BLASTP 2.12.0+


Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A.
Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J.
Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of
protein database search programs", Nucleic Acids Res. 25:3389-3402.


Reference for composition-based statistics: Alejandro A. Schaffer,
L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri
I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids
Res. 29:2994-3005.



Database: c364b3e225bfaa2368907160545e572c.SwissProt.fasta
           12 sequences; 4,675 total letters



Query= ACIAD2929

Length=395
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

P31005 NAD-dependent methanol dehydrogenase [Bacillus methanolicus]   224     2e-73
Q59477 1,3-propanediol dehydrogenase [Klebsiella pneumoniae]          223     9e-73
P45513 1,3-propanediol dehydrogenase [Citrobacter freundii]           217     2e-70
P10127 Alcohol dehydrogenase 4 [Saccharomyces cerevisiae (strain ...  217     2e-70
A6ZTT5 Alcohol dehydrogenase 4 [Saccharomyces cerevisiae (strain ...  214     2e-69
F8DVL8 Alcohol dehydrogenase 2 [Zymomonas mobilis subsp. mobilis ...  200     5e-64
P37686 Probable alcohol dehydrogenase [Escherichia coli (strain K...  198     2e-63
P0DJA2 Alcohol dehydrogenase 2 [Zymomonas mobilis subsp. mobilis ...  198     2e-63
Q09669 Alcohol dehydrogenase 4 [Schizosaccharomyces pombe (strain...  196     5e-62
P13604 NADPH-dependent butanol dehydrogenase [Clostridium sacchar...  194     8e-62
P71017 Choline dehydrogenase [Bacillus subtilis (strain 168)]         194     2e-61
A4IP64 Long-chain-alcohol dehydrogenase 1 [Geobacillus thermodeni...  193     4e-61


>P31005 NAD-dependent methanol dehydrogenase [Bacillus methanolicus]
Length=381

 Score = 224 bits (572),  Expect = 2e-73
 Identities = 123/386 (32%), Positives = 207/386 (54%), Gaps = 9/386 (2%)

Query  8    FFCPVKVIAGNAALEHIPFELATLGSKRPMIITDKGVRANHLLEPIEAAFSSTDAEIGYI  67
            FF P   + G  A++ +   L  +G+K+ +I+TD  + +  L E +         ++  I
Sbjct  4    FFIPPASVIGRGAVKEVGTRLKQIGAKKALIVTDAFLHSTGLSEEVAKNIREAGLDVA-I  62

Query  68   FDDVPPDSSLQTVRKAAQLYRDHHCDAIIAIGGGSVIDTSKATNILVSEGGDDLLKYSGA  127
            F    PD +   V +   +++  +CDA+++IGGGS  DT+KA  ++ + GG  +  Y G 
Sbjct  63   FPKAQPDPADTQVHEGVDVFKQENCDALVSIGGGSSHDTAKAIGLVAANGGR-INDYQGV  121

Query  128  HNLPKPLKPFFVIPTTSGTGSEATMVAVVSDTEKNVKMAFASYYLMPHAAILDPRMTLTL  187
            +++ KP+ P   I TT+GTGSE T +AV++D+ + VKM      + P  AI+DP + +  
Sbjct  122  NSVEKPVVPVVAITTTAGTGSETTSLAVITDSARKVKMPVIDEKITPTVAIVDPELMVKK  181

Query  188  PAHLTAMTGMDALTHCVEAYTCLASNPLSDAYASAGIKKISEHLFNVIENPSDSQGRLEL  247
            PA LT  TGMDAL+H +EAY    + P++DA+A   +K I+E+L   + N  D + R  +
Sbjct  182  PAGLTIATGMDALSHAIEAYVAKGATPVTDAFAIQAMKLINEYLPKAVANGEDIEAREAM  241

Query  248  AQASTMAGIAFSNSMVGLVHSLGHALGAVAHLPHGLCMNLFLPYVLEYNKEVNGDKIGEL  307
            A A  MAG+AF+N  +GLVHS+ H +G V  L HG+C ++ +P+V  +N     ++   +
Sbjct  242  AYAQYMAGVAFNNGGLGLVHSISHQVGGVYKLQHGICNSVNMPHVCAFNLIAKTERFAHI  301

Query  308  LLPLAGADIYAQTPANLRADKAISTILAMRDRLFSLTKLPRTLRETGKITEAQLDEVAEK  367
                  A++  +  + L    A    +   +R      +P    E G + E  ++ +A+ 
Sbjct  302  ------AELLGENVSGLSTAAAAERAIVALERYNKNFGIPSGYAEMG-VKEEDIELLAKN  354

Query  368  ALNDGSIIYNPKEANIQDLKAILHKA  393
            A  D     NP+ A +QD+  I+  A
Sbjct  355  AFEDVCTQSNPRVATVQDIAQIIKNA  380


