCL  127

Query  130  DLNDQNIDLIEHGMDLAIRIGKLNDSSLVAKPLMTNHRLICAAPSYLNQYGMPHSIEDLQ  189
             L D+ +D I+ G+DLA+RI       L  KPLM    +ICA  +YL Q+G P++ +DL+
Sbjct  128  RLEDRPLDFIDDGIDLALRITDTPSPGLHGKPLMPIRHVICATEAYLQQHGTPYTPQDLR  187

Query  190  QHRCILQQHQNGLTDHWQLIDQKRTVVDVHLKAYFTTNSGEAIRQAALQGLGISNHSRWH  249
             H CI    +      W+   + +T   V     +  N       A  Q LGI +   + 
Sbjct  188  AHSCI-SLGETPADARWKFRREGKTET-VQTYGRYAANHTAVRLDAVRQHLGIGSLPLFT  245

Query  250  VADDLEQGHLIELLPEYQ  267
              + L  G ++++LPE++
Sbjct  246  AREALANGDIVQVLPEWE  263


>P37459 Probable HTH-type transcriptional regulator SinR [Salmonella 
typhimurium (strain LT2 / SGSC1412 / ATCC 700720)]
Length=315

 Score = 119 bits (298),  Expect = 1e-34
 Identities = 86/307 (28%), Positives = 154/307 (50%), Gaps = 21/307 (7%)

Query  10   DFQFFIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDEGRKL  69
            D+  FI+VA+ G+LS+AA+E +IS+S  S+ + RLE+++++ L  R +  + LT  G+  
Sbjct  12   DWMIFIKVAEVGNLSRAARELDISISAVSKSLSRLENSIEVTLLRRDSHHLELTGAGQTA  71

Query  70   LDFGRYWLDDFITLKDTLTARDKPLTGNLRVTTSATFGIKILTKVIANFALLHPTLNIYL  129
                +     F +L D L   DK + G+++ +  A     +  K I  F   +P   IYL
Sbjct  72   YASMKRITSSFQSLLDELRNPDKIIRGSIKFSAPAIVCEFLANKWIWEFTASYPDTKIYL  131

Query  130  DLNDQNIDLIEHGM---DLAIRIGKLNDSSLVAKPLMTNHRLICAAPSYLNQYGMPHSIE  186
            D  +++ D     +   +L  + G +    LV + +     ++CA+P Y+ +YG      
Sbjct  132  DSRERS-DFFSKSLEFDELVFKSGIIESEDLVYRKISPLKLVLCASPKYIRKYGRISHPG  190

Query  187  DLQQHRCILQQHQNGLTDHWQLIDQKRT-----VVDVHLKAYFTTNSGEAIRQAALQGLG  241
            DL+ H  I+  H +GL+    L  Q  +      V+VHL    ++N+  ++    L+G G
Sbjct  191  DLENH-IIVGLHNHGLSGPLTLFRQDESYTISGAVNVHL----SSNNLLSVLNLVLEGKG  245

Query  242  ISNHS-RWHVADDLEQGHLIELLPEYQIEPTTIYAVFPNRQFRQPKTELFLSYLQNYFKH  300
            I+  +  W     L+   L  +LPE+++    IY V+ +RQ+  P  + FLS++++    
Sbjct  246  INLMTPAWLATKYLKNNELEIILPEWRVPDLPIYLVWRHRQYYSPLFQRFLSFIED----  301

Query  301  EYPWNIR  307
               WN R
Sbjct  302  --KWNNR  306


>Q01610 Putative transcriptional regulator [Pseudomonas aeruginosa 
(strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 
/ LMG 12228 / 1C / PRS 101 / PAO1)]
Length=306

 Score = 117 bits (294),  Expect = 3e-34
 Identities = 86/291 (30%), Positives = 140/291 (48%), Gaps = 3/291 (1%)

Query  7    NTDDFQFFIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDEG  66
            N +D   F+ VA  G+ ++AA +  ++ S  SQ I  LE+ L++RL  RTTR ++ T  G
Sbjct  5    NLNDLLSFVAVAREGTFTRAAAQLGVTQSALSQSISGLEARLQIRLLTRTTRSVSPTAAG  64

Query  67   RKLLDFGRYWLDDFITLKDTLTA-RDKPLTGNLRVTTSATFGIKILTKVIANFALLHPTL  125
             +LL+      D+     D L+A RDKP +G +R+T        +L   +    L +P +
Sbjct  65   ERLLNAIGNRFDEIEAELDELSALRDKP-SGTVRITCGDHIQRTLLLPRLTPLLLEYPDI  123

Query  126  NIYLDLNDQNIDLIEHGMDLAIRIGKLNDSSLVAKPLMTNHRL-ICAAPSYLNQYGMPHS  184
             +  D+N    D++    D  +R+G   D  ++A P+    R+ + AAP+Y   +  P S
Sbjct  124  KVEFDINYGFRDIVADRFDAGVRLGDTIDKDMIAVPIGPPVRMAVVAAPAYFAAHPKPRS  183

Query  185  IEDLQQHRCILQQHQNGLTDHWQLIDQKRTVVDVHLKAYFTTNSGEAIRQAALQGLGISN  244
              DL  H CI  + Q+G   +     +K   V+V +      N+   I  AAL GLGI+ 
Sbjct  184  PRDLVDHNCINMRMQSGGGLYAWDFQRKDRHVNVRVDGQLIFNTSPNIVDAALAGLGIAW  243

