BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 1fbe0f24fc9ed02b9a4944d7c46fe3ee.SwissProt.fasta
19 sequences; 4,269 total letters
Query= ACIAD0865
Length=212
Score E
Sequences producing significant alignments: (Bits) Value
P0AFR6 Uncharacterized protein YciO [Shigella flexneri] 229 4e-80
P0AFR5 Uncharacterized protein YciO [Escherichia coli O6:H1 (stra... 229 4e-80
P0AFR4 Uncharacterized protein YciO [Escherichia coli (strain K12)] 229 4e-80
P45103 Uncharacterized protein HI_1198 [Haemophilus influenzae (s... 210 1e-72
Q7MGL3 Threonylcarbamoyl-AMP synthase [Vibrio vulnificus (strain ... 73.9 6e-20
Q8DDD6 Threonylcarbamoyl-AMP synthase [Vibrio vulnificus (strain ... 73.9 6e-20
Q3J7C4 Threonylcarbamoyl-AMP synthase [Nitrosococcus oceani (stra... 73.6 9e-20
A1WZH9 Threonylcarbamoyl-AMP synthase [Halorhodospira halophila (... 73.6 1e-19
Q6LLJ9 Threonylcarbamoyl-AMP synthase [Photobacterium profundum (... 70.9 9e-19
Q3IDH7 Threonylcarbamoyl-AMP synthase [Pseudoalteromonas transluc... 70.9 9e-19
P9WGC9 Putative threonylcarbamoyl-AMP synthase [Mycobacterium tub... 71.2 1e-18
P9WGC8 Putative threonylcarbamoyl-AMP synthase [Mycobacterium tub... 71.2 1e-18
Q48AU1 Threonylcarbamoyl-AMP synthase [Colwellia psychrerythraea ... 69.7 2e-18
Q83AA2 Threonylcarbamoyl-AMP synthase [Coxiella burnetii (strain ... 67.0 2e-17
P39153 Threonylcarbamoyl-AMP synthase [Bacillus subtilis (strain ... 68.2 5e-17
Q3U5F4 Threonylcarbamoyl-AMP synthase [Mus musculus] 62.8 3e-15
Q86U90 Threonylcarbamoyl-AMP synthase [Homo sapiens] 62.4 4e-15
P45748 Threonylcarbamoyl-AMP synthase [Escherichia coli (strain K... 57.8 6e-14
P32579 Threonylcarbamoyl-AMP synthase [Saccharomyces cerevisiae (... 38.1 8e-07
>P0AFR6 Uncharacterized protein YciO [Shigella flexneri]
Length=206
Score = 229 bits (583), Expect = 4e-80
Identities = 108/200 (54%), Positives = 150/200 (75%), Gaps = 0/200 (0%)
Query 11 HIHPDNPQARLINQAVERIRAGDVVVYPTDAAYSIGCQIGNKSAMERIAQIRGLGPKHQY 70
+IHPDNPQ RLINQAVE +R G V+VYPTD+ Y++GC+I +K+AMERI +IR L H +
Sbjct 6 YIHPDNPQQRLINQAVEIVRKGGVIVYPTDSGYALGCKIEDKNAMERICRIRQLPDGHNF 65
Query 71 AIMCCDLSDIATYAKVDNAMYRLLKANTPSITTFILPATSEVPKRLMHPKKKTIGLRIPT 130
+MC DLS+++TY+ VDN +RL+K NTP TFIL T EVP+RL+ K+KTIG+R+P+