>Q59477 1,3-propanediol dehydrogenase [Klebsiella pneumoniae]
Length=387

 Score = 223 bits (568),  Expect = 9e-73
 Identities = 139/396 (35%), Positives = 213/396 (54%), Gaps = 11/396 (3%)

Query  1    MAKPYYEFFCPVKVIAGNAALEHIPFELATLGSKRPMIITDKGVRA--NHLLEPIEAAFS  58
            M+   +++  P     G  A+  +      LG K+ +++TDKG+RA  +  ++       
Sbjct  1    MSYRMFDYLVPNVNFFGPNAISVVGERCQLLGGKKALLVTDKGLRAIKDGAVDKTLHYLR  60

Query  59   STDAEIGYIFDDVPPDSSLQTVRKAAQLYRDHHCDAIIAIGGGSVIDTSKATNILVSEGG  118
                E+  IFD V P+     VR    ++R   CD I+ +GGGS  D  K   I  +  G
Sbjct  61   EAGIEVA-IFDGVEPNPKDTNVRDGLAVFRREQCDIIVTVGGGSPHDCGKGIGIAATHEG  119

Query  119  DDLLKYSGAHNLPKPLKPFFVIPTTSGTGSEATMVAVVSDTEKNVKMAFASYYLMPHAAI  178
            D L +Y+G   L  PL P   + TT+GT SE T   V+++TE  VK    S+  +P  +I
Sbjct  120  D-LYQYAGIETLTNPLPPIVAVNTTAGTASEVTRHCVLTNTETKVKFVIVSWRNLPSVSI  178

Query  179  LDPRMTLTLPAHLTAMTGMDALTHCVEAYTCLASNPLSDAYASAGIKKISEHLFNVIENP  238
             DP + +  PA LTA TGMDALTH VEAY    +NP++DA A   I+ I+ +L   +   
Sbjct  179  NDPLLMIGKPAALTAATGMDALTHAVEAYISKDANPVTDAAAMQAIRLIARNLRQAVALG  238

Query  239  SDSQGRLELAQASTMAGIAFSNSMVGLVHSLGHALGAVAHLPHGLCMNLFLPYVLEYNKE  298
            S+ Q R  +A AS +AG+AF+N+ +G VH++ H LG +  +PHG+   + LP+V  YN  
Sbjct  239  SNLQARENMAYASLLAGMAFNNANLGYVHAMAHQLGGLYDMPHGVANAVLLPHVARYNLI  298

Query  299  VNGDKIGELLLPLAGADIYAQTPANLRADKAISTILAMRDRLFSLTKLPRTLRETGKITE  358
             N +K  + +  L G +I   +  +  A+KAI+ I     RL     +P+ LR+ G + E
Sbjct  299  ANPEKFAD-IAELMGENITGLSTLD-AAEKAIAAI----TRLSMDIGIPQHLRDLG-VKE  351

Query  359  AQLDEVAEKALNDGSIIYNPKEANIQDLKAILHKAW  394
            A    +AE AL DG+   NP++ N Q++ AI  +A+
Sbjct  352  ADFPYMAEMALKDGNAFSNPRKGNEQEIAAIFRQAF  387


>P45513 1,3-propanediol dehydrogenase [Citrobacter freundii]
Length=387

 Score = 217 bits (553),  Expect = 2e-70
 Identities = 132/395 (33%), Positives = 206/395 (52%), Gaps = 9/395 (2%)

Query  1    MAKPYYEFFCPVKVIAGNAALEHIPFELATLGSKRPMIITDKGVRANHLLEPIEAAFSST  60
            M+   +++  P     G  A+  +      LG K+ +++TDKG+RA       +      
Sbjct  1    MSYRMFDYLVPNVNFFGPNAISVVGERCKLLGGKKALLVTDKGLRAIKDGAVDKTLTHLR  60

Query  61   DAEIGYI-FDDVPPDSSLQTVRKAAQLYRDHHCDAIIAIGGGSVIDTSKATNILVSEGGD  119
            +A I  + FD V P+     VR   +++R  HCD I+ +GGGS  D  K   I  +  GD
Sbjct  61   EAGIDVVVFDGVEPNPKDTNVRDGLEVFRKEHCDIIVTVGGGSPHDCGKGIGIAATHEGD  120

Query  120  DLLKYSGAHNLPKPLKPFFVIPTTSGTGSEATMVAVVSDTEKNVKMAFASYYLMPHAAIL  179
             L  Y+G   L  PL P   + TT+GT SE T   V+++T+  VK    S+  +P  +I 
Sbjct  121  -LYSYAGIETLTNPLPPIVAVNTTAGTASEVTRHCVLTNTKTKVKFVIVSWRNLPSVSIN  179

Query  180  DPRMTLTLPAHLTAMTGMDALTHCVEAYTCLASNPLSDAYASAGIKKISEHLFNVIENPS  239
            DP + L  PA LTA TGMDALTH VEAY    +NP++DA A   I+ I+ +L   +   S
Sbjct  180  DPLLMLGKPAPLTAATGMDALTHAVEAYISKDANPVTDAAAIQAIRLIARNLRQAVALGS  239