Query  245  HSRWHVADDLEQGHLIELLPEYQIEPTTIYAVFPNRQFRQPKTELFLSYLQ  295
                  A  +E+G L+ +L  +       Y  +PNR+   P   L +  L+
Sbjct  244  LPEEEFAPHIEEGRLLRVLENWCPLFPGYYLYYPNRRQPSPAFSLVVDALR  294


>A0A0H2ZDG9 HTH-type transcriptional repressor PA14_22550 [Pseudomonas 
aeruginosa (strain UCBPP-PA14)]
Length=317

 Score = 107 bits (267),  Expect = 3e-30
 Identities = 79/289 (27%), Positives = 135/289 (47%), Gaps = 8/289 (3%)

Query  14   FIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDEGRKLLDFG  73
            F++V D GS ++AA    +  +  SQR+  LE  L +RL  RTTR ++LT +G    D  
Sbjct  10   FVKVVDAGSFTRAADALGLPKARVSQRVSDLEKHLGVRLLNRTTRALSLTHDGSAYFDKC  69

Query  74   RYWLDDFITLKDTLTARDKPLTGNLRVTTSATFGIKILTKVIANFALLHPTLNIYLDLND  133
            +  L     L+ TL        G LRV +  T    ++   + +F   +P + + L  +D
Sbjct  70   QVLLQQIDELEATLRGGTATPIGRLRVDSLITIARWVIAPRLHDFQARYPRIQLRLSSSD  129

Query  134  QNIDLIEHGMDLAIRIGKLNDSSLVAKPLMTNHRLICAAPSYLNQYGMPHSIEDLQQHRC  193
            +  +L+E G+D  IR G L DSS++A+ L      + A+P YL   G   S  DL Q R 
Sbjct  130  RISNLLEDGIDCTIRGGALKDSSMIARHLCDIQMGLYASPEYLASIGGVDSPNDLSQFRR  189

Query  194  I---LQQHQNGLTDHWQL-IDQKRTVVDVHLKAYFTTNSGEAIRQAALQGLGISNHSRWH  249
            +     + +N     W+L    +R VV       F  +  +    A + G GI   + + 
Sbjct  190  LSWFSGRERNPFM--WELESGPERFVVQSGDGMQF--DEPDVAISACMAGSGICPGAPFA  245

Query  250  VADDLEQGHLIELLPEYQIEPTTIYAVFPNRQFRQPKTELFLSYLQNYF  298
            VA  +  G L+ +LP++      ++ ++P  +    +   F++++   F
Sbjct  246  VAGFVRAGKLVPVLPQWHFSAAPVHVIYPGSRHLSVRVRCFVNWVMELF  294


>P77333 HTH-type transcriptional regulator PgrR [Escherichia coli 
(strain K12)]
Length=299

 Score = 99.4 bits (246),  Expect = 2e-27
 Identities = 75/288 (26%), Positives = 136/288 (47%), Gaps = 3/288 (1%)

Query  10   DFQFFIRVADCGSLSKAAQEANISVSVASQRIQRLESTLKLRLFYRTTRKITLTDEGRKL  69
            D   F+ VA+  S ++AA   +++ S  SQ ++R+E  L LRL  RTTR +  T+ G  L
Sbjct  8    DLMAFVVVAEERSFTRAAARLSMAQSALSQIVRRIEERLGLRLLTRTTRSVVPTEAGEHL  67

Query  70   LDFGRYWLDDFITLKDTLTARDKPLTGNLRVTTSATFGIKILTKVIANFALLHPTLNIYL  129
            L      L D  +   +L+      +G +R+TT       IL   +  F   HP ++I L
Sbjct  68   LSVLGPMLHDIDSAMASLSDLQNRPSGTIRITTVEHAAKTILLPAMRTFLKSHPEIDIQL  127

Query  130  DLNDQNIDLIEHGMDLAIRIGKLNDSSLVAKPLMTNHRL-ICAAPSYLNQYGMPHSIEDL  188
             ++    D++    D  +R+G   D  ++A  +  +  + I  +P Y ++  +P S+  L
Sbjct  128  TIDYGLTDVVSERFDAGVRLGGEMDKDMIAIRIGPDIPMAIVGSPDYFSRRSVPTSVSQL  187

Query  189  QQHRCI-LQQHQNGLTDHWQLIDQKRTVVDVHLKAYFTTNSGEAIRQAALQGLGISNHSR  247
              H+ I L    +G  + W+LI   R  V V ++     N+ + I  AA+ G G++    
Sbjct  188  IDHQAINLYLPTSGTANRWRLIRGGRE-VRVRMEGQLLLNTIDLIIDAAIDGHGLAYLPY  246

Query  248  WHVADDLEQGHLIELLPEYQIEPTTIYAVFPNRQFRQPKTELFLSYLQ  295
              V   +++  LI +L ++  +    +  +P+R+       LF+  L+
Sbjct  247  DQVERAIKEKKLIRVLDKFTPDLPGYHLYYPHRRHAGSAFSLFIDRLK  294



Lambda      K        H        a         alpha
   0.325    0.139    0.416    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 1299746


  Database: c02d821aea9ffe7a1208fb2569e8c9b6.SwissProt.fasta
    Posted date:  Jun 3, 2024  3:27 AM
  Number of letters in database: 5,835
  Number of sequences in database:  19



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40