BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: a21e305bf7a095e41a6961f028396b10.SwissProt.fasta
15 sequences; 15,138 total letters
Query= ACIAD1407
Length=171
Score E
Sequences producing significant alignments: (Bits) Value
P34549 Uncharacterized protein R10E11.5 [Caenorhabditis elegans] 40.0 4e-07
Q6BWW6 E3 ubiquitin-protein ligase BRE1 [Debaryomyces hansenii (s... 38.5 1e-06
O30189 Uncharacterized protein AF_0047 [Archaeoglobus fulgidus (s... 37.0 2e-06
A6RIE1 Protein pxr1 [Botryotinia fuckeliana (strain B05.10)] 37.7 2e-06
Q39WF6 Ribonuclease Y [Geobacter metallireducens (strain ATCC 537... 37.0 4e-06
P71378 Uncharacterized protein HI_1339/HI_1462.1 [Haemophilus inf... 35.4 6e-06
A0PX77 tRNA modification GTPase MnmE [Clostridium novyi (strain NT)] 35.8 1e-05
Q8BL66 Early endosome antigen 1 [Mus musculus] 35.8 1e-05
P40847 Switch-activating protein 1 [Schizosaccharomyces pombe (st... 35.0 1e-05
F6ZDS4 Nucleoprotein TPR [Mus musculus] 35.4 2e-05
Q8L7E5 WPP domain-interacting tail-anchored protein 1 [Arabidopsi... 35.0 2e-05
O94986 Centrosomal protein of 152 kDa [Homo sapiens] 34.7 3e-05
Q8IWJ2 GRIP and coiled-coil domain-containing protein 2 [Homo sap... 34.3 4e-05
P12270 Nucleoprotein TPR [Homo sapiens] 28.5 0.003
Q8JHV6 Laminin subunit beta-4 [Danio rerio] 25.0 0.042
>P34549 Uncharacterized protein R10E11.5 [Caenorhabditis elegans]
Length=444
Score = 40.0 bits (92), Expect = 4e-07
Identities = 31/120 (26%), Positives = 56/120 (47%), Gaps = 13/120 (11%)
Query 62 GAFSRAEEEGNKLFDSLVK--------VGEELESKTIDAADQTVTKVTEKAKESVTDTKD 113
GA +AEEE + D VK V +++E + D +TK EK+ +S+ +T D
Sbjct 304 GALQKAEEEVVQTIDQTVKNIKSNVNEVKKDVEKNIAEKVDD-ITKELEKSAKSLEETTD 362
Query 114 KVEKMIDHSVHHSLNRIGLVTIKDIQNIEQLLIQLNAKVDSLVQENEK----LQQKLDEK 169
K+ ID++ + + ++K +++ + + L E +K +QKLD K
Sbjct 363 KIGSKIDNTSQAIKSNLEEASLKTEKSVNDAVKSGEKLIGDLASEAKKTFDSAEQKLDAK 422
Score = 25.4 bits (54), Expect = 0.028
Identities = 37/192 (19%), Positives = 78/192 (41%), Gaps = 33/192 (17%)
Query 9 LESKQEFKQMEKKLTNSKNTEHDLEKNDEKSKC------SRKSGLDFRKYTKQIWLAG-- 60
++ ++EF KK + L KND K+ + ++ + K+ +AG
Sbjct 155 VQDREEFMNEMKKHKIELEKKKSLGKNDSKTTIEIPTPKAAETQQEHVKFAHAPEIAGNS 214
Query 61 ---LGAFSRAEEE---------GNKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESV 108
+ S +EE NK+ D ++V + + T ++ + +K V
Sbjct 215 QKAVRIQSETQEEAPVAVKNLSANKMNDQ-IEVSQLMNEITPESVPAVESLDNQKNANVV 273
Query 109 TDTKDKVEKMIDHSVHHSLNRIGLVTIK-----------DIQNIEQLLIQLNAKVDSLVQ 157
D KV+K+ D ++ S + K +Q I+Q + + + V+ + +
Sbjct 274 GDLLAKVQKVADDTIDKSKTTVAADVAKMSGALQKAEEEVVQTIDQTVKNIKSNVNEVKK 333
Query 158 ENEK-LQQKLDE 168
+ EK + +K+D+
Sbjct 334 DVEKNIAEKVDD 345
Score = 24.3 bits (51), Expect = 0.066
Identities = 32/132 (24%), Positives = 51/132 (39%), Gaps = 20/132 (15%)
Query 10 ESKQEFKQMEKKLTNSKN-TEHDLEKN-----DEKSKCSRKSGLDFRKYTKQIWL----- 58
E Q Q K + ++ N + D+EKN D+ +K KS + T +I
Sbjct 312 EVVQTIDQTVKNIKSNVNEVKKDVEKNIAEKVDDITKELEKSAKSLEETTDKIGSKIDNT 371
Query 59 --AGLGAFSRAEEEGNKLFDSLVKVGEEL-------ESKTIDAADQTVTKVTEKAKESVT 109
A A + K + VK GE+L KT D+A+Q + K +
Sbjct 372 SQAIKSNLEEASLKTEKSVNDAVKSGEKLIGDLASEAKKTFDSAEQKLDAKFSKIGSTAD 431
Query 110 DTKDKVEKMIDH 121
T + V+ + H
Sbjct 432 STLEDVKNGLRH 443
>Q6BWW6 E3 ubiquitin-protein ligase BRE1 [Debaryomyces hansenii
(strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC
0083 / IGC 2968)]
Length=691
Score = 38.5 bits (88), Expect = 1e-06
Identities = 28/99 (28%), Positives = 50/99 (51%), Gaps = 8/99 (8%)
Query 77 SLVKVGEELESKTIDAADQTVTK---VTEKAKESV-----TDTKDKVEKMIDHSVHHSLN 128
+LVK + SKT+ D+++T V E+A E+V DT K E +D+ ++
Sbjct 192 TLVKDNDRRSSKTLQRIDESLTNGSDVKEEASETVKSEVNKDTTVKNENSVDNEEFERIS 251
Query 129 RIGLVTIKDIQNIEQLLIQLNAKVDSLVQENEKLQQKLD 167
D + +++ + Q+N D +V+EN +L KL+
Sbjct 252 SEIEELKSDNRLLKESMNQINTNYDKVVKENLQLSDKLE 290
Score = 27.3 bits (59), Expect = 0.007
Identities = 34/164 (21%), Positives = 65/164 (40%), Gaps = 15/164 (9%)
Query 10 ESKQEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGLGAFSRAEE 69
ESK E Q + LT K+ + K ++ S +G D ++ + + + + +
Sbjct 180 ESKVEDLQAQL-LTLVKDNDRRSSKTLQRIDESLTNGSDVKEEASETVKSEVNKDTTVKN 238
Query 70 EGNKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMIDHSVHHS--- 126
E + + ++ E+E D KES+ +K++ ++ S
Sbjct 239 ENSVDNEEFERISSEIEELKSD---------NRLLKESMNQINTNYDKVVKENLQLSDKL 289
Query 127 --LNRIGLVTIKDIQNIEQLLIQLNAKVDSLVQENEKLQQKLDE 168
LN L+ Q + QLN V++L + N+ KL+E
Sbjct 290 ENLNENDLINSVSYQELAAHNKQLNESVNNLQKINDTTVNKLNE 333
Score = 26.2 bits (56), Expect = 0.017
Identities = 26/101 (26%), Positives = 45/101 (45%), Gaps = 7/101 (7%)
Query 72 NKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMIDHS--VHHSLNR 129
NK+ + + +EL SK D + K+ E +S D K + + + + SL
Sbjct 499 NKILKTQINKSQELVSKLNDLEKSYLDKI-EILTKSNNDFKIIRQSALQENSKLQESLRA 557
Query 130 IGLVTIKDIQNIEQLLIQLNAKVDSLVQENEKLQQKLDEKS 170
I + ++E+ L + K VQEN Q+L+EK+
Sbjct 558 IDVRKA----SLEKELSGMKDKYSDKVQENTSFTQELNEKN 594
Score = 22.7 bits (47), Expect = 0.22
Identities = 19/85 (22%), Positives = 38/85 (45%), Gaps = 2/85 (2%)
Query 86 ESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMIDHSVHHSLNRIGLVTIKDIQNIEQLL 145
