BLASTP 2.12.0+
Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.
Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.
Database: 11b82e4029df2374cf7b992a9706e62e.SwissProt.fasta
24 sequences; 24,246 total letters
Query= ACIAD2876
Length=947
Score E
Sequences producing significant alignments: (Bits) Value
P20707 2-oxoglutarate dehydrogenase E1 component [Azotobacter vin... 1226 0.0
P0AFG4 2-oxoglutarate dehydrogenase E1 component [Escherichia col... 1074 0.0
P0AFG5 2-oxoglutarate dehydrogenase E1 component [Escherichia col... 1074 0.0
P0AFG3 2-oxoglutarate dehydrogenase E1 component [Escherichia col... 1074 0.0
Q59106 2-oxoglutarate dehydrogenase E1 component [Cupriavidus nec... 1030 0.0
P45303 2-oxoglutarate dehydrogenase E1 component [Haemophilus inf... 1008 0.0
P51056 2-oxoglutarate dehydrogenase E1 component [Coxiella burnet... 922 0.0
P57388 2-oxoglutarate dehydrogenase E1 component [Buchnera aphidi... 825 0.0
Q8FYF7 2-oxoglutarate dehydrogenase E1 component [Brucella suis b... 803 0.0
B0CIS7 2-oxoglutarate dehydrogenase E1 component [Brucella suis (... 803 0.0
A9M8Q9 2-oxoglutarate dehydrogenase E1 component [Brucella canis ... 803 0.0
A6WXF0 2-oxoglutarate dehydrogenase E1 component [Brucella anthro... 802 0.0
A5VSQ0 2-oxoglutarate dehydrogenase E1 component [Brucella ovis (... 801 0.0
Q8YJE4 2-oxoglutarate dehydrogenase E1 component [Brucella melite... 800 0.0
C0RFG8 2-oxoglutarate dehydrogenase E1 component [Brucella melite... 800 0.0
Q57AX5 2-oxoglutarate dehydrogenase E1 component [Brucella abortu... 800 0.0
Q2YLS2 2-oxoglutarate dehydrogenase E1 component [Brucella abortu... 800 0.0
B2S877 2-oxoglutarate dehydrogenase E1 component [Brucella abortu... 800 0.0
A0R2B1 2-oxoglutarate dehydrogenase E1 component / Dihydrolipoyll... 723 0.0
P9WIS5 2-oxoglutarate dehydrogenase E1 component / Dihydrolipoyll... 706 0.0
Q8NRC3 2-oxoglutarate dehydrogenase E1 component / Dihydrolipoyll... 697 0.0
P20967 2-oxoglutarate dehydrogenase, mitochondrial [Saccharomyces... 692 0.0
Q02218 2-oxoglutarate dehydrogenase complex component E1 [Homo sa... 677 0.0
Q5XI78 2-oxoglutarate dehydrogenase complex component E1 [Rattus ... 677 0.0
>P20707 2-oxoglutarate dehydrogenase E1 component [Azotobacter
vinelandii]
Length=943
Score = 1226 bits (3171), Expect = 0.0
Identities = 598/943 (63%), Positives = 732/943 (78%), Gaps = 6/943 (1%)
Query 1 MQD-VADALRLDTELSADSAAYIEELYEQYLTSPTSVTEDWRQYFDKFP-----KGDQPH 54
MQD V + LS +AAY+EELYE YL P +V E+WR YF+K P D PH
Sbjct 1 MQDSVMQRMWNSAHLSGGNAAYVEELYELYLHDPNAVPEEWRTYFEKLPAEAGTSTDVPH 60
Query 55 SSVREQFLLLGRNSNRVQAVVQSSVSSDHERRQIGVLQLIAAYRNRGHQKAKLDPLGLAK 114
+ VR+QF+LL +N R Q V SSVS++HE++Q+ VL+LI AYR RGHQ ++LDPLGL +
Sbjct 61 APVRDQFVLLAKNQRRAQPVATSSVSTEHEKKQVEVLRLIQAYRTRGHQASQLDPLGLWQ 120
Query 115 REDVPDLDLSAHGLTKSDLDTVFNTSNLAIGKAEATLGEMVETMESIYCGSIGAEYMHIV 174
R DL ++ +GLT +DLDT F T L IGK EATL E+++ ++ YC +IGAE+ HIV
Sbjct 121 RTAPSDLSITHYGLTNADLDTPFRTGELYIGKEEATLREILQALQETYCRTIGAEFTHIV 180
Query 175 DTKEKRWIQQRLEGARGQFNFTNDQKKALLERLTAAEGLEKFLGNKYVGAKRFGVEGGES 234
D++++ W QRLE RG+ ++ + K LLERL+AAEGLEK+LG KY G KRFG+EGGES
Sbjct 181 DSEQRNWFAQRLESVRGRPVYSKEAKSHLLERLSAAEGLEKYLGTKYPGTKRFGLEGGES 240
Query 235 FIPMMNEIIQRAGSVGCKEVVIGMPHRGRLNLLVNIMGKNPADLFGEFEGKSIHKKGSGD 294
+P+++EIIQR+GS G KEVVIGM HRGRLNLLVN +GKNP DLF EFEGK + + GSGD
Sbjct 241 LVPVVDEIIQRSGSYGTKEVVIGMAHRGRLNLLVNALGKNPRDLFDEFEGKHLVELGSGD 300
Query 295 VKYHQGFSSNVMTPGGEVHLALAFNPSHLEIVGPVVEGSVRARQVRRKDIGGDDVLPVIV 354
VKYHQGFSSNVMT GGEVHLA+AFNPSHLEIV PVVEGSVRARQ RR D G+ V+P+ +
Sbjct 301 VKYHQGFSSNVMTSGGEVHLAMAFNPSHLEIVSPVVEGSVRARQDRRVDATGEKVVPISI 360
Query 355 HGDAAFAGQGVNQETFQMSQTRGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKM 414
HGD+AFAGQGV ETFQMSQ RGY GGT+HIV+NNQVGFTTS+P D RSTEYCTD AKM
Sbjct 361 HGDSAFAGQGVVMETFQMSQIRGYKTGGTIHIVVNNQVGFTTSNPVDTRSTEYCTDPAKM 420
Query 415 VQSPIFHVNGDDPEAVAFIAQLAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMY 474
+Q+P+ HVNGDDPEAV F+ QLA D+R F++DVVIDL CYRRRGHNEADEPS TQPLMY
Sbjct 421 IQAPVLHVNGDDPEAVLFVTQLAVDYRMQFKRDVVIDLVCYRRRGHNEADEPSGTQPLMY 480
Query 475 QVINKKPTTRTLYADQLVQQKVLDRAEADKLIEDYRSDLEAGNHVANALVLEPNTKMFVD 534
Q I K+PTTR LYAD LV++ L + E +++YR+ L+ G HV +LV EPNT++FVD
Sbjct 481 QKIAKQPTTRELYADALVKEGSLSQEEVQAKVDEYRTALDNGQHVLKSLVKEPNTELFVD 540
Query 535 WKPYLGHDYTDVWDTTIDINRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKMQTGEMPLN 594
W PYLGH +T DT+ ++ L+EL + ++PEGFV+QRQV+K+++DR +M G MP+N
Sbjct 541 WTPYLGHAWTARHDTSFELKTLQELNAKLLQIPEGFVVQRQVAKILEDRGRMGVGAMPIN 600
Query 595 WGAAETLAYATLIDEGYLVRITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQPRF 654
WG AETLAYATL+ EG+ VRITG+DVGRGTFSHRHA LHNQ D S YIPL ++ E QP+F
Sbjct 601 WGCAETLAYATLLKEGHPVRITGQDVGRGTFSHRHAALHNQKDASRYIPLQNLYEGQPKF 660
Query 655 ALYDSLLSEEAVLAFEYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVC 714
LYDS LSEEAVLAFEYGYATT PN+L+IWEA GDFAN AQVVIDQFI+SGETKW +C
Sbjct 661 ELYDSFLSEEAVLAFEYGYATTTPNALVIWEASSGDFANGAQVVIDQFISSGETKWGALC 720
Query 715 GLTMLLPHGFEGQGPEHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKP 774
GLTMLLPHG+EGQGPEHSSARLER+LQLCAE N+QV PTTPAQ++H LRRQ +RP+RKP
Sbjct 721 GLTMLLPHGYEGQGPEHSSARLERYLQLCAEQNIQVCVPTTPAQVYHMLRRQVIRPLRKP 780
Query 775 MIVMSPKSLLRHKLATSTLEELATGTFQTVIDEVDQITKSDVTRLVLCGGKVYYDLIEKR 834
++ ++PKSLLRHK A STLE+LA G+F V+ EVD + V RLVLC GKVYYDL++KR
Sbjct 781 LVALTPKSLLRHKSAISTLEDLALGSFHPVLPEVDSLDPKKVERLVLCSGKVYYDLLDKR 840
Query 835 RELELNNIAVVRIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDD 894
+IA+VRIEQLYP+PE+ LAEV+A Y N+K VVWCQEEP NQGAW +
Sbjct 841 HAEGREDIAIVRIEQLYPFPEEELAEVMAPYTNLKHVVWCQEEPMNQGAWYCSQHHMRRV 900
Query 895 ILKSGKQIRISYAGREASAAPACGSPYLHAKQQAQLIHDALAI 937
K++ + YAGREASAAPACG +HA+QQ +L+ DA +
Sbjct 901 ASAHKKELFLQYAGREASAAPACGYASMHAEQQEKLLQDAFTV 943
>P0AFG4 2-oxoglutarate dehydrogenase E1 component [Escherichia
coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)]
Length=933
Score = 1074 bits (2778), Expect = 0.0
Identities = 543/943 (58%), Positives = 681/943 (72%), Gaps = 15/943 (2%)
Query 1 MQDVADALRLDTE-LSADSAAYIEELYEQYLTSPTSVTEDWRQYFDKFP----KGDQPHS 55
MQ+ A LD+ LS + ++IE+LYE +LT P SV +WR F + P K DQ HS
Sbjct 1 MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRSTFQQLPGTGVKPDQFHS 60
Query 56 SVREQFLLLGRNSNRVQAVVQSSVSSDHERRQIGVLQLIAAYRNRGHQKAKLDPLGLAKR 115
RE F L ++++R + + D +Q+ VLQLI AYR RGHQ A LDPLGL ++
Sbjct 61 QTREYFRRLAKDASRYSSTISDP---DTNVKQVKVLQLINAYRFRGHQHANLDPLGLWQQ 117
Query 116 EDVPDLDLSAHGLTKSDLDTVFNTSNLAIGKAEATLGEMVETMESIYCGSIGAEYMHIVD 175
+ V DLD S H LT++D FN + A GK LGE++E ++ YCG IGAEYMHI
Sbjct 118 DKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEALKQTYCGPIGAEYMHITS 177
Query 176 TKEKRWIQQRLEGARGQFNFTNDQKKALLERLTAAEGLEKFLGNKYVGAKRFGVEGGESF 235
T+EKRWIQQR+E R FN +++KK L LTAAEGLE++LG K+ GAKRF +EGG++
Sbjct 178 TEEKRWIQQRIESGRATFN--SEEKKRFLSELTAAEGLERYLGAKFPGAKRFSLEGGDAL 235
Query 236 IPMMNEIIQRAGSVGCKEVVIGMPHRGRLNLLVNIMGKNPADLFGEFEGKSIHKKGSGDV 295
IPM+ E+I+ AG+ G +EVV+GM HRGRLN+LVN++GK P DLF EF GK G+GDV
Sbjct 236 IPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTGDV 295
Query 296 KYHQGFSSNVMTPGGEVHLALAFNPSHLEIVGPVVEGSVRARQVRRKDIGGDDVLPVIVH 355
KYH GFSS+ T GG VHLALAFNPSHLEIV PVV GSVRAR R + + VLP+ +H
Sbjct 296 KYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPITIH 355
Query 356 GDAAFAGQGVNQETFQMSQTRGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMV 415
GDAA GQGV QET MS+ RGY VGGTV IVINNQVGFTTS+P DARST YCTD+ KMV
Sbjct 356 GDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYCTDIGKMV 415
Query 416 QSPIFHVNGDDPEAVAFIAQLAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQ 475
Q+PIFHVN DDPEAVAF+ +LA DFR+TF++DV IDL CYRR GHNEADEPSATQPLMYQ
Sbjct 416 QAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQPLMYQ 475
Query 476 VINKKPTTRTLYADQLVQQKVLDRAEADKLIEDYRSDLEAGNHVANALVLEPNTKMFVDW 535
I K PT R +YAD+L Q+KV +A +++ YR L+AG+ V P W
Sbjct 476 KIKKHPTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEW--RPMNMHSFTW 533
Query 536 KPYLGHDYTDVWDTTIDINRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKMQTGEMPLNW 595
PYL H++ + + +++ RL+EL + + +PE MQ +V+K+ DR M GE +W
Sbjct 534 SPYLNHEWDEEYPNKVEMKRLQELAKRISTVPEAVEMQSRVAKIYGDRQAMAAGEKLFDW 593
Query 596 GAAETLAYATLIDEGYLVRITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQPRFA 655
G AE LAYATL+DEG VR++GED GRGTF HRHA +HNQ +GSTY PL H+ Q F
Sbjct 594 GGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTYTPLQHIHNGQGAFR 653
Query 656 LYDSLLSEEAVLAFEYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCG 715
++DS+LSEEAVLAFEYGYAT P +L IWEAQFGDFAN AQVVIDQFI+SGE KW R+CG
Sbjct 654 VWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFISSGEQKWGRMCG 713
Query 716 LTMLLPHGFEGQGPEHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPM 775
L MLLPHG+EGQGPEHSSARLER+LQLCAE NMQV P+TPAQ++H LRRQA+R +R+P+
Sbjct 714 LVMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPL 773
Query 776 IVMSPKSLLRHKLATSTLEELATGTFQTVIDEVDQITKSDVTRLVLCGGKVYYDLIEKRR 835
+VMSPKSLLRH LA S+LEELA GTF I E+D++ V R+V+C GKVYYDL+E+RR
Sbjct 774 VVMSPKSLLRHPLAVSSLEELANGTFLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRR 833
Query 836 ELELNNIAVVRIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDI 895
+ +++A+VRIEQLYP+P + + EVL + +VKD VWCQEEP NQGAW + + + ++
Sbjct 834 KNNQHDVAIVRIEQLYPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQGAW-YCSQHHFREV 892
Query 896 LKSGKQIRISYAGREASAAPACGSPYLHAKQQAQLIHDALAIE 938
+ G +R YAGR ASA+PA G +H KQQ L++DAL +E
Sbjct 893 IPFGASLR--YAGRPASASPAVGYMSVHQKQQQDLVNDALNVE 933
>P0AFG5 2-oxoglutarate dehydrogenase E1 component [Escherichia
coli O157:H7]
Length=933
Score = 1074 bits (2778), Expect = 0.0
Identities = 543/943 (58%), Positives = 681/943 (72%), Gaps = 15/943 (2%)
Query 1 MQDVADALRLDTE-LSADSAAYIEELYEQYLTSPTSVTEDWRQYFDKFP----KGDQPHS 55
MQ+ A LD+ LS + ++IE+LYE +LT P SV +WR F + P K DQ HS
Sbjct 1 MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRSTFQQLPGTGVKPDQFHS 60
Query 56 SVREQFLLLGRNSNRVQAVVQSSVSSDHERRQIGVLQLIAAYRNRGHQKAKLDPLGLAKR 115
RE F L ++++R + + D +Q+ VLQLI AYR RGHQ A LDPLGL ++
Sbjct 61 QTREYFRRLAKDASRYSSTISDP---DTNVKQVKVLQLINAYRFRGHQHANLDPLGLWQQ 117
Query 116 EDVPDLDLSAHGLTKSDLDTVFNTSNLAIGKAEATLGEMVETMESIYCGSIGAEYMHIVD 175
+ V DLD S H LT++D FN + A GK LGE++E ++ YCG IGAEYMHI
Sbjct 118 DKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEALKQTYCGPIGAEYMHITS 177
Query 176 TKEKRWIQQRLEGARGQFNFTNDQKKALLERLTAAEGLEKFLGNKYVGAKRFGVEGGESF 235
T+EKRWIQQR+E R FN +++KK L LTAAEGLE++LG K+ GAKRF +EGG++
Sbjct 178 TEEKRWIQQRIESGRATFN--SEEKKRFLSELTAAEGLERYLGAKFPGAKRFSLEGGDAL 235
Query 236 IPMMNEIIQRAGSVGCKEVVIGMPHRGRLNLLVNIMGKNPADLFGEFEGKSIHKKGSGDV 295
IPM+ E+I+ AG+ G +EVV+GM HRGRLN+LVN++GK P DLF EF GK G+GDV
Sbjct 236 IPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTGDV 295
Query 296 KYHQGFSSNVMTPGGEVHLALAFNPSHLEIVGPVVEGSVRARQVRRKDIGGDDVLPVIVH 355
KYH GFSS+ T GG VHLALAFNPSHLEIV PVV GSVRAR R + + VLP+ +H
Sbjct 296 KYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPITIH 355
Query 356 GDAAFAGQGVNQETFQMSQTRGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMV 415
GDAA GQGV QET MS+ RGY VGGTV IVINNQVGFTTS+P DARST YCTD+ KMV
Sbjct 356 GDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYCTDIGKMV 415
Query 416 QSPIFHVNGDDPEAVAFIAQLAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQ 475
Q+PIFHVN DDPEAVAF+ +LA DFR+TF++DV IDL CYRR GHNEADEPSATQPLMYQ