Query  240  DSQGRLELAQASTMAGIAFSNSMVGLVHSLGHALGAVAHLPHGLCMNLFLPYVLEYNKEV  299
            + + R  +A AS +AG+AF+N+ +G VH++ H LG +  +PHG+   + LP+V  YN   
Sbjct  240  NLKARENMAYASLLAGMAFNNANLGYVHAMAHQLGGLYDMPHGVANAVLLPHVARYNLIA  299

Query  300  NGDKIGELLLPLAGADIYAQTPANLRADKAISTILAMRDRLFSLTKLPRTLRETGKITEA  359
            N +K  ++      A+   +    L    A    +    RL +   +P+ LR+ G + EA
Sbjct  300  NPEKFADI------AEFMGENTDGLSTMDAAELAIHAIARLSADIGIPQHLRDLG-VKEA  352

Query  360  QLDEVAEKALNDGSIIYNPKEANIQDLKAILHKAW  394
                +AE AL DG+   NP++ N +++  I  +A+
Sbjct  353  DFPYMAEMALKDGNAFSNPRKGNEKEIAEIFRQAF  387


>P10127 Alcohol dehydrogenase 4 [Saccharomyces cerevisiae (strain 
ATCC 204508 / S288c)]
Length=382

 Score = 217 bits (552),  Expect = 2e-70
 Identities = 131/389 (34%), Positives = 203/389 (52%), Gaps = 17/389 (4%)

Query  8    FFCPVKVIAGNAALEHIPFELATLGSKRPMIITDKGVRANHLLEPIEAAFSSTDAEIGYI  67
            F+ P     G  ALE     +     K+ +I+TD G+ A  L   ++      D  +  I
Sbjct  7    FYIPPISFFGEGALEETADYIKNKDYKKALIVTDPGIAAIGLSGRVQKMLEERDLNVA-I  65

Query  68   FDDVPPDSSLQTVRKAAQLYRDHHCDAIIAIGGGSVIDTSKATNILVSEGGDDLLKYSGA  127
            +D   P+ ++  V    ++ ++ + + +++IGGGS  D +KA  +L + GG+ +  Y G 
Sbjct  66   YDKTQPNPNIANVTAGLKVLKEQNSEIVVSIGGGSAHDNAKAIALLATNGGE-IGDYEGV  124

Query  128  HNLPKPLKPFFVIPTTSGTGSEATMVAVVSDTEKNVKMAFASYYLMPHAAILDPRMTLTL  187
            +   K   P F I TT+GT SE T   ++S+ EK +KMA     + P  A+ DP     L
Sbjct  125  NQSKKAALPLFAINTTAGTASEMTRFTIISNEEKKIKMAIIDNNVTPAVAVNDPSTMFGL  184

Query  188  PAHLTAMTGMDALTHCVEAYTCLASNPLSDAYASAGIKKISEHLFNVIENPSDSQGRLEL  247
            P  LTA TG+DALTHC+EAY   ASNP++DA A  GI  I+E L    ++  D + R ++
Sbjct  185  PPALTAATGLDALTHCIEAYVSTASNPITDACALKGIDLINESLVAAYKDGKDKKARTDM  244

Query  248  AQASTMAGIAFSNSMVGLVHSLGHALGAVAHLPHGLCMNLFLPYVLEYNKEVNGDK--IG  305
              A  +AG+AF+N+ +G VH+L H LG   HLPHG+C  + LP+V E N +    K  +G
Sbjct  245  CYAEYLAGMAFNNASLGYVHALAHQLGGFYHLPHGVCNAVLLPHVQEANMQCPKAKKRLG  304

Query  306  ELLLPLAGADIYAQTPANLRADKAISTILAMRDRLFSLTKLPRTLRETGKITEAQLDEVA  365
            E+ L    +            +    TI A+   L     +PR L+E G  TE   + +A
Sbjct  305  EIALHFGASQ-----------EDPEETIKALH-VLNRTMNIPRNLKELGVKTE-DFEILA  351

Query  366  EKALNDGSIIYNPKEANIQDLKAILHKAW  394
            E A++D   + NP +   + + AI+ KA+
Sbjct  352  EHAMHDACHLTNPVQFTKEQVVAIIKKAY  380


>A6ZTT5 Alcohol dehydrogenase 4 [Saccharomyces cerevisiae (strain 
YJM789)]
Length=382

 Score = 214 bits (545),  Expect = 2e-69
 Identities = 130/389 (33%), Positives = 202/389 (52%), Gaps = 17/389 (4%)

Query  8    FFCPVKVIAGNAALEHIPFELATLGSKRPMIITDKGVRANHLLEPIEAAFSSTDAEIGYI  67
            F+ P     G  ALE     +     K+ +I+TD G+ A  L   ++         +  I
Sbjct  7    FYIPPISFFGEGALEETADYIKNKDYKKALIVTDPGIAAIGLSGRVQKMLEERGLNVA-I  65

