BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: b19074d01be514d6b0dfa95864f7f941.SwissProt.fasta
15 sequences; 8,955 total letters
Query= ACIAD1606
Length=548
Score E
Sequences producing significant alignments: (Bits) Value
P39062 Acetyl-coenzyme A synthetase [Bacillus subtilis (strain 168)] 348 9e-117
Q7TN78 Acyl-coenzyme A synthetase ACSM4, mitochondrial [Rattus no... 306 4e-100
Q80W40 Acyl-coenzyme A synthetase ACSM4, mitochondrial [Mus muscu... 301 2e-98
P0C7M7 Acyl-coenzyme A synthetase ACSM4, mitochondrial [Homo sapi... 290 6e-94
A0KY83 Acetyl-coenzyme A synthetase [Shewanella sp. (strain ANA-3)] 283 7e-91
Q6NUN0 Acyl-coenzyme A synthetase ACSM5, mitochondrial [Homo sapi... 281 1e-90
Q6SKG1 Acyl-coenzyme A synthetase ACSM3, mitochondrial [Rattus no... 281 1e-90
Q8EDK3 Acetyl-coenzyme A synthetase [Shewanella oneidensis (strai... 282 2e-90
Q0HTY6 Acetyl-coenzyme A synthetase [Shewanella sp. (strain MR-7)] 282 2e-90
Q0HHN4 Acetyl-coenzyme A synthetase [Shewanella sp. (strain MR-4)] 281 4e-90
Q3UNX5 Acyl-coenzyme A synthetase ACSM3, mitochondrial [Mus muscu... 277 4e-89
Q08AH1 Acyl-coenzyme A synthetase ACSM1, mitochondrial [Homo sapi... 272 2e-87
Q68CK6 Acyl-coenzyme A synthetase ACSM2B, mitochondrial [Homo sap... 267 2e-85
Q08AH3 Acyl-coenzyme A synthetase ACSM2A, mitochondrial [Homo sap... 267 3e-85
Q91VA0 Acyl-coenzyme A synthetase ACSM1, mitochondrial [Mus muscu... 265 1e-84
>P39062 Acetyl-coenzyme A synthetase [Bacillus subtilis (strain
168)]
Length=572
Score = 348 bits (894), Expect = 9e-117
Identities = 217/549 (40%), Positives = 312/549 (57%), Gaps = 13/549 (2%)
Query 3 DYQTVATSFDFHRAANEMLSGSLDQVNACYECCDRHAES-NPEKIALYWQGKDGRQYQYT 61
+Y+ FD+ A ++NA YE DRHAES K+ALY++ R +YT
Sbjct 17 NYEETYRHFDWAEAEKHFSWHETGKLNAAYEAIDRHAESFRKNKVALYYKDAK-RDEKYT 75
Query 62 FAQLQKWSSQFANFLKSQG-VQTGDRISGLLPRTPELLVVILGAWRIGAVYQPLFTAFGP 120
F ++++ S++ N L+ G V+ GDR+ +PR+PEL ++LGA +IGA+ PLF AF
Sbjct 76 FKEMKEESNRAGNVLRRYGNVEKGDRVFIFMPRSPELYFIMLGAIKIGAIAGPLFEAFME 135
Query 121 KAIEHRVQLAKSKLVVT--DLGNRSKLDEVAHCPPIMTVIGEKDHAVNDQDLNFWKQVSQ 178
A++ R++ +++K+VVT +L R +D++ H + V GE + N +N+ + Q
Sbjct 136 GAVKDRLENSEAKVVVTTPELLERIPVDKLPHLQHVFVVGGEAESGTNI--INYDEAAKQ 193
Query 179 ASDHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKALIAFGHYMKDAIGLRTDDVFWNL 238
S D+ D + FLL +TSG+TG K + +A+I K + L+ +D++W
Sbjct 194 ESTRLDIEWMDKKDGFLLHYTSGSTGTPKGVLHVHEAMIQQYQTGKWVLDLKEEDIYWCT 253
Query 239 ADPGWAYGLYYAITGPLLLGHATLFYEGGFSIDSLCQIIEDYKITNLAGAPTAYRMMMAA 298
ADPGW G Y I P L G + G FS +S IE + APTA+RM+M A
Sbjct 254 ADPGWVTGTVYGIFAPWLNGATNVIVGGRFSPESWYGTIEQLGVNVWYSAPTAFRMLMGA 313
Query 299 DPAKIACLK-GKLRVISSAGEPLNPEVFRWFKHTLDAPIFDHYGQTEVG-MVVCNHHGLS 356
A LR + S GEPLNPEV RW + I D + TE G ++CN+ +
Sbjct 314 GDEMAAKYDLTSLRHVLSVGEPLNPEVIRWGHKVFNKRIHDTWWMTETGSQLICNYPCM- 372
Query 357 HDVRAGTAGFASPGYRVAVVDEQGNELPADTAGILAVDIQKSPMMW-FGGYQESRKSPFL 415
D++ G+ G PG A+VD QGNELP G LA+ MM E +S F+
Sbjct 373 -DIKPGSMGKPIPGVEAAIVDNQGNELPPYRMGNLAIKKGWPSMMHTIWNNPEKYESYFM 431
Query 416 KH-YYLTGDTAELHADGSMSFVGRSDDVITTSGYRIGPFDVESALIEHQAVIEAAVIGVP 474
+Y++GD+A + +G F GR DDVI TSG R+GPF+VES L+EH A+ EA VIG P
Sbjct 432 PGGWYVSGDSAYMDEEGYFWFQGRVDDVIMTSGERVGPFEVESKLVEHPAIAEAGVIGKP 491
Query 475 DPERTEIVKAFVILTAQTSPSEQLAEELRQFVKKRLSAHAYPRQVEFVTELPKTPSGKIQ 534
DP R EI+KAF+ L PS++L EE+R FVK+ L+AHA PR++EF +LPKT SGKI
Sbjct 492 DPVRGEIIKAFIALREGFEPSDKLKEEIRLFVKQGLAAHAAPREIEFKDKLPKTRSGKIM 551
Query 535 RFLLRNQEI 543
R +L+ E+
Sbjct 552 RRVLKAWEL 560
>Q7TN78 Acyl-coenzyme A synthetase ACSM4, mitochondrial [Rattus
norvegicus]
Length=580
Score = 306 bits (783), Expect = 4e-100
Identities = 188/510 (37%), Positives = 283/510 (55%), Gaps = 15/510 (3%)
Query 43 PEKIALYWQGKDGRQYQYTFAQLQKWSSQFANFL-KSQGVQTGDRISGLLPRTPELLVVI 101
P AL+W G + +++F +L S + AN L K G+Q GDR++ +LPR PE ++
Sbjct 72 PANPALWWVNGKGDEVKWSFQELGSLSRKAANVLTKPCGLQRGDRVAVILPRIPEWWLIN 131
Query 102 LGAWRIGAVYQPLFTAFGPKAIEHRVQLAKSKLVVTDLGNRSKLDEVA-HCPPIMTVIGE 160