Sbjct 416 QAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQPLMYQ 475
Query 476 VINKKPTTRTLYADQLVQQKVLDRAEADKLIEDYRSDLEAGNHVANALVLEPNTKMFVDW 535
I K PT R +YAD+L Q+KV +A +++ YR L+AG+ V P W
Sbjct 476 KIKKHPTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEW--RPMNMHSFTW 533
Query 536 KPYLGHDYTDVWDTTIDINRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKMQTGEMPLNW 595
PYL H++ + + +++ RL+EL + + +PE MQ +V+K+ DR M GE +W
Sbjct 534 SPYLNHEWDEEYPNKVEMKRLQELAKRISTVPEAVEMQSRVAKIYGDRQAMAAGEKLFDW 593
Query 596 GAAETLAYATLIDEGYLVRITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQPRFA 655
G AE LAYATL+DEG VR++GED GRGTF HRHA +HNQ +GSTY PL H+ Q F
Sbjct 594 GGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTYTPLQHIHNGQGAFR 653
Query 656 LYDSLLSEEAVLAFEYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCG 715
++DS+LSEEAVLAFEYGYAT P +L IWEAQFGDFAN AQVVIDQFI+SGE KW R+CG
Sbjct 654 VWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFISSGEQKWGRMCG 713
Query 716 LTMLLPHGFEGQGPEHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPM 775
L MLLPHG+EGQGPEHSSARLER+LQLCAE NMQV P+TPAQ++H LRRQA+R +R+P+
Sbjct 714 LVMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPL 773
Query 776 IVMSPKSLLRHKLATSTLEELATGTFQTVIDEVDQITKSDVTRLVLCGGKVYYDLIEKRR 835
+VMSPKSLLRH LA S+LEELA GTF I E+D++ V R+V+C GKVYYDL+E+RR
Sbjct 774 VVMSPKSLLRHPLAVSSLEELANGTFLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRR 833
Query 836 ELELNNIAVVRIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDI 895
+ +++A+VRIEQLYP+P + + EVL + +VKD VWCQEEP NQGAW + + + ++
Sbjct 834 KNNQHDVAIVRIEQLYPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQGAW-YCSQHHFREV 892
Query 896 LKSGKQIRISYAGREASAAPACGSPYLHAKQQAQLIHDALAIE 938
+ G +R YAGR ASA+PA G +H KQQ L++DAL +E
Sbjct 893 IPFGASLR--YAGRPASASPAVGYMSVHQKQQQDLVNDALNVE 933
>P0AFG3 2-oxoglutarate dehydrogenase E1 component [Escherichia
coli (strain K12)]
Length=933
Score = 1074 bits (2778), Expect = 0.0
Identities = 543/943 (58%), Positives = 681/943 (72%), Gaps = 15/943 (2%)
Query 1 MQDVADALRLDTE-LSADSAAYIEELYEQYLTSPTSVTEDWRQYFDKFP----KGDQPHS 55
MQ+ A LD+ LS + ++IE+LYE +LT P SV +WR F + P K DQ HS
Sbjct 1 MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRSTFQQLPGTGVKPDQFHS 60
Query 56 SVREQFLLLGRNSNRVQAVVQSSVSSDHERRQIGVLQLIAAYRNRGHQKAKLDPLGLAKR 115
RE F L ++++R + + D +Q+ VLQLI AYR RGHQ A LDPLGL ++
Sbjct 61 QTREYFRRLAKDASRYSSTISDP---DTNVKQVKVLQLINAYRFRGHQHANLDPLGLWQQ 117
Query 116 EDVPDLDLSAHGLTKSDLDTVFNTSNLAIGKAEATLGEMVETMESIYCGSIGAEYMHIVD 175
+ V DLD S H LT++D FN + A GK LGE++E ++ YCG IGAEYMHI
Sbjct 118 DKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEALKQTYCGPIGAEYMHITS 177
Query 176 TKEKRWIQQRLEGARGQFNFTNDQKKALLERLTAAEGLEKFLGNKYVGAKRFGVEGGESF 235
T+EKRWIQQR+E R FN +++KK L LTAAEGLE++LG K+ GAKRF +EGG++
Sbjct 178 TEEKRWIQQRIESGRATFN--SEEKKRFLSELTAAEGLERYLGAKFPGAKRFSLEGGDAL 235
Query 236 IPMMNEIIQRAGSVGCKEVVIGMPHRGRLNLLVNIMGKNPADLFGEFEGKSIHKKGSGDV 295
IPM+ E+I+ AG+ G +EVV+GM HRGRLN+LVN++GK P DLF EF GK G+GDV
Sbjct 236 IPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTGDV 295
Query 296 KYHQGFSSNVMTPGGEVHLALAFNPSHLEIVGPVVEGSVRARQVRRKDIGGDDVLPVIVH 355
KYH GFSS+ T GG VHLALAFNPSHLEIV PVV GSVRAR R + + VLP+ +H
Sbjct 296 KYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPITIH 355
Query 356 GDAAFAGQGVNQETFQMSQTRGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMV 415
GDAA GQGV QET MS+ RGY VGGTV IVINNQVGFTTS+P DARST YCTD+ KMV
Sbjct 356 GDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYCTDIGKMV 415
Query 416 QSPIFHVNGDDPEAVAFIAQLAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQ 475
Q+PIFHVN DDPEAVAF+ +LA DFR+TF++DV IDL CYRR GHNEADEPSATQPLMYQ
Sbjct 416 QAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQPLMYQ 475
Query 476 VINKKPTTRTLYADQLVQQKVLDRAEADKLIEDYRSDLEAGNHVANALVLEPNTKMFVDW 535
I K PT R +YAD+L Q+KV +A +++ YR L+AG+ V P W
Sbjct 476 KIKKHPTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEW--RPMNMHSFTW 533
Query 536 KPYLGHDYTDVWDTTIDINRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKMQTGEMPLNW 595
PYL H++ + + +++ RL+EL + + +PE MQ +V+K+ DR M GE +W
Sbjct 534 SPYLNHEWDEEYPNKVEMKRLQELAKRISTVPEAVEMQSRVAKIYGDRQAMAAGEKLFDW 593
Query 596 GAAETLAYATLIDEGYLVRITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQPRFA 655
G AE LAYATL+DEG VR++GED GRGTF HRHA +HNQ +GSTY PL H+ Q F
Sbjct 594 GGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTYTPLQHIHNGQGAFR 653
Query 656 LYDSLLSEEAVLAFEYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCG 715
++DS+LSEEAVLAFEYGYAT P +L IWEAQFGDFAN AQVVIDQFI+SGE KW R+CG
Sbjct 654 VWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFISSGEQKWGRMCG 713
Query 716 LTMLLPHGFEGQGPEHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPM 775
L MLLPHG+EGQGPEHSSARLER+LQLCAE NMQV P+TPAQ++H LRRQA+R +R+P+
Sbjct 714 LVMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPL 773
Query 776 IVMSPKSLLRHKLATSTLEELATGTFQTVIDEVDQITKSDVTRLVLCGGKVYYDLIEKRR 835
+VMSPKSLLRH LA S+LEELA GTF I E+D++ V R+V+C GKVYYDL+E+RR
Sbjct 774 VVMSPKSLLRHPLAVSSLEELANGTFLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRR 833
Query 836 ELELNNIAVVRIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDI 895
+ +++A+VRIEQLYP+P + + EVL + +VKD VWCQEEP NQGAW + + + ++
Sbjct 834 KNNQHDVAIVRIEQLYPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQGAW-YCSQHHFREV 892
Query 896 LKSGKQIRISYAGREASAAPACGSPYLHAKQQAQLIHDALAIE 938
+ G +R YAGR ASA+PA G +H KQQ L++DAL +E
Sbjct 893 IPFGASLR--YAGRPASASPAVGYMSVHQKQQQDLVNDALNVE 933
>Q59106 2-oxoglutarate dehydrogenase E1 component [Cupriavidus
necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442
/ H16 / Stanier 337)]
Length=950
Score = 1030 bits (2664), Expect = 0.0
Identities = 511/936 (55%), Positives = 660/936 (71%), Gaps = 18/936 (2%)
Query 14 LSADSAAYIEELYEQYLTSPTSVTEDWRQYFDKFPK---------GDQPHSSVREQFLLL 64
L +A Y+EELYE YL +P SV ++WR YFD D PH+ + F
Sbjct 11 LFGGNAPYVEELYEAYLQNPASVPDNWRAYFDAMQNVPAVDGSNGRDIPHAPIVASFAER 70
Query 65 GRNSNRVQAVVQSSVSSDHERRQIGVLQLIAAYRNRGHQKAKLDPLGLAKREDVPDLDLS 124
+ ++ +V +S SD R+++ QLIAAYRN G A LDPL +R +PDLD +
Sbjct 71 AKQGP-IRTIV-ASADSDMGRKRVAATQLIAAYRNIGSHWADLDPLKRQERPPLPDLDPA 128
Query 125 AHGLTKSDLDTVFNTSNLAIGKAEATLGEMVETMESIYCGSIGAEYMHIVDTKEKRWIQQ 184
+G +++DLD VFN SN GK +L E++ + YCG+IG E+M++ D +KRW Q+
Sbjct 129 FYGFSEADLDIVFNASNTYFGKESMSLRELLNNLRETYCGTIGFEFMYVSDQAQKRWWQE 188
Query 185 RLEGARGQFNFTNDQKKALLERLTAAEGLEKFLGNKYVGAKRFGVEGGESFIPMMNEIIQ 244
RLE R + FT ++KK +L+RLTAAEGLE+FL KYVG KRF +EGGESFI M+E+IQ
Sbjct 189 RLETTRSKPVFTLEKKKHILDRLTAAEGLERFLHTKYVGQKRFSLEGGESFIAAMDELIQ 248
Query 245 RAGSVGCKEVVIGMPHRGRLNLLVNIMGKNPADLFGEFEGKSIHKKGSGDVKYHQGFSSN 304
AGS G +E+VIGM HRGRLN+LVN +GK PADLF EFEGK + +GDVKYH+GFSS+
Sbjct 249 HAGSKGVQEIVIGMAHRGRLNVLVNTLGKMPADLFAEFEGKHVDDLPAGDVKYHKGFSSD 308
Query 305 VMTPGGEVHLALAFNPSHLEIVGPVVEGSVRARQVRRKDIGGDDVLPVIVHGDAAFAGQG 364
V T GG VHL+LAFNPSHLEIV PVVEGS +ARQ RR ++G +VLPV VHGDAAFAGQG
Sbjct 309 VSTEGGPVHLSLAFNPSHLEIVNPVVEGSAKARQERRGEVGHKEVLPVQVHGDAAFAGQG 368
Query 365 VNQETFQMSQTRGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMVQSPIFHVNG 424
V ET ++QTRGY GG++HIVINNQ+GFTTSDPRDARST YCTDV KM+++P+ HVNG
Sbjct 369 VVMETLNLAQTRGYGTGGSMHIVINNQIGFTTSDPRDARSTLYCTDVVKMIEAPVLHVNG 428
Query 425 DDPEAVAFIAQLAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQVINKKPTTR 484
DDPEAV + QLA DFR F+KDVV+D+ C+R+ GHNE D P+ TQPLMY+ I + P TR
Sbjct 429 DDPEAVVYAMQLAVDFRMEFKKDVVVDIICFRKLGHNEQDTPAVTQPLMYKKIAQHPGTR 488
Query 485 TLYADQLVQQKVLDRAEADKLIEDYRSDLEAGNHVANALVLEPNTKMFVDWKPYLGHDYT 544
LYAD+L Q ++ D+ ++ YR+ ++AG H A+ ++ K VDW P+L +T
Sbjct 489 KLYADKLAAQNLVPAEFGDEKVKAYRAAMDAGKHTADPVLSNFKNKFAVDWMPFLNRKWT 548
Query 545 DVWDTTIDINRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKMQTGEMPLNWGAAETLAYA 604
D DT + + LK L E + PE + V KV+ DR M G+ PL+WG E LA+A
Sbjct 549 DAADTAVPVTELKRLAERITTTPETLKLHPLVEKVVKDRANMGRGDQPLDWGMGEHLAFA 608
Query 605 TLIDEGYLVRITGEDVGRGTFSHRHAKLHNQV----DGSTYIPLCHVKENQPRFALYDSL 660
+L+ GY VRITG+D GRGTF+HRHA LH+Q D +Y+PL +V ENQ F + DS+
Sbjct 609 SLVSSGYPVRITGQDAGRGTFTHRHAVLHDQARERWDAGSYVPLQNVSENQAPFTVIDSV 668
Query 661 LSEEAVLAFEYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCGLTMLL 720
LSEEAVL FEYGY+ PN+L+IWEAQFGDF N AQVVIDQFI+SGE KW R GLT++L
Sbjct 669 LSEEAVLGFEYGYSAAEPNALVIWEAQFGDFVNGAQVVIDQFISSGEVKWGRASGLTLML 728
Query 721 PHGFEGQGPEHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSP 780
PHG+EGQGPEHSSAR+ERFLQLCA+ NMQV PTTPAQIFH LRRQ +R RKP+++M+P
Sbjct 729 PHGYEGQGPEHSSARIERFLQLCADHNMQVCQPTTPAQIFHLLRRQMIRLFRKPLVIMTP 788
Query 781 KSLLRHKLATSTLEELATGTFQTVIDEVDQITKSDVTRLVLCGGKVYYDLIEKRRELELN 840
KSLLR+K A S L +LA G F+TVI + +++ S V R+++C GKVYYDL+ R+E E N
Sbjct 789 KSLLRNKDAVSPLSDLAKGHFETVIPDHEELNASKVKRVIMCSGKVYYDLVNTRKEREAN 848
Query 841 NIAVVRIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILKSGK 900
+ AV+R+EQLYP+P + +A L YPN ++VWCQ+EP+NQGAW F+ + +++ K
Sbjct 849 DTAVIRLEQLYPFPHKAVAAELKKYPNATEIVWCQDEPQNQGAWFFVQHYIMENMTDGQK 908
Query 901 QIRISYAGREASAAPACGSPYLHAKQQAQLIHDALA 936
+ YAGR ASA+PA G H +QQ L+ A A
Sbjct 909 ---LGYAGRPASASPAVGYYAKHNEQQKALLEAAFA 941
>P45303 2-oxoglutarate dehydrogenase E1 component [Haemophilus
influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)]
Length=935
Score = 1008 bits (2606), Expect = 0.0
Identities = 502/931 (54%), Positives = 656/931 (70%), Gaps = 16/931 (2%)
Query 12 TELSADSAAYIEELYEQYLTSPTSVTEDWRQYFDKFPKG---DQPHSSVREQFLLLGR-N 67
T L + +YIEELYE YL+ P SV E WR+ FD PK +QPH+ VR+ F L R N
Sbjct 14 TALGGANQSYIEELYESYLSDPQSVEESWRKTFDSLPKTTALEQPHTPVRDYFRRLAREN 73
Query 68 SNRVQAVVQSSVSSDHERRQIGVLQLIAAYRNRGHQKAKLDPLGLA--KREDVPDLDLSA 125
N V+ + + + + VLQ I AYR RGH +A LDPL K VP+LD
Sbjct 74 HNEAVTVIDPAAGA----KLVKVLQFINAYRFRGHLEANLDPLNYYRWKVSFVPELDYRH 129
Query 126 HGLTKSDLDTVFNTSNLAIGKAEATLGEMVETMESIYCGSIGAEYMHIVDTKEKRWIQQR 185
HG T+ DL+ FN ++ + LGE+ + ++ YCGSIG E+MH+ D ++K W+Q +
Sbjct 130 HGFTEQDLNETFNINHYVYKRDTIKLGELAQMLKETYCGSIGLEFMHVQDMEQKMWLQSK 189
Query 186 LEGARGQFNFTNDQKKALLERLTAAEGLEKFLGNKYVGAKRFGVEGGESFIPMMNEIIQR 245
+E + FT++++ L LTAA+GLE++LG K+ GAKRF +EG ++FIP+M EII+
Sbjct 190 MESLLDKPLFTSEERVNFLRELTAADGLERYLGAKFPGAKRFSLEGSDAFIPLMKEIIRH 249
Query 246 AGSVGCKEVVIGMPHRGRLNLLVNIMGKNPADLFGEFEGKSIHKKGSGDVKYHQGFSSNV 305
+ G +VV+GM HRGRLN+LVN++GK P +LF EF GK ++ +GDVKYHQGFSS+
Sbjct 250 SSRQGVNDVVMGMAHRGRLNMLVNVLGKKPENLFDEFAGKHSSER-TGDVKYHQGFSSDF 308
Query 306 MTPGGEVHLALAFNPSHLEIVGPVVEGSVRARQVRRKDIGGDDVLPVIVHGDAAFAGQGV 365
VHL LAFNPSHLEIV PVV GSVR+RQ R D VL + VHGD+A AGQGV
Sbjct 309 AVDDKRVHLTLAFNPSHLEIVSPVVIGSVRSRQTRMNDTEHSKVLAITVHGDSAVAGQGV 368
Query 366 NQETFQMSQTRGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMVQSPIFHVNGD 425
QET MS TRGY+VGGT+ IVINNQ+GFTTS+P D RSTEYCTD+AKM+Q+PI HVNGD
Sbjct 369 VQETLNMSNTRGYSVGGTIRIVINNQIGFTTSNPNDTRSTEYCTDIAKMIQAPIIHVNGD 428
Query 426 DPEAVAFIAQLAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQVINKKPTTRT 485
DPEAVAF A++A ++R+ F++D+ IDL YRR GHNEADEP ATQP+MY +I K PT R
Sbjct 429 DPEAVAFAARMAVEYRNLFKRDIFIDLISYRRHGHNEADEPLATQPMMYSIIKKHPTPRK 488
Query 486 LYADQLVQQKVLDRAEADKLIEDYRSDLEAGNHVANALVLEPNTKMFVDWKPYLGHDYTD 545
+YAD+LV + V+ + ++ DYR L+ G+ V + KM DW YL +D+T
Sbjct 489 VYADRLVSEGVMTEEQVTEMANDYRDALDNGDRVVSEWREMDTAKM--DWLQYLNYDWTA 546
Query 546 VWDTTIDINRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKMQTGEMPLNWGAAETLAYAT 605