Query  68   FDDVPPDSSLQTVRKAAQLYRDHHCDAIIAIGGGSVIDTSKATNILVSEGGDDLLKYSGA  127
            +D   P+ ++  V    ++ ++ + + +++IGGGS  D +KA  +L + GG+ +  Y G 
Sbjct  66   YDKTQPNPNIANVTAGLKVLKEQNSEIVVSIGGGSAHDNAKAIALLATNGGE-IGDYEGV  124

Query  128  HNLPKPLKPFFVIPTTSGTGSEATMVAVVSDTEKNVKMAFASYYLMPHAAILDPRMTLTL  187
            +   K   P F I TT+GT SE T   ++S+ EK +KMA     + P  A+ DP     L
Sbjct  125  NQSKKAALPLFAINTTAGTASEMTRFTIISNEEKKIKMAIIDNNVTPAVAVNDPSTMFGL  184

Query  188  PAHLTAMTGMDALTHCVEAYTCLASNPLSDAYASAGIKKISEHLFNVIENPSDSQGRLEL  247
            P  LTA TG+DALTHC+EAY   ASNP++DA A  GI  I+E L    ++  D + R ++
Sbjct  185  PPALTAATGLDALTHCIEAYVSTASNPITDACALKGIDLINESLVAAYKDGKDKKARTDM  244

Query  248  AQASTMAGIAFSNSMVGLVHSLGHALGAVAHLPHGLCMNLFLPYVLEYNKEVNGDK--IG  305
              A  +AG+AF+N+ +G VH+L H LG   HLPHG+C  + LP+V E N +    K  +G
Sbjct  245  CYAEYLAGMAFNNASLGYVHALAHQLGGFYHLPHGVCNAVLLPHVQEANMQCPKAKKRLG  304

Query  306  ELLLPLAGADIYAQTPANLRADKAISTILAMRDRLFSLTKLPRTLRETGKITEAQLDEVA  365
            E+ L    +            +    TI A+   L     +PR L+E G  TE   + +A
Sbjct  305  EIALHFGASQ-----------EDPEETIKALH-VLNRTMNIPRNLKELGVKTE-DFEILA  351

Query  366  EKALNDGSIIYNPKEANIQDLKAILHKAW  394
            E A++D   + NP +   + + AI+ KA+
Sbjct  352  EHAMHDACHLTNPVQFTKEQVVAIIKKAY  380


>F8DVL8 Alcohol dehydrogenase 2 [Zymomonas mobilis subsp. mobilis 
(strain ATCC 10988 / DSM 424 / LMG 404 / NCIMB 8938 / NRRL 
B-806 / ZM1)]
Length=383

 Score = 200 bits (509),  Expect = 5e-64
 Identities = 126/389 (32%), Positives = 214/389 (55%), Gaps = 13/389 (3%)

Query  8    FFCPVKVIAGNAALEHIPFELATLGSKRPMIITDKGVRANHLLEPIEAAFSSTDAEIGYI  67
            F+ P     G  +LE    +L   G K  +I++D  +  + +++ + A    T      +
Sbjct  6    FYIPFVNEMGEGSLEKAIKDLNGSGFKNALIVSDAFMNKSGVVKQV-ADLLKTQGINSAV  64

Query  68   FDDVPPDSSLQTVRKAAQLYRDHHCDAIIAIGGGSVIDTSKATNILVSEGGDDLLKYSGA  127
            +D V P+ ++  V +  ++ +D++ D +I++GGGS  D +KA  ++ + GG+ +  Y G 
Sbjct  65   YDGVMPNPTVTAVLEGLKILKDNNSDFVISLGGGSPHDCAKAIALVATNGGE-VKDYEGI  123

Query  128  HNLPKPLKPFFVIPTTSGTGSEATMVAVVSDTEKNVKMAFASYYLMPHAAILDPRMTLTL  187
                KP  P   I TT+GT SE T   +++D  ++VKMA    ++ P  ++ DP + + +
Sbjct  124  DKSKKPALPLMSINTTAGTASEMTRFCIITDEVRHVKMAIVDRHVTPMVSVNDPLLMVGM  183

Query  188  PAHLTAMTGMDALTHCVEAYTCLASNPLSDAYASAGIKKISEHLFNVIENPSDSQGRLEL  247
            P  LTA TGMDALTH  EAY+  A+ P++DA A      I+++L    +N  D   R  +
Sbjct  184  PKGLTAATGMDALTHAFEAYSSTAATPITDACALKAASMIAKNLKTACDNGKDMPAREAM  243

Query  248  AQASTMAGIAFSNSMVGLVHSLGHALGAVAHLPHGLCMNLFLPYVLEYNKEVNGDKIGEL  307
            A A  +AG+AF+N+ +G VH++ H LG   +LPHG+C  + LP+VL YN  V   ++ ++
Sbjct  244  AYAQFLAGMAFNNASLGYVHAMAHQLGGYYNLPHGVCNAVLLPHVLAYNASVVAGRLKDV  303