+ R G V+ P K I +R+Q +K+K +V +D +A CP + T +
Sbjct 132 VACMRTGLVFMPGTIQLTRKDILYRLQASKAKCIVASEEVAPAVDSIASECPNLKTKLLV 191
Query 161 KDHAVNDQDLNFWKQVSQASDHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKAL-IAF 219
H D L+F + + AS+ + V Q+P + FTSGTTG K + +L I +
Sbjct 192 SPHRW-DGWLSFQELLQSASEEHNCVQTGSQEPMAIYFTSGTTGSPKMAQHSQSSLGIGY 250
Query 220 GHYMKDAIGLRTDDVFWNLADPGWAYGLYYAITGPLLLGHATLFYE-GGFSIDSLCQIIE 278
+ + L + D+ WN++D GW ++ L G + F+ D+ +
Sbjct 251 ALCGRYWLDLTSSDIMWNMSDTGWIKAAIGSVFSTWLRGACVFVHRMAQFNTDTFLDTLT 310
Query 279 DYKITNLAGAPTAYRMMMAADPAKIACLKGKLRVISSAGEPLNPEVFRWFKHTLDAPIFD 338
Y IT L APT YRM++ D + + LR + GEPLNPEV +K +++
Sbjct 311 SYPITTLCSAPTVYRMLVQQDLKRYQFKR--LRHCLTGGEPLNPEVLEQWKAQTGLELYE 368
Query 339 HYGQTEVGMVVCNHHGLSHDVRAGTAGFASPGYRVAVVDEQGNELPADTAGILAVDIQKS 398
YGQTEVG++ N G +++ G+ G Y V ++DE GN LP+ G +A+ +
Sbjct 369 GYGQTEVGIICANRKG--EEIKPGSMGKGVVPYDVQIIDEHGNILPSGKEGEIALRLGSD 426
Query 399 -PMMWFGGY---QESRKSPFLKHYYLTGDTAELHADGSMSFVGRSDDVITTSGYRIGPFD 454
P +F Y E + +++Y+TGD + DG + FVGR+DDVI +SGYRIGPF+
Sbjct 427 RPFCFFSEYVDNPEKTDATIRRNFYITGDRGVMDDDGYLWFVGRADDVIISSGYRIGPFE 486
Query 455 VESALIEHQAVIEAAVIGVPDPERTEIVKAFVILTA--QTSPSEQLAEELRQFVKKRLSA 512
VESALIEH AV+E+AV+ PDP R E+VKAF++L A ++S E+L EL+ VK +
Sbjct 487 VESALIEHPAVVESAVVSSPDPIRGEVVKAFIVLAAPFKSSNREKLTAELQDHVKNSTAP 546
Query 513 HAYPRQVEFVTELPKTPSGKIQRFLLRNQE 542
+ YPR+VEFV ELPKT +GKI+R +LR+QE
Sbjct 547 YKYPRKVEFVQELPKTITGKIKRNVLRDQE 576
>Q80W40 Acyl-coenzyme A synthetase ACSM4, mitochondrial [Mus musculus]
Length=580
Score = 301 bits (771), Expect = 2e-98
Identities = 191/513 (37%), Positives = 279/513 (54%), Gaps = 21/513 (4%)
Query 43 PEKIALYWQGKDGRQYQYTFAQLQKWSSQFANFL-KSQGVQTGDRISGLLPRTPELLVVI 101
P AL+W G + +++F +L S + AN L K G+Q GDR++ +LPR PE ++
Sbjct 72 PANPALWWVNGKGDEVKWSFQELGSLSRKAANVLTKPCGLQRGDRVAVILPRIPEWWLIN 131
Query 102 LGAWRIGAVYQPLFTAFGPKAIEHRVQLAKSKLVVTDLGNRSKLDE-VAHCPPIMTVIGE 160
+ R G V+ P K I +R+Q +K+K +V +D V+ CP + T +
Sbjct 132 VACMRTGLVFMPGTIQLTRKDILYRLQASKAKCIVASEEVAPAVDSIVSECPSLKTKLLV 191
Query 161 KDHAVNDQDLNFWKQVSQASDHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKAL---- 216
H D LNF + + AS+ + V Q+P + FTSGTTG K + +L
Sbjct 192 SPHHW-DGWLNFQELLQSASEEHNCVETGSQEPMAIYFTSGTTGSPKMAQHSQGSLGIGY 250
Query 217 IAFGHYMKDAIGLRTDDVFWNLADPGWAYGLYYAITGPLLLGHATLFYE-GGFSIDSLCQ 275
G Y D L + D+ WN++D GW ++ L G + F D
Sbjct 251 TLCGRYWLD---LTSSDIMWNMSDTGWIKAAIGSVFSTWLRGACVFVHRMAQFDTDIFLD 307
Query 276 IIEDYKITNLAGAPTAYRMMMAADPAKIACLKGKLRVISSAGEPLNPEVFRWFKHTLDAP 335
+ Y IT L APT YRM++ D + + LR + GEPLNPEV +K
Sbjct 308 TLTTYPITTLCSAPTVYRMLVQKDLKRYQFKR--LRHCLTGGEPLNPEVLEQWKMQTGLE 365
Query 336 IFDHYGQTEVGMVVCNHHGLSHDVRAGTAGFASPGYRVAVVDEQGNELPADTAGILAVDI 395
+++ YGQTEVG++ N G + ++ G+ G Y V ++DE GN LP+ G +A+ +
Sbjct 366 LYEGYGQTEVGIICANRKGEA--IKPGSMGKGVVPYDVQIIDENGNILPSGKEGEIALRL 423
Query 396 QKS-PMMWFGGY---QESRKSPFLKHYYLTGDTAELHADGSMSFVGRSDDVITTSGYRIG 451
+ P +F Y E + +++Y+TGD + DG FVGR+DDVI +SGYRIG
Sbjct 424 KSDRPFCFFSEYVDNPEKTDATIRRNFYVTGDRGVMDDDGYFWFVGRADDVIISSGYRIG 483
Query 452 PFDVESALIEHQAVIEAAVIGVPDPERTEIVKAFVILTA--QTSPSEQLAEELRQFVKKR 509
PF+VESALIEH AV+E+AV+ PDP R E+VKAF++L A + S E+L EL+ VK
Sbjct 484 PFEVESALIEHPAVVESAVVSSPDPIRGEVVKAFIVLAAPYKCSNREKLTAELQDHVKNS 543
Query 510 LSAHAYPRQVEFVTELPKTPSGKIQRFLLRNQE 542
+ + YPR+VEFV ELPKT +GKI+R +LR+QE
Sbjct 544 TAPYKYPRKVEFVQELPKTITGKIKRNVLRDQE 576
>P0C7M7 Acyl-coenzyme A synthetase ACSM4, mitochondrial [Homo
sapiens]
Length=580
Score = 290 bits (741), Expect = 6e-94
Identities = 187/517 (36%), Positives = 279/517 (54%), Gaps = 29/517 (6%)
Query 43 PEKIALYWQGKDGRQYQYTFAQLQKWSSQFANFL-KSQGVQTGDRISGLLPRTPELLVVI 101
P AL+W G + +++F +L S + AN L K G+Q GDR++ +LPR PE +V
Sbjct 72 PANPALWWVNGKGDEVKWSFRELGSLSRKAANVLTKPCGLQRGDRLAVILPRIPEWWLVN 131
Query 102 LGAWRIGAVYQPLFTAFGPKAIEHRVQLAKSKLVVTDLGNRSKLDEVA-HCPPIMTVIGE 160
+ R G ++ P K I +R++ +K+K +V ++ + CP + T +