Sbjct 66 TLMCRDLSELSTYSFVDNVAFRLMKNNTPGNYTFILKGTKEVPRRLLQEKRKTIGMRVPS 125
Query 131 NPICQALLQELGEPILTSTLILPGQSDPLDDPYDIENQLGKRVDVFIDGGFGTLSTTSIV 190
NPI QALL+ LGEP+L+++L+LPG DP +I+++L K+VD+ I GG+ T+++
Sbjct 126 NPIAQALLEALGEPMLSTSLMLPGSEFTESDPEEIKDRLEKQVDLIIHGGYLGQKPTTVI 185
Query 191 DLSGENPEVVRHGAGDVSAF 210
DL+ + P VVR G GDV F
Sbjct 186 DLTDDTPVVVREGVGDVKPF 205
>P0AFR5 Uncharacterized protein YciO [Escherichia coli O6:H1 (strain
CFT073 / ATCC 700928 / UPEC)]
Length=206
Score = 229 bits (583), Expect = 4e-80
Identities = 108/200 (54%), Positives = 150/200 (75%), Gaps = 0/200 (0%)
Query 11 HIHPDNPQARLINQAVERIRAGDVVVYPTDAAYSIGCQIGNKSAMERIAQIRGLGPKHQY 70
+IHPDNPQ RLINQAVE +R G V+VYPTD+ Y++GC+I +K+AMERI +IR L H +
Sbjct 6 YIHPDNPQQRLINQAVEIVRKGGVIVYPTDSGYALGCKIEDKNAMERICRIRQLPDGHNF 65
Query 71 AIMCCDLSDIATYAKVDNAMYRLLKANTPSITTFILPATSEVPKRLMHPKKKTIGLRIPT 130
+MC DLS+++TY+ VDN +RL+K NTP TFIL T EVP+RL+ K+KTIG+R+P+
Sbjct 66 TLMCRDLSELSTYSFVDNVAFRLMKNNTPGNYTFILKGTKEVPRRLLQEKRKTIGMRVPS 125
Query 131 NPICQALLQELGEPILTSTLILPGQSDPLDDPYDIENQLGKRVDVFIDGGFGTLSTTSIV 190
NPI QALL+ LGEP+L+++L+LPG DP +I+++L K+VD+ I GG+ T+++
Sbjct 126 NPIAQALLEALGEPMLSTSLMLPGSEFTESDPEEIKDRLEKQVDLIIHGGYLGQKPTTVI 185
Query 191 DLSGENPEVVRHGAGDVSAF 210
DL+ + P VVR G GDV F
Sbjct 186 DLTDDTPVVVREGVGDVKPF 205
>P0AFR4 Uncharacterized protein YciO [Escherichia coli (strain
K12)]
Length=206
Score = 229 bits (583), Expect = 4e-80
Identities = 108/200 (54%), Positives = 150/200 (75%), Gaps = 0/200 (0%)
Query 11 HIHPDNPQARLINQAVERIRAGDVVVYPTDAAYSIGCQIGNKSAMERIAQIRGLGPKHQY 70
+IHPDNPQ RLINQAVE +R G V+VYPTD+ Y++GC+I +K+AMERI +IR L H +
Sbjct 6 YIHPDNPQQRLINQAVEIVRKGGVIVYPTDSGYALGCKIEDKNAMERICRIRQLPDGHNF 65
Query 71 AIMCCDLSDIATYAKVDNAMYRLLKANTPSITTFILPATSEVPKRLMHPKKKTIGLRIPT 130
+MC DLS+++TY+ VDN +RL+K NTP TFIL T EVP+RL+ K+KTIG+R+P+
Sbjct 66 TLMCRDLSELSTYSFVDNVAFRLMKNNTPGNYTFILKGTKEVPRRLLQEKRKTIGMRVPS 125
Query 131 NPICQALLQELGEPILTSTLILPGQSDPLDDPYDIENQLGKRVDVFIDGGFGTLSTTSIV 190
NPI QALL+ LGEP+L+++L+LPG DP +I+++L K+VD+ I GG+ T+++
Sbjct 126 NPIAQALLEALGEPMLSTSLMLPGSEFTESDPEEIKDRLEKQVDLIIHGGYLGQKPTTVI 185
Query 191 DLSGENPEVVRHGAGDVSAF 210
DL+ + P VVR G GDV F
Sbjct 186 DLTDDTPVVVREGVGDVKPF 205