Query  308  LLPLAGADIYAQTPANLRADK--AISTILAMRDRLFSLTKLPRTLRETGKITEAQLDEVA  365
             + + G DI     ANL  DK  A +TI A+RD   S+  +P  L E G   E  +  +A
Sbjct  304  GVAM-GLDI-----ANL-GDKEGAEATIQAVRDLAASI-GIPANLTELGAKKE-DVPLLA  354

Query  366  EKALNDGSIIYNPKEANIQDLKAILHKAW  394
            + AL D   + NP++ + ++++ +   A+
Sbjct  355  DHALKDACALTNPRQGDQKEVEELFLSAF  383


>P37686 Probable alcohol dehydrogenase [Escherichia coli (strain 
K12)]
Length=383

 Score = 198 bits (504),  Expect = 2e-63
 Identities = 118/386 (31%), Positives = 206/386 (53%), Gaps = 9/386 (2%)

Query  8    FFCPVKVIAGNAALEHIPFELATLGSKRPMIITDKGVRANHLLEPIEAAFSSTDAEIGYI  67
            FF P   + G  +L      +A  G  R +I+TD  +    +   ++ A    +     I
Sbjct  6    FFIPSVNVIGADSLTDAMNMMADYGFTRTLIVTDNMLTKLGMAGDVQKALEERNI-FSVI  64

Query  68   FDDVPPDSSLQTVRKAAQLYRDHHCDAIIAIGGGSVIDTSKATNILVSEGGDDLLKYSGA  127
            +D   P+ + + V    +L ++++CD++I++GGGS  D +K   ++ + GGD +  Y G 
Sbjct  65   YDGTQPNPTTENVAAGLKLLKENNCDSVISLGGGSPHDCAKGIALVAANGGD-IRDYEGV  123

Query  128  HNLPKPLKPFFVIPTTSGTGSEATMVAVVSDTEKNVKMAFASYYLMPHAAILDPRMTLTL  187
                KP  P   I TT+GT SE T   +++D  +++KMA    ++ P  ++ D  + + +
Sbjct  124  DRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIKMAIVDKHVTPLLSVNDSSLMIGM  183

Query  188  PAHLTAMTGMDALTHCVEAYTCLASNPLSDAYASAGIKKISEHLFNVIENPSDSQGRLEL  247
            P  LTA TGMDALTH +EAY  +A+ P++DA A   +  I+E+L   +E+ S+++ R  +
Sbjct  184  PKSLTAATGMDALTHAIEAYVSIAATPITDACALKAVTMIAENLPLAVEDGSNAKAREAM  243

Query  248  AQASTMAGIAFSNSMVGLVHSLGHALGAVAHLPHGLCMNLFLPYVLEYNKEVNGDKIGEL  307
            A A  +AG+AF+N+ +G VH++ H LG   +LPHG+C  + LP+V  +N +V   ++ + 
Sbjct  244  AYAQFLAGMAFNNASLGYVHAMAHQLGGFYNLPHGVCNAVLLPHVQVFNSKVAAARLRDC  303

Query  308  LLPLAGADIYAQTPANLRADKAISTILAMRDRLFSLTKLPRTLRETGKITEAQLDEVAEK  367
               + G ++  +      A+ A + I A+R+ L     +P  LR+   + E     +A  
Sbjct  304  AAAM-GVNVTGKND----AEGAEACINAIRE-LAKKVDIPAGLRDL-NVKEEDFAVLATN  356

Query  368  ALNDGSIIYNPKEANIQDLKAILHKA  393
            AL D     NP +A  +++ AI   A
Sbjct  357  ALKDACGFTNPIQATHEEIVAIYRAA  382


>P0DJA2 Alcohol dehydrogenase 2 [Zymomonas mobilis subsp. mobilis 
(strain ATCC 31821 / ZM4 / CP4)]
Length=383

 Score = 198 bits (504),  Expect = 2e-63
 Identities = 124/389 (32%), Positives = 213/389 (55%), Gaps = 13/389 (3%)

Query  8    FFCPVKVIAGNAALEHIPFELATLGSKRPMIITDKGVRANHLLEPIEAAFSSTDAEIGYI  67
            F+ P     G  +LE    +L   G K  +I++D  +  + +++ +     +       +
Sbjct  6    FYIPFVNEMGEGSLEKAIKDLNGSGFKNALIVSDAFMNKSGVVKQVADLLKAQGINSA-V  64

Query  68   FDDVPPDSSLQTVRKAAQLYRDHHCDAIIAIGGGSVIDTSKATNILVSEGGDDLLKYSGA  127
            +D V P+ ++  V +  ++ +D++ D +I++GGGS  D +KA  ++ + GG+ +  Y G 
Sbjct  65   YDGVMPNPTVTAVLEGLKILKDNNSDFVISLGGGSPHDCAKAIALVATNGGE-VKDYEGI  123