Sbjct 132 VACIRTGIIFMPGTIQLTAKDILYRLRASKAKCIVASEEVAPAVESIVLECPDLKTKL-- 189
Query 161 KDHAVNDQDLNFWKQVSQ----ASDHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKAL 216
V+ Q N W + AS+ V Q+P + FTSGTTG K + +L
Sbjct 190 ---LVSPQSWNGWLSFQELFQFASEEHSCVETGSQEPMTIYFTSGTTGFPKMAQHSQSSL 246
Query 217 -IAF---GHYMKDAIGLRTDDVFWNLADPGWAYGLYYAITGPLLLGHATLFYE-GGFSID 271
I F G Y D L++ D+ WN++D GW ++ L G + F D
Sbjct 247 GIGFTLCGRYWLD---LKSSDIIWNMSDTGWVKAAIGSVFSSWLCGACVFVHRMAQFDTD 303
Query 272 SLCQIIEDYKITNLAGAPTAYRMMMAADPAKIACLKGKLRVISSAGEPLNPEVFRWFKHT 331
+ + Y IT L PT YRM++ D + LR + GEPLNPEV ++
Sbjct 304 TFLDTLTTYPITTLCSPPTVYRMLVQKDLKRYKFKS--LRHCLTGGEPLNPEVLEQWRVQ 361
Query 332 LDAPIFDHYGQTEVGMVVCNHHGLSHDVRAGTAGFASPGYRVAVVDEQGNELPADTAGIL 391
+++ YGQTEVGM+ N G +++ G+ G Y V ++DE GN LP G +
Sbjct 362 TGLELYEGYGQTEVGMICANQKG--QEIKPGSMGKGMLPYDVQIIDENGNVLPPGKEGEI 419
Query 392 AVDIQKS-PMMWFGGYQESRK---SPFLKHYYLTGDTAELHADGSMSFVGRSDDVITTSG 447
A+ ++ + P +F Y ++ + + +Y+TGD + +DG FVGR+DDVI +SG
Sbjct 420 ALRLKPTRPFCFFSKYVDNPQKTAATIRGDFYVTGDRGVMDSDGYFWFVGRADDVIISSG 479
Query 448 YRIGPFDVESALIEHQAVIEAAVIGVPDPERTEIVKAFVILTA--QTSPSEQLAEELRQF 505
YRIGPF+VESALIEH AV+E+AV+ PD R E+VKAFV+L A ++ E+L EL+
Sbjct 480 YRIGPFEVESALIEHPAVVESAVVSSPDQIRGEVVKAFVVLAAPFKSYNPEKLTLELQDH 539
Query 506 VKKRLSAHAYPRQVEFVTELPKTPSGKIQRFLLRNQE 542
VKK + + YPR+VEFV ELPKT +GKI+R +LR+QE
Sbjct 540 VKKSTAPYKYPRKVEFVQELPKTITGKIKRNVLRDQE 576
>A0KY83 Acetyl-coenzyme A synthetase [Shewanella sp. (strain ANA-3)]
Length=650
Score = 283 bits (725), Expect = 7e-91
Identities = 194/562 (35%), Positives = 286/562 (51%), Gaps = 34/562 (6%)
Query 9 TSFDFHRAA-NEMLSGSLDQVNACYECCDRHAESNPEKIALYWQGKDG-RQYQYTFAQLQ 66
T+FD H + N G+L NA C DRH + +++A+ W+G + Q Q T+ +L
Sbjct 58 TTFDDHNLSINWFYDGTL---NASANCLDRHLAEHSDRVAIIWEGDNASEQRQITYGELH 114
Query 67 KWSSQFANFLKSQGVQTGDRISGLLPRTPELLVVILGAWRIGAVYQPLFTAFGPKAIEHR 126
+FAN L+SQGV+ GD ++ +P PE V +L RIGAV+ +F F P +I R
Sbjct 115 TQVCKFANALRSQGVRRGDIVTIYMPMVPEAAVAMLACARIGAVHSVVFGGFSPDSIASR 174
Query 127 VQLAKSKLVVT-DLGNRS--------KLDEVAHCPPIMTV--------IGEKDHAVNDQD 169
V KSK+V+T D G R +D+ P + +V G K V +D
Sbjct 175 VIDGKSKVVITADEGMRGGRAIPLKRNIDDALKHPDVTSVEKVIVLKRTGGKVDWVEGRD 234
Query 170 LNFWKQVSQASDHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKALIAFGHYMKDAI-G 228
+ + V AS+HC + + P L++TSG+TG K + + + + +
Sbjct 235 VWWHSLVETASEHCAIEEMGAEDPLFLLYTSGSTGNPKGVLHTTGGYMVYASMTHEYVFD 294
Query 229 LRTDDVFWNLADPGWAYGLYYAITGPLLLGHATLFYEGGFSIDS---LCQIIEDYKITNL 285
+ +++W AD GW G Y + GPL G L +EG + S L ++I+ +K+ L
Sbjct 295 YKPGEIYWCTADVGWITGHSYMVYGPLANGATVLIHEGIPNYPSPARLGEMIDRHKVNIL 354
Query 286 AGAPTAYRMMMAADPAKIACLKGK-LRVISSAGEPLNPEVFRWFKHTLD---APIFDHYG 341
APT R +MA G LR++ S GEP+NPE +RW+ + PI D +
Sbjct 355 YTAPTLIRALMAEGKQHFDKYDGSSLRIMGSVGEPINPEAWRWYHEVIGHEHCPIVDTWW 414
Query 342 QTEVGMVVCNHHGLSHDVRAGTAGFASPGYRVAVVDEQGNELPADTAG-ILAVDIQKSPM 400
QTE G ++ + D + G+A G + A+VD GN L T G ++ +D M
Sbjct 415 QTETGGILITPLPGATDTKPGSATRPFFGVQPALVDNMGNILEGATEGNLVLLDSWPGQM 474
Query 401 MWFGGYQESRKSPFLKHY---YLTGDTAELHADGSMSFVGRSDDVITTSGYRIGPFDVES 457
G E + K + Y TGD A DG GR DDVI SG+R+G +VES
Sbjct 475 RTVYGDHERFVLTYFKTFRGMYFTGDGARRDEDGYYWITGRVDDVINVSGHRLGTAEVES 534
Query 458 ALIEHQAVIEAAVIGVPDPERTEIVKAFVILTAQTSPSEQLAEELRQFVKKRLSAHAYPR 517
AL+ H+ V EAAV+G P + + + A+V LT T SE+L +ELRQ+V+K + A A P
Sbjct 535 ALVSHELVAEAAVVGYPHDIKGQGIYAYVTLTRGTEESEELRQELRQWVRKEIGALATPD 594
Query 518 QVEFVTELPKTPSGKIQRFLLR 539
+++ T LPKT SGKI R LR
Sbjct 595 LIQWATGLPKTRSGKIMRRFLR 616
>Q6NUN0 Acyl-coenzyme A synthetase ACSM5, mitochondrial [Homo
sapiens]
Length=579
Score = 281 bits (719), Expect = 1e-90
Identities = 184/520 (35%), Positives = 283/520 (54%), Gaps = 22/520 (4%)
Query 39 AESNPEKIALYWQGKDGRQYQYTFAQLQKWSSQFANFLKSQ-GVQTGDRISGLLPRTPEL 97
A P A +W G + +++F +L K S + AN L G+Q GDR+ +LPR PE
Sbjct 69 AGHRPPNPAFWWVNGTGAEIKWSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEW 128
Query 98 LVVILGAWRIGAVYQPLFTAFGPKAIEHRVQLAKSKLVVTDLGNRSKLDEV-AHCPPIMT 156