E K I+ A Q + + SVTD ++ V+K+ + +KD + E +
Sbjct 442 EIKEIEQAFQETRENSLSKLMSVTDQENMVKKLTIEKTKADQKYFASMRLKDSLSSENKI 501
Query 146 I--QLNAKVDSLVQENEKLQQKLDE 168
+ Q+N + + + N+ + LD+
Sbjct 502 LKTQINKSQELVSKLNDLEKSYLDK 526
Score = 18.5 bits (36), Expect = 5.1
Identities = 9/28 (32%), Positives = 16/28 (57%), Gaps = 0/28 (0%)
Query 137 DIQNIEQLLIQLNAKVDSLVQENEKLQQ 164
D ++ + + LNA+V +L EN L +
Sbjct 147 DKSDVLEKIEVLNAEVATLKSENNTLSK 174
>O30189 Uncharacterized protein AF_0047 [Archaeoglobus fulgidus
(strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)]
Length=144
Score = 37.0 bits (84), Expect = 2e-06
Identities = 27/124 (22%), Positives = 61/124 (49%), Gaps = 20/124 (16%)
Query 47 LDFRKYTKQIWLAGLGAFSRAEEEGNKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKE 106
L++RK + +A L + +EE K + +K G E E + A T+ + ++A
Sbjct 9 LEYRKEQLENKVAWLEKRVKEKEEFKKTIHAEIKSGVEPELNKLKAKADTIFEEAKRA-- 66
Query 107 SVTDTKDKVEKMIDHSVHHSLNRIGLVTIKDIQNIEQLLIQLNAKVDSLVQENEKLQQKL 166
T+ +DK+ + IK+I + L++ + K++ ++E +K+++KL
Sbjct 67 --TELRDKI----------------VAEIKEIVEVLSKLLEASEKLEGEIEEEKKVKEKL 108
Query 167 DEKS 170
++++
Sbjct 109 EKET 112
Score = 21.9 bits (45), Expect = 0.28
Identities = 28/118 (24%), Positives = 51/118 (43%), Gaps = 29/118 (25%)
Query 4 NPIKWLES----KQEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLA 59
N + WLE K+EFK+ + + E E +K K+ F +
Sbjct 18 NKVAWLEKRVKEKEEFKK-------TIHAEIKSGVEPELNKLKAKADTIFEE-------- 62
Query 60 GLGAFSRAEEEGNKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVEK 117
RA E +K+ + ++ E L SK ++A+++ ++ E+ K K+K+EK
Sbjct 63 ----AKRATELRDKIVAEIKEIVEVL-SKLLEASEKLEGEIEEEKK-----VKEKLEK 110
>A6RIE1 Protein pxr1 [Botryotinia fuckeliana (strain B05.10)]
Length=368
Score = 37.7 bits (86), Expect = 2e-06
Identities = 30/109 (28%), Positives = 53/109 (49%), Gaps = 14/109 (13%)
Query 10 ESKQEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGLGAFSRAEE 69
+SK+E K+ ++K + + +E + EK+ +SK S+KS D + +K S +E
Sbjct 211 KSKKEKKEKKEKKSKKRQSEDEDEKDKSESKKSKKSKKDRKSKSK----------STSEA 260
Query 70 EGNKLFDSLVKV----GEELESKTIDAADQTVTKVTEKAKESVTDTKDK 114
E L +S +K +E + K +AA + + +K S KDK
Sbjct 261 EDETLDESALKARKKEKKEKKRKEKEAAGADTEEASSTSKSSKKSKKDK 309
Score = 28.1 bits (61), Expect = 0.003
Identities = 22/95 (23%), Positives = 44/95 (46%), Gaps = 10/95 (11%)
Query 12 KQEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGLGAFSRAEEEG 71
K+E ++ E+K ++ K+ + EK ++KSK + D + ++ S+ ++
Sbjct 197 KREEQEDEEKTSSKKSKKEKKEKKEKKSKKRQSEDEDEKDKSE----------SKKSKKS 246
Query 72 NKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKE 106
K S K E E +T+D + K +K K+
Sbjct 247 KKDRKSKSKSTSEAEDETLDESALKARKKEKKEKK 281
Score = 23.5 bits (49), Expect = 0.11
Identities = 26/112 (23%), Positives = 48/112 (43%), Gaps = 10/112 (9%)
Query 10 ESKQEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGLGAFSRAEE 69
E K EKK ++ + E E+ DE+ S+KS + ++ ++ S E+
Sbjct 180 EEKSPEPVAEKKKSSKRKRE---EQEDEEKTSSKKSKKEKKEKKEK---KSKKRQSEDED 233
Query 70 EGNKLFDSLVKVGEE----LESKTIDAADQTVTKVTEKAKESVTDTKDKVEK 117
E +K K ++ T +A D+T+ + KA++ K + EK
Sbjct 234 EKDKSESKKSKKSKKDRKSKSKSTSEAEDETLDESALKARKKEKKEKKRKEK 285
Score = 21.9 bits (45), Expect = 0.36
Identities = 16/45 (36%), Positives = 21/45 (47%), Gaps = 3/45 (7%)
Query 10 ESKQEFKQMEKKLTNSKNTEH---DLEKNDEKSKCSRKSGLDFRK 51
ES + ++ EKK K E D E+ SK S+KS D K
Sbjct 267 ESALKARKKEKKEKKRKEKEAAGADTEEASSTSKSSKKSKKDKHK 311
Score = 18.5 bits (36), Expect = 4.8
Identities = 9/43 (21%), Positives = 21/43 (49%), Gaps = 0/43 (0%)
Query 70 EGNKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTK 112
+G K +++ E+ + + +D + + EK+ E V + K
Sbjct 149 DGEKERLKALEIKEKAAESSSEESDSSSDEEEEKSPEPVAEKK 191
>Q39WF6 Ribonuclease Y [Geobacter metallireducens (strain ATCC
53774 / DSM 7210 / GS-15)]
Length=520
Score = 37.0 bits (84), Expect = 4e-06
Identities = 42/137 (31%), Positives = 64/137 (47%), Gaps = 37/137 (27%)
Query 59 AGLGAFSRAEEEGN----KLFDSLVKVGEELESKTIDAAD---QTVTKVTE-KAKESV-- 108
AGLG F GN ++ D+LV EEL SK +D A +T+TK E KAK+ V
Sbjct 14 AGLGYFV-----GNMLRKRISDTLVSKAEELASKIVDDAKREAETITKEAELKAKDEVFQ 68
Query 109 ------TDTKDK------VEKMIDHSVHHSLNRIGLVTIKD---------IQNIEQLLIQ 147
D K+K +EK + + ++ L +D + N EQ L+Q
Sbjct 69 AKAEAERDAKEKRKDLQALEKRLQQKEENLDKKMNLFDQRDADLTKKDQALLNREQGLVQ 128
Query 148 LNAKVDSLV-QENEKLQ 163
++D L+ ++ EKL+
Sbjct 129 KEERLDGLIAEQREKLE 145
Score = 23.9 bits (50), Expect = 0.090
Identities = 33/113 (29%), Positives = 51/113 (45%), Gaps = 15/113 (13%)
Query 7 KWLESKQEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGLGAFSR 66
K L+ K+E ++KK+ + DL K D+ + +R+ GL K+ L GL A R
Sbjct 89 KRLQQKEE--NLDKKMNLFDQRDADLTKKDQ-ALLNREQGL----VQKEERLDGLIAEQR 141
Query 67 AEEEGNKLFDS-----LVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDK 114
+ E S ++ E E+K +DAA + KV E+ D K K
Sbjct 142 EKLESISGLSSTEAKKILMDAMESEAK-LDAAKR--IKVIEEEARETADKKSK 191
>P71378 Uncharacterized protein HI_1339/HI_1462.1 [Haemophilus
influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=129
Score = 35.4 bits (80), Expect = 6e-06
Identities = 22/59 (37%), Positives = 36/59 (61%), Gaps = 2/59 (3%)
Query 62 GAFSRAEEEGNKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMID 120