>P45103 Uncharacterized protein HI_1198 [Haemophilus influenzae
(strain ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=207
Score = 210 bits (534), Expect = 1e-72
Identities = 102/201 (51%), Positives = 144/201 (72%), Gaps = 1/201 (0%)
Query 11 HIHPDNPQARLINQAVERIRAGDVVVYPTDAAYSIGCQIGNKSAMERIAQIRGLGPKHQY 70
+IHP+NPQARLINQAVE ++ G V+VYPTD+ Y++GC +G+K AM+RI IR L H +
Sbjct 6 YIHPENPQARLINQAVEILQKGGVIVYPTDSGYALGCMMGDKHAMDRIVAIRKLPEGHNF 65
Query 71 AIMCCDLSDIATYAKVDNAMYRLLKANTPSITTFILPATSEVPKRLMHPKKKTIGLRIPT 130
++C DLS+++TYA+V+N YRL+K NTP TFIL AT E+P+RLM K+KTIGLR+P
Sbjct 66 TLVCSDLSELSTYARVNNTAYRLIKNNTPGRYTFILTATKELPRRLMTSKRKTIGLRVPD 125
Query 131 NPICQALLQELGEPILTSTLILPGQSDPL-DDPYDIENQLGKRVDVFIDGGFGTLSTTSI 189
N I LL LGEPIL+ +L+LP + DP +I ++L +VD+ I GG+ T++
Sbjct 126 NKIALDLLSALGEPILSCSLMLPNEEHTTQSDPEEIRDRLEHQVDLIIHGGYLGQEPTTV 185
Query 190 VDLSGENPEVVRHGAGDVSAF 210
VDL+ E+P ++R G+G + F
Sbjct 186 VDLTEESPVILREGSGSTAPF 206
>Q7MGL3 Threonylcarbamoyl-AMP synthase [Vibrio vulnificus (strain
YJ016)]
Length=186
Score = 73.9 bits (180), Expect = 6e-20
Identities = 41/164 (25%), Positives = 84/164 (51%), Gaps = 5/164 (3%)
Query 22 INQAVERIRAGDVVVYPTDAAYSIGCQIGNKSAMERIAQIRGLGPKHQYAIMCCDLSDIA 81
+ Q V+ ++ G VV YPT+ + +GC N+ A+ER+ I+ ++ D +
Sbjct 5 LQQVVKALKQGQVVAYPTEGVFGLGCDPDNEVAIERLLTIKQRPSDKGLILIAADFQQLQ 64
Query 82 TYAKVDNAMYRLLK---ANTPSITTFILPATSEVPKRLMHPKKKTIGLRIPTNPICQALL 138
Y + + L+ A P T+++PA++ L+ ++T+ +R+ +P+ Q L
Sbjct 65 PYLDLTSLSAEQLQRVFATWPGPYTWVMPASARA-SALVTGYRQTVAVRVSDHPLVQKLC 123
Query 139 QELGEPILTSTLILPGQSDPLDDPYDIENQLGKRVDVFIDGGFG 182
E G+P+ +++ L GQ++ +++QLG ++ V + G G
Sbjct 124 SEYGKPLTSTSANLSGQTE-CKTVEQVQDQLGSQISVILFGEIG 166
>Q8DDD6 Threonylcarbamoyl-AMP synthase [Vibrio vulnificus (strain
CMCP6)]
Length=186
Score = 73.9 bits (180), Expect = 6e-20
Identities = 41/164 (25%), Positives = 84/164 (51%), Gaps = 5/164 (3%)
Query 22 INQAVERIRAGDVVVYPTDAAYSIGCQIGNKSAMERIAQIRGLGPKHQYAIMCCDLSDIA 81
+ Q V+ ++ G VV YPT+ + +GC N+ A+ER+ I+ ++ D +
Sbjct 5 LQQVVKALKQGQVVAYPTEGVFGLGCDPDNEVAIERLLTIKQRPSDKGLILIAADFQQLQ 64
Query 82 TYAKVDNAMYRLLK---ANTPSITTFILPATSEVPKRLMHPKKKTIGLRIPTNPICQALL 138
Y + + L+ A P T+++PA++ L+ ++T+ +R+ +P+ Q L