+V + R G V P T K +++R+Q +++K ++T ++D + A CP + T
Sbjct 129 WLVSVACMRTGTVMIPGVTQLTEKDLKYRLQASRAKSIITSDSLAPRVDAISAECPSLQT 188
Query 157 VIGEKDHAVNDQDLNFWKQVSQASDHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKAL 216
+ D + LNF + + +AS + + + P + FTSGTTG K +E +
Sbjct 189 KLLVSDSS-RPGWLNFRELLREASTEHNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSY 247
Query 217 -IAFGHYMKDAIGLRTDDVFWNLADPGW---AYGLYYAI-TGPLLLGHATLFYEGGFSID 271
+ F + + L D+FWN D GW A+ L+ A G + H + ++
Sbjct 248 GLGFVASGRRWVALTESDIFWNTTDTGWVKAAWTLFSAWPNGSCIFVHELPRVDAKVILN 307
Query 272 SLCQIIEDYKITNLAGAPTAYRMMMAADPAKIACLKGKLRVISSAGEPLNPEVFRWFKHT 331
+L + + IT L PT +R+++ D + LR + GE LNP+V +KH
Sbjct 308 TLSK----FPITTLCCVPTIFRLLVQEDLTRYQFQS--LRHCLTGGEALNPDVREKWKHQ 361
Query 332 LDAPIFDHYGQTEVGMVVCNHHGLSHDVRAGTAGFASPGYRVAVVDEQGNELPADTAGIL 391
+++ YGQ+E ++ N G+ +++G+ G ASP Y V +VD++GN LP G +
Sbjct 362 TGVELYEGYGQSETVVICANPKGMK--IKSGSMGKASPPYDVQIVDDEGNVLPPGEEGNV 419
Query 392 AVDIQKS-PMMWFGGYQESRKSPFLKH---YYLTGDTAELHADGSMSFVGRSDDVITTSG 447
AV I+ + P +F Y ++ + +Y+TGD A + DG F+GR+DDVI +S
Sbjct 420 AVRIRPTRPFCFFNCYLDNPEKTAASEQGDFYITGDRARMDKDGYFWFMGRNDDVINSSS 479
Query 448 YRIGPFDVESALIEHQAVIEAAVIGVPDPERTEIVKAFVILTAQTS--PSEQLAEELRQF 505
YRIGP +VESAL EH AV+E+AV+ PDP R E+VKAF++LT S E L EL++
Sbjct 480 YRIGPVEVESALAEHPAVLESAVVSSPDPIRGEVVKAFIVLTPAYSSHDPEALTRELQEH 539
Query 506 VKKRLSAHAYPRQVEFVTELPKTPSGKIQRFLLRNQEIAK 545
VK+ + + YPR+V FV+ELPKT SGKIQR LR+QE K
Sbjct 540 VKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKLRSQEWGK 579
>Q6SKG1 Acyl-coenzyme A synthetase ACSM3, mitochondrial [Rattus
norvegicus]
Length=580
Score = 281 bits (718), Expect = 1e-90
Identities = 187/516 (36%), Positives = 274/516 (53%), Gaps = 26/516 (5%)
Query 41 SNPEKIALYWQGKDGRQYQYTFAQLQKWSSQFANFL-KSQGVQTGDRISGLLPRTPELLV 99
SNP A +W +G++ +++F +L S +FAN L ++ +Q GDR+ +LP+ PE +
Sbjct 73 SNP---AFWWVDGNGKEVRWSFEELGSLSRKFANILTEACSLQRGDRVMVILPKIPEWWL 129
Query 100 VILGAWRIGAVYQPLFTAFGPKAIEHRVQLAKSKLVVTDLGNRSKLDEVA-HCPPIMTVI 158
+ R G V P T K I +R+Q +KSK ++TD +D VA C + + +
Sbjct 130 ANVACLRTGTVLIPGTTQLTQKDILYRLQSSKSKCIITDDTLAPAVDIVAAKCENLHSKL 189
Query 159 GEKDHAVNDQDLNFWKQVSQASDHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKA--- 215
H+ N + + ASD V + + FTSGTTGP K + +
Sbjct 190 IVSQHSREGWG-NLKEMMKYASDSHTCVDTKHNELMAIYFTSGTTGPPKMIGHTHSSFGL 248
Query 216 -LIAFGHYMKDAIGLRTDDVFWNLADPGWAYGLYYAITGPLLLGHATL-FYEGGFSIDSL 273
L G + D I DV WN +D GWA + ++ P G Y F S+
Sbjct 249 GLSVNGRFWLDLIA---SDVMWNTSDTGWAKSAWSSVFSPWTQGACVFAHYLPRFDSTSI 305
Query 274 CQIIEDYKITNLAGAPTAYRMMMAADPAKIACLK-GKLRVISSAGEPLNPEVFRWFKHTL 332
Q + + IT APTAYRM++ D I K L+ SAGEP+NPEV +K
Sbjct 306 LQTLSKFPITVFCSAPTAYRMLIQND---ITSYKFNSLKHCVSAGEPINPEVMEQWKKKT 362
Query 333 DAPIFDHYGQTEVGMVVCNHHGLSHDVRAGTAGFASPGYRVAVVDEQGNELPADTAGILA 392
I++ YGQTE ++ N G+ ++ G+ G SP + V ++DE G LP G +A
Sbjct 363 GLDIYEGYGQTETVLICGNFKGMK--IKPGSMGKPSPAFNVEILDENGTILPPGQEGDIA 420
Query 393 VDIQKS-PMMWFGGYQESRK---SPFLKHYYLTGDTAELHADGSMSFVGRSDDVITTSGY 448
V + P F Y ++ S ++Y+TGD + DG FV RSDDVI +SGY
Sbjct 421 VQVLPDRPFGLFTHYVDNPSKTASTLRGNFYITGDRGYMDEDGYFWFVARSDDVILSSGY 480
Query 449 RIGPFDVESALIEHQAVIEAAVIGVPDPERTEIVKAFVILTA--QTSPSEQLAEELRQFV 506
RIGPF+VESALIEH ++ E+AV+ PDP R E+VKAF++L + EQL +E+++ V
Sbjct 481 RIGPFEVESALIEHPSIAESAVVSSPDPIRGEVVKAFIVLNPDYKLHDQEQLKKEIQEHV 540
Query 507 KKRLSAHAYPRQVEFVTELPKTPSGKIQRFLLRNQE 542
KK + + YPR++EF+ ELPKT SGK++R LR +E
Sbjct 541 KKTTAPYKYPRKIEFIEELPKTVSGKVKRNELRRKE 576
>Q8EDK3 Acetyl-coenzyme A synthetase [Shewanella oneidensis (strain
MR-1)]
Length=650
Score = 282 bits (722), Expect = 2e-90
Identities = 193/562 (34%), Positives = 287/562 (51%), Gaps = 34/562 (6%)
Query 9 TSFDFHRAA-NEMLSGSLDQVNACYECCDRHAESNPEKIALYWQGKDGR-QYQYTFAQLQ 66
T+FD H + N G+L NA C DRH ++ +++A+ W+G + Q + T+ +L
Sbjct 58 TTFDDHNLSINWFYDGTL---NASANCLDRHLAAHSDRVAIIWEGDNANEQRKITYGELH 114
Query 67 KWSSQFANFLKSQGVQTGDRISGLLPRTPELLVVILGAWRIGAVYQPLFTAFGPKAIEHR 126