G F + E + K+ D+ V + S+T DAA T+T+V EKA++ TD K+KV + ++
Sbjct 22 GCFDKQEAK-QKVEDTKQTVAS-VASETKDAAANTMTEVKEKAQQLSTDVKNKVAEKVE 78
Score = 21.2 bits (43), Expect = 0.47
Identities = 15/67 (22%), Positives = 31/67 (46%), Gaps = 4/67 (6%)
Query 102 EKAKESVTDTKDKVEKMIDHSVHHSLNRIGLVTIKDIQNIEQLLIQLNAKVDSLVQENEK 161
++AK+ V DTK V + + + N + V + +QL + KV V++ ++
Sbjct 27 QEAKQKVEDTKQTVASVASETKDAAANTMTEVK----EKAQQLSTDVKNKVAEKVEDAKE 82
Query 162 LQQKLDE 168
+ + E
Sbjct 83 VIKSATE 89
>A0PX77 tRNA modification GTPase MnmE [Clostridium novyi (strain
NT)]
Length=459
Score = 35.8 bits (81), Expect = 1e-05
Identities = 20/71 (28%), Positives = 42/71 (59%), Gaps = 2/71 (3%)
Query 66 RAEEEGNKLFDSLVKVGEELESKTIDAADQTVTKVT-EKAKESVTDTKDKVEKMIDHSVH 124
+ E K+ + L+++ +E+ T+D + + +VT EK +ESV+ D+++ ++DH+
Sbjct 158 KLSREIGKIRNKLLEIIASIEA-TVDYPEDDLEEVTSEKGRESVSKLLDEIDSLLDHADE 216
Query 125 HSLNRIGLVTI 135
+ R GL T+
Sbjct 217 GKILREGLNTV 227
>Q8BL66 Early endosome antigen 1 [Mus musculus]
Length=1411
Score = 35.8 bits (81), Expect = 1e-05
Identities = 39/177 (22%), Positives = 85/177 (48%), Gaps = 20/177 (11%)
Query 9 LESKQEFKQMEKKLT-NSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGLGAFSRA 67
L+S Q+ +Q+ L + +L++ +E C++ LD + + +I ++
Sbjct 750 LQSLQQQRQLSTDLELRNAELSRELQEQEEVVSCTK---LDLQNKS-EILENIKQTLTKK 805
Query 68 EEEGNKLFDSLVKVGEELESKTIDAADQTVTKVTE----KAKE-----SVTDTKDKVEKM 118
EEE L K+ ++ +++ + D+ VTE KA++ ++ TK+K+ K+
Sbjct 806 EEENVVLKQEFEKLSQDSKTQHKELGDRMQAAVTELTAVKAQKDALLAELSTTKEKLSKV 865
Query 119 ID-----HSVHHSLNRIGLVTIKDIQN-IEQLLIQLNAKVDSLVQENEKLQQKLDEK 169
D S N+ G + D++ ++L QL + +S ++E E L++ L+++
Sbjct 866 SDSLKNSKSEFEKENQKGKAAVLDLEKACKELKHQLQVQAESALKEQEDLKKSLEKE 922
Score = 33.9 bits (76), Expect = 5e-05
Identities = 45/200 (23%), Positives = 82/200 (41%), Gaps = 50/200 (25%)
Query 16 KQMEKKLTNSKNTEHDLEKNDEKSKCS-----------RKSGLDFRKYTKQI-------- 56
+Q+++K+TNS +H LEK+ ++ + R++ D + +QI
Sbjct 467 EQLKEKVTNSTELQHQLEKSKQQHQEQQALQQSATAKLREAQNDLEQVLRQIGDKDQKIQ 526
Query 57 -----WLAGLGAFSRAEEEGNKLFDSLVKVGE-------ELESKTIDAADQTVTKVTEKA 104
G + S E+E L+ + ++ GE +L+ K A Q +T++TEK
Sbjct 527 NLEALLQKGKESVSLLEKEREDLY-AKIQAGEGETAVLNQLQEKN-HALQQQLTQLTEKL 584
Query 105 KESVTDTKDKVEKMIDH----------------SVHHSLNRIGLVTIKDIQNIEQLLIQL 148
K K E + D S+ S++ + + + + QL IQ+
Sbjct 585 KNQSESHKQAEENLHDQVQEQKAHLRAAQDRVLSLETSVSELSSQLNESKEKVSQLDIQI 644
Query 149 NAKVDSLVQ-ENEKLQQKLD 167
AK + L+ E K Q+ D
Sbjct 645 KAKTELLLSAEAAKAAQRAD 664
Score = 33.5 bits (75), Expect = 7e-05
Identities = 39/167 (23%), Positives = 74/167 (44%), Gaps = 27/167 (16%)
Query 7 KWLESKQEFKQMEKK----LTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGLG 62
K LE Q +Q E K +T+S LE+ E+++ + + +Q
Sbjct 111 KELEKYQGLQQQEAKSDGLVTDSSAELQALEQQLEEAQTENFNIKQMKDLFEQ------- 163
Query 63 AFSRAEEEGNKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMIDHS 122
+A + ++ D K EE + AA+Q VT +TE + T +D ++
Sbjct 164 ---KAAQLATEIADIKSKYDEEKSLRA--AAEQKVTHLTEDLNKQTTVIQDLKTEL---- 214
Query 123 VHHSLNRIGLVTIKDIQNIEQLLIQLNAKVDSLVQENEKLQQKLDEK 169
L R G I+D+ +++ L+Q+ +D++ E E+ +KL ++
Sbjct 215 ----LQRPG---IEDVAVLKKELVQVQTLMDNMTLERERESEKLKDE 254
Score = 26.2 bits (56), Expect = 0.017
Identities = 19/73 (26%), Positives = 37/73 (51%), Gaps = 6/73 (8%)
Query 102 EKAKESVTDTKDKVEKMIDHSVH--HSLNRIGLVTIKDIQNIE---QLLIQLNAKVDSLV 156
E+ +ES KD+ +K+ H ++N++ K Q + Q + +L ++ L
Sbjct 243 ERERES-EKLKDECKKLQSEHAHLEATINQLRSELAKGPQEVAVYVQEIQKLKGSINELT 301
Query 157 QENEKLQQKLDEK 169
Q+N+ L +KL +K
Sbjct 302 QKNQNLTEKLQKK 314
Score = 25.0 bits (53), Expect = 0.041
Identities = 42/161 (26%), Positives = 63/161 (39%), Gaps = 30/161 (19%)
Query 12 KQEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGLGAFSRAEEEG 71
KQEF+ KL+ T+H E D + L K K LA L S +E+
Sbjct 813 KQEFE----KLSQDSKTQHK-ELGDRMQAAVTE--LTAVKAQKDALLAEL---STTKEKL 862
Query 72 NKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMIDHSVHHSLNR-- 129
+K+ DSL E E K +K K +V D +K K + H +
Sbjct 863 SKVSDSLKNSKSEFE------------KENQKGKAAVLDL-EKACKELKHQLQVQAESAL 909
Query 130 -----IGLVTIKDIQNIEQLLIQLNAKVDSLVQENEKLQQK 165
+ K+ + +QL I+LN+ + Q L+QK
Sbjct 910 KEQEDLKKSLEKEKETSQQLKIELNSVKGEVSQAQNTLKQK 950
Score = 24.6 bits (52), Expect = 0.055
Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 15/104 (14%)
Query 65 SRAEEEGNKLFDSLVKVGEELESKTIDAADQTVTK--VTEKAKESVTDTKDKVEKMIDHS 122
SR EE+ + + ++ +LE +Q + T K +E+ D + + ++ D
Sbjct 463 SRLEEQLKEKVTNSTELQHQLEKSKQQHQEQQALQQSATAKLREAQNDLEQVLRQIGDKD 522
Query 123 VHHSLNRIGLVTIKDIQNIEQLLIQLNAKVDSLVQENEKLQQKL 166
+ IQN+E LL + V L +E E L K+
Sbjct 523 -------------QKIQNLEALLQKGKESVSLLEKEREDLYAKI 553
Score = 23.5 bits (49), Expect = 0.13
Identities = 35/166 (21%), Positives = 75/166 (45%), Gaps = 17/166 (10%)
Query 10 ESKQEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWL---AGLGAFSR 66
+ K++ +E+K+ + + LE + + K S++ L + +Q+ SR
Sbjct 713 DHKEKHLSLEQKVEDLEGHIKKLEADALEVKASKEQALQSLQQQRQLSTDLELRNAELSR 772
Query 67 AEEEGNKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMIDHSV--H 124
+E ++ S K+ + +S+ ++ QT+TK K +E+V K + EK+ S H
Sbjct 773 ELQEQEEVV-SCTKLDLQNKSEILENIKQTLTK---KEEENVV-LKQEFEKLSQDSKTQH 827