Query  128  HNLPKPLKPFFVIPTTSGTGSEATMVAVVSDTEKNVKMAFASYYLMPHAAILDPRMTLTL  187
                KP  P   I TT+GT SE T   +++D  ++VKMA    ++ P  ++ DP + + +
Sbjct  124  DKSKKPALPLMSINTTAGTASEMTRFCIITDEVRHVKMAIVDRHVTPMVSVNDPLLMVGM  183

Query  188  PAHLTAMTGMDALTHCVEAYTCLASNPLSDAYASAGIKKISEHLFNVIENPSDSQGRLEL  247
            P  LTA TGMDALTH  EAY+  A+ P++DA A      I+++L    +N  D   R  +
Sbjct  184  PKGLTAATGMDALTHAFEAYSSTAATPITDACALKAASMIAKNLKTACDNGKDMPAREAM  243

Query  248  AQASTMAGIAFSNSMVGLVHSLGHALGAVAHLPHGLCMNLFLPYVLEYNKEVNGDKIGEL  307
            A A  +AG+AF+N+ +G VH++ H LG   +LPHG+C  + LP+VL YN  V   ++ ++
Sbjct  244  AYAQFLAGMAFNNASLGYVHAMAHQLGGYYNLPHGVCNAVLLPHVLAYNASVVAGRLKDV  303

Query  308  LLPLAGADIYAQTPANLRADK--AISTILAMRDRLFSLTKLPRTLRETGKITEAQLDEVA  365
             + + G DI     ANL  DK  A +TI A+RD   S+  +P  L E G   E  +  +A
Sbjct  304  GVAM-GLDI-----ANL-GDKEGAEATIQAVRDLAASI-GIPANLTELGAKKE-DVPLLA  354

Query  366  EKALNDGSIIYNPKEANIQDLKAILHKAW  394
            + AL D   + NP++ + ++++ +   A+
Sbjct  355  DHALKDACALTNPRQGDQKEVEELFLSAF  383


>Q09669 Alcohol dehydrogenase 4 [Schizosaccharomyces pombe (strain 
972 / ATCC 24843)]
Length=422

 Score = 196 bits (498),  Expect = 5e-62
 Identities = 118/394 (30%), Positives = 202/394 (51%), Gaps = 17/394 (4%)

Query  2    AKPYYEFFCPVKVIAGNAALEHIPFELATLGSKRPMIITDKGVRANHLLEPIEAAFSSTD  61
            A P   F+ P   + G   L     ++   G K  +I+TD G+    L + ++A      
Sbjct  43   AMPVSAFYIPSFNLFGKGCLAEAAKQIKMSGFKNTLIVTDPGIIKVGLYDKVKALLEEQS  102

Query  62   AEIGYIFDDVPPDSSLQTVRKAAQLYRDHHCDAIIAIGGGSVIDTSKATNILVSEGGDDL  121
              + +++D V P+ ++  V +  ++ +  +CD++++IGGGS  D +K   +L + GG  +
Sbjct  103  ITV-HLYDGVQPNPTVGNVNQGLEIVKKENCDSMVSIGGGSAHDCAKGIALLATNGGK-I  160

Query  122  LKYSGAHNLPKPLKPFFVIPTTSGTGSEATMVAVVSDTEKNVKMAFASYYLMPHAAILDP  181
              Y G     KP  P   I TT+GT SE T  A++++  +++KMA    + MP  ++ DP
Sbjct  161  ADYEGVDKSSKPQLPLIAINTTAGTASEMTRFAIITEETRHIKMAIIDKHTMPILSVNDP  220

Query  182  RMTLTLPAHLTAMTGMDALTHCVEAYTCLASNPLSDAYASAGIKKISEHLFNVIENPSDS  241
                 LP  LTA TGMDALTH VEAY   A+NP++DA A   I+ ++++L   ++N  D 
Sbjct  221  ETMYGLPPSLTAATGMDALTHAVEAYVSTAANPITDACAVKCIELVNKYLKRAVDNGKDE  280

Query  242  QGRLELAQASTMAGIAFSNSMVGLVHSLGHALGAVAHLPHGLCMNLFLPYVLEYNKE--V  299
            + R  +A A  + G+AF+N+ +G VH++ H LG    +PHG+C  + L +V ++N     
Sbjct  281  EARDNMAYAEFLGGMAFNNASLGYVHAMAHQLGGFYGIPHGVCNAVLLAHVQKFNSRDPR  340

Query  300  NGDKIGELLLPLAGADIYAQTPANLRADKAISTILAMRDRLFSLTKLPRTLRETGKITEA  359
               ++G++   L G + +        A+ A+  I     +L    K+   L + G + E 
Sbjct  341  ANARLGDIAFHL-GCEEHT-------AEAALDRI----SQLVLEVKIRPHLVDLG-VKEK  387