+FAN L+SQGV+ GD ++ +P PE V +L RIGAV+ +F F P +I R
Sbjct 115 TQVCKFANALRSQGVRRGDIVTIYMPMVPEAAVAMLACARIGAVHSVVFGGFSPDSIASR 174
Query 127 VQLAKSKLVVT-DLGNRS--------KLDEVAHCPPIMTV--------IGEKDHAVNDQD 169
V KSK+V+T D G R +D+ P + +V G K V +D
Sbjct 175 VIDGKSKIVITSDEGMRGGRAIPLKRNIDDALKHPDVTSVEKVIVLKRTGGKIDWVEGRD 234
Query 170 LNFWKQVSQASDHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKALIAFGHYMKDAI-G 228
+ + V AS+HC + + P L++TSG+TG K + + + + +
Sbjct 235 VWWHSLVETASEHCAVEEMGAEDPLFLLYTSGSTGNPKGVLHTTGGYMVYASMTHEYVFD 294
Query 229 LRTDDVFWNLADPGWAYGLYYAITGPLLLGHATLFYEGGFSIDS---LCQIIEDYKITNL 285
+ +++W AD GW G Y + GPL G L +EG + S L ++I+ +K+ L
Sbjct 295 YKPGEIYWCTADVGWITGHSYMVYGPLANGATVLIHEGVPNHPSPARLGEMIDRHKVNIL 354
Query 286 AGAPTAYRMMMAADPAKIACLKGK-LRVISSAGEPLNPEVFRWFKHTLD---APIFDHYG 341
APT R +MA G LR++ S GEP+NPE +RW+ + PI D +
Sbjct 355 YTAPTLIRALMAEGKQHFDKYNGSSLRIMGSVGEPINPEAWRWYHEVIGHEHCPIVDTWW 414
Query 342 QTEVGMVVCNHHGLSHDVRAGTAGFASPGYRVAVVDEQGNELPADTAG-ILAVDIQKSPM 400
QTE G ++ + D + G+A G + A+VD GN L T G ++ +D M
Sbjct 415 QTETGGILITPLPGATDTKPGSATRPFFGVQPALVDNMGNILEGATEGNLVLLDSWPGQM 474
Query 401 MWFGGYQESRKSPFLKHY---YLTGDTAELHADGSMSFVGRSDDVITTSGYRIGPFDVES 457
G E + K + Y TGD A DG GR DDVI SG+R+G +VES
Sbjct 475 RTVYGDHERFVLTYFKTFRGMYFTGDGARRDEDGYYWITGRVDDVINVSGHRLGTAEVES 534
Query 458 ALIEHQAVIEAAVIGVPDPERTEIVKAFVILTAQTSPSEQLAEELRQFVKKRLSAHAYPR 517
AL+ H+ V EAAV+G P + + + A+V LT T SE+L +ELRQ+V+K + A A P
Sbjct 535 ALVSHELVAEAAVVGYPHDIKGQGIYAYVTLTRGTEESEELRQELRQWVRKEIGALATPD 594
Query 518 QVEFVTELPKTPSGKIQRFLLR 539
+++ T LPKT SGKI R LR
Sbjct 595 LIQWATGLPKTRSGKIMRRFLR 616
>Q0HTY6 Acetyl-coenzyme A synthetase [Shewanella sp. (strain MR-7)]
Length=650
Score = 282 bits (722), Expect = 2e-90
Identities = 194/562 (35%), Positives = 286/562 (51%), Gaps = 34/562 (6%)
Query 9 TSFDFHRAA-NEMLSGSLDQVNACYECCDRHAESNPEKIALYWQGKDG-RQYQYTFAQLQ 66
TSFD H + N G+L NA C DRH + +++A+ W+G + Q + T+ +L
Sbjct 58 TSFDDHNLSINWFYDGTL---NASANCLDRHLAEHSDRVAIIWEGDNASEQRKITYGELH 114
Query 67 KWSSQFANFLKSQGVQTGDRISGLLPRTPELLVVILGAWRIGAVYQPLFTAFGPKAIEHR 126
+FAN L+SQGV+ GD ++ +P PE V +L RIGAV+ +F F P +I R
Sbjct 115 TQVCKFANALRSQGVRRGDIVTIYMPMVPEAAVAMLACARIGAVHSVVFGGFSPDSIASR 174
Query 127 VQLAKSKLVVT-DLGNRS--------KLDEVAHCPPIMTV--------IGEKDHAVNDQD 169
V KSK+V+T D G R +D+ P + +V G K V +D
Sbjct 175 VIDGKSKVVITADEGMRGGRAIPLKRNIDDALKHPDVTSVEKVIVLKRTGGKVDWVEGRD 234
Query 170 LNFWKQVSQASDHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKALIAFGHYMKDAI-G 228
+ + V AS+HC + + P L++TSG+TG K + + + + +
Sbjct 235 VWWHSLVETASEHCAIEEMGAEDPLFLLYTSGSTGNPKGVLHTTGGYMVYASMTHEYVFD 294
Query 229 LRTDDVFWNLADPGWAYGLYYAITGPLLLGHATLFYEGGFSIDS---LCQIIEDYKITNL 285
+ +++W AD GW G Y + GPL G L +EG + S L ++I+ +K+ L
Sbjct 295 YKPGEIYWCTADVGWITGHSYMVYGPLANGATVLIHEGIPNHPSPARLGEMIDRHKVNIL 354
Query 286 AGAPTAYRMMMAADPAKIACLKGK-LRVISSAGEPLNPEVFRWFKHTLD---APIFDHYG 341
APT R +MA G LR++ S GEP+NPE +RW+ + PI D +
Sbjct 355 YTAPTLIRALMAEGKQHFDKYDGSSLRIMGSVGEPINPEAWRWYHEVIGHEHCPIVDTWW 414
Query 342 QTEVGMVVCNHHGLSHDVRAGTAGFASPGYRVAVVDEQGNELPADTAG-ILAVDIQKSPM 400
QTE G ++ + D + G+A G + A+VD GN L T G ++ +D M
Sbjct 415 QTETGGILITPLPGATDTKPGSATRPFFGVQPALVDNMGNILEGATEGNLVLLDSWPGQM 474
Query 401 MWFGGYQESRKSPFLKHY---YLTGDTAELHADGSMSFVGRSDDVITTSGYRIGPFDVES 457
G E + K + Y TGD A DG GR DDVI SG+R+G +VES
Sbjct 475 RTVYGDHERFVLTYFKTFRGMYFTGDGARRDEDGYYWITGRVDDVINVSGHRLGTAEVES 534
Query 458 ALIEHQAVIEAAVIGVPDPERTEIVKAFVILTAQTSPSEQLAEELRQFVKKRLSAHAYPR 517
AL+ H+ V EAAV+G P + + + A+V LT T SE+L +ELRQ+V+K + A A P
Sbjct 535 ALVSHELVAEAAVVGYPHDIKGQGIYAYVTLTRGTEESEELRQELRQWVRKEIGALATPD 594
Query 518 QVEFVTELPKTPSGKIQRFLLR 539
+++ T LPKT SGKI R LR
Sbjct 595 LIQWATGLPKTRSGKIMRRFLR 616
>Q0HHN4 Acetyl-coenzyme A synthetase [Shewanella sp. (strain MR-4)]
Length=650
Score = 281 bits (720), Expect = 4e-90
Identities = 193/562 (34%), Positives = 286/562 (51%), Gaps = 34/562 (6%)
Query 9 TSFDFHRAA-NEMLSGSLDQVNACYECCDRHAESNPEKIALYWQGKDG-RQYQYTFAQLQ 66