Query 125 HSLNRIGLVTIKDIQNIEQLLIQLNAKVDSLVQENEKLQQKLDEKS 170
L + ++ ++ A+ D+L+ E ++KL + S
Sbjct 828 KELGDRMQAAVTELTAVK-------AQKDALLAELSTTKEKLSKVS 866
Score = 23.1 bits (48), Expect = 0.17
Identities = 40/184 (22%), Positives = 79/184 (43%), Gaps = 25/184 (14%)
Query 12 KQEFKQMEKKLTNSKNTEHDLEKNDEKSKCS----RKSGLDFRKYTKQIWLAGLGAFSRA 67
K E ++ +++ ++NT EK++++ + + ++S +K + + A S+
Sbjct 930 KIELNSVKGEVSQAQNTLKQKEKDEQQLQGTINQLKQSAEQKKKQIEALQGEVKNAVSQK 989
Query 68 EEEGNKLFDSLVKVGEEL--ESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMID----- 120
NKL + +EL E + A K K+ +D K +++
Sbjct 990 TVLENKLQQQSSQAAQELAAEKGKLSALQSNYEKCQADLKQLQSDLYGKESELLATRQDL 1049
Query 121 HSVHHSL-----------NRIG--LVTIKDIQNIEQLLIQLNAKVDSLVQENEK-LQQKL 166
SV L N+IG +I+++Q + L Q +AK ++L++E K L+
Sbjct 1050 KSVEEKLTLAQEDLISNRNQIGNQNKSIQELQAAKASLEQDSAKKEALLKEQSKALEDAQ 1109
Query 167 DEKS 170
EKS
Sbjct 1110 REKS 1113
Score = 22.7 bits (47), Expect = 0.23
Identities = 32/167 (19%), Positives = 73/167 (44%), Gaps = 23/167 (14%)
Query 12 KQEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGLGAFSRAEEEG 71
+Q+ Q+ +KL N + E+N +K+ L R ++ L + E
Sbjct 574 QQQLTQLTEKLKNQSESHKQAEENLHDQVQEQKAHL--RAAQDRV----LSLETSVSELS 627
Query 72 NKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMIDHSVH------H 125
++L +S KV + +D + T++ A+ + + ++ +D + H
Sbjct 628 SQLNESKEKVSQ------LDIQIKAKTELLLSAEAAKAAQRADLQNHLDTAQHALQDKQQ 681
Query 126 SLNRIGL----VTIKDIQNIEQLLIQLNAKVDSLVQENEKLQQKLDE 168
LN++ + +T K Q ++ IQL + + +++ L+QK+++
Sbjct 682 ELNKVSVQLDQLTAK-FQEKQEHCIQLESHLKDHKEKHLSLEQKVED 727
Score = 18.5 bits (36), Expect = 5.2
Identities = 19/84 (23%), Positives = 37/84 (44%), Gaps = 9/84 (11%)
Query 10 ESKQEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKS--------GLDFRKYTKQIWLAGL 61
E Q+ + + +KL LE+ + SRK+ LD ++ ++ A
Sbjct 299 ELTQKNQNLTEKLQKKDLDYTHLEEKHNEESASRKTLQASLHQRDLDCQQLQARL-TASE 357
Query 62 GAFSRAEEEGNKLFDSLVKVGEEL 85
+ RA+ E ++ ++ K+ EEL
Sbjct 358 SSLQRAQGELSEKAEAAQKLREEL 381
Score = 18.1 bits (35), Expect = 6.9
Identities = 9/31 (29%), Positives = 18/31 (58%), Gaps = 0/31 (0%)
Query 139 QNIEQLLIQLNAKVDSLVQENEKLQQKLDEK 169
Q + + L ++ + L E ++LQQ+ +EK
Sbjct 375 QKLREELREVESTRQHLKVEVKQLQQQREEK 405
>P40847 Switch-activating protein 1 [Schizosaccharomyces pombe
(strain 972 / ATCC 24843)]
Length=254
Score = 35.0 bits (79), Expect = 1e-05
Identities = 15/32 (47%), Positives = 25/32 (78%), Gaps = 0/32 (0%)
Query 136 KDIQNIEQLLIQLNAKVDSLVQENEKLQQKLD 167
K + + E+ L+Q+NAK+D ++ EN++LQQ LD
Sbjct 172 KHLHDNEEKLMQVNAKMDEVLAENKRLQQLLD 203
>F6ZDS4 Nucleoprotein TPR [Mus musculus]
Length=2431
Score = 35.4 bits (80), Expect = 2e-05
Identities = 34/124 (27%), Positives = 64/124 (52%), Gaps = 16/124 (13%)
Query 9 LESKQEFKQMEKKLTNSK-----------NTEHDLEKNDEKSKCSRKSGLDFRKYTKQIW 57
+ES+Q++ ++EK+L+ S+ N +LEK + + K + + T Q
Sbjct 122 VESEQQYFEIEKRLSQSQERLVTETRECQNLRLELEKLNNQVKVLTEKTKELE--TAQDR 179
Query 58 LAGLGA-FSRAEEEGNKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVE 116
G+ + F+RA+EE L++ E L S+ ++ + V ++ EK KES T TK +++
Sbjct 180 NLGIQSQFTRAKEELEAEKRDLIRTNERL-SQEVEYLTEDVKRLNEKLKESNT-TKGELQ 237
Query 117 KMID 120
+D
Sbjct 238 LKLD 241
Score = 30.0 bits (66), Expect = 0.001
Identities = 38/177 (21%), Positives = 72/177 (41%), Gaps = 21/177 (12%)
Query 12 KQEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLD----FRKYTKQIWLAGLGAFSRA 67
+ E ++KKL N H L +N + K LD TK++ +
Sbjct 919 EHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTEINLHLNTKELLKNAQKDIATL 978
Query 68 EEEGNKLFDSLVKVGEELESK----TIDAADQTVTKVTEKAKESVTDTKDKVEKMIDH-- 121
++ N + L + K D D +++ +A+E V D K++++ +
Sbjct 979 KQHLNNMEAQLASQSTQRTGKGQPGDRDDVDDLKSQL-RQAEEQVNDLKERLKTSTSNVE 1037
Query 122 -------SVHHSLNRIGLVTIKDIQNIEQLL---IQLNAKVDSLVQENEKLQQKLDE 168
S+ SLN+ VT + +NIE L + +++ + E EK +Q+L +
Sbjct 1038 QYRAMVTSLEDSLNKEKQVTEEVHKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQD 1094
Score = 28.5 bits (62), Expect = 0.003
Identities = 31/149 (21%), Positives = 64/149 (43%), Gaps = 7/149 (5%)
Query 12 KQEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGLGAFSRAEEEG 71
K+E ++E+++ K + L+K+ E K + + ++ + L A +
Sbjct 304 KEEVLRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKL---- 359
Query 72 NKLFDSLVKVGEELESKTIDAADQ--TVTKVTEKAKESVTDTKDKVEKMIDHSVHHSLNR 129
+ L+ S E ++ A D+ + K +A +++ D +VE+ D L +
Sbjct 360 SNLYKSAADDSEAKSNELTRAVDELHKLLKEAGEANKTIQDHLLQVEESKDQMEKEMLEK 419
Query 130 IGLVTIKDIQNIEQLLIQLNAKVDSLVQE 158
IG + K+++N LL K L +E
Sbjct 420 IGKLE-KELENANDLLSATKRKGAILSEE 447
Score = 25.0 bits (53), Expect = 0.042
Identities = 33/157 (21%), Positives = 67/157 (43%), Gaps = 21/157 (13%)
Query 13 QEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGLGAFSRAEEEGN 72
++ K++ +KL S T+ +L+ ++ + S + KY ++ R E+E
Sbjct 217 EDVKRLNEKLKESNTTKGELQLKLDELQASDVAV----KYREK----------RLEQEKE 262
Query 73 KLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMIDHSVHHSLNRIGL 132
L + + EL++KT D+ + EK E + + K +E + + GL
Sbjct 263 LLHNQNSWLNTELKTKT----DELLALGREKGNE-ILELKCNLENKKEEVLRLEEQMNGL 317
Query 133 VTIKD--IQNIEQLLIQLNAKVDSLVQENEKLQQKLD 167
T + +++E LL +L + EK +L+