+++ R L + + + PE +V K+ +DR M GE L+WG AET+AYAT
Sbjct 547 PYESKFSQERFLTLAKRVCEYPESLRAHPRVEKIYNDRKAMYQGEKLLDWGMAETMAYAT 606
Query 606 LIDEGYLVRITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQPRFALYDSLLSEEA 665
L+DEG VR++GED GRGTF HRHA +HNQ DG+ Y+PL H+ NQ RF ++DS+LSEE+
Sbjct 607 LLDEGVNVRLSGEDAGRGTFFHRHAVVHNQNDGTGYVPLTHLHANQGRFEVWDSVLSEES 666
Query 666 VLAFEYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCGLTMLLPHGFE 725
VLAFEYGYATT P +L IWEAQFGDFAN AQ+VIDQFI+SGE KW R+CGL MLLPHG+E
Sbjct 667 VLAFEYGYATTDPKTLTIWEAQFGDFANGAQIVIDQFISSGEQKWGRMCGLVMLLPHGYE 726
Query 726 GQGPEHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLR 785
GQGPEHSSARLER+LQLCAE NMQV P+TPAQ++H LRRQ++R +R+P+I +SPKSLLR
Sbjct 727 GQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQSLRKMRRPLIAISPKSLLR 786
Query 786 HKLATSTLEELATGTFQTVIDEVDQITKSDVTRLVLCGGKVYYDLIEKRRELELNNIAVV 845
H LA S+L+EL GTFQTVI E+D++ DV R+V+C GKVYYDL+E+RR ++A++
Sbjct 787 HPLAVSSLDELINGTFQTVIGEIDELDPKDVKRVVMCSGKVYYDLLEQRRANNQKDVAII 846
Query 846 RIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILKSGKQIRIS 905
RIEQLYP+P + + + L Y +V D VWCQEEP NQGAW + + ++ + + +++
Sbjct 847 RIEQLYPFPHEDVKKALEPYAHVTDYVWCQEEPLNQGAW-YCSKHNFESAIP--ESVKLK 903
Query 906 YAGREASAAPACGSPYLHAKQQAQLIHDALA 936
YAGR ASA+PA G LH KQQ QL+ DAL+
Sbjct 904 YAGRPASASPAVGYMSLHTKQQKQLVEDALS 934
>P51056 2-oxoglutarate dehydrogenase E1 component [Coxiella burnetii
(strain RSA 493 / Nine Mile phase I)]
Length=934
Score = 922 bits (2384), Expect = 0.0
Identities = 464/930 (50%), Positives = 623/930 (67%), Gaps = 16/930 (2%)
Query 14 LSADSAAYIEELYEQYLTSPTSVTEDWRQYFDKFPKG----DQPHSSVREQFLLLGRNSN 69
L+ ++A YIE LYE +L P SV E+WR YF G D H+++RE+F L R
Sbjct 15 LADNNAGYIETLYENFLKDPHSVNEEWRSYFRTLTNGASTPDISHATIREEFRELARKPR 74
Query 70 RVQAVVQSSVSSDHERRQIGVLQLIAAYRNRGHQKAKLDPLGLAKREDVPDLDLSAHGLT 129
+ + + Q V LI YR GH AK++PLG + D L+L + LT
Sbjct 75 SISPTAITPAAE-----QAAVDLLIEGYRRFGHLNAKINPLGDNRPVD-SRLELGHYNLT 128
Query 130 KSDLDTVFNTSNLAIGKAEATLGEMVETMESIYCGSIGAEYMHIVDTKEKRWIQQRLEGA 189
+SD + F T L + K +ATL E+ + IYCGSIG +Y I D +E+ W++ +E
Sbjct 129 ESDFNKTFATYGL-LNKPKATLKEIYTRLREIYCGSIGVQYSTISDERERNWLRDYVEQR 187
Query 190 RGQFNFTNDQKKALLERLTAAEGLEKFLGNKYVGAKRFGVEGGESFIPMMNEIIQRAGSV 249
F + K+ +L++L AE LEK+L KYVG R+ +EGG+S IP+++E+ +RA
Sbjct 188 LPSIEFDKETKRNILQQLVTAESLEKYLDTKYVGQVRYSLEGGDSLIPLLDELTKRARHQ 247
Query 250 GCKEVVIGMPHRGRLNLLVNIMGKNPADLFGEFEGKSIHKKGSGDVKYHQGFSSNVMTPG 309
+E+VI M HRGR+N+L+NIMG++ A+LF EFEGK + SGDVKYH+G+S +V T
Sbjct 248 KIEEIVICMAHRGRVNVLLNIMGQSAAELFQEFEGKKDYGLMSGDVKYHRGYSRDVKTDA 307
Query 310 GEVHLALAFNPSHLEIVGPVVEGSVRARQVRRKDIGGDDVLPVIVHGDAAFAGQGVNQET 369
G +HL+LAFNPSHLE + PV GSVRARQ R+ D + V++HGDA+F+G+G+ E
Sbjct 308 GPIHLSLAFNPSHLEFICPVAMGSVRARQERQNGHKRDYAMTVMIHGDASFSGEGIVMEA 367
Query 370 FQMSQTRGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMVQSPIFHVNGDDPEA 429
MSQTR + VGG++HI++NNQVGFTTS+P DARS+ YC+D+AKM+ +P+FHVNGDDPEA
Sbjct 368 LSMSQTRAHHVGGSIHIILNNQVGFTTSNPHDARSSMYCSDIAKMLDAPVFHVNGDDPEA 427
Query 430 VAFIAQLAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQVINKKPTTRTLYAD 489
V + QLA D+R F KDV IDL CYRR GH E D+P TQP MY+VI + PTTRTLYA
Sbjct 428 VVAVTQLALDYRMAFHKDVFIDLVCYRRHGHQEVDDPMPTQPAMYKVIQEHPTTRTLYAK 487
Query 490 QLVQQKVLDRAEADKLIEDYRSDLEAGNHVANALVLEPNTKMFVDWKPYLGHDYTDVWDT 549
L+++K+ E D+ I+DYR L+ G + L + +W PYLG D+T + DT
Sbjct 488 NLIEKKLCTAEEVDQWIDDYRDRLDRGRQLVETLPEGLSAHYAANWTPYLGQDWTTLVDT 547
Query 550 TIDINRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKMQTGEMPLNWGAAETLAYATLIDE 609
T+ + +LK LG+ LP + R+V + RL+M G+ P++WG AE LAYA+L++E
Sbjct 548 TLPLKKLKALGKKFSTLPNTLHLHRKVEAIYKARLEMAEGKTPMDWGFAEMLAYASLLEE 607
Query 610 GYLVRITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQPRFALYDSLLSEEAVLAF 669
G+ VR+ G+D RGTF HRHA + +Q G Y PL H+ + Q +YDSLL E L F
Sbjct 608 GFSVRLVGQDSRRGTFFHRHAVVFDQETGKEYEPLKHLSDKQAAPHIYDSLLCEAGALGF 667
Query 670 EYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCGLTMLLPHGFEGQGP 729
EYGY+T PNSL+IWEAQFGDFAN AQV++DQFI+SG KW R+ G+ + LPHG+EG+GP
Sbjct 668 EYGYSTADPNSLVIWEAQFGDFANVAQVIVDQFISSGWQKWNRLSGIVLFLPHGYEGKGP 727
Query 730 EHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLRHKLA 789
EHSSARLER+LQLCA++NMQV PTTP+QIFH LRRQ +RP RKP++V++PKS+LR+KLA
Sbjct 728 EHSSARLERYLQLCAQNNMQVCAPTTPSQIFHLLRRQVLRPYRKPLVVLTPKSVLRNKLA 787
Query 790 TSTLEELATGTFQTVIDEVDQITKSDVTRLVLCGGKVYYDLIEKRREL--ELNNIAVVRI 847
S+LE+LA G + +I E+++ +TR++LC GKVYYDL+ KRRE +LN+IA++RI
Sbjct 788 VSSLEDLARGQLKLLIPEIEKHDPKKITRVILCSGKVYYDLLAKRREHKGKLNHIAMIRI 847
Query 848 EQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILKSGKQIRISYA 907
EQLYP+P L L YPN K V+WCQEEPKNQGAW RL I + Y
Sbjct 848 EQLYPFPYDELKAELEKYPNAKQVIWCQEEPKNQGAWFCTRHRL---IKCMRDDQTLEYV 904
Query 908 GREASAAPACGSPYLHAKQQAQLIHDALAI 937
GR A AAPA G L+ K Q QL++ AL I
Sbjct 905 GRSAFAAPAAGYSALYVKLQEQLVNQALEI 934
>P57388 2-oxoglutarate dehydrogenase E1 component [Buchnera aphidicola
subsp. Acyrthosiphon pisum (strain APS)]
Length=909
Score = 825 bits (2131), Expect = 0.0
Identities = 423/925 (46%), Positives = 611/925 (66%), Gaps = 32/925 (3%)
Query 14 LSADSAAYIEELYEQYLTSPTSVTEDWRQYFDKFPKGDQPHSSVREQFLLLGRNSNRVQA 73
LS ++ YIE +Y+ +LT+ S+ + W + F +F + EQ RN+ +
Sbjct 15 LSRENQNYIETIYKSFLTNAQSIDDMWHKAFLEFSE---------EQKNTYERNNTKNNK 65
Query 74 VVQSSVSSDHERRQIGVLQLIAAYRNRGHQKAKLDPLGLAKREDVPDLDLSAHGLTKSDL 133
+ DH +I A+R+ G+Q++ +DPL L KR + DLDLS + T+ +
Sbjct 66 YLLIK-KIDH---------MIHAFRSEGYQQSLIDPLKLKKRTKIHDLDLSFYNFTEEET 115
Query 134 DTVFNTSNLAIGKAEATLGEMVETMESIYCGSIGAEYMHIVDTKEKRWIQQRLEGARGQF 193
+ + + + + YCGSIG EYM++ + EK+WI +E +
Sbjct 116 RQTVEINFKNCTNFRTNIISLYKILYKKYCGSIGFEYMYVNNLLEKQWITNHIESFFNEN 175
Query 194 NFTNDQKKALLERLTAAEGLEKFLGNKYVGAKRFGVEGGESFIPMMNEIIQRAGSVGCKE 253
FT ++K L+ LT AE LEK++G K+ GAKRF +EG E+ IP+++E+I+ + +
Sbjct 176 VFTIEEKINFLKELTYAETLEKYIGKKFPGAKRFSLEGAETLIPVLHEVIRFSKKNNISK 235
Query 254 VVIGMPHRGRLNLLVNIMGKNPADLFGEFEGKSIHKKGSGDVKYHQGFSSNVMTPGGEVH 313
+V+GM HRGRLN+L+N++ K+P LF EF ++ +K SGDVKYH G ++ + ++
Sbjct 236 IVLGMAHRGRLNVLINVLNKSPKVLFDEFSNLNLFQKISGDVKYHMGGTAEIQYEK-KII 294
Query 314 LALAFNPSHLEIVGPVVEGSVRARQVRRKDIGGDDVLPVIVHGDAAFAGQGVNQETFQMS 373
+A NPSHLEI+ PVV G R+ K+I ++VLP+ +HGDA+ GQGV QET MS
Sbjct 295 FHMACNPSHLEIINPVVSGISRSYIDNMKNID-NEVLPISIHGDASVIGQGVVQETLNMS 353
Query 374 QTRGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMVQSPIFHVNGDDPEAVAFI 433
QT GY VGGTVHI+INNQ+GFTTS+P+ RS+EYCTDVAK++Q+P+FHVN DD EA F
Sbjct 354 QTEGYKVGGTVHIIINNQIGFTTSNPKHLRSSEYCTDVAKIIQAPVFHVNADDLEASIFA 413
Query 434 AQLAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQVINKKPTTRTLYADQLVQ 493
QLA FR F+KDV IDL CYRR GHNE DEPS TQP+MYQ I PT+RT+Y+D L+
Sbjct 414 IQLALHFRKIFKKDVFIDLVCYRRNGHNEVDEPSVTQPIMYQKIKNHPTSRTIYSDVLIS 473
Query 494 QKVLDRAEADKLIEDYRSDLEAGNHV-ANALVLEPNTKMFVDWKPYLGHDYTDVWDTTID 552
+K++ + +++ Y S L+ G+++ + + + + F++ K ++
Sbjct 474 KKIITSEKNQEIMNQYLSKLQKGHYIFSKSKNIHFKNEFFLEEKKI------KKIKKDVN 527
Query 553 INRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKMQTGEMPLNWGAAETLAYATLIDEGYL 612
+ LK L + ++P+ M ++V K+ ++RL+M +WGAAETLAYAT+++EG
Sbjct 528 FSDLKNLACLINQIPDSVKMHQRVKKIYEERLEMAQRLKLFDWGAAETLAYATILNEGIS 587
Query 613 VRITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQPRFALYDSLLSEEAVLAFEYG 672
RI+GEDV RGTF HRHA +HNQ++GS YIPL ++ + Q +F ++DS+LSEEAVLAFEYG
Sbjct 588 CRISGEDVSRGTFFHRHAFIHNQINGSIYIPLNNISKKQGKFQIWDSVLSEEAVLAFEYG 647
Query 673 YATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCGLTMLLPHGFEGQGPEHS 732
Y+ + PN+L IWEAQFGDF N AQ+VIDQFI+SGE KW + L +LLPHG+EGQGPEHS
Sbjct 648 YSLSSPNTLTIWEAQFGDFINGAQIVIDQFISSGEQKWNKKSNLVVLLPHGYEGQGPEHS 707
Query 733 SARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLRHKLATST 792
S+R+ERFLQLCAE+NMQ+ PTT +QIFH R+Q I KP+I+ +PKSLLR+ +A+S+
Sbjct 708 SSRIERFLQLCAEENMQICIPTTSSQIFHIFRKQIFDKILKPLIIFTPKSLLRNPMASSS 767
Query 793 LEELATGTFQTVIDEVDQITKSDVTRLVLCGGKVYYDLIEKRRELELNNIAVVRIEQLYP 852
++L G FQ ++DEVD + K ++ RL+ C GK+YYDL+ RRE ++N+I ++RIEQLYP
Sbjct 768 FDDLVYGKFQKILDEVDNVNKKEI-RLIFCSGKIYYDLLRNRREKKINSIILIRIEQLYP 826
Query 853 YPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILKSGKQIRISYAGREAS 912
+PE + ++L Y +KD +WCQEEP NQGAW +I L +IL ++ Y GR +S
Sbjct 827 FPEGEILKILKNYFYIKDFIWCQEEPYNQGAWFYIKDCL-SNILPLDASLK--YIGRSSS 883
Query 913 AAPACGSPYLHAKQQAQLIHDALAI 937
A+PA G +H KQQ ++I++AL I
Sbjct 884 ASPAVGYISIHKKQQEKIIYNALNI 908
>Q8FYF7 2-oxoglutarate dehydrogenase E1 component [Brucella suis
biovar 1 (strain 1330)]
Length=1004
Score = 803 bits (2073), Expect = 0.0
Identities = 452/998 (45%), Positives = 621/998 (62%), Gaps = 75/998 (8%)
Query 6 DALRLDTELSADSAAYIEELYEQYLTSPTSVTEDWRQYFDK----------------FPK 49
D L + L +A YIEELY +Y P SV WR +F K + +
Sbjct 13 DVFALTSFLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGPSWTR 72
Query 50 GDQPHSSVREQFLLLGRNSNRVQAVVQSSVS---------------------SDHERRQI 88
+ P ++ E L N V+ V + + R +
Sbjct 73 KNWPIAANGELVSALDGNWAEVEKHVTDKLKGKAAKGEAKGAAGTPLTAEEITQAARDSV 132
Query 89 GVLQLIAAYRNRGHQKAKLDPLGLAKR-EDVPDLDLSAHGLTKSDLDTVFNTSNLAIGKA 147
+ +I AYR RGH A LDPLGLA++ D +L+ +G T +D + N+ +G
Sbjct 133 RAIMMIRAYRMRGHLHANLDPLGLAEKPNDYNELEPENYGFTPADYNRKIFIDNV-LGLE 191
Query 148 EATLGEMVETMESIYCGSIGAEYMHIVDTKEKRWIQQRLEGARGQFNFTNDQKKALLERL 207
AT+ EM++ ++ YCG+IG E+MHI D EK WIQ+R+EG + FT + KKA+L +L
Sbjct 192 YATVPEMLDILKRTYCGAIGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKKAILSKL 251
Query 208 TAAEGLEKFLGNKYVGAKRFGVEGGESFIPMMNEIIQRAGSVGCKEVVIGMPHRGRLNLL 267
AEG E+F+ KY G KRFG++GGES IP + +I++R G +G KEVV+GM HRGRLN+L
Sbjct 252 IEAEGFEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGQMGLKEVVLGMAHRGRLNVL 311
Query 268 VNIMGKNPADLFGEFEGKSIHK---KGSGDVKYHQGFSSNVMTPGGEVHLALAFNPSHLE 324
+MGK +F EF+G S +GSGDVKYH G SS+ G +VHL+L NPSHLE
Sbjct 312 SQVMGKPHRAIFHEFKGGSYTPDDVEGSGDVKYHLGASSDREFDGNKVHLSLTANPSHLE 371
Query 325 IVGPVVEGSVRARQVRRKDIGGDD---------VLPVIVHGDAAFAGQGVNQETFQMSQT 375
IV PVV G RA+Q DD VLP+++HGDAAFAGQGV E +S
Sbjct 372 IVNPVVMGKARAKQDLLVGRTRDDMVPLSERAKVLPLLLHGDAAFAGQGVVAECLGLSGL 431
Query 376 RGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMVQSPIFHVNGDDPEAVAFIAQ 435
+G+ V GT+H +INNQ+GFTT+ P +RS+ Y +DVAKM+++PIFHVNGDDPEAV F A+
Sbjct 432 KGHRVAGTLHFIINNQIGFTTN-PAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVFAAK 490
Query 436 LAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQVINKKPTTRTLYADQLVQQK 495
+A +FR TF K VVID+FCYRR GHNE DEPS TQPLMY+ I TT LY ++L+ +
Sbjct 491 VATEFRMTFHKPVVIDMFCYRRFGHNEGDEPSFTQPLMYKAIRAHKTTVQLYGEKLIAEG 550
Query 496 VLDRAEADKLIEDYRSDLEAGNHVANALVLEPNTKMFVD--WKPYLGHDYTDVW---DTT 550
++ + + D++ D+R LE + +PN ++D W D D T
Sbjct 551 LVTQDDIDRMKADWRQKLEGEFEAGQSY--KPNKADWLDGAWAGLRTADNADEQRRGKTA 608
Query 551 IDINRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKM-QTGEMPLNWGAAETLAYATLIDE 609
+ + LKE+G+ + ++P+ F + R + + +D+R KM +TGE ++W AE+LA+ +L E
Sbjct 609 VPVKTLKEIGKKLVEVPKDFHVHRTIQRFLDNRAKMMETGE-GIDWATAESLAFGSLAVE 667
Query 610 GYLVRITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQPRFALYDSLLSEEAVLAF 669
G+ +R++G+DV RGTFS RH L++Q + + YIPL ++++ Q + +S+LSEEAVL +
Sbjct 668 GHPIRLSGQDVERGTFSQRHTVLYDQENQNRYIPLNNLQKGQAIYEAINSMLSEEAVLGY 727
Query 670 EYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCGLTMLLPHGFEGQGP 729
EYGY+ + P +L++WEAQFGDFAN AQVV DQFI+SGE KW R+ GL LLPHGFEGQGP
Sbjct 728 EYGYSLSDPRALVLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGFEGQGP 787