TSFD H + N G+L NA C DRH + +++A+ W+G + Q + T+ +L
Sbjct 58 TSFDDHNLSINWFYDGTL---NASANCLDRHLAEHSDRVAIIWEGDNASEQRKITYGELH 114
Query 67 KWSSQFANFLKSQGVQTGDRISGLLPRTPELLVVILGAWRIGAVYQPLFTAFGPKAIEHR 126
+FAN L+SQGV+ GD ++ +P PE V +L RIGAV+ +F F P +I R
Sbjct 115 TQVCKFANALRSQGVRRGDIVTIYMPMVPEAAVAMLACARIGAVHSVVFGGFSPDSIASR 174
Query 127 VQLAKSKLVVT-DLGNRS--------KLDEVAHCPPIMTV--------IGEKDHAVNDQD 169
V KSK+V+T D G R +D+ P + +V G K + +D
Sbjct 175 VIDGKSKVVITADEGMRGGRAIPLKRNIDDALKHPDVTSVEKVIVLKRTGGKVDWIEGRD 234
Query 170 LNFWKQVSQASDHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKALIAFGHYMKDAI-G 228
+ + V AS+HC + + P L++TSG+TG K + + + + +
Sbjct 235 VWWHSLVETASEHCAVEEMGAEDPLFLLYTSGSTGNPKGVLHTTGGYMVYASMTHEYVFD 294
Query 229 LRTDDVFWNLADPGWAYGLYYAITGPLLLGHATLFYEGGFSIDS---LCQIIEDYKITNL 285
+ +++W AD GW G Y + GPL G L +EG + S L ++I+ +K+ L
Sbjct 295 YKPGEIYWCTADVGWITGHSYMVYGPLANGATVLIHEGIPNHPSPARLGEMIDRHKVNIL 354
Query 286 AGAPTAYRMMMAADPAKIACLKGK-LRVISSAGEPLNPEVFRWFKHTLD---APIFDHYG 341
APT R +MA G LR++ S GEP+NPE +RW+ + PI D +
Sbjct 355 YTAPTLIRALMAEGKQHFDKYDGSSLRIMGSVGEPINPEAWRWYHEVIGHEHCPIVDTWW 414
Query 342 QTEVGMVVCNHHGLSHDVRAGTAGFASPGYRVAVVDEQGNELPADTAG-ILAVDIQKSPM 400
QTE G ++ + D + G+A G + A+VD GN L T G ++ +D M
Sbjct 415 QTETGGILITPLPGATDTKPGSATRPFFGVQPALVDNMGNILEGATEGNLVLLDSWPGQM 474
Query 401 MWFGGYQESRKSPFLKHY---YLTGDTAELHADGSMSFVGRSDDVITTSGYRIGPFDVES 457
G E + K + Y TGD A DG GR DDVI SG+R+G +VES
Sbjct 475 RTVYGDHERFVLTYFKTFRGMYFTGDGARRDEDGYYWITGRVDDVINVSGHRLGTAEVES 534
Query 458 ALIEHQAVIEAAVIGVPDPERTEIVKAFVILTAQTSPSEQLAEELRQFVKKRLSAHAYPR 517
AL+ H+ V EAAV+G P + + + A+V LT T SE+L +ELRQ+V+K + A A P
Sbjct 535 ALVSHELVAEAAVVGYPHDIKGQGIYAYVTLTRGTEESEELRQELRQWVRKEIGALATPD 594
Query 518 QVEFVTELPKTPSGKIQRFLLR 539
+++ T LPKT SGKI R LR
Sbjct 595 LIQWATGLPKTRSGKIMRRFLR 616
>Q3UNX5 Acyl-coenzyme A synthetase ACSM3, mitochondrial [Mus musculus]
Length=580
Score = 277 bits (708), Expect = 4e-89
Identities = 182/515 (35%), Positives = 273/515 (53%), Gaps = 24/515 (5%)
Query 41 SNPEKIALYWQGKDGRQYQYTFAQLQKWSSQFANFL-KSQGVQTGDRISGLLPRTPELLV 99
SNP A +W +G + +++F +L S +FAN L ++ +Q GDR+ +LP+ PE +
Sbjct 73 SNP---AFWWIDGNGEELRWSFEELGLLSRKFANILTEACSLQRGDRVMVILPKIPEWWL 129
Query 100 VILGAWRIGAVYQPLFTAFGPKAIEHRVQLAKSKLVVTDLGNRSKLDEVA-HCPPIMTVI 158
+ R G V P T K I +R+Q +K+K ++TD +D VA C + + +
Sbjct 130 ANVACLRTGTVLIPGTTQLTQKDILYRLQSSKAKCIITDDTLAPAVDAVAAKCENLHSKL 189
Query 159 GEKDHAVNDQDLNFWKQVSQASDHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKA--- 215
H+ N + + ASD V + + FTSGTTGP K + +
Sbjct 190 IVSQHSREGWG-NLKEMMKYASDSHTCVDTKHDEMMAIYFTSGTTGPPKMIGHTHSSFGL 248
Query 216 -LIAFGHYMKDAIGLRTDDVFWNLADPGWAYGLYYAITGPLLLGHATL-FYEGGFSIDSL 273
L G + D I DV WN +D GWA + ++ P G Y F S+
Sbjct 249 GLSVNGRFWLDLIA---SDVMWNTSDTGWAKSAWSSVFSPWTQGACVFAHYLPRFESTSI 305
Query 274 CQIIEDYKITNLAGAPTAYRMMMAADPAKIACLKGKLRVISSAGEPLNPEVFRWFKHTLD 333
Q + + IT APTAYRM++ D + L+ SAGEP+NPEV ++
Sbjct 306 LQTLSKFPITVFCSAPTAYRMLVQNDMSSYKF--NSLKHCVSAGEPINPEVMEQWRKKTG 363
Query 334 APIFDHYGQTEVGMVVCNHHGLSHDVRAGTAGFASPGYRVAVVDEQGNELPADTAGILAV 393
I++ YGQTE ++ N G+ ++ G+ G SP + V ++DE G LP G +A+
Sbjct 364 LDIYEGYGQTETVLICGNFKGMK--IKPGSMGKPSPAFDVKILDENGATLPPGQEGDIAL 421
Query 394 DI-QKSPMMWFGGYQESRK---SPFLKHYYLTGDTAELHADGSMSFVGRSDDVITTSGYR 449
+ + P F Y ++ S +Y+TGD + DG FV RSDD+I +SGYR
Sbjct 422 QVLPERPFGLFTHYVDNPSKTASTLRGSFYITGDRGYMDEDGYFWFVARSDDIILSSGYR 481
Query 450 IGPFDVESALIEHQAVIEAAVIGVPDPERTEIVKAFVILTA--QTSPSEQLAEELRQFVK 507
IGPF+VESALIEH ++ E+AV+ PDP R E+VKAF++L ++ EQL +E+++ VK
Sbjct 482 IGPFEVESALIEHPSIAESAVVSSPDPIRGEVVKAFIVLNPDYKSHDQEQLKKEIQEHVK 541
Query 508 KRLSAHAYPRQVEFVTELPKTPSGKIQRFLLRNQE 542
K + + YPR+VEF+ ELPKT SGK++R LR +E
Sbjct 542 KTTAPYKYPRKVEFIEELPKTVSGKVKRNELRKKE 576
>Q08AH1 Acyl-coenzyme A synthetase ACSM1, mitochondrial [Homo
sapiens]
Length=577
Score = 272 bits (696), Expect = 2e-87
Identities = 177/518 (34%), Positives = 275/518 (53%), Gaps = 39/518 (8%)