Sbjct 65 PYLDLTSLSAEQLQRVFATWPGPYTWVMPASARA-SALVTGYRQTVAVRVSDHPLVQKLC 123
Query 139 QELGEPILTSTLILPGQSDPLDDPYDIENQLGKRVDVFIDGGFG 182
E G+P+ +++ L GQ++ +++QLG ++ V + G G
Sbjct 124 SEYGKPLTSTSANLSGQTE-CKTVEQVQDQLGSQISVILFGEIG 166
>Q3J7C4 Threonylcarbamoyl-AMP synthase [Nitrosococcus oceani (strain
ATCC 19707 / BCRC 17464 / JCM 30415 / NCIMB 11848 / C-107)]
Length=185
Score = 73.6 bits (179), Expect = 9e-20
Identities = 42/159 (26%), Positives = 76/159 (48%), Gaps = 3/159 (2%)
Query 22 INQAVERIRAGDVVVYPTDAAYSIGCQIGNKSAMERIAQIRGLGPKHQYAIMCCDLSDIA 81
+ A IR G V+ YPT+ + +GC G K+A+ERI Q++G + ++ D +
Sbjct 8 VRLAARIIRGGGVIAYPTEGVFGLGCDPGRKAAIERILQLKGRSISKGFILIAADFVQLQ 67
Query 82 TYAKVDNAMYR-LLKANTPSITTFILPATSEVPKRLMHPKKKTIGLRIPTNPICQALLQE 140
+Y A R L+ P T++LPA +VP L + T+ +R+ +P+ L +
Sbjct 68 SYLLPLTASTRSRLEVTWPGPVTWLLPARGDVPPWL-RGRYDTLAVRVTAHPLAACLCRT 126
Query 141 LGEPILTSTLILPGQSDPLDDPYDIENQLGKRVDVFIDG 179
LG +++++ G+ P + G +D + G
Sbjct 127 LGHALVSTSANRAGR-PPAQTTLQVRRSFGSSLDYILPG 164
>A1WZH9 Threonylcarbamoyl-AMP synthase [Halorhodospira halophila
(strain DSM 244 / SL1)]
Length=191
Score = 73.6 bits (179), Expect = 1e-19
Identities = 47/183 (26%), Positives = 81/183 (44%), Gaps = 13/183 (7%)
Query 22 INQAVERIRAGDVVVYPTDAAYSIGCQIGNKSAMERIAQIRGLGPKHQYAIMCCDLSDIA 81
+ A +R G VV YPT+A + +GC N A+ R+ ++G + ++ + +A
Sbjct 13 VRHAAAELRQGGVVAYPTEAVWGLGCDPRNADAVARLLALKGRPERQGLILIAAESRQLA 72
Query 82 TY-AKVDNAMYRLLKANTPSITTFILPATSEVPKRLMHPKKKTIGLRIPTNPICQALLQE 140
Y A + ++A+ P T++LPA++ P R + + T+ +R+ +P+ AL
Sbjct 73 RYLAPLPAEWAETIQASWPGPMTWVLPASTRAP-RWVSGGRDTLAVRVTAHPVAAALCSA 131
Query 141 LGEPILTSTLILPGQSDPLDDPYDIENQLGKRVDVFIDGGFGTLSTTSIVDLSGENPEVV 200
G L ST P P ++ G R+D + G G L E P +
Sbjct 132 FG-GALVSTSANPSARRPARSVAEVRRYFGTRIDALVPGRLGGL----------ERPTPI 180
Query 201 RHG 203
R G
Sbjct 181 RDG 183
>Q6LLJ9 Threonylcarbamoyl-AMP synthase [Photobacterium profundum
(strain SS9)]
Length=185
Score = 70.9 bits (172), Expect = 9e-19
Identities = 41/188 (22%), Positives = 90/188 (48%), Gaps = 15/188 (8%)
Query 22 INQAVERIRAGDVVVYPTDAAYSIGCQIGNKSAMERIAQIRGLGPKHQYAIMCCDLSDIA 81
+ Q V +++G+V+ YPT+ + +GC N A+E++ ++ + ++ + +
Sbjct 4 LQQVVSALQSGEVIAYPTEGVFGVGCDPDNPQAVEKLLALKQRPIEKGLILIAANYQQLQ 63