Query 730 EHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLRHKLA 789
EHSSARLER+LQLCAEDNMQV TTPA FH LRRQ R RKP+I+M+PKSLLRHK A
Sbjct 788 EHSSARLERYLQLCAEDNMQVANVTTPANYFHILRRQMKRDFRKPLIMMTPKSLLRHKRA 847
Query 790 TSTLEELA-TGTFQTVIDEVDQITKSD---------VTRLVLCGGKVYYDLIEKRRELEL 839
STL EL+ +F ++ + Q K + + R+VLC GKVYYDL E+R + +
Sbjct 848 ISTLAELSGESSFHRLLWDDAQYNKDEGIKLQKDAKIRRVVLCSGKVYYDLYEEREKRGI 907
Query 840 NNIAVVRIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILK-- 897
+++ ++R+EQLYP+P + L L+ + + ++VWCQEEPKN GAW FI P L + +L
Sbjct 908 DDVYLLRVEQLYPFPAKALINELSRFRHA-EMVWCQEEPKNMGAWSFIDPYL-EWVLAHI 965
Query 898 SGKQIRISYAGREASAAPACGSPYLHAKQQAQLIHDAL 935
K R+ YAGR A+A+PA G H Q A + DAL
Sbjct 966 DAKHQRVRYAGRPAAASPATGLMSKHLAQLAAFLEDAL 1003
>B0CIS7 2-oxoglutarate dehydrogenase E1 component [Brucella suis
(strain ATCC 23445 / NCTC 10510)]
Length=1004
Score = 803 bits (2073), Expect = 0.0
Identities = 452/998 (45%), Positives = 621/998 (62%), Gaps = 75/998 (8%)
Query 6 DALRLDTELSADSAAYIEELYEQYLTSPTSVTEDWRQYFDK----------------FPK 49
D L + L +A YIEELY +Y P SV WR +F K + +
Sbjct 13 DVFALTSFLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGPSWTR 72
Query 50 GDQPHSSVREQFLLLGRNSNRVQAVVQSSVS---------------------SDHERRQI 88
+ P ++ E L N V+ V + + R +
Sbjct 73 KNWPIAANGELVSALDGNWAEVEKHVTDKLKGKAAKGEAKGAAGTPLTAEEITQAARDSV 132
Query 89 GVLQLIAAYRNRGHQKAKLDPLGLAKR-EDVPDLDLSAHGLTKSDLDTVFNTSNLAIGKA 147
+ +I AYR RGH A LDPLGLA++ D +L+ +G T +D + N+ +G
Sbjct 133 RAIMMIRAYRMRGHLHANLDPLGLAEKPNDYNELEPENYGFTPADYNRKIFIDNV-LGLE 191
Query 148 EATLGEMVETMESIYCGSIGAEYMHIVDTKEKRWIQQRLEGARGQFNFTNDQKKALLERL 207
AT+ EM++ ++ YCG+IG E+MHI D EK WIQ+R+EG + FT + KKA+L +L
Sbjct 192 YATVPEMLDILKRTYCGAIGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKKAILSKL 251
Query 208 TAAEGLEKFLGNKYVGAKRFGVEGGESFIPMMNEIIQRAGSVGCKEVVIGMPHRGRLNLL 267
AEG E+F+ KY G KRFG++GGES IP + +I++R G +G KEVV+GM HRGRLN+L
Sbjct 252 IEAEGFEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGQMGLKEVVLGMAHRGRLNVL 311
Query 268 VNIMGKNPADLFGEFEGKSIHK---KGSGDVKYHQGFSSNVMTPGGEVHLALAFNPSHLE 324
+MGK +F EF+G S +GSGDVKYH G SS+ G +VHL+L NPSHLE
Sbjct 312 SQVMGKPHRAIFHEFKGGSYTPDDVEGSGDVKYHLGASSDREFDGNKVHLSLTANPSHLE 371
Query 325 IVGPVVEGSVRARQVRRKDIGGDD---------VLPVIVHGDAAFAGQGVNQETFQMSQT 375
IV PVV G RA+Q DD VLP+++HGDAAFAGQGV E +S
Sbjct 372 IVNPVVMGKARAKQDLLVGRTRDDMVPLSERPKVLPLLLHGDAAFAGQGVVAECLGLSGL 431
Query 376 RGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMVQSPIFHVNGDDPEAVAFIAQ 435
+G+ V GT+H +INNQ+GFTT+ P +RS+ Y +DVAKM+++PIFHVNGDDPEAV F A+
Sbjct 432 KGHRVAGTLHFIINNQIGFTTN-PAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVFAAK 490
Query 436 LAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQVINKKPTTRTLYADQLVQQK 495
+A +FR TF K VVID+FCYRR GHNE DEPS TQPLMY+ I TT LY ++L+ +
Sbjct 491 VATEFRMTFHKPVVIDMFCYRRFGHNEGDEPSFTQPLMYKAIRAHKTTVQLYGEKLIAEG 550
Query 496 VLDRAEADKLIEDYRSDLEAGNHVANALVLEPNTKMFVD--WKPYLGHDYTDVW---DTT 550
++ + + D++ D+R LE + +PN ++D W D D T
Sbjct 551 LVTQDDIDRMKADWRQKLEGEFEAGQSY--KPNKADWLDGAWAGLRTADNADEQRRGKTA 608
Query 551 IDINRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKM-QTGEMPLNWGAAETLAYATLIDE 609
+ + LKE+G+ + ++P+ F + R + + +D+R KM +TGE ++W AE+LA+ +L E
Sbjct 609 VPVKTLKEIGKKLVEVPKDFHVHRTIQRFLDNRAKMMETGE-GIDWATAESLAFGSLAVE 667
Query 610 GYLVRITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQPRFALYDSLLSEEAVLAF 669
G+ +R++G+DV RGTFS RH L++Q + + YIPL ++++ Q + +S+LSEEAVL +
Sbjct 668 GHPIRLSGQDVERGTFSQRHTVLYDQENQNRYIPLNNLQKGQAIYEAINSMLSEEAVLGY 727
Query 670 EYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCGLTMLLPHGFEGQGP 729
EYGY+ + P +L++WEAQFGDFAN AQVV DQFI+SGE KW R+ GL LLPHGFEGQGP
Sbjct 728 EYGYSLSDPRALVLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGFEGQGP 787
Query 730 EHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLRHKLA 789
EHSSARLER+LQLCAEDNMQV TTPA FH LRRQ R RKP+I+M+PKSLLRHK A
Sbjct 788 EHSSARLERYLQLCAEDNMQVANVTTPANYFHILRRQMKRDFRKPLIMMTPKSLLRHKRA 847
Query 790 TSTLEELA-TGTFQTVIDEVDQITKSD---------VTRLVLCGGKVYYDLIEKRRELEL 839
STL EL+ +F ++ + Q K + + R+VLC GKVYYDL E+R + +
Sbjct 848 ISTLAELSGESSFHRLLWDDAQYNKDEGIKLQKDAKIRRVVLCSGKVYYDLYEEREKRGI 907
Query 840 NNIAVVRIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILK-- 897
+++ ++R+EQLYP+P + L L+ + + ++VWCQEEPKN GAW FI P L + +L
Sbjct 908 DDVYLLRVEQLYPFPAKALINELSRFRHA-EMVWCQEEPKNMGAWSFIDPYL-EWVLAHI 965
Query 898 SGKQIRISYAGREASAAPACGSPYLHAKQQAQLIHDAL 935
K R+ YAGR A+A+PA G H Q A + DAL
Sbjct 966 DAKHQRVRYAGRPAAASPATGLMSKHLAQLAAFLEDAL 1003
>A9M8Q9 2-oxoglutarate dehydrogenase E1 component [Brucella canis
(strain ATCC 23365 / NCTC 10854)]
Length=1004
Score = 803 bits (2073), Expect = 0.0
Identities = 452/998 (45%), Positives = 621/998 (62%), Gaps = 75/998 (8%)
Query 6 DALRLDTELSADSAAYIEELYEQYLTSPTSVTEDWRQYFDK----------------FPK 49
D L + L +A YIEELY +Y P SV WR +F K + +
Sbjct 13 DVFALTSFLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGPSWTR 72
Query 50 GDQPHSSVREQFLLLGRNSNRVQAVVQSSVS---------------------SDHERRQI 88
+ P ++ E L N V+ V + + R +
Sbjct 73 KNWPIAANGELVSALDGNWAEVEKHVADKLKGKAAKGEAKGAAGTPLTAEEITQAARDSV 132
Query 89 GVLQLIAAYRNRGHQKAKLDPLGLAKR-EDVPDLDLSAHGLTKSDLDTVFNTSNLAIGKA 147
+ +I AYR RGH A LDPLGLA++ D +L+ +G T +D + N+ +G
Sbjct 133 RAIMMIRAYRMRGHLHANLDPLGLAEKPNDYNELEPENYGFTPADYNRKIFIDNV-LGLE 191
Query 148 EATLGEMVETMESIYCGSIGAEYMHIVDTKEKRWIQQRLEGARGQFNFTNDQKKALLERL 207
AT+ EM++ ++ YCG+IG E+MHI D EK WIQ+R+EG + FT + KKA+L +L
Sbjct 192 YATVPEMLDILKRTYCGAIGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKKAILSKL 251
Query 208 TAAEGLEKFLGNKYVGAKRFGVEGGESFIPMMNEIIQRAGSVGCKEVVIGMPHRGRLNLL 267
AEG E+F+ KY G KRFG++GGES IP + +I++R G +G KEVV+GM HRGRLN+L
Sbjct 252 IEAEGFEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGQMGLKEVVLGMAHRGRLNVL 311
Query 268 VNIMGKNPADLFGEFEGKSIHK---KGSGDVKYHQGFSSNVMTPGGEVHLALAFNPSHLE 324
+MGK +F EF+G S +GSGDVKYH G SS+ G +VHL+L NPSHLE
Sbjct 312 SQVMGKPHRAIFHEFKGGSYTPDDVEGSGDVKYHLGASSDREFDGNKVHLSLTANPSHLE 371
Query 325 IVGPVVEGSVRARQVRRKDIGGDD---------VLPVIVHGDAAFAGQGVNQETFQMSQT 375
IV PVV G RA+Q DD VLP+++HGDAAFAGQGV E +S
Sbjct 372 IVNPVVMGKARAKQDLLVGRTRDDMVPLSERAKVLPLLLHGDAAFAGQGVVAECLGLSGL 431
Query 376 RGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMVQSPIFHVNGDDPEAVAFIAQ 435
+G+ V GT+H +INNQ+GFTT+ P +RS+ Y +DVAKM+++PIFHVNGDDPEAV F A+
Sbjct 432 KGHRVAGTLHFIINNQIGFTTN-PAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVFAAK 490
Query 436 LAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQVINKKPTTRTLYADQLVQQK 495
+A +FR TF K VVID+FCYRR GHNE DEPS TQPLMY+ I TT LY ++L+ +
Sbjct 491 VATEFRMTFHKPVVIDMFCYRRFGHNEGDEPSFTQPLMYKAIRAHKTTVQLYGEKLIAEG 550
Query 496 VLDRAEADKLIEDYRSDLEAGNHVANALVLEPNTKMFVD--WKPYLGHDYTDVW---DTT 550
++ + + D++ D+R LE + +PN ++D W D D T
Sbjct 551 LVTQDDIDRMKADWRQKLEGEFEAGQSY--KPNKADWLDGAWAGLRTADNADEQRRGKTA 608
Query 551 IDINRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKM-QTGEMPLNWGAAETLAYATLIDE 609
+ + LKE+G+ + ++P+ F + R + + +D+R KM +TGE ++W AE+LA+ +L E
Sbjct 609 VPVKTLKEIGKKLVEVPKDFHVHRTIQRFLDNRAKMMETGE-GIDWATAESLAFGSLAVE 667
Query 610 GYLVRITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQPRFALYDSLLSEEAVLAF 669
G+ +R++G+DV RGTFS RH L++Q + + YIPL ++++ Q + +S+LSEEAVL +
Sbjct 668 GHPIRLSGQDVERGTFSQRHTVLYDQENQNRYIPLNNLQKGQAIYEAINSMLSEEAVLGY 727
Query 670 EYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCGLTMLLPHGFEGQGP 729
EYGY+ + P +L++WEAQFGDFAN AQVV DQFI+SGE KW R+ GL LLPHGFEGQGP
Sbjct 728 EYGYSLSDPRALVLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGFEGQGP 787
Query 730 EHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLRHKLA 789
EHSSARLER+LQLCAEDNMQV TTPA FH LRRQ R RKP+I+M+PKSLLRHK A
Sbjct 788 EHSSARLERYLQLCAEDNMQVANVTTPANYFHILRRQMKRDFRKPLIMMTPKSLLRHKRA 847
Query 790 TSTLEELA-TGTFQTVIDEVDQITKSD---------VTRLVLCGGKVYYDLIEKRRELEL 839
STL EL+ +F ++ + Q K + + R+VLC GKVYYDL E+R + +
Sbjct 848 ISTLAELSGESSFHRLLWDDAQYNKDEGIKLQKDAKIRRVVLCSGKVYYDLYEEREKRGI 907
Query 840 NNIAVVRIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILK-- 897
+++ ++R+EQLYP+P + L L+ + + ++VWCQEEPKN GAW FI P L + +L
Sbjct 908 DDVYLLRVEQLYPFPAKALINELSRFRHA-EMVWCQEEPKNMGAWSFIDPYL-EWVLAHI 965
Query 898 SGKQIRISYAGREASAAPACGSPYLHAKQQAQLIHDAL 935
K R+ YAGR A+A+PA G H Q A + DAL
Sbjct 966 DAKHQRVRYAGRPAAASPATGLMSKHLAQLAAFLEDAL 1003
>A6WXF0 2-oxoglutarate dehydrogenase E1 component [Brucella anthropi
(strain ATCC 49188 / DSM 6882 / CCUG 24695 / JCM 21032
/ LMG 3331 / NBRC 15819 / NCTC 12168 / Alc 37)]
Length=1001
Score = 802 bits (2071), Expect = 0.0
Identities = 449/998 (45%), Positives = 622/998 (62%), Gaps = 75/998 (8%)
Query 6 DALRLDTELSADSAAYIEELYEQYLTSPTSVTEDWRQYFDK----------------FPK 49
D L + L +A YIEELY +Y P SV WR +F K + +
Sbjct 9 DVFALTSFLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGASWTR 68
Query 50 GDQPHSSVREQFLLLGRNSNRVQ---------------------AVVQSSVSSDHERRQI 88
+ P ++ E L N V+ A + S + R +
Sbjct 69 KNWPIAANGELISALDGNWAEVEKHVTDKLKGKAAKGEAKGATGAALTSEEITQAARDSV 128
Query 89 GVLQLIAAYRNRGHQKAKLDPLGLAKR-EDVPDLDLSAHGLTKSDLDTVFNTSNLAIGKA 147
+ +I AYR RGH A LDPLGL+++ D +L+ +G T +D + N+ +G
Sbjct 129 RAIMMIRAYRMRGHLHANLDPLGLSEKPNDYNELEPENYGFTPADYNRKIFIDNV-LGLE 187
Query 148 EATLGEMVETMESIYCGSIGAEYMHIVDTKEKRWIQQRLEGARGQFNFTNDQKKALLERL 207
AT+ EM++ ++ YCG+IG E+MHI D EK WIQ+R+EG + FT + KKA+L +L
Sbjct 188 YATVPEMLDILKRTYCGTIGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKKAILSKL 247
Query 208 TAAEGLEKFLGNKYVGAKRFGVEGGESFIPMMNEIIQRAGSVGCKEVVIGMPHRGRLNLL 267
AEG E+F+ KY G KRFG++GGES IP + +I++R G++G KE++ GM HRGRLN+L
Sbjct 248 IEAEGFEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGAMGVKEIIFGMAHRGRLNVL 307
Query 268 VNIMGKNPADLFGEFEGKSIHK---KGSGDVKYHQGFSSNVMTPGGEVHLALAFNPSHLE 324
+MGK +F EF+G S +GSGDVKYH G SS+ G +VHL+L NPSHLE
Sbjct 308 SQVMGKPHRAIFHEFKGGSYAPDDVEGSGDVKYHLGASSDREFDGNKVHLSLTANPSHLE 367
Query 325 IVGPVVEGSVRARQVRRKDIGGDD---------VLPVIVHGDAAFAGQGVNQETFQMSQT 375
IV PVV G RA+Q DD VLP+++HGDAAFAGQGV E +S
Sbjct 368 IVNPVVMGKARAKQDLLAGRTRDDMVPLATRAKVLPLLLHGDAAFAGQGVVAECLGLSGL 427
Query 376 RGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMVQSPIFHVNGDDPEAVAFIAQ 435
+G+ V GT+H +INNQ+GFTT+ P +RS+ Y +DVAKM+++PIFHVNGDDPEAV F A+
Sbjct 428 KGHRVAGTLHFIINNQIGFTTN-PAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVFAAK 486
Query 436 LAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQVINKKPTTRTLYADQLVQQK 495
+A +FR TF K VVID+FCYRR GHNE DEPS TQPLMY+ I TT LY+D+L+ +
Sbjct 487 VATEFRMTFHKPVVIDMFCYRRFGHNEGDEPSFTQPLMYKAIRAHKTTVQLYSDKLIAEG 546
Query 496 VLDRAEADKLIEDYRSDLEAGNHVANALVLEPNTKMFVD--WKPYLGHDYTDVW---DTT 550
++ + E D++ +R +LE + +PN ++D W D D T
Sbjct 547 LIKQEEIDQMKAQWRENLETEFDAGQSY--KPNKADWLDGAWAGLRTADNADEQRRGKTA 604
Query 551 IDINRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKM-QTGEMPLNWGAAETLAYATLIDE 609
+ + LKE+G+ + ++P+ F + R + + +D+R KM +TGE ++W AE+LA+ +L+ E
Sbjct 605 VPMKTLKEIGKKLVEVPKDFHVHRTIQRFLDNRAKMMETGE-GIDWATAESLAFGSLVAE 663
Query 610 GYLVRITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQPRFALYDSLLSEEAVLAF 669
G +R++G+DV RGTFS RH L++Q + YIPL ++++ Q + +S+LSEEAVL +
Sbjct 664 GSPIRLSGQDVERGTFSQRHTVLYDQETQNRYIPLNNIQKGQAIYEAINSMLSEEAVLGY 723
Query 670 EYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCGLTMLLPHGFEGQGP 729
EYGY+ + P +L++WEAQFGDFAN AQVV DQFI+SGE KW R+ GL LLPHG+EGQGP
Sbjct 724 EYGYSLSDPRALVLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGYEGQGP 783
Query 730 EHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLRHKLA 789
EHSSARLER+LQ+CAEDNMQV TTPA FH LRRQ R RKP+I+M+PKSLLRHK A
Sbjct 784 EHSSARLERWLQMCAEDNMQVANVTTPANYFHILRRQMKRDFRKPLIMMTPKSLLRHKRA 843
Query 790 TSTLEELA-TGTFQTVIDEVDQITKSD---------VTRLVLCGGKVYYDLIEKRRELEL 839
STL EL+ +F ++ + Q K + + R+VLC GKVYYDL E+R + +
Sbjct 844 VSTLNELSGESSFHRLLWDDAQYNKDEGIKLQKDAKIRRVVLCSGKVYYDLYEEREKRGI 903
Query 840 NNIAVVRIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILK-- 897
+++ ++R+EQLYP+P + L L+ + + ++VWCQEEPKN GAW FI P L + +L
Sbjct 904 DDVYLLRVEQLYPFPAKALINELSRFRHA-EMVWCQEEPKNMGAWSFIDPYL-EWVLAHI 961
Query 898 SGKQIRISYAGREASAAPACGSPYLHAKQQAQLIHDAL 935
K R+ YAGR A+A+PA G H Q A + DAL
Sbjct 962 DAKHQRVRYAGRPAAASPATGLMSKHLAQLAAFLEDAL 999
>A5VSQ0 2-oxoglutarate dehydrogenase E1 component [Brucella ovis
(strain ATCC 25840 / 63/290 / NCTC 10512)]
Length=1004
Score = 801 bits (2068), Expect = 0.0
Identities = 451/998 (45%), Positives = 620/998 (62%), Gaps = 75/998 (8%)
Query 6 DALRLDTELSADSAAYIEELYEQYLTSPTSVTEDWRQYFDK----------------FPK 49
D L + L +A YIEELY +Y P SV WR +F K + +
Sbjct 13 DVFALTSFLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGPSWTR 72
Query 50 GDQPHSSVREQFLLLGRNSNRVQAVVQSSVS---------------------SDHERRQI 88
+ P ++ E L N V+ V + + R +
Sbjct 73 KNWPIAANGELVSALDGNWAEVEKHVTDKLKGKAAKGEAKGAAGTPLTAEEITQAARDSV 132
Query 89 GVLQLIAAYRNRGHQKAKLDPLGLAKR-EDVPDLDLSAHGLTKSDLDTVFNTSNLAIGKA 147
+ +I AYR RGH A LDPLGLA++ D +L+ +G T +D + N+ +G
Sbjct 133 RAIMMIRAYRMRGHLHANLDPLGLAEKPNDYNELEPENYGFTPADYNRKIFIDNV-LGLE 191
Query 148 EATLGEMVETMESIYCGSIGAEYMHIVDTKEKRWIQQRLEGARGQFNFTNDQKKALLERL 207
AT+ EM++ ++ YCG+IG E+MHI D EK WIQ+R+EG + FT + K A+L +L
Sbjct 192 YATVPEMLDILKRTYCGAIGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKMAILSKL 251
Query 208 TAAEGLEKFLGNKYVGAKRFGVEGGESFIPMMNEIIQRAGSVGCKEVVIGMPHRGRLNLL 267
AEG E+F+ KY G KRFG++GGES IP + +I++R G +G KEVV+GM HRGRLN+L
Sbjct 252 IEAEGFEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGQMGLKEVVLGMAHRGRLNVL 311
Query 268 VNIMGKNPADLFGEFEGKSIHK---KGSGDVKYHQGFSSNVMTPGGEVHLALAFNPSHLE 324
+MGK +F EF+G S +GSGDVKYH G SS+ G +VHL+L NPSHLE
Sbjct 312 SQVMGKPHRAIFHEFKGGSYTPDDVEGSGDVKYHLGASSDREFDGNKVHLSLTANPSHLE 371
Query 325 IVGPVVEGSVRARQVRRKDIGGDD---------VLPVIVHGDAAFAGQGVNQETFQMSQT 375
IV PVV G RA+Q DD VLP+++HGDAAFAGQGV E +S
Sbjct 372 IVNPVVMGKARAKQDLLVGRTRDDMVPLSERAKVLPLLLHGDAAFAGQGVVAECLGLSGL 431
Query 376 RGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMVQSPIFHVNGDDPEAVAFIAQ 435
+G+ V GT+H +INNQ+GFTT+ P +RS+ Y +DVAKM+++PIFHVNGDDPEAV F A+
Sbjct 432 KGHRVAGTLHFIINNQIGFTTN-PAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVFAAK 490
Query 436 LAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQVINKKPTTRTLYADQLVQQK 495
+A +FR TF K VVID+FCYRR GHNE DEPS TQPLMY+ I TT LY ++L+ +
Sbjct 491 VATEFRMTFHKPVVIDMFCYRRFGHNEGDEPSFTQPLMYKAIRAHKTTVQLYGEKLIAEG 550
Query 496 VLDRAEADKLIEDYRSDLEAGNHVANALVLEPNTKMFVD--WKPYLGHDYTD---VWDTT 550
++ + + D++ D+R LE + +PN ++D W D D T
Sbjct 551 LVTQDDIDRMKADWRQKLEGEFEAGQSY--KPNKADWLDGAWAGLRTADNADEQRCGKTA 608
Query 551 IDINRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKM-QTGEMPLNWGAAETLAYATLIDE 609
+ + LKE+G+ + ++P+ F + R + + +D+R KM +TGE ++W AE+LA+ +L E
Sbjct 609 VPVKTLKEIGKKLVEVPKDFHVHRTIQRFLDNRAKMMETGE-GIDWATAESLAFGSLAVE 667
Query 610 GYLVRITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQPRFALYDSLLSEEAVLAF 669
G+ +R++G+DV RGTFS RH L++Q + + YIPL ++++ Q + +S+LSEEAVL +
Sbjct 668 GHPIRLSGQDVERGTFSQRHTVLYDQENQNRYIPLNNLQKGQAIYEAINSMLSEEAVLGY 727
Query 670 EYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCGLTMLLPHGFEGQGP 729
EYGY+ + P +L++WEAQFGDFAN AQVV DQFI+SGE KW R+ GL LLPHGFEGQGP
Sbjct 728 EYGYSLSDPRALVLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGFEGQGP 787
Query 730 EHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLRHKLA 789
EHSSARLER+LQLCAEDNMQV TTPA FH LRRQ R RKP+I+M+PKSLLRHK A
Sbjct 788 EHSSARLERYLQLCAEDNMQVANVTTPANYFHILRRQMKRDFRKPLIMMTPKSLLRHKRA 847
Query 790 TSTLEELA-TGTFQTVIDEVDQITKSD---------VTRLVLCGGKVYYDLIEKRRELEL 839
STL EL+ +F ++ + Q K + + R+VLC GKVYYDL E+R + +
Sbjct 848 ISTLAELSGESSFHRLLWDDAQYNKDEGIKLQKDAKIRRVVLCSGKVYYDLYEEREKRGI 907
Query 840 NNIAVVRIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILK-- 897
+++ ++R+EQLYP+P + L L+ + + ++VWCQEEPKN GAW FI P L + +L
Sbjct 908 DDVYLLRVEQLYPFPAKALINELSRFRHA-EMVWCQEEPKNMGAWSFIDPYL-EWVLAHI 965
Query 898 SGKQIRISYAGREASAAPACGSPYLHAKQQAQLIHDAL 935
K R+ YAGR A+A+PA G H Q A + DAL
Sbjct 966 DAKHQRVRYAGRPAAASPATGLMSKHLAQLAAFLEDAL 1003
>Q8YJE4 2-oxoglutarate dehydrogenase E1 component [Brucella melitensis
biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)]
Length=1004
Score = 800 bits (2067), Expect = 0.0
Identities = 451/998 (45%), Positives = 620/998 (62%), Gaps = 75/998 (8%)
Query 6 DALRLDTELSADSAAYIEELYEQYLTSPTSVTEDWRQYFDK----------------FPK 49
D L + L +A YIEELY +Y P SV WR +F K + +
Sbjct 13 DVFALTSFLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGPSWTR 72
Query 50 GDQPHSSVREQFLLLGRNSNRVQAVVQSSVS---------------------SDHERRQI 88
+ P ++ E L N V+ V + + R +
Sbjct 73 KNWPIAANGELVSALDGNWAEVEKHVTDKLKGKAAKGEAKGAAGTPLTAEEITQAARDSV 132
Query 89 GVLQLIAAYRNRGHQKAKLDPLGLAKR-EDVPDLDLSAHGLTKSDLDTVFNTSNLAIGKA 147
+ +I AYR RGH A LDPLGLA++ D +L+ +G T +D + N+ +G
Sbjct 133 RAIMMIRAYRMRGHLHANLDPLGLAEKPNDYNELEPENYGFTPADYNRKIFIDNV-LGLE 191
Query 148 EATLGEMVETMESIYCGSIGAEYMHIVDTKEKRWIQQRLEGARGQFNFTNDQKKALLERL 207
AT+ EM++ ++ YCG+IG E+MHI D EK WIQ+R+EG + FT + KKA+L +L
Sbjct 192 YATVPEMLDILKRTYCGAIGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKKAILSKL 251
Query 208 TAAEGLEKFLGNKYVGAKRFGVEGGESFIPMMNEIIQRAGSVGCKEVVIGMPHRGRLNLL 267
AEG E+F+ KY G KRFG++GGES IP + +I++R G +G KEVV+GM HRGRLN+L
Sbjct 252 IEAEGFEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGQMGLKEVVLGMAHRGRLNVL 311
Query 268 VNIMGKNPADLFGEFEGKSIHK---KGSGDVKYHQGFSSNVMTPGGEVHLALAFNPSHLE 324
+MGK +F EF+G S +GSGDVKYH G SS+ G +VHL+L NPSHLE
Sbjct 312 SQVMGKPHRAIFHEFKGGSYTPDDVEGSGDVKYHLGASSDREFDGNKVHLSLTANPSHLE 371
Query 325 IVGPVVEGSVRARQVRRKDIGGDD---------VLPVIVHGDAAFAGQGVNQETFQMSQT 375
IV PVV G RA+Q DD VLP+++HGDAAFAGQGV E +S
Sbjct 372 IVNPVVMGKARAKQDLLVGRTRDDMVPLSERAKVLPLLLHGDAAFAGQGVVAECLGLSGL 431
Query 376 RGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMVQSPIFHVNGDDPEAVAFIAQ 435
+G+ V GT+H +INNQ+GFTT+ P +RS+ Y +DVAKM+++PIFHVNGDDPEAV F A+
Sbjct 432 KGHRVAGTLHFIINNQIGFTTN-PAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVFAAK 490
Query 436 LAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQVINKKPTTRTLYADQLVQQK 495
+A +FR TF K VVID+FCYRR GHNE DEPS TQPLMY+ I TT LY ++L+ +
Sbjct 491 VATEFRMTFHKPVVIDMFCYRRFGHNEGDEPSFTQPLMYKAIRAHKTTVQLYGEKLIAEG 550
Query 496 VLDRAEADKLIEDYRSDLEAGNHVANALVLEPNTKMFVD--WKPYLGHDYTDVW---DTT 550
++ + + D++ D+R LE + +PN ++D W D D T
Sbjct 551 LVTQDDIDRMKADWRQKLEGEFEAGQSY--KPNKADWLDGAWAGLRTADNADEQRRGKTA 608
Query 551 IDINRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKM-QTGEMPLNWGAAETLAYATLIDE 609
+ + LKE+G+ + ++P+ F + R + + +D+R KM +TGE ++W AE+LA+ +L E
Sbjct 609 VPVKTLKEIGKKLVEVPKDFHVHRTIQRFLDNRAKMMETGE-GIDWATAESLAFGSLAVE 667
Query 610 GYLVRITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQPRFALYDSLLSEEAVLAF 669
+ +R++G+DV RGTFS RH L++Q + + YIPL ++++ Q + +S+LSEEAVL +
Sbjct 668 AHPIRLSGQDVERGTFSQRHTVLYDQENQNRYIPLNNLQKGQAIYEAINSMLSEEAVLGY 727
Query 670 EYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCGLTMLLPHGFEGQGP 729
EYGY+ + P +L++WEAQFGDFAN AQVV DQFI+SGE KW R+ GL LLPHGFEGQGP
Sbjct 728 EYGYSLSDPRALVLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGFEGQGP 787
Query 730 EHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLRHKLA 789
EHSSARLER+LQLCAEDNMQV TTPA FH LRRQ R RKP+I+M+PKSLLRHK A
Sbjct 788 EHSSARLERYLQLCAEDNMQVANVTTPANYFHILRRQMKRDFRKPLIMMTPKSLLRHKRA 847
Query 790 TSTLEELA-TGTFQTVIDEVDQITKSD---------VTRLVLCGGKVYYDLIEKRRELEL 839
STL EL+ +F ++ + Q K + + R+VLC GKVYYDL E+R + +
Sbjct 848 ISTLAELSGESSFHRLLWDDAQYNKDEGIKLQKDAKIRRVVLCSGKVYYDLYEEREKRGI 907
Query 840 NNIAVVRIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILK-- 897
+++ ++R+EQLYP+P + L L+ + + ++VWCQEEPKN GAW FI P L + +L
Sbjct 908 DDVYLLRVEQLYPFPAKALINELSRFRHA-EMVWCQEEPKNMGAWSFIDPYL-EWVLAHI 965
Query 898 SGKQIRISYAGREASAAPACGSPYLHAKQQAQLIHDAL 935
K R+ YAGR A+A+PA G H Q A + DAL
Sbjct 966 DAKHQRVRYAGRPAAASPATGLMSKHLAQLAAFLEDAL 1003
>C0RFG8 2-oxoglutarate dehydrogenase E1 component [Brucella melitensis
biotype 2 (strain ATCC 23457)]
Length=1004
Score = 800 bits (2067), Expect = 0.0
Identities = 451/998 (45%), Positives = 620/998 (62%), Gaps = 75/998 (8%)
Query 6 DALRLDTELSADSAAYIEELYEQYLTSPTSVTEDWRQYFDK----------------FPK 49
D L + L +A YIEELY +Y P SV WR +F K + +
Sbjct 13 DVFALTSFLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGPSWTR 72
Query 50 GDQPHSSVREQFLLLGRNSNRVQAVVQSSVS---------------------SDHERRQI 88
+ P ++ E L N V+ V + + R +
Sbjct 73 KNWPIAANGELVSALDGNWAEVEKHVTDKLKGKAAKGEAKGAAGTPLTAEEITQAARDSV 132
Query 89 GVLQLIAAYRNRGHQKAKLDPLGLAKR-EDVPDLDLSAHGLTKSDLDTVFNTSNLAIGKA 147
+ +I AYR RGH A LDPLGLA++ D +L+ +G T +D + N+ +G
Sbjct 133 RAIMMIRAYRMRGHLHANLDPLGLAEKPNDYNELEPENYGFTPADYNRKIFIDNV-LGLE 191
Query 148 EATLGEMVETMESIYCGSIGAEYMHIVDTKEKRWIQQRLEGARGQFNFTNDQKKALLERL 207
AT+ EM++ ++ YCG+IG E+MHI D EK WIQ+R+EG + FT + KKA+L +L
Sbjct 192 YATVPEMLDILKRTYCGAIGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKKAILSKL 251
Query 208 TAAEGLEKFLGNKYVGAKRFGVEGGESFIPMMNEIIQRAGSVGCKEVVIGMPHRGRLNLL 267
AEG E+F+ KY G KRFG++GGES IP + +I++R G +G KEVV+GM HRGRLN+L
Sbjct 252 IEAEGFEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGQMGLKEVVLGMAHRGRLNVL 311
Query 268 VNIMGKNPADLFGEFEGKSIHK---KGSGDVKYHQGFSSNVMTPGGEVHLALAFNPSHLE 324
+MGK +F EF+G S +GSGDVKYH G SS+ G +VHL+L NPSHLE
Sbjct 312 SQVMGKPHRAIFHEFKGGSYTPDDVEGSGDVKYHLGASSDREFDGNKVHLSLTANPSHLE 371
Query 325 IVGPVVEGSVRARQVRRKDIGGDD---------VLPVIVHGDAAFAGQGVNQETFQMSQT 375
IV PVV G RA+Q DD VLP+++HGDAAFAGQGV E +S
Sbjct 372 IVNPVVMGKARAKQDLLVGRTRDDMVPLSERAKVLPLLLHGDAAFAGQGVVAECLGLSGL 431
Query 376 RGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMVQSPIFHVNGDDPEAVAFIAQ 435
+G+ V GT+H +INNQ+GFTT+ P +RS+ Y +DVAKM+++PIFHVNGDDPEAV F A+
Sbjct 432 KGHRVAGTLHFIINNQIGFTTN-PAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVFAAK 490
Query 436 LAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQVINKKPTTRTLYADQLVQQK 495
+A +FR TF K VVID+FCYRR GHNE DEPS TQPLMY+ I TT LY ++L+ +
Sbjct 491 VATEFRMTFHKPVVIDMFCYRRFGHNEGDEPSFTQPLMYKAIRAHKTTVQLYGEKLIAEG 550
Query 496 VLDRAEADKLIEDYRSDLEAGNHVANALVLEPNTKMFVD--WKPYLGHDYTDVW---DTT 550
++ + + D++ D+R LE + +PN ++D W D D T
Sbjct 551 LVTQDDIDRMKADWRQKLEGEFEAGQSY--KPNKADWLDGAWAGLRTADNADEQRRGKTA 608
Query 551 IDINRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKM-QTGEMPLNWGAAETLAYATLIDE 609
+ + LKE+G+ + ++P+ F + R + + +D+R KM +TGE ++W AE+LA+ +L E
Sbjct 609 VPVKTLKEIGKKLVEVPKDFHVHRTIQRFLDNRAKMMETGE-GIDWATAESLAFGSLAVE 667
Query 610 GYLVRITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQPRFALYDSLLSEEAVLAF 669
+ +R++G+DV RGTFS RH L++Q + + YIPL ++++ Q + +S+LSEEAVL +
Sbjct 668 AHPIRLSGQDVERGTFSQRHTVLYDQENQNRYIPLNNLQKGQAIYEAINSMLSEEAVLGY 727
Query 670 EYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCGLTMLLPHGFEGQGP 729
EYGY+ + P +L++WEAQFGDFAN AQVV DQFI+SGE KW R+ GL LLPHGFEGQGP
Sbjct 728 EYGYSLSDPRALVLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGFEGQGP 787
Query 730 EHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLRHKLA 789
EHSSARLER+LQLCAEDNMQV TTPA FH LRRQ R RKP+I+M+PKSLLRHK A
Sbjct 788 EHSSARLERYLQLCAEDNMQVANVTTPANYFHILRRQMKRDFRKPLIMMTPKSLLRHKRA 847
Query 790 TSTLEELA-TGTFQTVIDEVDQITKSD---------VTRLVLCGGKVYYDLIEKRRELEL 839
STL EL+ +F ++ + Q K + + R+VLC GKVYYDL E+R + +
Sbjct 848 ISTLAELSGESSFHRLLWDDAQYNKDEGIKLQKDAKIRRVVLCSGKVYYDLYEEREKRGI 907
Query 840 NNIAVVRIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILK-- 897
+++ ++R+EQLYP+P + L L+ + + ++VWCQEEPKN GAW FI P L + +L
Sbjct 908 DDVYLLRVEQLYPFPAKALINELSRFRHA-EMVWCQEEPKNMGAWSFIDPYL-EWVLAHI 965
Query 898 SGKQIRISYAGREASAAPACGSPYLHAKQQAQLIHDAL 935
K R+ YAGR A+A+PA G H Q A + DAL
Sbjct 966 DAKHQRVRYAGRPAAASPATGLMSKHLAQLAAFLEDAL 1003
>Q57AX5 2-oxoglutarate dehydrogenase E1 component [Brucella abortus
biovar 1 (strain 9-941)]
Length=1004
Score = 800 bits (2067), Expect = 0.0
Identities = 451/998 (45%), Positives = 621/998 (62%), Gaps = 75/998 (8%)
Query 6 DALRLDTELSADSAAYIEELYEQYLTSPTSVTEDWRQYFDK----------------FPK 49
D L + L +A YIEELY +Y P SV WR +F K + +
Sbjct 13 DVFALTSFLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGPSWTR 72
Query 50 GDQPHSSVREQFLLLGRNSNRVQAVVQSSVS---------------------SDHERRQI 88
+ P ++ E L N V+ V + + R +
Sbjct 73 KNWPIAANGELVSALDGNWAEVEKHVTDKLKGKAAKGEAKGAAGTPLTAEEITQAARDSV 132
Query 89 GVLQLIAAYRNRGHQKAKLDPLGLAKR-EDVPDLDLSAHGLTKSDLDTVFNTSNLAIGKA 147
+ +I AYR RGH A LDPLGLA++ D +L+ +G T +D + N+ +G
Sbjct 133 RAIMMIRAYRMRGHLHANLDPLGLAEKPNDYNELEPENYGFTPADYNRKIFIDNV-LGLE 191
Query 148 EATLGEMVETMESIYCGSIGAEYMHIVDTKEKRWIQQRLEGARGQFNFTNDQKKALLERL 207
AT+ EM++ ++ YCG+IG E+MHI D EK WIQ+R+EG + FT + KKA+L +L
Sbjct 192 YATVPEMLDILKRTYCGAIGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKKAILSKL 251
Query 208 TAAEGLEKFLGNKYVGAKRFGVEGGESFIPMMNEIIQRAGSVGCKEVVIGMPHRGRLNLL 267
AEG E+F+ KY G KRFG++GGES IP + +I++R G +G KEVV+GM HRGRLN+L
Sbjct 252 IEAEGFEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGQMGLKEVVLGMAHRGRLNVL 311
Query 268 VNIMGKNPADLFGEFEGKSIHK---KGSGDVKYHQGFSSNVMTPGGEVHLALAFNPSHLE 324
+MGK +F EF+G S +GSGDVKYH G SS+ G +VHL+L NPSHLE
Sbjct 312 SQVMGKPHRAIFHEFKGGSYTPDDVEGSGDVKYHLGASSDREFDGNKVHLSLTANPSHLE 371
Query 325 IVGPVVEGSVRARQVRRKDIGGDD---------VLPVIVHGDAAFAGQGVNQETFQMSQT 375
IV PVV G RA+Q DD VLP+++HGDAAFAGQGV E +S
Sbjct 372 IVNPVVMGKARAKQDLLVGRTRDDMVPLSERAKVLPLLLHGDAAFAGQGVVAECLGLSGL 431
Query 376 RGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMVQSPIFHVNGDDPEAVAFIAQ 435
+G+ V GT+H +INNQ+GFTT+ P +RS+ Y +DVAKM+++PIFHVNGDDPEAV F A+
Sbjct 432 KGHRVAGTLHFIINNQIGFTTN-PAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVFAAK 490
Query 436 LAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQVINKKPTTRTLYADQLVQQK 495
+A +FR TF K VVID+FCYRR GHNE DEPS TQPLMY+ I TT LY ++L+ +
Sbjct 491 VATEFRMTFHKPVVIDMFCYRRFGHNEGDEPSFTQPLMYKAIRAHKTTVQLYGEKLIAEG 550
Query 496 VLDRAEADKLIEDYRSDLEAGNHVANALVLEPNTKMFVD--WKPYLGHDYTDVW---DTT 550
++ + + D++ D+R LE + +PN ++D W D D T
Sbjct 551 LVTQDDIDRMKADWRQKLEGEFEAGQSY--KPNKADWLDGAWAGLRTADNADEQRRGKTA 608
Query 551 IDINRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKM-QTGEMPLNWGAAETLAYATLIDE 609
+ + LKE+G+ + ++P+ F + R + + +D+R KM +TGE ++W AE+LA+ +L E
Sbjct 609 VPVKTLKEIGKKLVEVPKDFHVHRTIQRFLDNRAKMMETGE-GIDWATAESLAFGSLAVE 667
Query 610 GYLVRITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQPRFALYDSLLSEEAVLAF 669
G+ +R++G+DV RGTFS RH L++Q + + YIPL ++++ Q + +S+LSEEAVL +
Sbjct 668 GHPIRLSGQDVERGTFSQRHTVLYDQENQNRYIPLNNLQKGQAIYEAINSMLSEEAVLGY 727
Query 670 EYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCGLTMLLPHGFEGQGP 729
EYGY+ + P +L++WEAQFGDFAN AQVV DQFI+SGE KW R+ GL LLPHGFEGQGP
Sbjct 728 EYGYSLSDPRALVLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGFEGQGP 787
Query 730 EHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLRHKLA 789
EHSSARLER+LQLCAEDNMQV TTPA FH LRRQ R RKP+I+M+PKSLLRHK A
Sbjct 788 EHSSARLERYLQLCAEDNMQVANVTTPANYFHILRRQMKRDFRKPLIMMTPKSLLRHKRA 847
Query 790 TSTLEELA-TGTFQTVIDEVDQITK---------SDVTRLVLCGGKVYYDLIEKRRELEL 839
STL EL+ +F ++ + + K + + R+VLC GKVYYDL E+R + +
Sbjct 848 ISTLAELSGESSFHRLLWDDARYNKDKGIKLQKDAKIRRVVLCSGKVYYDLYEEREKRGI 907
Query 840 NNIAVVRIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILK-- 897
+++ ++R+EQLYP+P + L L+ + + ++VWCQEEPKN GAW FI P L + +L
Sbjct 908 DDVYLLRVEQLYPFPAKALINELSRFRHA-EMVWCQEEPKNMGAWSFIDPYL-EWVLAHI 965
Query 898 SGKQIRISYAGREASAAPACGSPYLHAKQQAQLIHDAL 935
K R+ YAGR A+A+PA G H Q A + DAL
Sbjct 966 DAKHQRVRYAGRPAAASPATGLMSKHLAQLAAFLEDAL 1003
>Q2YLS2 2-oxoglutarate dehydrogenase E1 component [Brucella abortus
(strain 2308)]
Length=1004
Score = 800 bits (2067), Expect = 0.0
Identities = 451/998 (45%), Positives = 621/998 (62%), Gaps = 75/998 (8%)
Query 6 DALRLDTELSADSAAYIEELYEQYLTSPTSVTEDWRQYFDK----------------FPK 49
D L + L +A YIEELY +Y P SV WR +F K + +
Sbjct 13 DVFALTSFLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGPSWTR 72
Query 50 GDQPHSSVREQFLLLGRNSNRVQAVVQSSVS---------------------SDHERRQI 88
+ P ++ E L N V+ V + + R +
Sbjct 73 KNWPIAANGELVSALDGNWAEVEKHVTDKLKGKAAKGEAKGAAGTPLTAEEITQAARDSV 132
Query 89 GVLQLIAAYRNRGHQKAKLDPLGLAKR-EDVPDLDLSAHGLTKSDLDTVFNTSNLAIGKA 147
+ +I AYR RGH A LDPLGLA++ D +L+ +G T +D + N+ +G
Sbjct 133 RAIMMIRAYRMRGHLHANLDPLGLAEKPNDYNELEPENYGFTPADYNRKIFIDNV-LGLE 191
Query 148 EATLGEMVETMESIYCGSIGAEYMHIVDTKEKRWIQQRLEGARGQFNFTNDQKKALLERL 207
AT+ EM++ ++ YCG+IG E+MHI D EK WIQ+R+EG + FT + KKA+L +L
Sbjct 192 YATVPEMLDILKRTYCGAIGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKKAILSKL 251
Query 208 TAAEGLEKFLGNKYVGAKRFGVEGGESFIPMMNEIIQRAGSVGCKEVVIGMPHRGRLNLL 267
AEG E+F+ KY G KRFG++GGES IP + +I++R G +G KEVV+GM HRGRLN+L
Sbjct 252 IEAEGFEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGQMGLKEVVLGMAHRGRLNVL 311
Query 268 VNIMGKNPADLFGEFEGKSIHK---KGSGDVKYHQGFSSNVMTPGGEVHLALAFNPSHLE 324
+MGK +F EF+G S +GSGDVKYH G SS+ G +VHL+L NPSHLE
Sbjct 312 SQVMGKPHRAIFHEFKGGSYTPDDVEGSGDVKYHLGASSDREFDGNKVHLSLTANPSHLE 371
Query 325 IVGPVVEGSVRARQVRRKDIGGDD---------VLPVIVHGDAAFAGQGVNQETFQMSQT 375
IV PVV G RA+Q DD VLP+++HGDAAFAGQGV E +S
Sbjct 372 IVNPVVMGKARAKQDLLVGRTRDDMVPLSERAKVLPLLLHGDAAFAGQGVVAECLGLSGL 431
Query 376 RGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMVQSPIFHVNGDDPEAVAFIAQ 435
+G+ V GT+H +INNQ+GFTT+ P +RS+ Y +DVAKM+++PIFHVNGDDPEAV F A+
Sbjct 432 KGHRVAGTLHFIINNQIGFTTN-PAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVFAAK 490
Query 436 LAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQVINKKPTTRTLYADQLVQQK 495
+A +FR TF K VVID+FCYRR GHNE DEPS TQPLMY+ I TT LY ++L+ +
Sbjct 491 VATEFRMTFHKPVVIDMFCYRRFGHNEGDEPSFTQPLMYKAIRAHKTTVQLYGEKLIAEG 550
Query 496 VLDRAEADKLIEDYRSDLEAGNHVANALVLEPNTKMFVD--WKPYLGHDYTDVW---DTT 550
++ + + D++ D+R LE + +PN ++D W D D T
Sbjct 551 LVTQDDIDRMKADWRQKLEGEFEAGQSY--KPNKADWLDGAWAGLRTADNADEQRRGKTA 608
Query 551 IDINRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKM-QTGEMPLNWGAAETLAYATLIDE 609
+ + LKE+G+ + ++P+ F + R + + +D+R KM +TGE ++W AE+LA+ +L E
Sbjct 609 VPVKTLKEIGKKLVEVPKDFHVHRTIQRFLDNRAKMMETGE-GIDWATAESLAFGSLAVE 667
Query 610 GYLVRITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQPRFALYDSLLSEEAVLAF 669
G+ +R++G+DV RGTFS RH L++Q + + YIPL ++++ Q + +S+LSEEAVL +
Sbjct 668 GHPIRLSGQDVERGTFSQRHTVLYDQENQNRYIPLNNLQKGQAIYEAINSMLSEEAVLGY 727
Query 670 EYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCGLTMLLPHGFEGQGP 729
EYGY+ + P +L++WEAQFGDFAN AQVV DQFI+SGE KW R+ GL LLPHGFEGQGP
Sbjct 728 EYGYSLSDPRALVLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGFEGQGP 787
Query 730 EHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLRHKLA 789
EHSSARLER+LQLCAEDNMQV TTPA FH LRRQ R RKP+I+M+PKSLLRHK A
Sbjct 788 EHSSARLERYLQLCAEDNMQVANVTTPANYFHILRRQMKRDFRKPLIMMTPKSLLRHKRA 847
Query 790 TSTLEELA-TGTFQTVIDEVDQITK---------SDVTRLVLCGGKVYYDLIEKRRELEL 839
STL EL+ +F ++ + + K + + R+VLC GKVYYDL E+R + +
Sbjct 848 ISTLAELSGESSFHRLLWDDARYNKDKGIKLQKDAKIRRVVLCSGKVYYDLYEEREKRGI 907
Query 840 NNIAVVRIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILK-- 897
+++ ++R+EQLYP+P + L L+ + + ++VWCQEEPKN GAW FI P L + +L
Sbjct 908 DDVYLLRVEQLYPFPAKALINELSRFRHA-EMVWCQEEPKNMGAWSFIDPYL-EWVLAHI 965
Query 898 SGKQIRISYAGREASAAPACGSPYLHAKQQAQLIHDAL 935
K R+ YAGR A+A+PA G H Q A + DAL
Sbjct 966 DAKHQRVRYAGRPAAASPATGLMSKHLAQLAAFLEDAL 1003
>B2S877 2-oxoglutarate dehydrogenase E1 component [Brucella abortus
(strain S19)]
Length=1004
Score = 800 bits (2067), Expect = 0.0
Identities = 451/998 (45%), Positives = 621/998 (62%), Gaps = 75/998 (8%)
Query 6 DALRLDTELSADSAAYIEELYEQYLTSPTSVTEDWRQYFDK----------------FPK 49
D L + L +A YIEELY +Y P SV WR +F K + +
Sbjct 13 DVFALTSFLYGGNADYIEELYAKYEDDPNSVDPQWRDFFAKLGDNADDVKKNAEGPSWTR 72
Query 50 GDQPHSSVREQFLLLGRNSNRVQAVVQSSVS---------------------SDHERRQI 88
+ P ++ E L N V+ V + + R +
Sbjct 73 KNWPIAANGELVSALDGNWAEVEKHVTDKLKGKAAKGEAKGAAGTPLTAEEITQAARDSV 132
Query 89 GVLQLIAAYRNRGHQKAKLDPLGLAKR-EDVPDLDLSAHGLTKSDLDTVFNTSNLAIGKA 147
+ +I AYR RGH A LDPLGLA++ D +L+ +G T +D + N+ +G
Sbjct 133 RAIMMIRAYRMRGHLHANLDPLGLAEKPNDYNELEPENYGFTPADYNRKIFIDNV-LGLE 191
Query 148 EATLGEMVETMESIYCGSIGAEYMHIVDTKEKRWIQQRLEGARGQFNFTNDQKKALLERL 207
AT+ EM++ ++ YCG+IG E+MHI D EK WIQ+R+EG + FT + KKA+L +L
Sbjct 192 YATVPEMLDILKRTYCGAIGVEFMHISDPAEKAWIQERIEGPDKKVAFTPEGKKAILSKL 251
Query 208 TAAEGLEKFLGNKYVGAKRFGVEGGESFIPMMNEIIQRAGSVGCKEVVIGMPHRGRLNLL 267
AEG E+F+ KY G KRFG++GGES IP + +I++R G +G KEVV+GM HRGRLN+L
Sbjct 252 IEAEGFEQFIDVKYKGTKRFGLDGGESLIPALEQIVKRGGQMGLKEVVLGMAHRGRLNVL 311
Query 268 VNIMGKNPADLFGEFEGKSIHK---KGSGDVKYHQGFSSNVMTPGGEVHLALAFNPSHLE 324
+MGK +F EF+G S +GSGDVKYH G SS+ G +VHL+L NPSHLE
Sbjct 312 SQVMGKPHRAIFHEFKGGSYTPDDVEGSGDVKYHLGASSDREFDGNKVHLSLTANPSHLE 371
Query 325 IVGPVVEGSVRARQVRRKDIGGDD---------VLPVIVHGDAAFAGQGVNQETFQMSQT 375
IV PVV G RA+Q DD VLP+++HGDAAFAGQGV E +S
Sbjct 372 IVNPVVMGKARAKQDLLVGRTRDDMVPLSERAKVLPLLLHGDAAFAGQGVVAECLGLSGL 431
Query 376 RGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMVQSPIFHVNGDDPEAVAFIAQ 435
+G+ V GT+H +INNQ+GFTT+ P +RS+ Y +DVAKM+++PIFHVNGDDPEAV F A+
Sbjct 432 KGHRVAGTLHFIINNQIGFTTN-PAFSRSSPYPSDVAKMIEAPIFHVNGDDPEAVVFAAK 490
Query 436 LAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQVINKKPTTRTLYADQLVQQK 495
+A +FR TF K VVID+FCYRR GHNE DEPS TQPLMY+ I TT LY ++L+ +
Sbjct 491 VATEFRMTFHKPVVIDMFCYRRFGHNEGDEPSFTQPLMYKAIRAHKTTVQLYGEKLIAEG 550
Query 496 VLDRAEADKLIEDYRSDLEAGNHVANALVLEPNTKMFVD--WKPYLGHDYTDVW---DTT 550
++ + + D++ D+R LE + +PN ++D W D D T
Sbjct 551 LVTQDDIDRMKADWRQKLEGEFEAGQSY--KPNKADWLDGAWAGLRTADNADEQRRGKTA 608
Query 551 IDINRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKM-QTGEMPLNWGAAETLAYATLIDE 609
+ + LKE+G+ + ++P+ F + R + + +D+R KM +TGE ++W AE+LA+ +L E
Sbjct 609 VPVKTLKEIGKKLVEVPKDFHVHRTIQRFLDNRAKMMETGE-GIDWATAESLAFGSLAVE 667
Query 610 GYLVRITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQPRFALYDSLLSEEAVLAF 669
G+ +R++G+DV RGTFS RH L++Q + + YIPL ++++ Q + +S+LSEEAVL +
Sbjct 668 GHPIRLSGQDVERGTFSQRHTVLYDQENQNRYIPLNNLQKGQAIYEAINSMLSEEAVLGY 727
Query 670 EYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCGLTMLLPHGFEGQGP 729
EYGY+ + P +L++WEAQFGDFAN AQVV DQFI+SGE KW R+ GL LLPHGFEGQGP
Sbjct 728 EYGYSLSDPRALVLWEAQFGDFANGAQVVFDQFISSGERKWLRMSGLVCLLPHGFEGQGP 787
Query 730 EHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLRHKLA 789