Query 47 ALYWQGKDGRQYQYTFAQLQKWSSQFAN-FLKSQGVQTGDRISGLLPRTPELLVVILGAW 105
A +W G + +++F ++ + + AN F ++ G+Q GD ++ +LPR PE +V +G
Sbjct 73 AFWWVNGQGDEVKWSFREMGDLTRRVANVFTQTCGLQQGDHLALMLPRVPEWWLVAVGCM 132
Query 106 RIGAVYQPLFTAFGPKAIEHRVQLAKSKLVVTDLGNRSKLDEVA-HCPPIMTVIGEKDHA 164
R G ++ P K I +R+QL+K+K +VT S++D +A CP + T + DH+
Sbjct 133 RTGIIFIPATILLKAKDILYRLQLSKAKGIVTIDALASEVDSIASQCPSLKTKLLVSDHS 192
Query 165 VNDQDLNFWKQVSQASDHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKALIAFGHYMK 224
+ L+F V AS V P ++ FTSGTTG P A + G ++
Sbjct 193 -REGWLDFRSLVKSASPEHTCVKSKTLDPMVIFFTSGTTG------FPKMAKHSHGLALQ 245
Query 225 DAI-------GLRTDDVFWNLADPGWAYGLYYAITGPLLLGHATLFYE-GGFSIDSLCQI 276
+ L+T DV W L+D GW + + P G + F + Q
Sbjct 246 PSFPGSRKLRSLKTSDVSWCLSDSGWIVATIWTLVEPWTAGCTVFIHHLPQFDTKVIIQT 305
Query 277 IEDYKITNLAGAPTAYRMMMAAD------PAKIACLKGKLRVISSAGEPLNPEVFRWFKH 330
+ Y I + G + YRM++ D PA C G GE + P+ +K
Sbjct 306 LLKYPINHFWGVSSIYRMILQQDFTSIRFPALEHCYTG--------GEVVLPKDQEEWKR 357
Query 331 TLDAPIFDHYGQTEVGMVVCNHHGLSHDVRAGTAGFASPGYRVAVVDEQGNELPADTAGI 390
++++YGQ+E G++ + G+ ++ G G A+P Y V V+D++G+ LP +T G
Sbjct 358 RTGLLLYENYGQSETGLICATYWGMK--IKPGFMGKATPPYDVQVIDDKGSILPPNTEGN 415
Query 391 LAVDIQK----SPMMWFGGYQESRKSPFLKHYYLTGDTAELHADGSMSFVGRSDDVITTS 446
+ + I+ S M + G E +Y TGD ++ +G + F+GRSDD+I S
Sbjct 416 IGIRIKPVRPVSLFMCYEGDPEKTAKVECGDFYNTGDRGKMDEEGYICFLGRSDDIINAS 475
Query 447 GYRIGPFDVESALIEHQAVIEAAVIGVPDPERTEIVKAFVILTAQ--TSPSEQLAEELRQ 504
GYRIGP +VESAL+EH AV E+AV+G PDP R E+VKAF++LT Q + +QL +EL+Q
Sbjct 476 GYRIGPAEVESALVEHPAVAESAVVGSPDPIRGEVVKAFIVLTPQFLSHDKDQLTKELQQ 535
Query 505 FVKKRLSAHAYPRQVEFVTELPKTPSGKIQRFLLRNQE 542
VK + + YPR+VEFV+ELPKT +GKI+R LR +E
Sbjct 536 HVKSVTAPYKYPRKVEFVSELPKTITGKIERKELRKKE 573
>Q68CK6 Acyl-coenzyme A synthetase ACSM2B, mitochondrial [Homo
sapiens]
Length=577
Score = 267 bits (683), Expect = 2e-85
Identities = 182/513 (35%), Positives = 267/513 (52%), Gaps = 30/513 (6%)
Query 47 ALYWQGKDGRQYQYTFAQLQKWSSQFANFLKSQ-GVQTGDRISGLLPRTPELLVVILGAW 105
AL+W G++ + F +L + S Q AN L G+Q GDR++ +LPR PE +VILG
Sbjct 68 ALWWVNGKGKELMWNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCI 127
Query 106 RIGAVYQPLFTAFGPKAIEHRVQLAKSKLVVTDLGNRSKLDEVA-HCPP--IMTVIGEKD 162
R G ++ P I +R+Q++K+K +V ++D VA CP I ++ EK
Sbjct 128 RAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKS 187
Query 163 HAVNDQDLNFWKQVSQASDHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKALIAFGHY 222
D LNF K +++AS V Q+ + FTSGT+G K E +L
Sbjct 188 C---DGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKM 244
Query 223 MKDAIGLRTDDVFWNLADPGWAYGLYYAITGPLLLGHATLFYE-GGFSIDSLCQIIEDYK 281
GL+ D+ W ++D GW + ++ LG T + F + + + Y
Sbjct 245 DAGWTGLQASDIMWTISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYP 304
Query 282 ITNLAGAPTAYRMMMAAD------PAKIACLKGKLRVISSAGEPLNPEVFRWFKHTLDAP 335
I ++ GAP YRM++ D P CL G GE L PE ++
Sbjct 305 IKSMMGAPIVYRMLLQQDLSSYKFPHLQNCLAG--------GESLLPETLENWRAQTGLD 356
Query 336 IFDHYGQTEVGMVVCNHHGLSHDVRAGTAGFASPGYRVAVVDEQGNELPADTAGILAVDI 395
I + YGQTE G+ + ++ G G A+ Y V V+D++GN LP T G + + +
Sbjct 357 IREFYGQTETGLTCMVSKTMK--IKPGYMGTAASCYDVQVIDDKGNVLPPGTEGDIGIRV 414
Query 396 QK-SPMMWFGGYQESRKSPFLK---HYYLTGDTAELHADGSMSFVGRSDDVITTSGYRIG 451
+ P+ F GY E+ ++L GD DG F+GR+DD+I +SGYRIG
Sbjct 415 KPIRPIGIFSGYVENPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRADDIINSSGYRIG 474
Query 452 PFDVESALIEHQAVIEAAVIGVPDPERTEIVKAFVILTAQ--TSPSEQLAEELRQFVKKR 509
P +VE+AL++H AV+E AVI PDP R E+VKAFVIL +Q + EQL +EL+Q VK
Sbjct 475 PSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKELQQHVKSV 534
Query 510 LSAHAYPRQVEFVTELPKTPSGKIQRFLLRNQE 542
+ + YPR++EFV LPKT +GKIQR LR++E
Sbjct 535 TAPYKYPRKIEFVLNLPKTVTGKIQRTKLRDKE 567
>Q08AH3 Acyl-coenzyme A synthetase ACSM2A, mitochondrial [Homo
sapiens]
Length=577
Score = 267 bits (682), Expect = 3e-85
Identities = 177/507 (35%), Positives = 268/507 (53%), Gaps = 18/507 (4%)
Query 47 ALYWQGKDGRQYQYTFAQLQKWSSQFANFLKSQ-GVQTGDRISGLLPRTPELLVVILGAW 105