Query 82 TY---AKVDNAMYRLLKANTPSITTFILPATSEVPKRLMHPKKKTIGLRIPTNPICQALL 138
Y A++ + + + + P T+++P ++ L+ K +I +R+ +P+ Q L
Sbjct 64 PYIDDAQLSDLQKQKIFSTWPGPVTWVMPVKKDI-SPLLTGKFTSIAVRVSDHPLVQKLC 122
Query 139 QELGEPILTSTLILPGQSDPLDDPYDIENQLGKRVDVFIDGGFGTLSTTSIVDLSGENPE 198
+ G+PI +++ L G P +++NQLG+ + ++G G ENP
Sbjct 123 HQFGKPITSTSANLTG-LPPCKTVTEVQNQLGEHLSAILEGETG----------GRENPT 171
Query 199 VVRHGAGD 206
+R D
Sbjct 172 EIRDAFSD 179
>Q3IDH7 Threonylcarbamoyl-AMP synthase [Pseudoalteromonas translucida
(strain TAC 125)]
Length=187
Score = 70.9 bits (172), Expect = 9e-19
Identities = 44/166 (27%), Positives = 88/166 (53%), Gaps = 9/166 (5%)
Query 22 INQAVERIRAGDVVVYPTDAAYSIGCQIGNKSAMERIAQIRGLGPKHQYAIMCCDLSDIA 81
I A+ + G+V++YPT+A Y +GC N+ A+ER+ I+ + ++ + +
Sbjct 7 IAAAITCLAQGEVILYPTEAVYGLGCDPDNQQAVERLLAIKQRPVEKGLILIADNYGQLL 66
Query 82 TYAKVDNAMYRLLK-----ANTPSITTFILPATSEVPKRLMHPKKKTIGLRIPTNPICQA 136
Y VD+A + K ++ P+ T+++PA PK L + TI +R+ +P +
Sbjct 67 KY--VDDAKIPMDKRADIFSSWPNAITWVMPAAKNTPKWLT-GQYDTIAVRVTNHPTVKR 123
Query 137 LLQELGEPILTSTLILPGQSDPLDDPYDIENQLGKRVDVFIDGGFG 182
L QE G+P+++++ L GQ+ L + ++Q +++ ++D G
Sbjct 124 LCQEFGKPLVSTSANLSGQNTVLSIA-EAKSQFTEQIGYYVDEPLG 168
>P9WGC9 Putative threonylcarbamoyl-AMP synthase [Mycobacterium
tuberculosis (strain ATCC 25618 / H37Rv)]
Length=217
Score = 71.2 bits (173), Expect = 1e-18
Identities = 57/189 (30%), Positives = 91/189 (48%), Gaps = 7/189 (4%)
Query 18 QARLINQAVERIRAGDVVVYPTDAAYSIGCQIGNKSAMERIAQIRGLGPKHQYAIMCCDL 77
++R I AV I+AG +VV PTD Y IG + SA+ + +G G ++
Sbjct 13 RSRGIVSAVGAIKAGQLVVMPTDTVYGIGADAFDSSAVAALLSAKGRGRDMPVGVLVGSW 72
Query 78 SDI--ATYAKVDNAMYRLLKANTPSITTFILPATSEVPKRLMHPKKKTIGLRIPTNPICQ 135
I Y+ D A L++A P + ++ + L T+ LR+P +P+
Sbjct 73 HTIEGLVYSMPDGAR-ELIRAFWPGALSLVVVQAPSLQWDL-GDAHGTVMLRMPLHPVAI 130
Query 136 ALLQELGEPILTSTLILPGQSDPLDDPYDIENQLGKRVDVFIDGGFGTLST-TSIVDLSG 194
LL+E+G P+ S+ + G P+ D +QLG V V++D G ++IVDL+G
Sbjct 131 ELLREVG-PMAVSSANISGHPPPV-DAEQARSQLGDHVAVYLDAGPSEQQAGSTIVDLTG 188
Query 195 ENPEVVRHG 203
P V+R G
Sbjct 189 ATPRVLRPG 197
>P9WGC8 Putative threonylcarbamoyl-AMP synthase [Mycobacterium
tuberculosis (strain CDC 1551 / Oshkosh)]
Length=217
Score = 71.2 bits (173), Expect = 1e-18