Sbjct 318 KTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELN 354
Score = 24.3 bits (51), Expect = 0.074
Identities = 38/193 (20%), Positives = 76/193 (39%), Gaps = 32/193 (17%)
Query 9 LESKQEFKQMEKKLTNSKNTEHDLEK--NDEKSKCSRK------------SGLDFRKYTK 54
+E+K KQ+++ N K + D EK N++ K + + LDF
Sbjct 740 IEAKAALKQLQEIFENYKKEKIDSEKLQNEQLEKLQEQVTDLRSQNTKISTQLDFASKRY 799
Query 55 QIWLAGLGAFSR----AEEEGNKLFDSLVKVGEELESKTID------------AADQTVT 98
++ + + R +E KL + K + + + T D + +
Sbjct 800 EMLQDNVEGYRREITSLQERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLK 859
Query 99 KVTEKAKESVTDTKDKVEKMIDHSVHHSLNRIGLVTIKDI--QNIEQLLIQLNAKVDSLV 156
K E K S + E ++ +L L TI+ I ++ + +LN++++ L
Sbjct 860 KEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLNSQIEKLE 919
Query 157 QENEKLQQKLDEK 169
E L++KL+ +
Sbjct 920 HEISHLKKKLENE 932
Score = 23.9 bits (50), Expect = 0.099
Identities = 28/132 (21%), Positives = 56/132 (42%), Gaps = 22/132 (17%)
Query 9 LESKQEFK-QMEKKLTNSKNTEHDLEKNDEKSKCSRKSGL-DFRKYTKQIWLAGLGAFSR 66
L+ EF+ Q+EKKL + + +L+ + K+ S + L + +K + A R
Sbjct 1068 LKESAEFQTQLEKKLMEVEKEKQELQDDKRKAIESMEQQLSELKKTLSTVQNEVQEALQR 1127
Query 67 A------EEEGNKLFDSLVKVGEELESK-------------TIDAADQTVTKVTEKAKES 107
A E++ + K+ E ++K + AA + V+K+T ++
Sbjct 1128 ASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMT-SIRQH 1186
Query 108 VTDTKDKVEKMI 119
+ +T K E +
Sbjct 1187 LEETTQKAESQL 1198
Score = 23.5 bits (49), Expect = 0.13
Identities = 30/159 (19%), Positives = 64/159 (40%), Gaps = 5/159 (3%)
Query 9 LESKQEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFR-KYTKQIWLAGLGAFSRA 67
+E+ Q K+ K+T+ + + + E K+ + R + K +
Sbjct 1167 VEALQAAKEQVSKMTSIRQHLEETTQKAESQLLECKASWEERERVLKDEVSKSVSRCEDL 1226
Query 68 EEEGNKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMIDHSVHHSL 127
E++ L D + K+ +++ + DA Q V+ + + ++ + I +
Sbjct 1227 EKQNRLLHDQIEKLSDKVVTSMKDAV-QAPLNVSLNEEGKSQEQILEILRFIRREKEIAE 1285
Query 128 NRIGLVTIKDI---QNIEQLLIQLNAKVDSLVQENEKLQ 163
R + ++ + Q +E L +L DSL E EK+Q
Sbjct 1286 TRFEVAQVESLRYRQRVELLERELQELQDSLNVEREKVQ 1324
Score = 22.3 bits (46), Expect = 0.31
Identities = 39/179 (22%), Positives = 77/179 (43%), Gaps = 30/179 (17%)
Query 7 KWLESKQEFKQMEKKLTNSKNTEHDL--------EKNDEKSKCSRKSGLDFRKYTKQIWL 58
K E+K++ ME+K N N L + ++ KS ++ + K K+
Sbjct 334 KLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVDELHKLLKE--- 390
Query 59 AGLGAFSRAEEEGNKLFDSLVKVGE---ELESKTIDAADQTVTKVTEKAKESVTDTKDKV 115
A E + D L++V E ++E + ++ + + K E A + ++ TK K
Sbjct 391 --------AGEANKTIQDHLLQVEESKDQMEKEMLEKIGK-LEKELENANDLLSATKRKG 441
Query 116 EKMIDHSVHHSLNRIGLVTIKDIQNIEQLLIQLNAKV---DSLV---QENEKLQQKLDE 168
+ + + +++ K ++ +L NA V D L+ QEN+++ + LDE
Sbjct 442 AILSEEEL-AAMSPTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKQENKRINKYLDE 499
Score = 20.8 bits (42), Expect = 0.97
Identities = 18/67 (27%), Positives = 31/67 (46%), Gaps = 7/67 (10%)
Query 102 EKAKESVTDTKDKVEKMIDHSVHHSLNRIGLVT-IKDIQNIEQLLIQLNAKVDSLVQENE 160
EK K ++EK + S LVT ++ QN+ L +LN +V L ++ +
Sbjct 118 EKFKVESEQQYFEIEKRLSQSQER------LVTETRECQNLRLELEKLNNQVKVLTEKTK 171
Query 161 KLQQKLD 167
+L+ D
Sbjct 172 ELETAQD 178
Score = 20.4 bits (41), Expect = 1.3
Identities = 14/35 (40%), Positives = 20/35 (57%), Gaps = 3/35 (9%)
Query 139 QNIEQLLIQLNAKVDSLVQENEKLQQ---KLDEKS 170
+ +EQ L Q+ AKV L + LQ+ +L EKS
Sbjct 1358 ERLEQNLQQMQAKVRKLELDILPLQEANAELSEKS 1392
Score = 18.9 bits (37), Expect = 4.0
Identities = 9/33 (27%), Positives = 19/33 (58%), Gaps = 0/33 (0%)
Query 136 KDIQNIEQLLIQLNAKVDSLVQENEKLQQKLDE 168
++++ + + + +LN K+ +LQ KLDE
Sbjct 210 QEVEYLTEDVKRLNEKLKESNTTKGELQLKLDE 242
Score = 18.9 bits (37), Expect = 4.0
Identities = 41/194 (21%), Positives = 75/194 (39%), Gaps = 34/194 (18%)
Query 3 TNPIKWLESKQEFKQMEKKLTNSKNTEHDLEKN----DEKSKCS---RKSGLDFRKYTKQ 55
TN ++S +E + K T + + DL+ EK K +K G ++ ++
Sbjct 1464 TNNQNLIQSLRE--DLSKARTEKEGIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQFEE 1521
Query 56 IWLAGLGAFSRAEEEGNKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKV 115
+ A + + + + V E E K + +T TK E E++ T +
Sbjct 1522 LKAQQNKAMETSTQSSGDHQEQHISVQEMQELKDTLSQSETKTKSLEGQVENLQKTLSEK 1581
Query 116 E----KMIDHSVH--HSLNRIGLVTIKDIQNIEQLLIQLNAKV----------------- 152
E + + +V L+R+ ++D EQL Q+N K
Sbjct 1582 ETEARSLQEQTVQLQSELSRLRQ-DLQDKTTEEQLRQQMNEKTWKTLALAKSKITHLSGV 1640
Query 153 -DSLVQENEKLQQK 165
D L +E E+L+Q+
Sbjct 1641 KDQLTKEIEELKQR 1654
>Q8L7E5 WPP domain-interacting tail-anchored protein 1 [Arabidopsis
thaliana]
Length=703
Score = 35.0 bits (79), Expect = 2e-05
Identities = 50/218 (23%), Positives = 90/218 (41%), Gaps = 56/218 (26%)
Query 4 NPIKWLE-SKQEFKQMEKKLTNSKNTEHDLE-------------------------KNDE 37
N ++ LE S + ++EKKL+ S+NTE +LE + D
Sbjct 231 NVLRMLEKSLAKEMELEKKLSESRNTERELEMKLYSSEQDVVYMEEVTEDAFSRWLEADN 290
Query 38 KSKCSRKSGLDFRKYTKQIWLAGLGAFSRAEEEGNKLFDSLVKVG------EELESKTID 91
++ + + + + + G+F R + +KL DS ++ +L+S
Sbjct 291 AAEVFKGTSKEMSGKLQILQFNLSGSFKREDNLKSKLVDSKERLEAKECALHKLDSSNAR 350
Query 92 AADQTVTKVTEKAKESVTDTKDKV-----------EKMIDHSVHHSLNRIGLVT------ 134
AD V + TE KES+ + ++K+ EK+ S+ LN G+ T
Sbjct 351 LADFLVAQ-TEGLKESLQEAEEKLILLNTENSTLSEKV--SSLEEQLNEYGIQTEDADAT 407