AL+W G++ + F +L + S Q AN L G+Q GDR++ +LPR PE +VILG
Sbjct 68 ALWWVNGKGKELMWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCI 127
Query 106 RIGAVYQPLFTAFGPKAIEHRVQLAKSKLVVTDLGNRSKLDEVA-HCPP--IMTVIGEKD 162
R G ++ P I +R+Q++K+K +V ++D VA CP I ++ EK
Sbjct 128 RAGLIFMPGTIQMKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLVSEKS 187
Query 163 HAVNDQDLNFWKQVSQASDHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKALIAFGHY 222
D LNF K +++AS V Q+ + FTSGT+G K E +L
Sbjct 188 C---DGWLNFKKLLNEASTTHHCVETGSQEASAIYFTSGTSGLPKMAEHSYSSLGLKAKM 244
Query 223 MKDAIGLRTDDVFWNLADPGWAYGLYYAITGPLLLGHATLFYE-GGFSIDSLCQIIEDYK 281
GL+ D+ W ++D GW + ++ P LG T + F + + + Y
Sbjct 245 DAGWTGLQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYP 304
Query 282 ITNLAGAPTAYRMMMAADPAKIACLKGKLRVISSAGEPLNPEVFRWFKHTLDAPIFDHYG 341
I ++ GAP YRM++ D + L+ + GE L PE ++ I + YG
Sbjct 305 IKSMMGAPIVYRMLLQQDLSSYKF--PHLQNCVTVGESLLPETLENWRAQTGLDIRESYG 362
Query 342 QTEVGMVVCNHHGLSHDVRAGTAGFASPGYRVAVVDEQGNELPADTAGILAVDIQK-SPM 400
QTE G+ + ++ G G A+ Y V ++D++GN LP T G + + ++ P+
Sbjct 363 QTETGLTCMVSKTMK--IKPGYMGTAASCYDVQIIDDKGNVLPPGTEGDIGIRVKPIRPI 420
Query 401 MWFGGYQESRKSPFLK---HYYLTGDTAELHADGSMSFVGRSDDVITTSGYRIGPFDVES 457
F GY ++ ++L GD DG F+GR++D+I +SGYRIGP +VE+
Sbjct 421 GIFSGYVDNPDKTAANIRGDFWLLGDRGIKDEDGYFQFMGRANDIINSSGYRIGPSEVEN 480
Query 458 ALIEHQAVIEAAVIGVPDPERTEIVKAFVILTAQ--TSPSEQLAEELRQFVKKRLSAHAY 515
AL+EH AV+E AVI PDP R E+VKAFV+L +Q + EQL +EL+Q VK + + Y
Sbjct 481 ALMEHPAVVETAVISSPDPVRGEVVKAFVVLASQFLSHDPEQLTKELQQHVKSVTAPYKY 540
Query 516 PRQVEFVTELPKTPSGKIQRFLLRNQE 542
PR++EFV LPKT +GKIQR LR++E
Sbjct 541 PRKIEFVLNLPKTVTGKIQRAKLRDKE 567
>Q91VA0 Acyl-coenzyme A synthetase ACSM1, mitochondrial [Mus musculus]
Length=573
Score = 265 bits (677), Expect = 1e-84
Identities = 168/511 (33%), Positives = 275/511 (54%), Gaps = 19/511 (4%)
Query 47 ALYWQGKDGRQYQYTFAQLQKWSSQFAN-FLKSQGVQTGDRISGLLPRTPELLVVILGAW 105
A +W G + +++F +L+ + + AN F + G+Q GD ++ +LPR PE +V +G
Sbjct 69 AFWWVNGQGDEIKWSFRKLRDLTCRTANVFEQICGLQQGDHLALILPRVPEWWLVTVGCM 128
Query 106 RIGAVYQPLFTAFGPKAIEHRVQLAKSKLVVTDLGNRSKLDEVA-HCPPIMTVIGEKDHA 164
R G ++ P T K I +R+Q++++K +VT +++ VA CP + T + DH+
Sbjct 129 RTGIIFMPGTTQLKAKDILYRIQISRAKAIVTTASLVPEVESVASECPDLKTKLVVSDHS 188
Query 165 VNDQDLNFWKQVSQASDHCDLVLQDIQKPFLLMFTSGTTGPAKPLEVPLKALIAFGHYM- 223
++ L+F + AS + ++ P + FTSGTTG P +AF Y+
Sbjct 189 -HEGWLDFCSLIKSASPDHTCIKSKMKDPMAIFFTSGTTG--YPKMAKHNQGLAFRSYIP 245
Query 224 --KDAIGLRTDDVFWNLADPGWAYGLYYAITGPLLLGHATLFYE-GGFSIDSLCQIIEDY 280
+ + L+T D+ W ++DPGW + P G + F + +++ Y
Sbjct 246 SCRKLLKLKTSDILWCMSDPGWILATVGCLIEPWTSGCTVFIHHLPQFDPKVIVEVLFKY 305
Query 281 KITNLAGAPTAYRMMMAADPAKIACLKGKLRVISSAGEPLNPEVFRWFKHTLDAPIFDHY 340
IT AP YRM++ + + L ++ GE L PE + +K I + Y
Sbjct 306 PITQCLAAPGVYRMVLQQKTSNLRF--PTLEHCTTGGESLLPEEYEQWKQRTGLSIHEVY 363
Query 341 GQTEVGMVVCNHHGLSHDVRAGTAGFASPGYRVAVVDEQGNELPADTAGILAVDIQKS-P 399
GQ+E G+ + ++ G+ G A + + ++DE+GN LP +T G + + I+ + P
Sbjct 364 GQSETGISSATLREMK--IKRGSIGKAILPFDLQIIDEKGNILPPNTEGYIGIRIKPTRP 421
Query 400 MMWFGGYQESRKSPF---LKHYYLTGDTAELHADGSMSFVGRSDDVITTSGYRIGPFDVE 456
+ F Y+ S +S +Y +GD A + +G + F+GR DDVI SGYRIGP +VE
Sbjct 422 LGLFMEYENSPESTSEVECGDFYNSGDRATIDEEGYIWFLGRGDDVINASGYRIGPVEVE 481
Query 457 SALIEHQAVIEAAVIGVPDPERTEIVKAFVILTAQ--TSPSEQLAEELRQFVKKRLSAHA 514
+AL EH AV E+AV+ PD +R E+VKAF++L + + EQL +EL+ VK + +
Sbjct 482 NALAEHPAVAESAVVSSPDKDRGEVVKAFIVLNPEFLSHDQEQLIKELQHHVKSVTAPYK 541
Query 515 YPRQVEFVTELPKTPSGKIQRFLLRNQEIAK 545
YPR+VEFV+ELPKT +GKI+R LRN+E +
Sbjct 542 YPRKVEFVSELPKTVTGKIKRKELRNKEFGQ 572
Lambda K H a alpha
0.321 0.137 0.417 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 4008090
Database: b19074d01be514d6b0dfa95864f7f941.SwissProt.fasta
Posted date: Jun 3, 2024 8:09 AM
Number of letters in database: 8,955
Number of sequences in database: 15
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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