Identities = 57/189 (30%), Positives = 91/189 (48%), Gaps = 7/189 (4%)
Query 18 QARLINQAVERIRAGDVVVYPTDAAYSIGCQIGNKSAMERIAQIRGLGPKHQYAIMCCDL 77
++R I AV I+AG +VV PTD Y IG + SA+ + +G G ++
Sbjct 13 RSRGIVSAVGAIKAGQLVVMPTDTVYGIGADAFDSSAVAALLSAKGRGRDMPVGVLVGSW 72
Query 78 SDI--ATYAKVDNAMYRLLKANTPSITTFILPATSEVPKRLMHPKKKTIGLRIPTNPICQ 135
I Y+ D A L++A P + ++ + L T+ LR+P +P+
Sbjct 73 HTIEGLVYSMPDGAR-ELIRAFWPGALSLVVVQAPSLQWDL-GDAHGTVMLRMPLHPVAI 130
Query 136 ALLQELGEPILTSTLILPGQSDPLDDPYDIENQLGKRVDVFIDGGFGTLST-TSIVDLSG 194
LL+E+G P+ S+ + G P+ D +QLG V V++D G ++IVDL+G
Sbjct 131 ELLREVG-PMAVSSANISGHPPPV-DAEQARSQLGDHVAVYLDAGPSEQQAGSTIVDLTG 188
Query 195 ENPEVVRHG 203
P V+R G
Sbjct 189 ATPRVLRPG 197
>Q48AU1 Threonylcarbamoyl-AMP synthase [Colwellia psychrerythraea
(strain 34H / ATCC BAA-681)]
Length=183
Score = 69.7 bits (169), Expect = 2e-18
Identities = 45/170 (26%), Positives = 84/170 (49%), Gaps = 6/170 (4%)
Query 26 VERIRAGDVVVYPTDAAYSIGCQIGNKSAMERIAQIRGLGPKHQYAIMCCDLSDIATY-- 83
VE + G ++ YPT+A + +GC NK A++R+ +++ P+ ++ S + Y
Sbjct 7 VEAFKNGGIIAYPTEAVFGLGCDPDNKEALKRLLKLKQRSPEKGLILLAGSYSQLLPYID 66
Query 84 -AKVDNAMYRLLKANTPSITTFILPATSEVPKRLMHPKKKTIGLRIPTNPICQALLQELG 142
+K+ L + P T ++P + + L+ TI +RI + P AL Q+
Sbjct 67 DSKIPQDKRLTLLSRWPDGITQLVPKNNNI-SSLLSGSFDTIAVRITSQPDVVALCQQTN 125
Query 143 EPILTSTLILPGQSDPLDDPYDIENQLGKRVDVFIDG-GFGTLSTTSIVD 191
+PI++++ L GQ +P ++ L K+VD + G G S + I+D
Sbjct 126 KPIVSTSANLSGQ-EPAKTWQSLDLVLSKQVDFILKGVTLGRTSPSKIID 174
>Q83AA2 Threonylcarbamoyl-AMP synthase [Coxiella burnetii (strain
RSA 493 / Nine Mile phase I)]
Length=186
Score = 67.0 bits (162), Expect = 2e-17
Identities = 46/177 (26%), Positives = 85/177 (48%), Gaps = 5/177 (3%)
Query 22 INQAVERIRAGDVVVYPTDAAYSIGCQIGNKSAMERIAQIRGLGPKHQYAIMCCDLSDIA 81
IN AV+ +R G V+ YPT+A Y +GC N A+ ++ I+ K + ++ + +
Sbjct 8 INDAVKCLRQGGVIAYPTEAVYGLGCDPFNHDAVAQLLTIKKRSIKKGFILIASEWKQVE 67
Query 82 TYAK-VDNAMYRLLKANTPSITTFILPATSEVPKRLMHPKKKTIGLRIPTNPICQALLQE 140
+ +D + P T+ PA+ E P + + TI +R+ +P+ + L Q
Sbjct 68 PLTEPIDPKALARVFDTWPGPFTWTFPASKEAP-HWITGQHSTIAIRVTAHPLAKLLCQR 126
Query 141 LGEPILTSTLILPGQSDPLDDPYDIENQLGKRVDVFIDGGFG-TLSTTSIVD-LSGE 195
P+++S+ G+ P+ D + G ++D ++G G T T I D ++GE
Sbjct 127 FAGPLISSSANQEGE-PPIRDVKILRLVFGNKIDKILEGPLGPTHRPTPIRDAITGE 182