Query 135 ----IKDIQNIEQLLIQLNAKVDSLVQENEKLQQKLDE 168
I D++ I + L AK ++ +E E + L+E
Sbjct 408 SGALITDLERINEELKDKLAKTEARAEETESKCKILEE 445
>O94986 Centrosomal protein of 152 kDa [Homo sapiens]
Length=1710
Score = 34.7 bits (78), Expect = 3e-05
Identities = 23/67 (34%), Positives = 35/67 (52%), Gaps = 8/67 (12%)
Query 102 EKAKESVTDTKDKVEKMIDHSVHHSLNRIGLVTIKDIQNIEQLLIQLNAKVDSLVQENEK 161
EKAK+ D K K+EK H H L R K +E++ + N V+ L++EN
Sbjct 1176 EKAKQECQDLKGKLEKCCRHLQH--LER------KHKAVVEKIGEENNKVVEELIEENND 1227
Query 162 LQQKLDE 168
++ KL+E
Sbjct 1228 MKNKLEE 1234
Score = 26.9 bits (58), Expect = 0.010
Identities = 35/162 (22%), Positives = 67/162 (41%), Gaps = 18/162 (11%)
Query 10 ESKQEFKQMEKKLTNSKNT----------EHDLEKNDEKSKCSRKSGLDFRKYTKQIWLA 59
+ QE K+ E KL N+ + D +K + +C R QI +
Sbjct 633 QQNQELKETEGKLRNTNQDLCNQMRQMVQDFDHDKQEAVDRCERTYQQHHEAMKTQIRES 692
Query 60 GLGAFSRAEEEGNKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMI 119
L + +++ LF++ + +L S+ +D ++ VT V E E V KD +E +
Sbjct 693 LLAKHALEKQQ---LFEAYERTHLQLRSE-LDKLNKEVTAVQECYLE-VCREKDNLELTL 747
Query 120 DHSVHHSLNRIGLVTIKDIQNIEQLLIQLNAKVDSLVQENEK 161
+ + K IQ +E+ + +K+D ++ +K
Sbjct 748 RKTTEKEQQTQEKIKEKLIQQLEK---EWQSKLDQTIKAMKK 786
Score = 21.6 bits (44), Expect = 0.54
Identities = 20/84 (24%), Positives = 37/84 (44%), Gaps = 21/84 (25%)
Query 95 QTVTKVTEKAKESVTDTKDKVEKMIDHSVHHSLNRIGLVTIKD---------------IQ 139
Q + K E+ E++ + ++ E+ I + H LV IKD Q
Sbjct 242 QVLNKAKERQLENLIEKLNESERQIRYLNHQ------LVIIKDEKDGLTLSLRESQKLFQ 295
Query 140 NIEQLLIQLNAKVDSLVQENEKLQ 163
N ++ IQL A++ +L + + L+
Sbjct 296 NGKEREIQLEAQIKALETQIQALK 319
Score = 21.2 bits (43), Expect = 0.72
Identities = 37/166 (22%), Positives = 67/166 (40%), Gaps = 32/166 (19%)
Query 16 KQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGLGAFSRAEEEGNKLF 75
K+ E + K+ LE+N E K + ++ +R+ EE K
Sbjct 389 KEQEDICSRLKDHVKQLERNQEAIKLEKTEIIN--------------KLTRSLEESQKQC 434
Query 76 DSLVKVGEELESKTIDAADQTVTK-------VTEKAKESVTDTKDKV---EKMIDHSVHH 125
L++ G E + Q K + + +E +T+ KD++ E +H
Sbjct 435 AHLLQSGSVQEVAQLQFQLQQAQKAHAMSANMNKALQEELTELKDEISLYESAAKLGIHP 494
Query 126 SLNRIGLVTIKDIQNIEQLLIQ----LNAKVDSLVQE---NEKLQQ 164
S + G + I+ ++ L I+ +KV S+VQE NE+L +
Sbjct 495 S-DSEGELNIELTESYVDLGIKKVNWKKSKVTSIVQEEDPNEELSK 539
Score = 20.8 bits (42), Expect = 0.96
Identities = 17/74 (23%), Positives = 33/74 (45%), Gaps = 14/74 (19%)
Query 15 FKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGLGAFSRAEEEGNKL 74
F+++EK ++ + LE KC R RK+ + G EE NK+
Sbjct 1172 FQELEKAKQECQDLKGKLE------KCCRHLQHLERKHKAVVEKIG--------EENNKV 1217
Query 75 FDSLVKVGEELESK 88
+ L++ ++++K
Sbjct 1218 VEELIEENNDMKNK 1231
Score = 19.6 bits (39), Expect = 2.2
Identities = 23/114 (20%), Positives = 52/114 (46%), Gaps = 11/114 (10%)
Query 9 LESKQEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGLGAFSRAE 68
LE +Q F+ E+ ++ +L+K +++ ++ L+ + + L + +
Sbjct 699 LEKQQLFEAYERTHLQLRS---ELDKLNKEVTAVQECYLEVCREKDNLELTLRKTTEKEQ 755
Query 69 EEGNKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKE--SVTD---TKDKVEK 117
+ K+ + L+ ++LE + DQT+ + +K + S TD T D + K
Sbjct 756 QTQEKIKEKLI---QQLEKEWQSKLDQTIKAMKKKTLDCGSQTDQVTTSDVISK 806
>Q8IWJ2 GRIP and coiled-coil domain-containing protein 2 [Homo
sapiens]
Length=1684
Score = 34.3 bits (77), Expect = 4e-05
Identities = 21/73 (29%), Positives = 39/73 (53%), Gaps = 5/73 (7%)
Query 96 TVTKVTEKAKESVTDTKDKVEKMIDHSVHHSLNRIGLVTIKDIQNIEQLLIQLNAKVDSL 155
T+ K E S+T+ KD + +S H ++ K + E+L+++L KV+
Sbjct 580 TMLKELEGKINSLTEEKDDFINKLKNS-HEEMDNFH----KKCEREERLILELGKKVEQT 634
Query 156 VQENEKLQQKLDE 168
+Q N +L+QK++E
Sbjct 635 IQYNSELEQKVNE 647
Score = 29.6 bits (65), Expect = 0.001
Identities = 25/104 (24%), Positives = 46/104 (44%), Gaps = 9/104 (9%)
Query 16 KQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGL-GAFSRAEEEGNKL 74
K++ +KLTN N DLE+ + K ++ T Q + L + + EE+ K+
Sbjct 1170 KELNQKLTNKNNKIEDLEQEIKIQKQKQE--------TLQEEITSLQSSVQQYEEKNTKI 1221
Query 75 FDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVEKM 118
LVK +EL D + + + K + + + +V K+
Sbjct 1222 KQLLVKTKKELADSKQAETDHLILQASLKGELEASQQQVEVYKI 1265
Score = 25.8 bits (55), Expect = 0.023
Identities = 33/157 (21%), Positives = 64/157 (41%), Gaps = 14/157 (9%)
Query 12 KQEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGLGAFSRAEEEG 71
K+ Q+EKKL + +L K E + + F K +L +G+ + E
Sbjct 721 KEHITQLEKKLQLMVEEQDNLNKLLENEQVQKL----FVKTQLYGFLKEMGSEVSEDSEE 776
Query 72 NKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMIDHSVHHSLNRIG 131
+ + L VGE L ++ + + E V + + +++ + + SV
Sbjct 777 KDVVNVLQAVGESLAK-----INEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKS 831
Query 132 LVTIKDIQNIEQLLIQLNAKVDSLVQENEKLQQKLDE 168
L +++ EQ + L +++ + E E LQ L E
Sbjct 832 L-----LRDYEQEKVLLRKELEEIQSEKEALQSDLLE 863
Score = 23.1 bits (48), Expect = 0.17
Identities = 41/170 (24%), Positives = 71/170 (42%), Gaps = 30/170 (18%)
Query 2 NTNPIKWLESKQEFKQMEK-KLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAG 60
N N LE++ Q+E+ T SK+ H+ EK KC K + + +Q L
Sbjct 866 NANEKTRLENQNLLIQVEEVSQTCSKSEIHN-----EKEKCFIKEHENLKPLLEQKELRD 920
Query 61 LGAFSRAEEEGNKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMID 120
A E L DSL K +++ + + + K+ KE K+K EK
Sbjct 921 RRA------ELILLKDSLAK-SPSVKNDPLSSVKELEEKIENLEKEC----KEKEEK--- 966
Query 121 HSVHHSLNRIGLVTIKDIQNIEQLLIQLNAKVDSLVQENEKLQQKLDEKS 170
+N+I LV +K + ++ + ++ +E E L+ + D+ S
Sbjct 967 ------INKIKLVAVKAKKELD----SSRKETQTVKEELESLRSEKDQLS 1006
Score = 20.8 bits (42), Expect = 0.96
Identities = 9/30 (30%), Positives = 20/30 (67%), Gaps = 0/30 (0%)
Query 137 DIQNIEQLLIQLNAKVDSLVQENEKLQQKL 166
+I + E+L+ +LN K+ + + E L+Q++
Sbjct 1161 EIADYERLMKELNQKLTNKNNKIEDLEQEI 1190
Score = 20.4 bits (41), Expect = 1.3
Identities = 13/56 (23%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query 69 EEGNKLFDSLVKVGEELE---SKTIDAADQTVTKVTEKAKESVTDTKDKVEKMIDH 121
EE NKL ++ +LE S+ D + EK + + + +D + K++++
Sbjct 692 EENNKLSSEKKQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLEN 747
Score = 18.5 bits (36), Expect = 5.2
Identities = 32/171 (19%), Positives = 70/171 (41%), Gaps = 11/171 (6%)
Query 9 LESKQEFKQMEKKLTNSKNTEHDLEK---NDEKSKCSRKSGLDFRKYTKQIWLAGLGAFS 65
LE ++ K N K + ++EK E+ + LD K+ + L
Sbjct 164 LELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQNII 223
Query 66 RAEEEG-NKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKE------SVTDTKDKVEKM 118
A + K +SL + +L++ + + + ++ AKE + + K+ + K
Sbjct 224 EANSQHYQKNINSLQEELLQLKAIHQEEVKELMCQIEASAKEHEAEINKLNELKENLVKQ 283
Query 119 IDHSVHHSLNRIGLVTIKDIQNIEQLLIQLNAKVDSLVQENEKLQQKLDEK 169
+ S ++ + +++++ Q N L+QEN ++Q ++EK
Sbjct 284 CEAS-EKNIQKKYECELENLRKATSNANQDNQICSILLQENTFVEQVVNEK 333
Score = 18.5 bits (36), Expect = 5.2
Identities = 30/167 (18%), Positives = 64/167 (38%), Gaps = 18/167 (11%)
Query 9 LESKQEFKQMEKKLTNSKNTEHDLEKND-EKSKCSRKSGLDFRKYTKQIWLAGLGAFSRA 67
LE Q Q +KK E +L K D +++ D+ + K++ +
Sbjct 1124 LEELQVQLQKQKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKEL-------NQKL 1176
Query 68 EEEGNKLFD-----SLVKVGEELESKTIDAADQTVTKVTE---KAKESVTDTKDKVEKMI 119
+ NK+ D + K +E + I + +V + E K K+ + TK ++
Sbjct 1177 TNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSK 1236
Query 120 DHSVHHSLNRIGLVTIKDIQNIEQLLIQLNAKVDSLVQENEKLQQKL 166
H + + L +++ +Q + ++ + E K+ + L
Sbjct 1237 QAETDHLILQASLK--GELEASQQQVEVYKIQLAEITSEKHKIHEHL 1281
>P12270 Nucleoprotein TPR [Homo sapiens]
Length=2363
Score = 28.5 bits (62), Expect = 0.003
Identities = 40/180 (22%), Positives = 74/180 (41%), Gaps = 27/180 (15%)
Query 12 KQEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGLGAFSRAEEEG 71
+ E ++KKL N H L +N + K LD + L A++E
Sbjct 845 EHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTE---TNLHLNTKELLKNAQKEI 901
Query 72 NKLFDSL----VKVGEELESKT-------IDAADQTVTKVTEKAKESVTDTKDKVEKMID 120
L L V+V + +T + D V+++ + +E V D K++++
Sbjct 902 ATLKQHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQL-RQTEEQVNDLKERLKTSTS 960
Query 121 H---------SVHHSLNRIGLVTIKDIQNIEQLL---IQLNAKVDSLVQENEKLQQKLDE 168
+ S+ SLN+ VT + +NIE L + +++ + E EK +Q+L +
Sbjct 961 NVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQD 1020
Score = 28.1 bits (61), Expect = 0.004
Identities = 31/154 (20%), Positives = 63/154 (41%), Gaps = 17/154 (11%)
Query 12 KQEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGLGA-------F 64
K+E ++E+++ K + L+K+ E K + + ++ + L A +
Sbjct 230 KEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLY 289
Query 65 SRAEEEGNKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMIDHSVH 124
A ++ + L + EEL + K +A +++ D +VE+ D
Sbjct 290 KSAADDSEAKSNELTRAVEELHK---------LLKEAGEANKAIQDHLLEVEQSKDQMEK 340
Query 125 HSLNRIGLVTIKDIQNIEQLLIQLNAKVDSLVQE 158
L +IG + K+++N LL K L +E
Sbjct 341 EMLEKIGRLE-KELENANDLLSATKRKGAILSEE 373
Score = 25.4 bits (54), Expect = 0.031
Identities = 15/62 (24%), Positives = 32/62 (52%), Gaps = 5/62 (8%)
Query 102 EKAKESVTDTKDKVEKMIDHSVHHSLNRIGLVTIKDIQNIEQLLIQLNAKVDSLVQENEK 161
EK K ++EK + HS +N ++ Q++ L +LN ++ +L ++N++
Sbjct 44 EKFKVESEQQYFEIEKRLSHSQERLVNE-----TRECQSLRLELEKLNNQLKALTEKNKE 98
Query 162 LQ 163
L+
Sbjct 99 LE 100
Score = 24.3 bits (51), Expect = 0.074
Identities = 17/44 (39%), Positives = 22/44 (50%), Gaps = 4/44 (9%)
Query 83 EELESKTIDAADQ----TVTKVTEKAKESVTDTKDKVEKMIDHS 122
EE E TI+A+DQ TV K +SVT + E M + S
Sbjct 1833 EEEEDSTIEASDQVSDDTVEMPLPKKLKSVTPVGTEEEVMAEES 1876
Score = 22.3 bits (46), Expect = 0.31
Identities = 29/96 (30%), Positives = 45/96 (47%), Gaps = 10/96 (10%)
Query 6 IKWLESKQEFKQMEKKLTNSKNTEHDLE---KNDEKSKCSRKSGLDFRKYTKQIWLAGLG 62
+K+ E + E EK+L +S+NT + E K DE R+ G + + +
Sbjct 176 VKYREKRLE---QEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNL-ENKKE 231
Query 63 AFSRAEEEGNKLFDS---LVKVGEELESKTIDAADQ 95
SR EE+ N L S L K E+L +K +A +Q
Sbjct 232 EVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQ 267
Score = 21.9 bits (45), Expect = 0.41
Identities = 35/160 (22%), Positives = 70/160 (44%), Gaps = 39/160 (24%)
Query 9 LESKQEFKQMEKKLTNSKNTEHDLEKNDEKSKCSRKSGLDFRKYTKQIWLAGLGAFSRAE 68
+ES+Q++ ++EK+L++S+ E+ +++ + L+ K Q+ +A
Sbjct 48 VESEQQYFEIEKRLSHSQ------ERLVNETRECQSLRLELEKLNNQL---------KAL 92
Query 69 EEGNKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMIDHSVHHSLN 128
E NK ELE A D+ + + T TK+++E + L