Query  360  QLDEVAEKALNDGSIIYNPKEANIQDLKAILHKA  393
              D + + A+ D     NP +    ++KAI   A
Sbjct  388  DFDVLVDHAMKDACGATNPIQPTHDEVKAIFKSA  421


>P13604 NADPH-dependent butanol dehydrogenase [Clostridium saccharobutylicum]
Length=388

 Score = 194 bits (494),  Expect = 8e-62
 Identities = 124/397 (31%), Positives = 203/397 (51%), Gaps = 39/397 (10%)

Query  8    FFCPVKVIAGNAALEHIPFELATLGSKRPMIITDKGVRANHLLEPIEAAFSSTDAEIGYI  67
            F  P  +  G  +LE    +L  L  K+ M++   G             F   D  +GY+
Sbjct  4    FTLPRDIYYGKGSLE----QLKNLKGKKAMLVLGGGSMKR---------FGFVDKVLGYL  50

Query  68   ---------FDDVPPDSSLQTVRKAAQLYRDHHCDAIIAIGGGSVIDTSKATNILVSEGG  118
                      + V PD S++TV K A+L R    D IIA+GGGS ID +KA  I      
Sbjct  51   KEAGIEVKLIEGVEPDPSVETVFKGAELMRQFEPDWIIAMGGGSPIDAAKAMWIFYEHPE  110

Query  119  ---DDLLKYSGAHNLPKPLKPFFVIPTTSGTGSEATMVAVVSDTEKNVKMAFASYYLMPH  175
               DD+        L    K F  IP+TSGT +E T  +V++D +  +K   A + + P 
Sbjct  111  KTFDDIKDPFTVPELRNKAK-FLAIPSTSGTATEVTAFSVITDYKTEIKYPLADFNITPD  169

Query  176  AAILDPRMTLTLPAHLTAMTGMDALTHCVEAYTCLASNPLSDAYASAGIKKISEHLFNVI  235
             A++D  +  T+P  LTA TGMDALTH +EAY     +P +D  A   I+ I+EHLF   
Sbjct  170  VAVVDSELAETMPPKLTAHTGMDALTHAIEAYVATLHSPFTDPLAMQAIEMINEHLFKSY  229

Query  236  ENPSDSQGRLELAQASTMAGIAFSNSMVGLVHSLGHALGAVAHLPHGLCMNLFLPYVLEY  295
            E   D + R ++  A  +AG+AFSN+++G+ HS+ H  GAV H+PHG    ++LPYV+++
Sbjct  230  E--GDKEAREQMHYAQCLAGMAFSNALLGICHSMAHKTGAVFHIPHGCANAIYLPYVIKF  287

Query  296  NKEVNGDKIGELLLPLAGADIYAQTPANLRADKAISTILAMRDRLFSLTKLPRTLRETG-  354
            N + + ++  ++   +        + A    ++ + +++ +   L    ++P TL+E G 
Sbjct  288  NSKTSLERYAKIAKQI--------SLAGNTNEELVDSLINLVKELNKKMQIPTTLKEYGI  339

Query  355  --KITEAQLDEVAEKALNDGSIIYNPKEANIQDLKAI  389
              +  + ++D ++E+A+ D     NP++ N  ++K I
Sbjct  340  HEQEFKNKVDLISERAIGDACTGSNPRQLNKDEMKKI  376


>P71017 Choline dehydrogenase [Bacillus subtilis (strain 168)]
Length=402

 Score = 194 bits (492),  Expect = 2e-61
 Identities = 108/382 (28%), Positives = 202/382 (53%), Gaps = 15/382 (4%)

Query  5    YYEFFCPVKVIAGNAALEHIPFELATLGSKRPMIITDKGVRANHLLEPIEAAFSSTDAEI  64
            ++ F  P  +  G  A++H   E+A LG  + +++TD G+    + +P+  +      E+
Sbjct  13   FHTFEIPTVIKHGIGAIKHTGEEVAALGVSKALLVTDPGIYKAGVADPVIESLKEAGIEV  72

Query  65   GYIFDDVPPDSSLQTVRKAAQLYRDHHCDAIIAIGGGSVIDTSKATNILVSEGGDDLLKY  124
              +F+ V P+  ++ V + ++LY+  +C+ ++A+GGGS +DT+KA  +  +  G  +L Y
Sbjct  73   -VLFNKVEPNPPVRLVNEGSELYKKENCNGLVAVGGGSSMDTAKAIGVEATHEGS-VLDY  130

Query  125  SGAHNLPKPLK----PFFVIPTTSGTGSEATMVAVVSDTEKNVKMAFASYYLMPHAAILD  180
              A    KPL+    P   IPTT+GTGSE T  AV++D E+  K       +  H  I+D
Sbjct  131  EAADG-KKPLENRIPPLTTIPTTAGTGSEVTQWAVITDEEREFKFNTGGPLIAAHLTIID  189