EHSSARLER+LQLCAEDNMQV TTPA FH LRRQ R RKP+I+M+PKSLLRHK A
Sbjct 788 EHSSARLERYLQLCAEDNMQVANVTTPANYFHILRRQMKRDFRKPLIMMTPKSLLRHKRA 847
Query 790 TSTLEELA-TGTFQTVIDEVDQITK---------SDVTRLVLCGGKVYYDLIEKRRELEL 839
STL EL+ +F ++ + + K + + R+VLC GKVYYDL E+R + +
Sbjct 848 ISTLAELSGESSFHRLLWDDARYNKDKGIKLQKDAKIRRVVLCSGKVYYDLYEEREKRGI 907
Query 840 NNIAVVRIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILK-- 897
+++ ++R+EQLYP+P + L L+ + + ++VWCQEEPKN GAW FI P L + +L
Sbjct 908 DDVYLLRVEQLYPFPAKALINELSRFRHA-EMVWCQEEPKNMGAWSFIDPYL-EWVLAHI 965
Query 898 SGKQIRISYAGREASAAPACGSPYLHAKQQAQLIHDAL 935
K R+ YAGR A+A+PA G H Q A + DAL
Sbjct 966 DAKHQRVRYAGRPAAASPATGLMSKHLAQLAAFLEDAL 1003
>A0R2B1 2-oxoglutarate dehydrogenase E1 component / Dihydrolipoyllysine-residue
succinyltransferase component of 2-oxoglutarate
dehydrogenase complex [Mycolicibacterium smegmatis (strain
ATCC 700084 / mc(2)155)]
Length=1227
Score = 723 bits (1866), Expect = 0.0
Identities = 395/878 (45%), Positives = 552/878 (63%), Gaps = 43/878 (5%)
Query 84 ERRQIGVLQLIAAYRNRGHQKAKLDPLGL--AKREDVPDLDLSAHGLTKSDLDTVFNTSN 141
E + V++LIAAYRNRGH A +DPL L + PDLD+++HGLT DLD F
Sbjct 364 EDKNARVIELIAAYRNRGHLMADIDPLRLDNTRFRSHPDLDVNSHGLTLWDLDREFKVDG 423
Query 142 LAIGKAEATLGEMVETMESIYCGSIGAEYMHIVDTKEKRWIQQRLEGARGQFNFTNDQKK 201
A G L +++ + YC +G EY HI++ +++RWIQ+R+E + T ++K
Sbjct 424 FA-GVQRKKLRDILSVLRDAYCRHVGVEYTHILEPEQQRWIQERVETKHDKP--TVAEQK 480
Query 202 ALLERLTAAEGLEKFLGNKYVGAKRFGVEGGESFIPMMNEIIQRAGSVGCKEVVIGMPHR 261
+L +L AAE E FL KYVG KRF +EG E+ IPMM+ +I + G EVVI MPHR
Sbjct 481 YILSKLNAAEAFETFLQTKYVGQKRFSLEGAETVIPMMDAVIDQCAEHGLDEVVIAMPHR 540
Query 262 GRLNLLVNIMGKNPADLFGEFEGK--SIHKKGSGDVKYHQGFSSNVMTPGGE--VHLALA 317
GRLN+L NI+GK + +F EFEG GSGDVKYH G + + G+ + ++L
Sbjct 541 GRLNVLANIVGKPYSQIFSEFEGNLNPSQAHGSGDVKYHLGATGTYIQMFGDNDIEVSLT 600
Query 318 FNPSHLEIVGPVVEGSVRARQ--VRRKDIGGDD---VLPVIVHGDAAFAGQGVNQETFQM 372
NPSHLE V PV+EG VRA+Q + + G D+ V+P+++HGDAAFAGQGV ET +
Sbjct 601 ANPSHLEAVDPVLEGLVRAKQDLLDTGEEGSDNRFSVVPLMLHGDAAFAGQGVVAETLNL 660
Query 373 SQTRGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMVQSPIFHVNGDDPEAVAF 432
+ RGY GGT+HIV+NNQ+GFTT+ P D+RS+EYCTDVAKM+ +PIFHVNGDDPEA A+
Sbjct 661 ALLRGYRTGGTIHIVVNNQIGFTTA-PTDSRSSEYCTDVAKMIGAPIFHVNGDDPEACAW 719
Query 433 IAQLAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQVINKKPTTRTLYADQLV 492
+A+LA DFR F+KDVVID+ CYRRRGHNE D+PS TQP MY VI+ K +R Y + L+
Sbjct 720 VARLAVDFRQAFKKDVVIDMLCYRRRGHNEGDDPSMTQPYMYDVIDTKRGSRKAYTEALI 779
Query 493 QQKVLDRAEADKLIEDYRSDLEAGNHVANALV---LEPNTKMFVDWKPYLGHDYTDVWDT 549
+ + EA+ + DY+ LE + L +EP+ + D T
Sbjct 780 GRGDISMKEAEDALRDYQGQLERVFNEVRELEKHEIEPSESVEAD------QQIPSKLAT 833
Query 550 TIDINRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKMQTGEMPLNWGAAETLAYATLIDE 609
+D L+ +G+ LPEGF + +V V++ R +M E ++W AE LA +LI E
Sbjct 834 AVDKAMLQRIGDAHLALPEGFTVHPRVRPVLEKRREMAY-EGRIDWAFAELLALGSLIAE 892
Query 610 GYLVRITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQP------RFALYDSLLSE 663
G LVR++G+D RGTF+ RHA + ++ G + PL + N +F +Y+S LSE
Sbjct 893 GKLVRLSGQDTQRGTFTQRHAVIVDRKTGEEFTPLQLLATNPDGTPTGGKFLVYNSALSE 952
Query 664 EAVLAFEYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCGLTMLLPHG 723
A + FEYGY+ P+++++WEAQFGDF N AQ +ID+FI+SGE KW ++ + +LLPHG
Sbjct 953 FAAVGFEYGYSVGNPDAMVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSDVVLLLPHG 1012
Query 724 FEGQGPEHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSL 783
EGQGP+H+S R+ERFLQL AE +M + P+TPA FH LRR I++P+IV +PKS+
Sbjct 1013 HEGQGPDHTSGRIERFLQLWAEGSMTIAMPSTPANYFHLLRRHGKDGIQRPLIVFTPKSM 1072
Query 784 LRHKLATSTLEELATGTFQTVIDEV----DQITKSDVTRLVLCGGKVYYDLIEKRRELEL 839
LR+K A S + + F++V++E + ++ VTRL+L GK+YY+L ++ +
Sbjct 1073 LRNKAAVSDIRDFTESKFRSVLEEPMYTDGEGDRNKVTRLLLTSGKIYYELAARKAKENR 1132
Query 840 NNIAVVRIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWL---FIAPRLYDDIL 896
++A+VRIEQL P P +RLAE L YPNVK+ W QEEP NQGAW P + D
Sbjct 1133 EDVAIVRIEQLAPLPRRRLAETLDRYPNVKEKFWVQEEPANQGAWPSFGLTLPEILPDHF 1192
Query 897 KSGKQIRISYAGREASAAPACGSPYLHAKQQAQLIHDA 934
K+I R A +AP+ GS +HA +Q +++ A
Sbjct 1193 TGLKRI-----SRRAMSAPSSGSSKVHAVEQQEILDTA 1225
Score = 25.0 bits (53), Expect = 0.58
Identities = 7/22 (32%), Positives = 14/22 (64%), Gaps = 0/22 (0%)
Query 22 IEELYEQYLTSPTSVTEDWRQY 43
+EE+Y ++ P+SV W ++
Sbjct 15 VEEMYRKFRDDPSSVDPSWHEF 36
>P9WIS5 2-oxoglutarate dehydrogenase E1 component / Dihydrolipoyllysine-residue
succinyltransferase component of 2-oxoglutarate
dehydrogenase complex [Mycobacterium tuberculosis (strain
ATCC 25618 / H37Rv)]
Length=1231
Score = 706 bits (1822), Expect = 0.0
Identities = 394/874 (45%), Positives = 543/874 (62%), Gaps = 45/874 (5%)
Query 90 VLQLIAAYRNRGHQKAKLDPLGL--AKREDVPDLDLSAHGLTKSDLDTVFNTSNLAIGKA 147
V+ LIAAYRNRGH A DPL L A+ PDL++ HGLT DLD VF A G
Sbjct 372 VMNLIAAYRNRGHLMADTDPLRLDKARFRSHPDLEVLTHGLTLWDLDRVFKVDGFA-GAQ 430
Query 148 EATLGEMVETMESIYCGSIGAEYMHIVDTKEKRWIQQRLEGARGQFNFTNDQKKALLERL 207
L +++ + YC IG EY HI+D ++K W++QR+E T Q+K +L +L
Sbjct 431 YKKLRDVLGLLRDAYCRHIGVEYAHILDPEQKEWLEQRVETKH--VKPTVAQQKYILSKL 488
Query 208 TAAEGLEKFLGNKYVGAKRFGVEGGESFIPMMNEIIQRAGSVGCKEVVIGMPHRGRLNLL 267
AAE E FL KYVG KRF +EG ES IPMM+ I + G EVVIGMPHRGRLN+L
Sbjct 489 NAAEAFETFLQTKYVGQKRFSLEGAESVIPMMDAAIDQCAEHGLDEVVIGMPHRGRLNVL 548
Query 268 VNIMGKNPADLFGEFEGK--SIHKKGSGDVKYHQGFSSNVMTPGGE--VHLALAFNPSHL 323
NI+GK + +F EFEG GSGDVKYH G + + G+ + ++L NPSHL
Sbjct 549 ANIVGKPYSQIFTEFEGNLNPSQAHGSGDVKYHLGATGLYLQMFGDNDIQVSLTANPSHL 608
Query 324 EIVGPVVEGSVRARQ--VRRKDIGGD-----DVLPVIVHGDAAFAGQGVNQETFQMSQTR 376
E V PV+EG VRA+Q + I D V+P+++HGDAAFAGQGV ET ++
Sbjct 609 EAVDPVLEGLVRAKQDLLDHGSIDSDGQRAFSVVPLMLHGDAAFAGQGVVAETLNLANLP 668
Query 377 GYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMVQSPIFHVNGDDPEAVAFIAQL 436
GY VGGT+HI++NNQ+GFTT+ P +RS+EYCTDVAKM+ +PIFHVNGDDPEA ++A+L
Sbjct 669 GYRVGGTIHIIVNNQIGFTTA-PEYSRSSEYCTDVAKMIGAPIFHVNGDDPEACVWVARL 727
Query 437 AHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQVINKKPTTRTLYADQLVQQKV 496
A DFR F+KDVVID+ CYRRRGHNE D+PS T P +Y V++ K R Y + L+ +
Sbjct 728 AVDFRQRFKKDVVIDMLCYRRRGHNEGDDPSMTNPYVYDVVDTKRGARKSYTEALIGRGD 787
Query 497 LDRAEADKLIEDYRSDLEAGNHVANALV---LEPNTKMFVDWKPYLGHDYTDVWDTTIDI 553
+ EA+ + DY+ LE + L ++P+ + D G T +D
Sbjct 788 ISMKEAEDALRDYQGQLERVFNEVRELEKHGVQPSESVESDQMIPAG------LATAVDK 841
Query 554 NRLKELGEGMRKLPEGFVMQRQVSKVIDDRLKMQTGEMPLNWGAAETLAYATLIDEGYLV 613
+ L +G+ LP GF +V V++ R +M E ++W E LA +L+ EG LV
Sbjct 842 SLLARIGDAFLALPNGFTAHPRVQPVLEKRREMAY-EGKIDWAFGELLALGSLVAEGKLV 900
Query 614 RITGEDVGRGTFSHRHAKLHNQVDGSTYIPLCHVKENQP------RFALYDSLLSEEAVL 667
R++G+D RGTFS RH+ L ++ G + PL + N +F +YDS LSE A +
Sbjct 901 RLSGQDSRRGTFSQRHSVLIDRHTGEEFTPLQLLATNSDGSPTGGKFLVYDSPLSEYAAV 960
Query 668 AFEYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCGLTMLLPHGFEGQ 727
FEYGY P+++++WEAQFGDF N AQ +ID+FI+SGE KW ++ + +LLPHG EGQ
Sbjct 961 GFEYGYTVGNPDAVVLWEAQFGDFVNGAQSIIDEFISSGEAKWGQLSNVVLLLPHGHEGQ 1020
Query 728 GPEHSSARLERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLRHK 787
GP+H+SAR+ERFLQL AE +M + P+TP+ FH LRR A+ I++P+IV +PKS+LRHK
Sbjct 1021 GPDHTSARIERFLQLWAEGSMTIAMPSTPSNYFHLLRRHALDGIQRPLIVFTPKSMLRHK 1080
Query 788 LATSTLEELATGTFQTVIDE---VDQI-TKSDVTRLVLCGGKVYYDLIEKRRELELNNIA 843
A S +++ F++V++E D I ++ V+R++L GK+YY+L ++ + N++A
Sbjct 1081 AAVSEIKDFTEIKFRSVLEEPTYEDGIGDRNKVSRILLTSGKLYYELAARKAKDNRNDLA 1140
Query 844 VVRIEQLYPYPEQRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIA---PRLYDDILKSGK 900
+VR+EQL P P +RL E L Y NVK+ W QEEP NQGAW P L D L K
Sbjct 1141 IVRLEQLAPLPRRRLRETLDRYENVKEFFWVQEEPANQGAWPRFGLELPELLPDKLAGIK 1200
Query 901 QIRISYAGREASAAPACGSPYLHAKQQAQLIHDA 934
+I R A +AP+ GS +HA +Q +++ +A
Sbjct 1201 RI-----SRRAMSAPSSGSSKVHAVEQQEILDEA 1229
Score = 25.0 bits (53), Expect = 0.58
Identities = 7/22 (32%), Positives = 14/22 (64%), Gaps = 0/22 (0%)
Query 22 IEELYEQYLTSPTSVTEDWRQY 43
+EE+Y ++ P+SV W ++
Sbjct 15 VEEMYRKFRDDPSSVDPSWHEF 36
>Q8NRC3 2-oxoglutarate dehydrogenase E1 component / Dihydrolipoyllysine-residue
succinyltransferase component of 2-oxoglutarate
dehydrogenase complex [Corynebacterium glutamicum (strain
ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730
/ NCIMB 10025)]
Length=1221
Score = 697 bits (1798), Expect = 0.0
Identities = 382/859 (44%), Positives = 531/859 (62%), Gaps = 26/859 (3%)
Query 90 VLQLIAAYRNRGHQKAKLDPLGLAKR----EDVPDLDLSAHGLTKSDLDTVFNTSNLAIG 145
V+QLI AYR+RGH A +PL + D DLD+ H LT DLD FN G
Sbjct 372 VMQLIEAYRSRGHLIADTNPLSWVQPGMPVPDHRDLDIETHNLTIWDLDRTFNVGGFG-G 430
Query 146 KAEATLGEMVETMESIYCGSIGAEYMHIVDTKEKRWIQQRLEGARGQFNFTNDQKKALLE 205
K TL E++ + + Y +G+EY HI+D E+ W+Q RLE G T ++K +L+
Sbjct 431 KETMTLREVLSRLRAAYTLKVGSEYTHILDRDERTWLQDRLEA--GMPKPTQAEQKYILQ 488
Query 206 RLTAAEGLEKFLGNKYVGAKRFGVEGGESFIPMMNEIIQRAGSVGCKEVVIGMPHRGRLN 265
+L AAE E FL KYVG KRF +EG E+ IP+M+ I A G EVVIGMPHRGRLN
Sbjct 489 KLNAAEAFENFLQTKYVGQKRFSLEGAEALIPLMDSAIDTAAGQGLDEVVIGMPHRGRLN 548
Query 266 LLVNIMGKNPADLFGEFEGKSIHKK--GSGDVKYHQGFSSN--VMTPGGEVHLALAFNPS 321
+L NI+GK A +F EFEG+ + GSGDVKYH G M GE+ ++L NPS
Sbjct 549 VLFNIVGKPLASIFNEFEGQMEQGQIGGSGDVKYHLGSEGQHLQMFGDGEIKVSLTANPS 608
Query 322 HLEIVGPVVEGSVRARQ-VRRKDIGGDDVLPVIVHGDAAFAGQGVNQETFQMSQTRGYTV 380
HLE V PV+EG VRA+Q K + G V+P+++HGDAAFAG G+ ET +++ RGY V
Sbjct 609 HLEAVNPVMEGIVRAKQDYLDKGVDGKTVVPLLLHGDAAFAGLGIVPETINLAKLRGYDV 668
Query 381 GGTVHIVINNQVGFTTSDPRDARSTEYCTDVAKMVQSPIFHVNGDDPEAVAFIAQLAHDF 440
GGT+HIV+NNQ+GFTT+ P +RS Y TD AK P+FHVNGDDPEAV ++ QLA ++
Sbjct 669 GGTIHIVVNNQIGFTTT-PDSSRSMHYATDYAKAFGCPVFHVNGDDPEAVVWVGQLATEY 727
Query 441 RHTFRKDVVIDLFCYRRRGHNEADEPSATQPLMYQVINKKPTTRTLYADQLVQQKVLDRA 500
R F KDV IDL CYR RGHNEAD+PS TQP MY++I + T R Y + L+ + L
Sbjct 728 RRRFGKDVFIDLVCYRLRGHNEADDPSMTQPKMYELITGRETVRAQYTEDLLGRGDLSNE 787
Query 501 EADKLIEDYRSDLEAG-NHVANALVLEPNTKMFVDWKPYLGHDYTDVWDTTIDINRLKEL 559
+A+ ++ D+ +E+ N V + + + L H +T I L EL
Sbjct 788 DAEAVVRDFHDQMESVFNEVKEGGKKQAEAQTGITGSQKLPHGL----ETNISREELLEL 843
Query 560 GEGMRKLPEGFVMQRQVSKVIDDRLKMQTGEMPLNWGAAETLAYATLIDEGYLVRITGED 619
G+ PEGF +V+ V R+ T E ++W E LA+ +L + G LVR+ GED
Sbjct 844 GQAFANTPEGFNYHPRVAPVAKKRVSSVT-EGGIDWAWGELLAFGSLANSGRLVRLAGED 902
Query 620 VGRGTFSHRHAKLHNQVDGSTYIPLCHV---KENQPRFALYDSLLSEEAVLAFEYGYATT 676
RGTF+ RHA + + PL + K N +F +Y+S L+E A + FEYGY+
Sbjct 903 SRRGTFTQRHAVAIDPATAEEFNPLHELAQSKGNNGKFLVYNSALTEYAGMGFEYGYSVG 962
Query 677 IPNSLIIWEAQFGDFANCAQVVIDQFIASGETKWERVCGLTMLLPHGFEGQGPEHSSARL 736
+S++ WEAQFGDFAN AQ +ID++++SGE KW + L +LLPHG+EGQGP+HSSAR+
Sbjct 963 NEDSIVAWEAQFGDFANGAQTIIDEYVSSGEAKWGQTSKLILLLPHGYEGQGPDHSSARI 1022
Query 737 ERFLQLCAEDNMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLRHKLATSTLEEL 796
ERFLQLCAE +M V P+TPA FH LRR A+ +++P+++ +PKS+LR+K A S E+
Sbjct 1023 ERFLQLCAEGSMTVAQPSTPANHFHLLRRHALSDLKRPLVIFTPKSMLRNKAAASAPEDF 1082
Query 797 ATGT-FQTVIDEVDQITKSDVTRLVLCGGKVYYDLIEKRRELELNNIAVVRIEQLYPYPE 855
T FQ+VI++ + + V +++L GK+YY+L +++ + ++IA+VRIE L+P P
Sbjct 1083 TEVTKFQSVINDPNVADAAKVKKVMLVSGKLYYELAKRKEKDGRDDIAIVRIEMLHPIPF 1142
Query 856 QRLAEVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILKSGKQIRISYAGREASAAP 915
R++E LA YPN ++V++ Q+EP NQG W F L + I K R+S R A ++
Sbjct 1143 NRISEALAGYPNAEEVLFVQDEPANQGPWPFYQEHLPELIPNMPKMRRVS---RRAQSST 1199
Query 916 ACGSPYLHAKQQAQLIHDA 934
A G +H ++ QLI +A
Sbjct 1200 ATGVAKVHQLEEKQLIDEA 1218
>P20967 2-oxoglutarate dehydrogenase, mitochondrial [Saccharomyces