>P39153 Threonylcarbamoyl-AMP synthase [Bacillus subtilis (strain
168)]
Length=346
Score = 68.2 bits (165), Expect = 5e-17
Identities = 45/184 (24%), Positives = 85/184 (46%), Gaps = 3/184 (2%)
Query 22 INQAVERIRAGDVVVYPTDAAYSIGCQIGNKSAMERIAQIRGLGPKHQYAIMCCDLSDIA 81
I QA +R +VV +PT+ Y +G N A+++I + +G + + D+S +
Sbjct 21 IAQAAALLRENEVVAFPTETVYGLGANAKNTDAVKKIYEAKGRPSDNPLIVHIADISQLE 80
Query 82 TYA-KVDNAMYRLLKANTPSITTFILPATSEVPKRLMHPKKKTIGLRIPTNPICQALLQE 140
L+K P T ILP + + +T+ +R+P +P+ AL++E
Sbjct 81 DLTGPAPEKAKTLMKRFWPGALTLILPCKPDALSPRVTAGLETVAIRMPDHPLALALIRE 140
Query 141 LGEPILTSTLILPGQSDPLDDPYDIENQLGKRVDVFIDGG-FGTLSTTSIVDLSGENPEV 199
G PI + L G+ P + + + L R+ +DGG G ++++ + + P +
Sbjct 141 SGLPIAAPSANLSGKPSPTKAEH-VAHDLDGRIAGIVDGGPTGIGVESTVLSCADDIPVL 199
Query 200 VRHG 203
+R G
Sbjct 200 LRPG 203
>Q3U5F4 Threonylcarbamoyl-AMP synthase [Mus musculus]
Length=280
Score = 62.8 bits (151), Expect = 3e-15
Identities = 42/159 (26%), Positives = 74/159 (47%), Gaps = 4/159 (3%)
Query 22 INQAVERIRAGDVVVYPTDAAYSIGCQIGNKSAMERIAQIRGLGPKHQYAIMCCDLSDIA 81
+ AV +RAG VV PTD Y + C + +A+ + +++G A+ ++D+
Sbjct 71 LRAAVAELRAGAVVAVPTDTLYGLACSASSSAALSCVYRLKGRSEAKPLAVCLGRVADVY 130
Query 82 TYAKVDNAMYRLLKANTPSITTFILPATSEVPKRLMHPKKKTIGLRIPTNPICQALLQEL 141
Y +V LL+ P T ++ + E+ K L +P + +G+RIP + L Q
Sbjct 131 RYCQV-RVPRELLEDLFPGPVTLVMERSEELNKDL-NPFTRLVGIRIPDHAFMLDLAQMF 188
Query 142 GEPILTSTLILPGQSDPLDDPYDIENQLGKRVDVFIDGG 180
G P+ ++ L Q+ L + L + + IDGG
Sbjct 189 GGPLALTSANLSSQASSLS--VEEFQDLWPHLSLVIDGG 225
>Q86U90 Threonylcarbamoyl-AMP synthase [Homo sapiens]
Length=279
Score = 62.4 bits (150), Expect = 4e-15
Identities = 43/159 (27%), Positives = 74/159 (47%), Gaps = 4/159 (3%)
Query 22 INQAVERIRAGDVVVYPTDAAYSIGCQIGNKSAMERIAQIRGLGPKHQYAIMCCDLSDIA 81
+ AV +RAG VV PTD Y + C +A+ + +++G A+ ++D+
Sbjct 70 LRAAVAELRAGAVVAVPTDTLYGLACAASCSAALRAVYRLKGRSEAKPLAVCLGRVADVY 129
Query 82 TYAKVDNAMYRLLKANTPSITTFILPATSEVPKRLMHPKKKTIGLRIPTNPICQALLQEL 141
Y +V LLK P T ++ + E+ K L +P +G+RIP + Q L Q
Sbjct 130 RYCRV-RVPEGLLKDLLPGPVTLVMERSEELNKDL-NPFTPLVGIRIPDHAFMQDLAQMF 187
Query 142 GEPILTSTLILPGQSDPLDDPYDIENQLGKRVDVFIDGG 180
P+ ++ L Q+ L+ + L ++ + IDGG