Query  181  PRMTLTLPAHLTAMTGMDALTHCVEAYTCLASNPLSDAYASAGIKKISEHLFNVIENPSD  240
            P + +++P H+TAMTG+DAL H +E YT   + P++DA A   I+  + ++     +  D
Sbjct  190  PELHVSMPPHVTAMTGIDALAHAIECYTMKFAQPITDAVALMAIEYAAHYIKRAFADGED  249

Query  241  SQGRLELAQASTMAGIAFSNSMVGLVHSLGHALGAVAHLPHGLCMNLFLPYVLEYNKEVN  300
             + R  +AQA+ +AG+++ +   G  H++   LG +  + HG C+   +  V+EYN +  
Sbjct  250  LEARYGMAQAAMLAGLSYGSESAGAAHAMSQTLGGIIPVAHGQCVAAMMGPVMEYNWKGY  309

Query  301  GDKIGELLLPLAGADIYAQTPANLRADKAISTILAMRDRLFSLTKLPRTLRETGKITEAQ  360
             +K   +      A  +    + +  ++A    +     L    ++P TL E G ++   
Sbjct  310  PEKFARI------AKAFGIDTSKMTTEEAAKASVNWMYDLVEDLEVP-TLEEQG-VSPDM  361

Query  361  LDEVAEKALNDGSIIYNPKEAN  382
            ++ ++++A+ D     NP++ N
Sbjct  362  IERLSKEAMKDPQTFGNPRDLN  383


>A4IP64 Long-chain-alcohol dehydrogenase 1 [Geobacillus thermodenitrificans 
(strain NG80-2)]
Length=395

 Score = 193 bits (490),  Expect = 4e-61
 Identities = 126/383 (33%), Positives = 207/383 (54%), Gaps = 17/383 (4%)

Query  17   GNAALEHIPFELATLGSKRPMIITDKGVRANHLLEPIEAAFSSTDAEIGYIFDDVPPDSS  76
            G  AL+ +  E+  LG+K  ++ITD  +    L++ + +        + +++ DV P+  
Sbjct  15   GWGALDQLVPEVKRLGAKHILVITDPMLVKIGLVDQVTSPLRQEGYSV-HVYTDVVPEPP  73

Query  77   LQTVRKAAQLYRDHHCDAIIAIGGGSVIDTSKATNILVSEGGD--DLLKYSGAHNLPKPL  134
            L+T  KA    RD   D +I +GGGS +D +K   +L    G   D L  +G   L K  
Sbjct  74   LETGEKAVAFARDGKFDLVIGVGGGSALDLAKLAAVLAVHDGSVADYLNLTGTRTLEKKG  133

Query  135  KPFFVIPTTSGTGSEATMVAVVS-DTEKNVKMAFASYYLMPHAAILDPRMTLTLPAHLTA  193
             P  +IPTTSGTGSE T ++V+S +T K+V       YL+   AI+DP++T+++P  +TA
Sbjct  134  LPKILIPTTSGTGSEVTNISVLSLETTKDV---VTHDYLLADVAIVDPQLTVSVPPRVTA  190

Query  194  MTGMDALTHCVEAYTCLASNPLSDAYASAGIKKISEHLFNVIENPSDSQGRLELAQASTM  253
             TG+DALTH VEAY  + ++P SD  A A I+ IS  L   + N SD Q R+++A  S +
Sbjct  191  ATGIDALTHAVEAYVSVNASPTSDGLAVAAIRLISRSLRKAVANGSDKQARIDMANGSYL  250

Query  254  AGIAFSNSMVGLVHSLGHALGAVAHLPHGLCMNLFLPYVLEYNKEVNGDKIGELLLPLAG  313
            AG+AF N+ V  VH+L + LG   H+ HG    + LPYV+ Y ++    ++ ++   L G
Sbjct  251  AGLAFFNAGVAGVHALAYPLGGQFHIAHGESNAVLLPYVMGYIRQSCTKRMADIFNALGG  310

Query  314  -ADIYAQTPANLRADKAISTILAMRDRLFSLTKLPRTLRETGKITEAQLDEVAEKALNDG  372
             +   ++  A+ R  + +       +R  +   +P+TL   G I E+ L+ + + A+   
Sbjct  311  NSSFLSEVEASYRCVEEL-------ERFVADVGIPKTLGGFG-IPESALESLTKDAVQQK  362

Query  373  SII-YNPKEANIQDLKAILHKAW  394
             ++  +P      D++AI   A+
Sbjct  363  RLLARSPLPLLEADIRAIYEAAF  385



Lambda      K        H        a         alpha
   0.320    0.135    0.391    0.792     4.96 

Gapped
Lambda      K        H        a         alpha    sigma
   0.267   0.0410    0.140     1.90     42.6     43.6 

Effective search space used: 1422353


  Database: c364b3e225bfaa2368907160545e572c.SwissProt.fasta
    Posted date:  Jun 3, 2024  3:14 PM
  Number of letters in database: 4,675
  Number of sequences in database:  12



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40