Sbjct 93 TEKNK----------ELEI----AQDRNIA-----IQSQFTRTKEELE-----AEKRDLI 128
Query 129 RIGLVTIKDIQNIEQLLIQLNAKVDSLVQENEKLQQKLDE 168
R ++++ + + + +LN K+ +LQ KLDE
Sbjct 129 RTNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDE 168
Score = 21.6 bits (44), Expect = 0.55
Identities = 37/219 (17%), Positives = 81/219 (37%), Gaps = 61/219 (28%)
Query 7 KWLESKQEFKQMEKKLTNSKNTEHDL--------EKNDEKSKCSRKSGLDFRKYTKQI-- 56
K E+K++ ME+K N N L + ++ KS ++ + K K+
Sbjct 260 KLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGE 319
Query 57 ----------------------WLAGLGAFSRAEEEGNKLFDSLVKVGEELESKTIDAAD 94
L +G + E N L + + G L + + A
Sbjct 320 ANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMS 379
Query 95 QTVTKVTEKAK---------ESVTDTKDK--VEKMIDHSVHHSLNRIGLVTIKDI----- 138
T V + K + +T+D+ +EK+ + ++ L+ I +K++
Sbjct 380 PTAAAVAKIVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEI----VKEVEAKAP 435
Query 139 ---------QNIEQLLIQLNAKVDSLVQENEKLQQKLDE 168
+ ++ + L+ K++ ++E ++LQ+ D+
Sbjct 436 ILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTDK 474
Score = 21.6 bits (44), Expect = 0.55
Identities = 28/156 (18%), Positives = 65/156 (42%), Gaps = 30/156 (19%)
Query 9 LESKQEFKQMEKKLTNSKNTEHDLEK-NDEKSKCSRKSGLDFRKYTKQIWLAGLGAFSRA 67
+E+K KQ+++ N K + + EK +E+ + ++ D R +I S
Sbjct 666 IEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKLQEQVTDLRSQNTKI--------STQ 717
Query 68 EEEGNKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMIDHSVHHSL 127
+ +K ++ L ++ + +T + E+ + +T T K E++I+
Sbjct 718 LDFASKRYEML--------QDNVEGYRREITSLHER-NQKLTATTQKQEQIIN------- 761
Query 128 NRIGLVTIKDIQNIEQLLIQLNAKVDSLVQENEKLQ 163
+D++ + L + ++L +E E L+
Sbjct 762 -----TMTQDLRGANEKLAVAEVRAENLKKEKEMLK 792
Score = 21.6 bits (44), Expect = 0.55
Identities = 26/132 (20%), Positives = 55/132 (42%), Gaps = 22/132 (17%)
Query 9 LESKQEFK-QMEKKLTNSKNTEHDLEKNDEKSKCSRKSGL-DFRKYTKQIWLAGLGAFSR 66
L+ EF+ Q+EKKL + + +L+ + ++ S + L + +K + A R
Sbjct 994 LKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKKTLSSVQNEVQEALQR 1053
Query 67 A------EEEGNKLFDSLVKVGEELESK-------------TIDAADQTVTKVTEKAKES 107
A E++ + K+ E ++K + AA + V+K+ ++
Sbjct 1054 ASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMA-SVRQH 1112
Query 108 VTDTKDKVEKMI 119
+ +T K E +
Sbjct 1113 LEETTQKAESQL 1124
Score = 20.4 bits (41), Expect = 1.3
Identities = 11/25 (44%), Positives = 14/25 (56%), Gaps = 0/25 (0%)
Query 139 QNIEQLLIQLNAKVDSLVQENEKLQ 163
Q +E L +L DSL E EK+Q
Sbjct 1226 QRVELLERELQELQDSLNAEREKVQ 1250
Score = 20.4 bits (41), Expect = 1.3
Identities = 23/81 (28%), Positives = 38/81 (47%), Gaps = 9/81 (11%)
Query 93 ADQTVTKVTEKAKESVTDTKDKVEKMIDHSVHHSLNRIGLVTIKDIQNIEQLLIQLNAKV 152
A++ +VT K + K E M +V N++ ++ + +EQ L Q+ AKV
Sbjct 1244 AEREKVQVTAKTMAQHEELMKKTETM---NVVMETNKM---LREEKERLEQDLQQMQAKV 1297
Query 153 DSLVQENEKLQQ---KLDEKS 170
L + LQ+ +L EKS
Sbjct 1298 RKLELDILPLQEANAELSEKS 1318
Score = 18.9 bits (37), Expect = 4.0
Identities = 10/34 (29%), Positives = 18/34 (53%), Gaps = 6/34 (18%)
Query 95 QTVTKVTEKAKESVTDTKDKVEKMI---DHSVHH 125
QT+ + E+ S T+TK ++ I +H + H
Sbjct 820 QTIQGILER---SETETKQRLSSQIEKLEHEISH 850
>Q8JHV6 Laminin subunit beta-4 [Danio rerio]
Length=1827
Score = 25.0 bits (53), Expect = 0.042
Identities = 13/46 (28%), Positives = 26/46 (57%), Gaps = 4/46 (9%)
Query 127 LNRIGLVTIKDIQNIEQLLIQLNAKV----DSLVQENEKLQQKLDE 168
LNR L+ +K+I+ +L+ K+ D Q N+ +++K++E
Sbjct 1628 LNRTELINVKEIEKALNDTAKLHDKIFNDLDEAEQNNDVIREKVNE 1673
Score = 23.9 bits (50), Expect = 0.098
Identities = 24/96 (25%), Positives = 43/96 (45%), Gaps = 11/96 (11%)
Query 76 DSLVKVGEELESKTIDAADQTVTKVTE---KAKESVTDTKDKVEKMIDHSVHHSLNRIGL 132
D+ ++ E+ S D A+ + K+ K ++ TDTK +EK+ + L
Sbjct 1508 DAQLRNASEMTSYVKDQAENMMDKINRTKTKYEQEKTDTKALIEKVKTYLQDE------L 1561
Query 133 VTIKDIQNIEQ--LLIQLNAKVDSLVQENEKLQQKL 166
V +DI+ + L IQL D + E +++ L
Sbjct 1562 VKPEDIEKLANAVLSIQLPKSPDEIKDMIEDIKKIL 1597
Score = 20.8 bits (42), Expect = 0.96
Identities = 15/56 (27%), Positives = 29/56 (52%), Gaps = 2/56 (4%)
Query 64 FSRAEEEGNKLFDSLVKVGEELESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMI 119
F++ ++ ++ DS KV E K +A+ +T KVT + + DK+E+ +
Sbjct 1384 FNKIKKFYDEFTDSEKKV--EAAKKVQEASRKTREKVTLELAKCQIGEMDKLERKV 1437
Score = 19.6 bits (39), Expect = 2.3
Identities = 9/25 (36%), Positives = 12/25 (48%), Gaps = 0/25 (0%)
Query 14 EFKQMEKKLTNSKNTEHDLEKNDEK 38
EF EKK+ +K + K EK
Sbjct 1393 EFTDSEKKVEAAKKVQEASRKTREK 1417
Score = 19.6 bits (39), Expect = 2.3
Identities = 20/87 (23%), Positives = 37/87 (43%), Gaps = 4/87 (5%)
Query 83 EELESKTIDAADQTVTKVTEKAKESVTDTKDKVEKMIDHSVHHS--LNRIGLVTIKDIQN 140
+E + ++ + K EKA DK+ +D + ++ + T ++N
Sbjct 1621 KERAKEILNRTELINVKEIEKALNDTAKLHDKIFNDLDEAEQNNDVIREKVNETEPKLKN 1680
Query 141 IEQLLIQLNAKVDSLVQENEKLQQKLD 167
IE L AK +L+ E E L+ K +
Sbjct 1681 IEDHLNLTRAK--TLLDEIEALKNKTE 1705
Lambda K H a alpha
0.311 0.127 0.342 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 1757166
Database: a21e305bf7a095e41a6961f028396b10.SwissProt.fasta
Posted date: May 20, 2024 9:49 PM
Number of letters in database: 15,138
Number of sequences in database: 15
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
Loading
Data ...