Sbjct 188 EGPLALTSANLSSQASSLN--VEEFQDLWPQLSLVIDGG 224
>P45748 Threonylcarbamoyl-AMP synthase [Escherichia coli (strain
K12)]
Length=190
Score = 57.8 bits (138), Expect = 6e-14
Identities = 44/187 (24%), Positives = 89/187 (48%), Gaps = 10/187 (5%)
Query 15 DNPQARLINQAVERIRAGDVVVYPTDAAYSIGCQIGNKSAMERIAQIRGLGPKHQYAIMC 74
+N Q I A++ + V+ YPT+A + +GC +++A+ R+ +++ ++
Sbjct 3 NNLQRDAIAAAIDVLNEERVIAYPTEAVFGVGCDPDSETAVMRLLELKQRPVDKGLILIA 62
Query 75 CDLSDIATYAKVDNAMYRLLKANT-----PSITTFILPATSEVPKRLMHPKKKTIGLRIP 129
+ + Y +D+ M ++ T P TF+ PA + P R + + ++ +R+
Sbjct 63 ANYEQLKPY--IDDTMLTDVQRETIFSRWPGPVTFVFPAPATTP-RWLTGRFDSLAVRVT 119
Query 130 TNPICQALLQELGEPILTSTLILPGQSDPLDDPYDIENQLGKRVDVFIDGGFGTLSTTSI 189
+P+ AL Q G+P+++++ L G P ++ Q G V G L+ + I
Sbjct 120 DHPLVVALCQAYGKPLVSTSANLSG-LPPCRTVDEVRAQFGAAFPVVPGETGGRLNPSEI 178
Query 190 VD-LSGE 195
D L+GE
Sbjct 179 RDALTGE 185
>P32579 Threonylcarbamoyl-AMP synthase [Saccharomyces cerevisiae
(strain ATCC 204508 / S288c)]
Length=426
Score = 38.1 bits (87), Expect = 8e-07
Identities = 37/188 (20%), Positives = 74/188 (39%), Gaps = 18/188 (10%)
Query 33 DVVVYPTDAAYSIGCQIGNKSAM-------------ERIAQIRGLGPKHQYAIMCCDLSD 79
+ V +PT+ Y +G N +++ I + + ++ LS
Sbjct 64 ETVAFPTETVYGLGGSALNDNSVLSIYRAKNRPSDNPLITHVSSIDQLNRKVFNQPHLSG 123
Query 80 IATYAKVDNAMYRLLKANTPSITTFILPATSE---VPKRLMHPKKKTIGLRIPTNPICQA 136
+ + + + L+ + P T +LP S +L + T +RIP NP+ +A
Sbjct 124 TSLFDNIPSIYRPLISSLWPGPLTILLPVPSSEHSALSKLTTADQPTFAVRIPANPVARA 183
Query 137 LLQELGEPILTSTLILPGQSDPLDDPYDIENQLGKRVDVFIDGGFGTLSTTS-IVDLSGE 195
L+ PI + + P + + + L ++ + +DGG + S +VD
Sbjct 184 LIALSDTPIAAPSANASTRPSPTLASH-VYHDLKDKIPIILDGGACKVGVESTVVDGLCN 242
Query 196 NPEVVRHG 203
P ++R G
Sbjct 243 PPTLLRPG 250
Score = 21.2 bits (43), Expect = 0.25
Identities = 7/24 (29%), Positives = 16/24 (67%), Gaps = 0/24 (0%)
Query 47 CQIGNKSAMERIAQIRGLGPKHQY 70
C++ NK +E+ ++R G K+++
Sbjct 268 CKVENKKTVEKGEKVRTPGMKYRH 291
Lambda K H a alpha
0.321 0.139 0.415 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 596790
Database: 1fbe0f24fc9ed02b9a4944d7c46fe3ee.SwissProt.fasta
Posted date: Jun 4, 2024 5:54 PM
Number of letters in database: 4,269
Number of sequences in database: 19
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