cerevisiae (strain ATCC 204508 / S288c)]
Length=1014
Score = 692 bits (1785), Expect = 0.0
Identities = 393/976 (40%), Positives = 570/976 (58%), Gaps = 61/976 (6%)
Query 11 DTELSADSAAYIEELYEQYLTSPTSVTEDWRQYFDKFPKGDQPHSSVREQFLLLGRNSNR 70
D LS +A YI+E+Y+ + P+SV W YF P + + +
Sbjct 42 DNFLSTSNATYIDEMYQAWQKDPSSVHVSWDAYFKNMSNPKIPATKAFQAPPSISNFPQG 101
Query 71 VQAVVQSSVSSDHERRQIGV---LQLIA-AYRNRGHQKAKLDPLGLA----KREDVP-DL 121
+A + + + + +QL+ AY+ RGH KA +DPLG++ K VP +L
Sbjct 102 TEAAPLGTAMTGSVDENVSIHLKVQLLCRAYQVRGHLKAHIDPLGISFGSNKNNPVPPEL 161
Query 122 DLSAHGLTKSDLDTVFNTSNLAI------GKAEATLGEMVETMESIYCGSIGAEYMHIVD 175
L +G +K DLD N + GK++ +L E+V+ +E +YC S G +Y HI
Sbjct 162 TLDYYGFSKHDLDKEINLGPGILPRFARDGKSKMSLKEIVDHLEKLYCSSYGVQYTHIPS 221
Query 176 TKEKRWIQQRLEGARGQFNFTNDQKKALLERLTAAEGLEKFLGNKYVGAKRFGVEGGESF 235
++ W+++R+E + +T DQK+ +L+RLT A E FL K+ KRFG+EG ES
Sbjct 222 KQKCDWLRERIEIPE-PYQYTVDQKRQILDRLTWATSFESFLSTKFPNDKRFGLEGLESV 280
Query 236 IPMMNEIIQRAGSVGCKEVVIGMPHRGRLNLLVNIMGKNPADLFGEFEGKSIHK--KGSG 293
+P + ++ R+ +G +++V+GM HRGRLN+L N++ K +F EF+G S +GSG
Sbjct 281 VPGIKTLVDRSVELGVEDIVLGMAHRGRLNVLSNVVRKPNESIFSEFKGSSARDDIEGSG 340
Query 294 DVKYHQGFSSNVMTPGGE-VHLALAFNPSHLEIVGPVVEGSVRARQVRRKDIGGDD-VLP 351
DVKYH G + T G+ V+L+L NPSHLE PVV G RA + D+ L
Sbjct 341 DVKYHLGMNYQRPTTSGKYVNLSLVANPSHLESQDPVVLGRTRALLHAKNDLKEKTKALG 400
Query 352 VIVHGDAAFAGQGVNQETFQMSQTRGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDV 411
V++HGDAAFAGQGV ET Y+ GGT+H++ NNQ+GFTT DPR ARST Y +D+
Sbjct 401 VLLHGDAAFAGQGVVYETMGFLTLPEYSTGGTIHVITNNQIGFTT-DPRFARSTPYPSDL 459
Query 412 AKMVQSPIFHVNGDDPEAVAFIAQLAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQP 471
AK + +PIFHVN +D EAV FI LA ++RH F D +ID+ +R+ GHNE D+PS TQP
Sbjct 460 AKAIDAPIFHVNANDVEAVTFIFNLAAEWRHKFHTDAIIDVVGWRKHGHNETDQPSFTQP 519
Query 472 LMYQVINKKPTTRTLYADQLVQQKVLDRAEADKLIEDYRSDLEAGNHVANALVLEPNTKM 531
LMY+ I K+ + +Y ++L+ + + + D+ + + E A V +
Sbjct 520 LMYKKIAKQKSVIDVYTEKLISEGTFSKKDIDEHKKWVWNLFEDAFEKAKDYVPSQREWL 579
Query 532 FVDWKPY----------LGHDYTDVWDTTIDINRLKELGEGMRKLPEGFVMQRQVSKVID 581
W+ + L H+ T+V ++T LKELG+ + PEGF + + + +++
Sbjct 580 TAAWEGFKSPKELATEILPHEPTNVPEST-----LKELGKVLSSWPEGFEVHKNLKRILK 634
Query 582 DRLK-MQTGEMPLNWGAAETLAYATLIDEGYLVRITGEDVGRGTFSHRHAKLHNQVDGST 640
+R K ++TGE ++W E LA+ TL+ +G VR++GEDV RGTFS RHA LH+Q +
Sbjct 635 NRGKSIETGE-GIDWATGEALAFGTLVLDGQNVRVSGEDVERGTFSQRHAVLHDQQSEAI 693
Query 641 YIPLCHVKENQPRFALYDSLLSEEAVLAFEYGYATTIPNSLIIWEAQFGDFANCAQVVID 700
Y PL + + F + +S LSE V+ FEYGY+ T P+ L++WEAQFGDFAN AQV+ID
Sbjct 694 YTPLSTLNNEKADFTIANSSLSEYGVMGFEYGYSLTSPDYLVMWEAQFGDFANTAQVIID 753
Query 701 QFIASGETKWERVCGLTMLLPHGFEGQGPEHSSARLERFLQLCAED-------------- 746
QFIA GE KW++ GL + LPHG++GQGPEHSS RLERFLQL ED
Sbjct 754 QFIAGGEQKWKQRSGLVLSLPHGYDGQGPEHSSGRLERFLQLANEDPRYFPSEEKLQRQH 813
Query 747 ---NMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLRHKLATSTLEELATGTFQT 803
N QV+ PTTPA +FH LRRQ R RKP+ + K LLRH LA S+L E G FQ
Sbjct 814 QDCNFQVVYPTTPANLFHILRRQQHRQFRKPLALFFSKQLLRHPLARSSLSEFTEGGFQW 873
Query 804 VIDEVDQ----ITKSDVTRLVLCGGKVYYDLIEKRRELELNNIAVVRIEQLYPYPEQRLA 859
+I++++ TK + RLVL G+VY L ++R L A ++IEQL+P+P +L
Sbjct 874 IIEDIEHGKSIGTKEETKRLVLLSGQVYTALHKRRESLGDKTTAFLKIEQLHPFPFAQLR 933
Query 860 EVLAAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILKSG--KQIRISYAGREASAAPAC 917
+ L +YPN++++VWCQEEP N G+W + PRL+ + ++ K ++ Y GR S A A
Sbjct 934 DSLNSYPNLEEIVWCQEEPLNMGSWAYTEPRLHTTLKETDKYKDFKVRYCGRNPSGAVAA 993
Query 918 GSPYLHAKQQAQLIHD 933
GS LH ++ + D
Sbjct 994 GSKSLHLAEEDAFLKD 1009
>Q02218 2-oxoglutarate dehydrogenase complex component E1 [Homo
sapiens]
Length=1023
Score = 677 bits (1747), Expect = 0.0
Identities = 404/976 (41%), Positives = 564/976 (58%), Gaps = 59/976 (6%)
Query 14 LSADSAAYIEELYEQYLTSPTSVTEDWRQYFDKFPKGDQPHSSVREQFLLLGRNSNRVQA 73
LS S+ Y+EE+Y +L +P SV + W +F G P ++ + L L R S A
Sbjct 50 LSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNAGAPPGTAYQSP-LPLSRGSLAAVA 108
Query 74 VVQSSVSSDHE-----RRQIGVLQLIAAYRNRGHQKAKLDPLGLAKRE---DVPDLDLSA 125
QS V + + V LI AY+ RGH A+LDPLG+ + VP +S+
Sbjct 109 HAQSLVEAQPNVDKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISS 168
Query 126 ------HGLTKSDLDTVFNTSNLA-IGKAEATLG--EMVETMESIYCGSIGAEYMHIVDT 176
+GL +SDLD VF+ IG E+ L E++ +E YC IG E+M I D
Sbjct 169 TDKLGFYGLDESDLDKVFHLPTTTFIGGQESALPLREIIRRLEMAYCQHIGVEFMFINDL 228
Query 177 KEKRWIQQRLEGARGQFNFTNDQKKALLERLTAAEGLEKFLGNKYVGAKRFGVEGGESFI 236
++ +WI+Q+ E G FTN++K+ LL RL + E+FL K+ KRFG+EG E I
Sbjct 229 EQCQWIRQKFE-TPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLI 287
Query 237 PMMNEIIQRAGSVGCKEVVIGMPHRGRLNLLVNIMGKNPADLFGEFEGK-SIHKKGSGDV 295
P + II ++ G V++GMPHRGRLN+L N++ K +F +F+ K +GSGDV
Sbjct 288 PALKTIIDKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGSGDV 347
Query 296 KYHQGFSSNVMT--PGGEVHLALAFNPSHLEIVGPVVEGSVRARQVRRKDIGGDDVLPVI 353
KYH G + + L+L NPSHLE PVV G +A Q D G V+ ++
Sbjct 348 KYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKKVMSIL 407
Query 354 VHGDAAFAGQGVNQETFQMSQTRGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAK 413
+HGDAAFAGQG+ ETF +S YT GTVH+V+NNQ+GFTT DPR ARS+ Y TDVA+
Sbjct 408 LHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTT-DPRMARSSPYPTDVAR 466
Query 414 MVQSPIFHVNGDDPEAVAFIAQLAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLM 473
+V +PIFHVN DDPEAV ++ ++A ++R TF KDVV+DL CYRR GHNE DEP TQPLM
Sbjct 467 VVNAPIFHVNSDDPEAVMYVCKVAAEWRSTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLM 526
Query 474 YQVINKKPTTRTLYADQLVQQKVLDRAEADKLIEDYRSDLE-AGNHVANALVLEPNTKMF 532
Y+ I K+ YA+ LV Q V+++ E ++ I Y E A + +L +
Sbjct 527 YKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFARSKDEKILHIKHWLD 586
Query 533 VDWKPYLGHD----YTDVWDTTIDINRLKELGEGMRKLP-EGFVMQRQVSKVIDDRLKMQ 587
W + D T + + L +G +P E F + +S+++ R +M
Sbjct 587 SPWPGFFTLDGQPRSMSCPSTGLTEDILTHIGNVASSVPVENFTIHGGLSRILKTRGEMV 646
Query 588 TGEMPLNWGAAETLAYATLIDEGYLVRITGEDVGRGTFSHRHAKLHNQ-VDGSTYIPLCH 646
++W AE +A+ +L+ EG +R++G+DV RGTFSHRH LH+Q VD T IP+ H
Sbjct 647 KNRT-VDWALAEYMAFGSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNH 705
Query 647 VKENQPRFALYDSLLSEEAVLAFEYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASG 706
+ NQ + + +S LSE VL FE G+A PN+L++WEAQFGDF N AQ +IDQFI G
Sbjct 706 LWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPG 765
Query 707 ETKWERVCGLTMLLPHGFEGQGPEHSSARLERFLQLCAED-------------------- 746
+ KW R G+ +LLPHG EG GPEHSSAR ERFLQ+C +D
Sbjct 766 QAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQLYDC 825
Query 747 NMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLRHKLATSTLEELATGT-FQTVI 805
N V+ +TP FH LRRQ + P RKP+I+ +PKSLLRH A S+ +E+ GT FQ VI
Sbjct 826 NWVVVNCSTPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEMLPGTHFQRVI 885
Query 806 DEVDQITKS--DVTRLVLCGGKVYYDLIEKRRELEL-NNIAVVRIEQLYPYPEQRLAEVL 862
E ++ +V RL+ C GKVYYDL +R+ ++ +A+ RIEQL P+P L + +
Sbjct 886 PEDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLLKEV 945
Query 863 AAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILKSGKQIRISYAGREASAAPACGSPYL 922
YPN ++ WCQEE KNQG + ++ PRL I ++ + YAGR+ +AAPA G+
Sbjct 946 QKYPNA-ELAWCQEEHKNQGYYDYVKPRLRTTISRAKP---VWYAGRDPAAAPATGNKKT 1001
Query 923 HAKQQAQLIHDALAIE 938
H + +L+ A ++
Sbjct 1002 HLTELQRLLDTAFDLD 1017
>Q5XI78 2-oxoglutarate dehydrogenase complex component E1 [Rattus
norvegicus]
Length=1023
Score = 677 bits (1747), Expect = 0.0
Identities = 404/977 (41%), Positives = 567/977 (58%), Gaps = 59/977 (6%)
Query 14 LSADSAAYIEELYEQYLTSPTSVTEDWRQYFDKFPKGDQPHSSVREQFLLLGRNSNRVQA 73
LS S+ Y+EE+Y +L +P SV + W +F G P ++ + L L R+S A
Sbjct 50 LSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNAGAPPGTAYQSP-LSLSRSSLATMA 108
Query 74 VVQSSVSSDHE-----RRQIGVLQLIAAYRNRGHQKAKLDPLGLAKRE---DVPDLDLSA 125
QS V + + V LI AY+ RGH A+LDPLG+ + VP +S+
Sbjct 109 HAQSLVEAQPNVDKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISS 168
Query 126 ------HGLTKSDLDTVFN--TSNLAIGKAEAT-LGEMVETMESIYCGSIGAEYMHIVDT 176
+GL +SDLD VF+ T+ G+ A L E++ +E YC IG E+M I D
Sbjct 169 TDKLGFYGLHESDLDKVFHLPTTTFIGGQEPALPLREIIRRLEMAYCQHIGVEFMFINDL 228
Query 177 KEKRWIQQRLEGARGQFNFTNDQKKALLERLTAAEGLEKFLGNKYVGAKRFGVEGGESFI 236
++ +WI+Q+ E G FTN++K+ LL RL + E+FL K+ KRFG+EG E I
Sbjct 229 EQCQWIRQKFE-TPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLI 287
Query 237 PMMNEIIQRAGSVGCKEVVIGMPHRGRLNLLVNIMGKNPADLFGEFEGK-SIHKKGSGDV 295
P + II + + G V++GMPHRGRLN+L N++ K +F +F+ K +GSGD+
Sbjct 288 PALKTIIDMSSANGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGSGDM 347
Query 296 KYHQGFSSNVMT--PGGEVHLALAFNPSHLEIVGPVVEGSVRARQVRRKDIGGDDVLPVI 353
KYH G + + L+L NPSHLE PVV G +A Q D G V+ ++
Sbjct 348 KYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKKVMSIL 407
Query 354 VHGDAAFAGQGVNQETFQMSQTRGYTVGGTVHIVINNQVGFTTSDPRDARSTEYCTDVAK 413
+HGDAAFAGQG+ ETF +S YT GTVH+V+NNQ+GFTT DPR ARS+ Y TDVA+
Sbjct 408 LHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTT-DPRMARSSPYPTDVAR 466
Query 414 MVQSPIFHVNGDDPEAVAFIAQLAHDFRHTFRKDVVIDLFCYRRRGHNEADEPSATQPLM 473
+V +PIFHVN DDPEAV ++ ++A ++R+TF KDVV+DL CYRR GHNE DEP TQPLM
Sbjct 467 VVNAPIFHVNSDDPEAVMYVCKVAAEWRNTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLM 526
Query 474 YQVINKKPTTRTLYADQLVQQKVLDRAEADKLIEDYRSDLE-AGNHVANALVLEPNTKMF 532
Y+ I K+ YA+ LV Q V+++ E ++ I Y E A + +L +
Sbjct 527 YKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFTRSKDEKILHIKHWLD 586
Query 533 VDWKPYLGHD----YTDVWDTTIDINRLKELGEGMRKLP-EGFVMQRQVSKVIDDRLKMQ 587
W + D T ++ + L +G +P E F + +S+++ R ++
Sbjct 587 SPWPGFFTLDGQPRSMTCPSTGLEEDILTHIGNVASSVPVENFTIHGGLSRILKTRRELV 646
Query 588 TGEMPLNWGAAETLAYATLIDEGYLVRITGEDVGRGTFSHRHAKLHNQ-VDGSTYIPLCH 646
T ++W AE +A+ +L+ EG VR++G+DV RGTFSHRH LH+Q VD T IP+ H
Sbjct 647 TNRT-VDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNH 705
Query 647 VKENQPRFALYDSLLSEEAVLAFEYGYATTIPNSLIIWEAQFGDFANCAQVVIDQFIASG 706
+ NQ + + +S LSE VL FE G+A PN+L++WEAQFGDF N AQ +IDQFI G
Sbjct 706 LWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFNNMAQCIIDQFICPG 765
Query 707 ETKWERVCGLTMLLPHGFEGQGPEHSSARLERFLQLCAED-------------------- 746
+ KW R G+ +LLPHG EG GPEHSSAR ERFLQ+C +D
Sbjct 766 QAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPNLQEENFDISQLYDC 825
Query 747 NMQVITPTTPAQIFHALRRQAVRPIRKPMIVMSPKSLLRHKLATSTLEELATGT-FQTVI 805
N V+ +TP FH LRRQ + P RKP+IV +PKSLLRH A ++ +E+ GT FQ VI
Sbjct 826 NWIVVNCSTPGNFFHVLRRQILLPFRKPLIVFTPKSLLRHPEARTSFDEMLPGTHFQRVI 885
Query 806 DEVDQITKS--DVTRLVLCGGKVYYDLIEKRRELEL-NNIAVVRIEQLYPYPEQRLAEVL 862
E ++ V RL+ C GKVYYDL +R+ ++ +A+ RIEQL P+P L +
Sbjct 886 PEDGPAAQNPDKVKRLLFCTGKVYYDLTRERKARDMAEEVAITRIEQLSPFPFDLLLKEA 945
Query 863 AAYPNVKDVVWCQEEPKNQGAWLFIAPRLYDDILKSGKQIRISYAGREASAAPACGSPYL 922
YPN ++ WCQEE KNQG + ++ PRL I ++ + YAGR+ +AAPA G+
Sbjct 946 QKYPNA-ELAWCQEEHKNQGYYDYVKPRLRTTIDRAKP---VWYAGRDPAAAPATGNKKT 1001
Query 923 HAKQQAQLIHDALAIEA 939
H + + + A ++A
Sbjct 1002 HLTELQRFLDTAFDLDA 1018
Lambda K H a alpha
0.319 0.135 0.398 0.792 4.96
Gapped
Lambda K H a alpha sigma
0.267 0.0410 0.140 1.90 42.6 43.6
Effective search space used: 19965222
Database: 11b82e4029df2374cf7b992a9706e62e.SwissProt.fasta
Posted date: Jun 4, 2024 1:26 PM
Number of letters in database: 24,246
Number of sequences in database: 24
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
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Data ...
